• Title/Summary/Keyword: Jae Chun

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Synthesis of Acyclonucleosides (4) - Synthesis of 3 ' -substituted secouridines4

  • Cho, Young-Hoon;Yang, Jae-Wook;Chun, Byung-Kwon;Kim, Moon-Hwan;Chun, Moon-Woo;Chung, Won-Keun
    • Archives of Pharmacal Research
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    • v.12 no.4
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    • pp.300-305
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    • 1989
  • The synthetic study of 3' azido and 3'-fluoro secouridines toward development of new antiviral agents is described. These acyclic nucleosides were synthesized from uridine by the method of ring opening reaction of sugar moiety.

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Effect of Processing Conditions on the Weldlines and Shinkage of Injection-Molded parts by using both CAE and Experiment (사출성형 CAE해석을 이용한 성형품의 Weldline과 변형에 관한 연구)

  • Chung, Jae-Youp;Kim, Dong-Hak
    • Proceedings of the KAIS Fall Conference
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    • 2008.11a
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    • pp.371-374
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    • 2008
  • 본 연구에서는 무도장 Weldless 평가금형을 이용하여 사출성형 공정조건에 따라 다양한 형태의 변형이 생기는 성형품을 CAE를 통하여 ABS와 PC의 사출조건 냉각시간, 보압의 유/무 등에 따라서 발생되는 문제점과 변형량을 예측하고, 실제 사출성형 되어진 성형품과의 비교 분석을 통하여 사출성형 CAE 해석을 실제 사출성형 공정에서의 활용방안에 대하여 검토하였다.

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3-Phase Inverter Systems using LabVIEW and GPIC (LabVIEW와 GPIC를 이용한 3상 인버터 시스템)

  • Kim, Jae-Woo;Ji, Jun-Keun
    • Proceedings of the KIPE Conference
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    • 2014.07a
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    • pp.544-545
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    • 2014
  • 전력전자와 마이크로프로세서 등 많은 기술들이 포함된 전력전자시스템을 조금이나마 쉽고 빠르게 개발할 수 있도록 NI(National Instrument)사의 LabVIEW를 활용해 C언어나 VHDL의 복잡함을 GUI로 쉽고 빠르게 프로그램하고, GPIC(General Purpose Inverter Controller)를 이용하여 전력전자 시스템 중 3상 인버터를 구동할 수 있음을 보인다.

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Fabriation of Smart Window Using PDLC (PDLC를 이용한 스마트 윈도우 제작)

  • Kang, Mik-Ki;Yun, Tae-Uk;Han, Ga-Ram;Jang, Jae-Hoon;Kim, Chang-Kyo
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2010.06a
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    • pp.158-158
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    • 2010
  • 최근 유리산업은 에너지 절감효과와 친환경 재료의 사용을 바탕으로 하여 기존 유리의 특성을 변화시켜 보다 양질의 재료를 생산해 내고자 한다. 또한 인위적으로 가시광선 전파장에 대한 투과율을 조절할 수 있는 유리 제작의 필요성이 대두되어 스마트 윈도우(smart window)라는 신소재유리가 주목받고 있다. 스마트 윈도우는 태양광의 투과율을 자유롭게 조절할 수 있는 물질을 윈도우에 삽입함으로써 필름을 장착하는 방식에 비하여 태양광의 투과율이 대폭 신장됨과 동시에 사용자에게 고도의 편의성을 제공하는 장점이 있다. 액정과 고분자 매트릭스를 혼합한 PDLC용액을 이용하여 $3{\times}4cm^2$ 크기의 스마트 윈도우를 제작하여 유리 두께, 광량, 스페이서 크기에 따른 투과율을 측정하였다.

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A Case Report of Prescribing Tong shun-san for Three Patients with Compression Fracture (통순산(通順散)을 투여한 압박골절(壓迫骨折)환자 치험 3례)

  • Han, Sang-Wook;Jung, Young-Hun;Kim, Jeong-Won;Kim, Choo-Young;Uhm, Bong-Kun;Lee, Cha-Ro;Lee, Jae-Young
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.6 no.2
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    • pp.145-154
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    • 2011
  • Objectives : The purpose of this study is to investigate the clinical application of Tong shun-san to three patients with compression fracture. Methods : Three patients were hospitalized at Dept. of Oriental Rehabilitation, Bu-Chun Jaseng Oriental Medicine Hospital, diagnosed as compression fracture and treated mainly with herbal medicine ; Tong shun-san. Their conditions were measured by VAS(Visual Analogue Scale) score. Results : After taking Tong shun-san, their pain was reduced. And VAS score was decreased. Conclusions : During three patients with compression fracture were taking Tong shun-san, their conditions were improved.

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The Clinical Observation of 1 Case of Type 1 Complex Regional Pain Syndrome Treated with Korean Medicine Treatment and Harpagophytum radix. Pharmacopuncture (한방치료 및 천수근약침을 병행하여 치료한 제 1형 복합부위통증증후군 환자 치험 1례)

  • Chung, Jai-Hyeon;Yun, Young-Ung;Cheong, Seong-Hyun;Kim, Sin-Woong;Choi, Hee-Seung;Shin, Dong-Jae;Wang, Shann-Jun
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.8 no.1
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    • pp.63-73
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    • 2013
  • Objectives: The purpose of this case is to investigate and report the effectiveness of korean Medicine treatment and Harpagophytum radix. Pharmacopuncture for the type 1 complex regional pain syndrome. Methods: One patient is admitted at Bu-Chun Jaseng Hospital of Korean Medicine, diagnosed as type 1 complex regional pain syndrome and treated with korean Medicine treatment and Harpagophytum radix. pharmacopuncture. This case is measured and assessed by Neumerical Rating Scale(NRS), Oswestry Low-back Pain Disability Index(ODI) and Manual Muscle Test(MMT). Results: After treatment, the intensity and frequency of complex regional pain is gradually decreased and the result of NRS, ODI, MMT showed improvement. Conclusions: As seen in this cases of type 1 complex regional pain syndrome, korean Medicine treatment and Harpagophytum radix. pharmacopuncture appear to be effective for the pain relief and musculoskeletal function recovery.

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Energy Metabolism in Human Pluripotent Stem and Differentiated Cells Compared Using a Seahorse XF96 Extracellular Flux Analyzer

  • Hyun Kyu Kim;Yena Song;Minji Kye;Byeongho Yu;Sang Beom Park;Ji Hyeon Kim;Sung-Hwan Moon;Hyungkyu Choi;Jong-Seok Moon;Jae Sang Oh;Man Ryul Lee
    • International Journal of Stem Cells
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    • v.17 no.2
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    • pp.194-203
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    • 2024
  • Evaluating cell metabolism is crucial during pluripotent stem cell (PSC) differentiation and somatic cell reprogramming as it affects cell fate. As cultured stem cells are heterogeneous, a comparative analysis of relative metabolism using existing metabolic analysis methods is difficult, resulting in inaccuracies. In this study, we measured human PSC basal metabolic levels using a Seahorse analyzer. We used fibroblasts, human induced PSCs, and human embryonic stem cells to monitor changes in basal metabolic levels according to cell number and determine the number of cells suitable for analysis. We evaluated normalization methods using glucose and selected the most suitable for the metabolic analysis of heterogeneous PSCs during the reprogramming stage. The response of fibroblasts to glucose increased with starvation time, with oxygen consumption rate and extracellular acidification rate responding most effectively to glucose 4 hours after starvation and declining after 5 hours of starvation. Fibroblasts and PSCs achieved appropriate responses to glucose without damaging their metabolism 2~4 and 2~3 hours after starvation, respectively. We developed a novel method for comparing basal metabolic rates of fibroblasts and PSCs, focusing on quantitative analysis of glycolysis and oxidative phosphorylation using glucose without enzyme inhibitors. This protocol enables efficient comparison of energy metabolism among cell types, including undifferentiated PSCs, differentiated cells, and cells undergoing cellular reprogramming, and addresses critical issues, such as differences in basal metabolic levels and sensitivity to normalization, providing valuable insights into cellular energetics.