• Clinical and Experimental Reproductive Medicine
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• 제10권1호
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• pp.25-37
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• 1983

A group of 180 men who visited Urology Department of Severance hospital, including 115 patients with nongonococcal urethritis (N.G.U.), 27 patients with prostatitis, 13 patients with gonococcal urethritis (G.U.) and 25 healthy medical student controls were investigated for the isolation of Ureaplasma urealyticum (T-strain mycoplasma) from the specimen of ureaplasma discharge, urine and semen. Taylor-Robinson media of T-broth and T-agar was used for the isolation of Ureaplasma urealyticum. To the best of our knowledge, the study on the culture of Ureaplasma urealy ticum was reported for the first time in Korea. The followis g results were obtained: 1. The isolation rate of Ureaplasma urealyticum in nongonococcal urethritis (53.0%) revealed highest of those in the other three groups of prostatitis, gonococcal urethritis and control (40.7%,38.4% and 16.0% respectively). 2. As for the specimens, urethral discharge revelaed higher isolation rate of Ureaplasma urealyticum (54.6%) than first voided urine (50.0%). 3. The more consorts patients had, the higher positive culture rate of Ureaplasma urealyticum were revealed. The isolation rate in case of more than one causal in nongonococcal urethritis (27.8%) revealed much higher than in case of marital only (5.2%), one regular (6.1%) and one causal 03.9%). 4. 2.6% of isolation rate of Ureaplasma urealyticum revealed in patients with nongonococcal urethritis who visited the clinic in later than 4 weeks after the symptoms developed. However, the isolation rate in patients who visited within 4 weeks revealed 50.3%. The lower isolation rate of Ureaplasma in the late treatment seekers might be probably due to the suppression effect against Ureaplama urealyticum from the possible previous self antibiotic treatment. 5. Attachment of Ureaplasma urealyticum mostly to the neck and head portion of the spermatozoa seemed to playa role to affect the motility of sperms.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제28권4호
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• pp.61-69
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• 2022

Purpose: In response to the rapid spread of COVID-19 in 2020, the government supported facilities and equipment through the 'Urgent Isolation Ward Expansion Project'. Design and remodeling of efficient negative pressure isolation facilities had to be done in a short period of time, and the performance gap between facilities was very large because the types of hospitals and wards of existing medical facilities were diverse. In order to secure the stability of isolation wards between medical facilities and reduce the facility gap, guidelines for planning isolation wards considering the diversity of each hospital should be appropriately presented. In consideration of these points, this study aims to provide basic data for future remodeling guidelines for each plan type of the negative pressure isolation ward first. Methods: We analyzed the plans before and after the change of 13 case hospitals that performed the urgent care bed expansion project for COVID-19 confirmed patients. Before the remodeling, the current status of the facility was analyzed according to the type of corridor, the location of the nursing station, and the location of the elevator. After remodeling, the flow of medical staff and patients, the flow of entry and exit of clean and contaminated items, and the space of negative pressure and non-negative pressure areas. Results: The ward type was divided into three types according to the corridor type and room arrangement: double loaded corridor type with two side wards, race track type with one side ward, and race track type with two side wards. Based on these three types, the standard floor plan type of the isolation ward was proposed in terms of the location of the elevator bank and Nurse station. Implications: When the existing general ward is converted into a negative pressure isolation ward, this study can be a basic data to present customized guidelines for each ward type.

• 중환자간호학회지
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• 제15권2호
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• pp.14-26
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• 2022

Purpose : This study aimed to understand and describe the nurses' experiences caring for severe COVID-19 patients at isolation room with negative pressure in South Korea. Methods : Data were collected through individual in-depth interviews from February 16 to March 31, 2021 with 11 nurses who had been caring for severe COVID-19 patients at isolation room. Verbatim transcripts were analyzed according to Colaizzi's phenomenological analysis. Results : As a result, 5 theme clusters were extracted about nurses' experiences. The 5 theme clusters, "Adapting to unexpected adversity", "Accepting unresonable and heavy work", "Dulness and disconnection from the outside world", "Changing in perception of new infectious diseases", and "Pathetic isolated patients" emerged. Conclusion : The results of this study provided a deeper understanding of nurses struggling to care for COVID-19 severe patients. This study is expected to be useful in providing basic evidence for improving intensive care practices and for preparing policies in other infection disease situations.

• Korean Circulation Journal
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• 제53권5호
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• pp.273-293
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• 2023

Pulsed field ablation (PFA) was recently rediscovered as an emerging treatment modality for the ablation of cardiac arrhythmias. Ultra-short high voltage pulses are leading to irreversible electroporation of cardiac cells subsequently resulting in cell death. Current literature of PFA for pulmonary vein isolation (PVI) consistently reported excellent acute and long-term efficacy along with a very low adverse event rate. The undeniable benefit of the novel ablation technique is that cardiac cells are more susceptible to electrical fields whereas surrounding structures such as the pulmonary veins, the phrenic nerve or the esophagus are not, or if at all, minimally affected, which results in a favorable safety profile that is expected to be superior to the current standard of care without compromising efficacy. Nevertheless, the exact mechanisms of electroporation are not yet entirely understood on a cellular basis and pulsed electrical field protocols of different manufactures are not comparable among one another and require their own validation for each indication. Importantly, randomized controlled trials and comparative data to current standard of care modalities, such as radiofrequency- or cryoballoon ablation, are still missing. This review focuses on the "pearls" and "pitfalls" of PFA, a technology that has the potential to become the future leading energy source for PVI and beyond.

• 대한임상검사과학회지
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• 제40권1호
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• pp.6-17
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• 2008

From the total 116,429 clinical specimens submitted to "C" hospital from January 2005 to December 2006, 2,195 strains of streptococci were isolated. Twenty four species of Streptococcus were identified with 0.1~19.8% isolation frequencies, of which S. pneumoniae was 19.8%, S. agalactiae 16.2%, S. anginosus 9.8%, S. constellatus 5.0%, S. oralis 3.9%, S. mitis 3.3%, S. pyogenes 2.7%, S. salivarius subsp. salivarius 2.2%, S. sanguinis 1.9%. For S. pneumoniae, clinical specimens showing over 9.0% isolation rate were 82.8% in sputum, 9.2% in blood, and for Streptococcus species other than S. pneumoniae, 18.0% in sputum, 16.0% in urine and 9.7% in blood. The antimicrobial agents that showed over 90.0% susceptibility were cefotaxime, gatilfloxacin, imipenem, levofloxacin, linezolid, moxifloxacin, rifampin and sporfloxacin in S. pneumoniae, ampicillin, cefotaxime, cetriaxone, levofloxacin, linezolid, penicillin, quinupristin/dalfopristin and vancomycin in S. agalactiae, chloramphenicol, clindamycin, levofloxacin and vancomycin in S. anginosus, levofloxacin, vancomycin in S. constellatus subsp. constellatus, vancomycin in S. oralis, vancomycin in S. mitis, chloramphenicol, clindamycin, levofloxacin, quinupristin/dalfopristin and vancomycin in S. pyogenes, chloramphenicol, levofloxacin and vancomycin in S. salivarius subsp. salivarius, chloramphenicol, levofloxacin and vancomycin in S. bovis II, chloramphenicol, levofloxacin, quinupristin/dalfopristin and vancomycin in S. dysgalactiae subsp. dysgalactiae, levofloxacin, chloramphenicol and vancomycin in the whole group of 10 Streptococcus spp. other than Streptococcus pneumoniae.

• 국제초고층학회논문집
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• 제12권3호
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• pp.251-262
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• 2023

In response to China's "Regulations on the Management of Earthquake Resistance of Building Constructions" on the provision of eight types of important buildings to maintain functional after fortified earthquakes occur, "Guidelines for Seismic Design of post-quake functional buildings (Draft for Review)" distinguishes Class I and Class II buildings, and gives the performance objectives and seismic verification requirements for design earthquakes and severe earthquakes respectively. In this paper, a hospital and a school building are selected as examples to design according to the requirements of fortification of Intensity 8 and 7 respectively. Two design strategies, the seismic isolation scheme and energy dissipation scheme, are considered which are evaluated through elastic-plastic dynamic time-history analysis to meet the requirement of post-quake functional buildings. The results show that the seismic isolation design can meet the requirements in the above cases, and the energy dissipation scheme is difficult to meet the requirements of the "Guidelines" on floor acceleration in some cases, for which the scheme shall be made valid through the seismic resilience assessment. The research in this paper can provide a reference for designers to choose schemes for post-quake functional buildings.

• 중환자간호학회지
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• 제15권1호
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• pp.35-46
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• 2022

Purpose : This study aimed to identify the factors affecting coronavirus disease 2019 (COVID-19) infection control practices of nurses in negative pressure isolation rooms. Methods : The participants were 150 nurses working in three hospitals with negative pressure isolation rooms. Data were collected using structured questionnaires and analyzed using an independent t-test, one-way ANOVA, Scheffé test, Pearson correlation coefficients, and multiple regression analysis using the SPSS/WIN 26.0 program. Results : Factors significantly influencing the subject's COVID-19 infection control practice include Being married (𝛽=.18, p =.016), working in a ward with negative pressure isolation rooms (𝛽=.44, p <.001), working in an ICU with negative pressure isolation rooms (𝛽=.27, p =.010), COVID-19 infection control attitude (𝛽=.28, p =.001), anxiety for COVID-19 (𝛽=.30, p <.001). The explanatory power of these variables for COVID-19 infection control practice was 24.6% (F=8.67, p <.001). Conclusion : It is expected that strategies that utilize positive attitudes which believe that COVID-19 disease may be overcome by COVID-19 infection control practice will help improve emerging infectious diseases infection control practice.

• 대한미생물학회지
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• 제22권1호
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• pp.9-13
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• 1987

During 31 days (5 week) from December 9th 1985 to January 8th 1986, Influenza B epidemic were observed in Seoul city. Epidemic peak was shown at 52nd week in 1985. The Epidemic associated viruses were determined as B/yamanish/510/84 and B/Ann Arbor/1/86-like strain. From total of 124 specimens of influenza-like illness children virus isolation rate were average 4.0%, much lower than that of influenza A virus isolation experience. In the epidemic influenza B infection were predominantly involved in school age children.

• Journal of Korean Neurosurgical Society
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• 제62권3호
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• pp.336-343
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• 2019

Epilepsy surgery revealed dramatically improved seizure outcomes over medical therapy in drug-resistant epilepsy patients. Children with epilepsy, however, have multiple epileptic focuses which require multilobar resection for better seizure outcome. Multilobar resection has not only the several severe surgical complications, such as hydrocephalus and shunt-related craniosynostosis, due to intracranial volume reduction. Isolation method (disconnection surgery) was progressively studied over epileptic focus removal (resective surgery) for seizure control. This concept was first introduced for functional hemispherotomy, and its primary principle is to preserve the vital vascularized brain that is functionally disconnected from the contralateral healthy brain. Currently in most epilepsy centers, the predominant disconnection surgical methods, including functional hemispherotomy, are continually being refined and are showing excellent results. They allow the functional isolation of the hemisphere or multi-lobe, affected by severe epilepsy. This review describes recent findings concerning the indication, surgical technique, seizure outcome and complications in several disconnection surgeries including the functional hemispherotomy for refractory pediatric epilepsy.

• 성인간호학회지
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• 제14권1호
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• pp.26-33
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• 2002

Purpose: This is a clinical experimental study aimed to provide basic data to ensure quality care. The purpose of this study is to increase nurses hand washing behavior and decrease respiratory isolation rate of MRSA. Method: This study was conducted in Kangnam St. Marys hospital. The subjects included 5 nurses working at the NS ICU and 165 specimen for nasal swabs and 46 specimen for sputum cultures from 106 patients admitted to the NS ICU. The data were collected from June to September 2000. Results: 1.The percentage of the nurses hand washing was 15.6percent but was improved to 46.5 percent after the educational intervention. In particular, hand washing behavior was increased in situations such as after suctioning, before parenteral nutrition, and after providing hygiene care. 2. Results of nasal swab showed that MRSA isolation rate was reduced from 42.8 percent before the education to 18.6percent after the education. The sputum culture results also showed that the MRSA rate was reduced from 40.7percent before the education to 34.6percent after the education. Conclusion: The findings showed the nurses' strict hand washing behavior and use of disposable gloves and paper towers as well as use of hand sterilization spray by visitors or families can decrease the MRSA isolation rate in the NS ICU patients. Since the NS ICU patients may have respiratory complications due to long-term hospitalization, the nurses regular hand washing is important enough to be emphasized. Future research should be focused on the impact of nurses' hand washing behavior on the incidence of pneumonia, an iatrogenic infection.