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Factors Predictive of Treatment by Australian Breast Surgeons of Invasive Female Breast Cancer by Mastectomy rather than Breast Conserving Surgery

  • Roder, David;Zorbas, Helen;Kollias, James;Pyke, Chris;Walters, David;Campbell, Ian;Taylor, Corey;Webster, Fleur
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.539-545
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    • 2013
  • Background: The National Breast Cancer Audit Database of the Society of Breast Surgeons of Australia and New Zealand is used by surgeons to monitor treatment quality and for research. About 60% of early invasive female breast cancers in Australia are recorded. The objectives of this study are: (1) to investigate associations of socio-demographic, health-system and clinical characteristics with treatment of invasive female breast cancer by mastectomy compared with breast conserving surgery; and (2) to consider service delivery implications. Materials and Methods: Bi-variable and multivariable analyses of associations of characteristics with surgery type for cancers diagnosed in 1998-2010. Results: Of 30,299 invasive cases analysed, 11,729 (39%) were treated by mastectomy as opposed to breast conserving surgery. This proportion did not vary by diagnostic year (p>0.200). With major city residence as the reference category, the relative rate (95% confidence limits) of mastectomy was 1.03 (0.99, 1.07) for women from inner regional areas and 1.05 (1.01, 1.10) for those from more remote areas. Low annual surgeon case load (${\leq}10$) was predictive of mastectomy, with a relative rate of 1.08 (1.03, 1.14) when compared with higher case loads. Tumour size was also predictive, with a relative rate of 1.05 (1.01, 1.10) for large cancers (40+ mm) compared with smaller cancers (<30 mm). These associations were confirmed in multiple logistic regression analysis. Conclusions: Results confirm previous studies showing higher mastectomy rates for residents of more remote areas, those treated by surgeons with low case loads, and those with large cancers. Reasons require further study, including possible effects of surgeon and woman's choice and access to radiotherapy services.

Larval Development of the Grooved Tanner Crab, Chionoecetes tanneri Rathbun, 1893 (Decapoda: Brachyura: Majidae) Described from the Laboratoryreared Specimens

  • Hong, Sung-Yun;Park, Won-Gyu;Perry, R. Ian;Boutillier, James A.
    • Animal cells and systems
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    • v.13 no.1
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    • pp.59-69
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    • 2009
  • This paper documents the defining morphological characteristics of the larval stages of Chionoecetes tanneri Rathbun, 1893, the grooved Tanner crab, from specimens reared in the laboratory. Chionoecetes tanneri larval stages include two zoeae and one megalopa. The first zoea is characterized by: six setae on the posterior margin of the carapace; postero-lateral spines on abdominal somites 3 and 4, extending beyond the posterior margin of adjacent somites and bearing 9-10 spinnules; 12 plumose setae and one stout distal plumose seta present on the margin of the scaphognathite of the maxilla; and one fused lateral spine and one articulated dorso-medial spine on each fork of the telson. The second zoea is characterized by: 9 setae on the postero-lateral margin of the carapace; a serrated mandible molar; a mandibular palp bud; 25-26 plumose setae on the margin of the scaphognathite of the maxilla; pereiopods with well-developed gills and buds; and four pairs of stout setae on the posterior margin of the telson. For the megalopal stage, the distinguishing characteristics include: a rostral spine equal in length to the supraorbital spine; six setae on the exopod of the uropod; and a single spine on the ischium of the second pereiopod. This study allows C. tanneri larvae to be distinguished from the larvae of known sympatric congeners. This information provides a basic taxonomic tool for researchers in fisheries management and zooplankton ecology who are addressing issues related to trophic interactions, metapopulation dynamics and ecosystem impacts in the evolving marine resource management strategies in the North Pacific, and those related to Chionoecetes species in particular.

Overview of Seismic Loads and Application of Local Code Provisions for Tall Buildings in Baku, Azerbaijan

  • Choi, Hi Sun;Sze, James;Ihtiyar, Onur;Joseph, Leonard
    • International Journal of High-Rise Buildings
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    • v.3 no.1
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    • pp.65-71
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    • 2014
  • Baku, the capital of Azerbaijan, has seen a boom in construction in recent years. The old Baku city has been rapidly transforming into a new hub of high-rise buildings and lively cultural centers hosting the Euro Vision Song Contest in 2012 and European Games in 2015. A major population shift to Baku from its suburbs and the countryside has resulted in the doubling of Baku's population in the 4 years between 2009 and 2013. As of January 2013, Baku's population reached four million people, 43% of the citizens in Azerbaijan according to The State Statistical Committee of Azerbaijan. With this trend, the city needs more high-rise buildings to accommodate rapidly increasing demands for more housing and business space. Until the Azerbaijan Seismic Building Code was published in 2010 and became effective, many different seismic criteria, in terms of building codes and seismic intensities, were used for all new high-rise projects in Baku. Some designers used the SNIP (Russian) code with seismic level 9 or level 8 with 1 point penalty. Others used the Turkish code with Seismic Zone 1, UBC 97 with Zone 2 through 4, or IBC with Sa = 0.75 g through 1.0 g. The seismic intensity is now clarified with the Azerbaijan Seismic Building Code. However, the Azerbaijan Seismic Building Code is appropriate for low-rise buildings applications but may be inappropriate for high-rise project applications. This is because the code-defined response spectrum yields unrealistically conservative seismic forces for high-rise buildings with long periods, as compared to those determined by other internationally accepted building codes. This paper provides observations and recommendations for code-based seismic load assessment of high-rise buildings in the Baku area.

Modeling of cyclic joint shear deformation contributions in RC beam-column connections to overall frame behavior

  • Shin, Myoungsu;LaFave, James M.
    • Structural Engineering and Mechanics
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    • v.18 no.5
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    • pp.645-669
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    • 2004
  • In seismic analysis of moment-resisting frames, beam-column connections are often modeled with rigid joint zones. However, it has been demonstrated that, in ductile reinforced concrete (RC) moment-resisting frames designed based on current codes (to say nothing of older non-ductile frames), the joint zones are in fact not rigid, but rather undergo significant shear deformations that contribute greatly to global drift. Therefore, the "rigid joint" assumption may result in misinterpretation of the global performance characteristics of frames and could consequently lead to miscalculation of strength and ductility demands on constituent frame members. The primary objective of this paper is to propose a rational method for estimating the hysteretic joint shear behavior of RC connections and for incorporating this behavior into frame analysis. The authors tested four RC edge beam-column-slab connection subassemblies subjected to earthquake-type lateral loading; hysteretic joint shear behavior is investigated based on these tests and other laboratory tests reported in the literature. An analytical scheme employing the modified compression field theory (MCFT) is developed to approximate joint shear stress vs. joint shear strain response. A connection model capable of explicitly considering hysteretic joint shear behavior is then formulated for nonlinear structural analysis. In the model, a joint is represented by rigid elements located along the joint edges and nonlinear rotational springs embedded in one of the four hinges linking adjacent rigid elements. The connection model is able to well represent the experimental hysteretic joint shear behavior and overall load-displacement response of connection subassemblies.

Evaluation of Fungicides for Dollar Spot Control on Creeping Bentgrass and Annual Bluegrass Putting Green (크리핑벤트그래스와 애뉴얼블루그래스 그린에서 동전마름병에 대한 살균제 효과 평가)

  • Popko, James;Ok, Chang-Ho;Jung, Geun-Hwa
    • Asian Journal of Turfgrass Science
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    • v.24 no.2
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    • pp.161-164
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    • 2010
  • Dollar spot, caused by Sclerotinia homoeocarpa F.T. Bennett, is the most economically important turfgrass disease on golf courses in North America due to its persistent nature. Fungicides, plant growth regulators, and other products were evaluated for preventative control of dollar spot and the secondary effects on brown patch and Pythium in a mixed stand of creeping bentgrass and annual bluegrass golf course putting green. Most fungicides provided excellent control of dollar spot throughout the trial but Rhapsody alone did not provide adequate control. Civitas applied alone and tank-mixed with Banner MAXX(R) and Daconil Ultrex(R) provided acceptable control throughout the study. No phytotoxicity was observed on any of the treatments applied but a darker green color and reduction in turfgrass growth was observed in a treatment with plant growth regulator, Trimmit. Treatments that contained Civitas and the Civitas Harmonizer also exhibited green pigmentation.

Seeking Platform Finance as an Alternative Model of Financing for Small and Medium Enterprises in Korea (중소기업 대안금융으로서 플랫폼 금융의 모색)

  • Chung, Jay M.;Park, Jaesung James
    • The Journal of Small Business Innovation
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    • v.20 no.3
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    • pp.49-68
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    • 2017
  • Platform finance is emerging as an alternative finance for SMEs by suggesting a new funding source based on a new technology named FinTech. The essence of this business is the adapting ICT challenges to the financial industry that can adequately reflect risk assessment using Big Data and effectively meet individual risk-return preference. Thus, this is evolving as an alternative to existing finance in the form of P2P loans for Micro Enterprises and supply-chain finance for SMEs that need more working capital. Platform finance in Korea, however, is still at an infant stage and requires policy support. This can be summarized as follows: "Participation of institutional investors and the public sector," meaning that public investors provide seed money for the private investors to crowd in for platform finance. "Negative system in financial regulations," with current regulations to be deferred for new projects, such as Sandbox in the UK. In addition, "Environment for generous use of data," allowing discretionary data sharing for new products," and "Spreading alternative investments," fostering platform finance products as alternative investments in the low interest-rate era.

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POWER SPECTRUM ANALYSIS OF THE OMC1 IMAGE AT 1.1MM WAVELENGTH

  • Youn, So-Young;Kim, Sung-Eun
    • Journal of The Korean Astronomical Society
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    • v.45 no.4
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    • pp.93-99
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    • 2012
  • We present a 1.1mm emission map of the OMC1 region observed with AzTEC, a new large-format array composed of 144 silicon-nitride micromesh bolometers, that was in use at the James Clerk Maxwell Telescope (JCMT). These AzTEC observations reveal dozens of cloud cores and a tail of filaments in a manner that is almost identical to the submillimeter continuum emission of the entire OMC1 region at 450 and $850{\mu}m$. We perform Fourier analysis of the image with a modified periodogram and the density power spectrum, which provides the distribution of the length scale of the structures, is determined. The expected value of the periodogram converges to the resulting power spectrum in the mean squared sense. The present analysis reveals that the power spectrum steepens at relatively smaller scales. At larger scales, the spectrum flattens and the power law becomes shallower. The power spectra of the 1.1mm emission show clear deviations from a single power law. We find that at least three components of power law might be fitted to the calculated power spectrum of the 1.1mm emission. The slope of the best fit power law, ${\gamma}{\approx}-2.7$ is similar to those values found in numerical simulations. The effect of beam size and the noise spectrum on the shape and slope of the power spectrum are also included in the present analysis. The slope of the power law changes significantly at higher spatial frequency as the beam size increases.

Core formation in different environments: Planck Galactic Cold Clumps (PGCCs) in the λ Orionis cloud, Orion A and Orion B clouds

  • Yi, HeeWeon;Lee, Jeong-Eun;Liu, Tie;Kim, Kee-Tae;Wu, Yuefang
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.37.4-38
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    • 2016
  • Based on the $850{\mu}m$ dust continuum data from James Clerk Maxwell Telescope (JCMT)/SCUBA-2, we compare overall properties of Planck Galactic Cold Clumps (PGCCs) in the ${\lambda}$ Orionis cloud with PGCCs in other molecular clouds, Orion A and Orion B. The Orion A and Orion B clouds are well known active star-forming region, while, ${\lambda}$ Orionis cloud has a different environment associating with prominent OB associations and a giant H II region. PGCCs in the ${\lambda}$ Orionis cloud have higher dust temperatures (Td~16.08 K) and lower values of dust emissivity (${\beta}{\sim}1.65$) than Orion A and Orion B clouds. In addition, we found the lowest detection rate (16 %, 8 out of 50) of PGCCs at $850{\mu}m$ in the ${\lambda}$ Orionis cloud while among three regions; Orion A and Orion B clouds show much higher detection rates of ~ 76 % (23 out of 30) and 56 % (9 out of 16), respectively. The detected 8 PGCCs in the ${\lambda}$ Orionis cloud have substructures and we identified 15 cores. The cores also show much lower median values of size (~0.08 pc), column density (~ ), number density (~ ), and mass (~ ) compared with other cores in the Orion A and Orion B clouds. These core properties in the ${\lambda}$ Orionis cloud can be attributed to the compression and external heating by the nearby H II region, which may prevent the PGCCs from forming gravitationally bound structures and eventually disperse them. These results well present the negative stellar feedback to core formation.

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Effect of Chemically Treated / Untreated Carbon Cloth: Potential Use as Electrode Materials in the Capacitive Deionization Process of Desalination of Aqueous Salt Solution

  • Thamilselvan, Annadurai;Nesaraj, A Samson;Noel, Michael;James, E.J.
    • Journal of Electrochemical Science and Technology
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    • v.6 no.4
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    • pp.139-145
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    • 2015
  • Capacitive deionization (CDI) process is a novel approach for desalination of an aqueous salt solution. In the present study, an activated carbon cloth (ACC) is proposed as effective electrode material. Initially the carbon cloth was activated in 1 M and 8 M HNO3 for 9 hours at room temperature. The untreated and chemically activated carbon cloth (ACC) electrode materials were subjected to BET surface area measurements in order to get information about their specific surface area, average pore size, total pore volume and micropore area. The above materials were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM) also. The electrochemical studies for the electrodes were done using cyclic voltammetry (CV) in 0.1 M Na2SO4 medium. From the studies, it was found that resistivity of the activated carbon cloth electrodes (treated in 1 M and 8 M HNO3) was decreased significantly by the chemical oxidation in nitric acid at room temperature and its capacitance was found to be 90 F/g (1 M HNO3) and 154 F/g (8 M HNO3) respectively in 0.1 M Na2SO4 solution. The capacitive deionization behavior of a single cell CDI with activated carbon cloth electrodes was also studied and reported in this work.

Study on the temperature and optical wavelength sensing composites as smart materials (온도 및 광파장을 감지하는 스마트 복합재료에 관한 연구)

  • ;Delbert E. Day;James O. Stoffer
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.6 no.3
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    • pp.439-448
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    • 1996
  • The possibility of application or the transparent BK10 glass fiber/PMMA composites as a temperature-or wavelength-sensors was studied. Measurement of diameter and refractive index for glass fibers to be reinforced to PMMA as a function of drawing speed and temperature was done and the appropriate coating methods and solvent for coupling agent was researched. $T_{max%}$ value at which the maximum transmission for the composites occurs could be controlled to be in $31~50^{\circ}C$ by the processing factors such as fiber diameter, fiber vol%, molecular wt. of PMMA. Furthermore, with different wavelength other than 589.3 nm, the $T_{max%}$ value could be controlled to be in $35~55^{\circ}C$. For the sensibility of wavelength for the composites, there was not a wavelength ($\lamda_{max%}$) showing maximum transmission.

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