• Asian-Australasian Journal of Animal Sciences
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• v.31 no.2
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• pp.278-286
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• 2018

Objective: Two experiments were conducted to evaluate vitamin $D_3$ administration to nursery pigs by injection or in drinking water on serum 25-hydroxycholecalciferol ($25-OHD_3$) concentrations. Methods: At weaning, 51 pigs (27 and 24 pigs in experiments 1 and 2, respectively) were allotted to vitamin $D_3$ treatments. Treatments in experiment 1 were: i) control (CON), no vitamin administration beyond that in the diet, ii) intramuscular (IM) injection of 40,000 IU of vitamin $D_3$ at weaning, and iii) water administration, 5,493 IU of vitamin $D_3/L$ drinking water for 14 d post-weaning. Treatments in experiment 2 were: i) control (CON), no vitamin administration, and ii) water administration, 92 IU of $d-{\alpha}-tocopherol$ and 5,493 IU of vitamin $D_3/L$ drinking water for 28 d post-weaning. The lightest 2 pigs within each pen were IM injected with an additional 1,000 IU of $d-{\alpha}-tocopherol$, 100,000 IU of retinyl palmitate, and 100,000 IU of vitamin $D_3$. Results: In both experiments, serum $25-OHD_3$ was changed after vitamin $D_3$ administration (p<0.05). In experiment 1, injection and water groups had greater values than CON group through d 35 and 21 post-administration, respectively (p<0.05). In experiment 2, serum values peaked at d 3 post-administration in the injection groups regardless of water treatments (p<0.05) whereas CON and water-only groups had peaks at d 14 and 28 post-administration, respectively (p<0.05). Even though the injection groups had greater serum $25-OHD_3$ concentrations than the non-injection groups through d 7 post-administration regardless of water treatments (p<0.05), the water-only group had greater values than the injection-only group from d 21 post-administration onward (p<0.05). Conclusion: Serum $25-OHD_3$ concentrations in pigs increased either by vitamin $D_3$ injection or drinking water administration. Although a single vitamin $D_3$ injection enhanced serum $25-OHD_3$ concentrations greater than water administration in the initial period post-administration, a continuous supply of vitamin $D_3$ via drinking water could maintain higher serum values than the single injection.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2431-2440
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• 2015

Background: Registry data from four major public hospitals indicate trends in clinical care and survival from colorectal cancer over three decades, from 1980 to 2010. Materials and Methods: Kaplan-Meier productlimit estimates and Cox proportional hazards models were used to investigate disease-specific survival and multiple logistic regression analyses to explore first-round treatment trends. Results: Five-year survivals increased from 48% for 1980-1986 to 63% for 2005-2010 diagnoses. Survival increases applied to each ACPS stage (Australian Clinico-Pathological Stage), and particularly stage C (an increase from 38% to 68%). Risk of death from colorectal cancer halved (hazards ratio: 0.50 (0.45, 0.56)) over the study period after adjusting for age, sex, stage, differentiation, primary sub-site, health administrative region, and measures of socioeconomic status and geographic remoteness. Decreases in stage were not observed. Survivals did not vary by sex or place of residence, suggesting reasonable equity in service access and outcomes. Of staged cases, 91% were treated surgically with lower surgical rates for older ages and more advanced stage. Proportions of surgical cases having adjuvant therapy during primary courses of treatment increased for all stages and were highest for stage C (an increase from 5% in 1980-1986 to 63% for 2005-2010). Radiotherapy was more common for rectal than colonic cases. Proportions of rectal cases receiving radiotherapy increased, particularly for stage C where the increase was from 8% in 1980-1986 to 60% in 2005-2010. The percentage of stage C colorectal cases less than 70 years of age having systemic therapy as part of their first treatment round increased from 3% in 1980-1986 to 81% by 1995-2010. Based on survey data on uptake of adjuvant therapy among those offered this care, it is likely that all these younger patients were offered systemic treatment. Conclusions: We conclude that pronounced increases in survivals from colorectal cancer have occurred at major public hospitals in South Australia due to increases in stage-specific survivals. Use of adjuvant therapies has increased and the patterns of change accord with clinical guideline recommendations. Reasons for sub-optimal use of radiotherapy for rectal cases warrant further investigation, including the potential for limited rural access to impede uptake of treatments at metropolitan-based radiotherapy centres.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2465-2472
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• 2015

Background: The Quality Audit (BQA) program of the Breast Surgeons of Australia and New Zealand (NZ) collects data on early female breast cancer and its treatment. BQA data covered approximately half all early breast cancers diagnosed in NZ during roll-out of the BQA program in 1998-2010. Coverage increased progressively to about 80% by 2008. This is the biggest NZ breast cancer database outside the NZ Cancer Registry and it includes cancer and clinical management data not collected by the Registry. We used these BQA data to compare socio-demographic and cancer characteristics and survivals by ethnicity. Materials and Methods: BQA data for 1998-2010 diagnoses were linked to NZ death records using the National Health Index (NHI) for linking. Live cases were followed up to December $31^{st}$ 2010. Socio-demographic and invasive cancer characteristics and disease-specific survivals were compared by ethnicity. Results: Five-year survivals were 87% for Maori, 84% for Pacific, 91% for other NZ cases and 90% overall. This compared with the 86% survival reported for all female breast cases covered by the NZ Cancer Registry which also included more advanced stages. Patterns of survival by clinical risk factors accorded with patterns expected from the scientific literature. Compared with Other cases, Maori and Pacific women were younger, came from more deprived areas, and had larger cancers with more ductal and fewer lobular histology types. Their cancers were also less likely to have a triple negative phenotype. More of the Pacific women had vascular invasion. Maori women were more likely to reside in areas more remote from regional cancer centres, whereas Pacific women generally lived closer to these centres than Other NZ cases. Conclusions: NZ BQA data indicate previously unreported differences in breast cancer biology by ethnicity. Maori and Pacific women had reduced breast cancer survival compared with Other NZ women, after adjusting for socio-demographic and cancer characteristics. The potential contributions to survival differences of variations in service access, timeliness and quality of care, need to be examined, along with effects of comorbidity and biological factors.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2707-2711
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• 2014

Introduction: Smoking prevalence among the medical students is high in China. Therefore, understanding the smoking motivations of medical students is crucial for smoking control, but currently there are no scales questionnaires customized for probing the smoking motivations of medical students. This aim of study was to test and modify a questionnaire for investigating smoking motivations among medical students. Methods: A cross-sectional survey was conducted among 1,125 medical students at Xuzhou Medical College in China in 2012.The model fit and validity was assessed by confirmatory factor analysis (CFA) and the reliability was tested by single-item reliability, composite reliability, and item-total correlation. Results: The prevalence of smoking was 9.84 % among study population. In the modified scales, the global fit indices identified a CFI value of 0.96, TLI was 0.96, and the RMSEA was 0.063. CFA supported the two dimensional structure of the instrument. The average variance extracted ranged from 0.45 to 0.62. All single-item reliability scores were greater than 0.20, and the composite reliability ranged from 0.74 to 0.91. Conclusion: Modified scales could be the preliminary instrument used in evaluating the smoking motivations of medical students. However, it should be further assessed using other forms and methods of validity and reliability, additional motivations of smoking, and the survey of other medical colleges in China.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7657-7661
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• 2013

Background: This study concerns uptake and results of colorectal cancer (CRC) screening of government servant as part of the Health Screening Program that was conducted in Brunei Darussalam in 2009. Materials and Methods: Government servants above the age of 40 or with family history of CRC were screened with a single fecal occult blood test (FIT, immunohistochemistry). Among 11,576 eligible subjects, 7,360 (66.9%) returned their specimen. Subjects with positive family history of CRC (n=329) or polyps (n=135) were advised to attend clinics to arrange screening. All the subjects with positive FIT (n=142, 1.9%) were referred to the endoscopy unit for counselling for screening colonoscopy. Results: Overall only 17.7% of eligible subjects attended for screening; 54.9% (n=79/142) of positive FIT, 8.8% (n=29/329) of positive family history of CRC and none with history of polyps (n=0/135). Of these, only 54 patients (50.5%) agreed for colonoscopy, 52 (48.6%) declined as they were asymptomatic, and one was not offered (0.9%) due to his very young age. On screening colonoscopy, 12.9% (n=7) had advanced lesions including a sigmoid carcinoma in situ and six advanced polyps. The other findings included non advanced polyps (n=21), diverticular (n=11) and hemorrhoids (n=26). One patient who missed his screening colonoscopy appointment re-presented two years later and was diagnosed with advanced right sided CRC. All the advanced lesions were detected in patients with positive FIT, giving a yield of 20.5% for advanced lesions including cancers in the 5.1% FIT positive subjects. Conclusions: Our study showed screening for CRC even with a single FIT was effective. However, the uptake rate was poor with just over half of the patients agreeing to screening colonoscopy. Measures to increase public awareness are important. Since one limitation of our study was the relatively small sample size, larger studies should be conduced in future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.6
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• pp.1969-1977
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• 2010

James Cameron's "Avatar" has broken the national record of movie ticket sales, and it caused the boom of 3D and 3D related fields. This research is focused on the appropriate ways to embrace the stereoscopic 3D cinema and the assumable result in Korea. The new stereoscopic 3D is different from the old fashioned analogue 3D, and it has many possibilities that may influence Korean film industry. Since 1990s, the number of Korean film school has increased drastically, and many of those who graduated from the schools would experience fierce job market. 3D converting projects that require a lot of film majored personnels would solve the overly supplied film majored professionals. Through Korea's hundreds of film schools, when they include 3D filmmaking in their curriculum, they can train and educate 3D related staff such as stereographer, convergence puller, and depth continuity artists, and Korea can be an important 3D staff train center in the world. Educating 3D filmmaking can produce a noticeable result in terms of accepting 3D cinema. Stereoscopic 3D cinema has many possibilities in many fields not only in cinema but also almost every fields that related to the imagery. With government's supports, the investments from the 3D related corporations, and 3D education in colleges would be fast and efficient way to embrace and accept stereoscopic 3D cinema in Korea in terms of the size and the profit.

• Strategy21
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• s.42
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• pp.114-153
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• 2017

고도화 및 가시화되고 있는 북한의 '잠수함발사탄도미사일(SLBM: Submarine Launched Ballistic Missile)'위협에 대응하기 위한 효과적인 전략수단으로써 핵추진잠수함의 필요성에 대한 국민적 관심이 고조되고 있다. 핵추진잠수함의 전략적 가치에 대한 논의가 활발히 진행되고 있는 가운데, 주변국과의 갈등과 국제사회의 비핵화 규범의 미 준수 논란 등 핵추진잠수함 확보과정에서 야기될 수 있는 대·내외의 정치·외교적 파장에 대한 우려의 목소리 또한 높아지고 있다. 그러나, 핵추진잠수함의 필요성 및 확보와 관련한 지금까지의 대부분의 논의들은 한국의 '내부적 논의(Just our own scenario)'에 그치는 한계를 보이고 있다. 전략무기체계로써의 상징성과 그에 따르는 대외적 민감성을 고려 시 일방적이고 독자적인 핵추진잠수함 확보노력은 과정상의 시행착오와 불확실성을 더욱 가중시켜 정책적 실패로 귀결될 수 있는 위험성을 내포하고 있다. 특히, 한반도 평화와 아태지역의 안전보장이라는 공동의 전략적 목표를 공유하고 있는 동맹국인 미국의 공감대와 지지가 뒷받침되지 않은 독자적인 핵추진잠수함 확보노력은 큰 난항이 예상되며 자칫 서로간의 '전략적 신뢰(Strategic Trust)'를 무너뜨려 '한미동맹의 결속력(Alliance Cohesion)'을 약화시키는 요인으로 작용할 수 있다. 미국의 동의와 지지에 기반한 핵추진잠수함 확보를 위해서는 한국의 핵추진잠수함 확보가 동맹의 전략목표 및 미국의 전략적 이해관계에 미칠 수 있는 긍정적, 부정적 효과에 대한 충분한 검토와 논의가 선행되어야 한다. 한미동맹의 공동의 전략목표와 미국의 전략적 이익에 상충하는 한국의 핵추진잠수함 확보시도는 성공 가능성이 낮기 때문이다. 본 연구에서는 현실화되고 있는 북한의 핵위협에 대응하고 지역안전보장에 기여할 수 있는 미국과의 연합방위력 증강차원에서의 한국의 핵추진잠수함의 전략적 효용성을 분석하였다. 더불어, 한국의 핵추진잠수함 확보과정에서 야기될 수 있는 대·내외의 기술적, 정치·외교적 사안들을 살펴본 후 한미동맹 차원에서의 정책적 해결방안을 제시하였다. 연구목적을 위해 유사한 역사적 사례연구를 통해 교훈을 도출하였으며, 미국 오바마 1기 행정부에서 미국의 아태지역 및 대북정책을 주도한 전 미국 국무부부장관 제임스 스타인버그(James Steinberg) 및 여러 미국 내 한반도 전문가들의 의견을 수렴하였다. 본 연구가 한국의 핵잠수함 확보를 위한 한미간 발전적 논의의 시발점이 되기를 기대한다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2017.11a
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• pp.79-85
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• 2017

It is critical that passengers should be given timely and correct escape or evacuation guidance from captain and crews when there are hazardous situations in a ship. Otherwise the consequences could be disastrous as "SEWOL Ferry" the South Korean passenger ship which sank in southern coastal area on 16th April 2014. Due to the captain's delayed evacuation decision and lack of sufficient number of crews to guide passengers' evacuation, the accident recorded many casualties, most of whom were high school students (302 passengers sank down with the ship while 172 rescued). Building a passenger ship with well-designed physical escape routes is one thing and guiding passengers to those escape routes in real disaster situation is another. Passengers get panic and move to a wrong direction, bottleneck makes situation worse, and even crews get panic also - passive static escape route signage and small number of trained crews might not be enough to take care of them. SESS (Smart Escape Support System) is being developed sponsored by South Korea Ministry of Ocean and Fisheries starting from 2016 with 4 years of roadmap. SESS comprises multiple active dynamic signage devices which communicate with real-time escape routing server software via LoRa (Long Range) proprietary wireless network.

• The korean journal of orthodontics
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• v.40 no.1
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• pp.34-39
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• 2010

Objective: The aim of the present study was to evaluate the changes in tooth mobility following orthodontic treatment and to obtain information regarding the guideline of retainer wear duration during the post-treatment period. Methods: The sample consisted of twenty patients who had been treated with edgewise appliances. The mobility of the maxillary teeth from the central incisor to the first molar was measured bilaterally by way of the $Periotest^{(R)}$, a non-invasive, electronic device that provides an objective measurement of the reaction of the periodontium to a defined impact load. Tooth mobility was monitored at the time of the removal of the orthodontic appliances and subsequently at three-month intervals during the two years following appliance removal. Results: Tooth mobility decreased rapidly for the first six months and then decreased at a slower rate during the next six months; no statistically significant decrease in mobility was observed during the second year following appliance removal. Conclusions: The results of the present study suggest that adequate tooth stabilization is critical during the first six months following appliance removal and that continued wearing of retainers is recommended at least until twelve months after the completion of orthodontic treatment.

• Journal of The Korean Astronomical Society
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• v.51 no.3
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• pp.49-63
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• 2018

We carry out a study of Sub-Millimeter Galaxies (SMGs) in the AKARI NEP-Deep field using the James Clerk Maxwell Telescope (JCMT) SCUBA-2 $850{\mu}m$ source catalog, released as part of the SCUBA-2 Cosmology Legacy Survey (S2CLS) program. The SCUBA-2 $850{\mu}m$ map has a root mean square (rms) noise of $1.2mJy\;beam^{-1}$ and covers an area of $0.60degree^2$. We find four SMGs which have counterparts to Herschel sources with spectroscopic redshifts in the literature. In addition, three dust obscured galaxies (DOGs) detected in Herschel bands are selected as a comparison sample. We derive IR luminosities of SMGs using the CIGALE code, which are similar to those of high redshift SMGs from previous studies. The contribution of AGN to the total IR luminosity in SMGs (2%-11%) is smaller than the lower limit for the one in DOGs (19%-35%), which is consistent with the expectation from the evolutionary scenario of massive galaxies. We search for SMGs in overdense regions as protocluster candidates and investigate four regions, including candidates around three DOGs. Finally, we argue that follow-up spectroscopic observation for the NEP-Deep field will provide crucial information to understand the role of SMGs in the evolution of massive galaxies.