• 제목/요약/키워드: Intestine, Small

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새끼 하마에서 Clostridium perfringens Type A 감염 증례 (Clostridium perfringens Type A Infection in a Hippopotamus amphibius Cub)

  • 김영섭;임숙경;신남식
    • 한국임상수의학회지
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    • 제25권4호
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    • pp.310-313
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    • 2008
  • C. perfringens is the most important enteric clostridial pathogen of animals. C. perfringens type A has been associated with hemorrhagic enteritis in a wide lange of domestic and wild mammals. But all types of C. perfringens can be normal inhabitants of the intestine of most mammals. We have a special case that showed C. perfringens type A infection in a hippopotamus (Hippopotamus amphibius) cub at Seoul Grand Park Zoo. Male, hippopotamus cub died in 3 days after birth. Clinical features of the hippopotamus cub have showed lethargy and anorexia before death. Gross post-mortem findings of the hippopotamus were hemorrhagic enteritis of intestine. Histopathologically, ruminant stomach and intestine showed hemorrhagic lesions and the lumen of the small intestine was filled with mucoid and hemorrhagic fluid. Also, intestine and stomach of hippopotamus were distended with gas and hemorrhagic fluid. C. perfringens was isolated in culture of small intestine and the presence of C. perfringens type A was confirmed by PCR. This case indicated that C. perfringens type A could be considered as a virulence factor responsible for causing death of a newborn hippopotamus.

캡슐형 내시경 개발을 위한 소장 내에서의 캡슐저항력 특성 (Tribological Characteristics of Endoscope Capsule Inside of Small Intestine)

  • 백남국;김대은
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2002년도 춘계학술대회 논문집
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    • pp.142-145
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    • 2002
  • In order to develop a self-propelled microendoscope, the frictional resistance of the capsule-type endoscope inside the intestine should be understood. In this work the frictional resistance behaviors of capsules with different designs were experimentally investigated using a pig intestine. It was found that cylindrical capsule design had the least frictional resistance. Also, the resistance increased as the speed of the capsule motion was decreased. It is expected that the results of this work will be used to design the optimum propulsion system for the microendoscope.

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말의 그물막구멍포착 교정을 위한 소장 절제 및 문합 1례 (Small Intestine Resection and Anastomosis for Epiploic Foramen Entrapment of a Horse)

  • 황혜신;박철규;황준석;천용우;;이인형
    • 한국임상수의학회지
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    • 제32권4호
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    • pp.374-379
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    • 2015
  • A 10-year-old gelding Warmblood weighing 560 kg was referred to J&C Equine Hospital with the history of hyperpnea, depression, pawing, and rolling for 7 hours. According to the results of clinical and ultrasound examination, it was considered that intestines were distended with thickened wall. The horse had been treated with lactated Ringers' solution (14 L, IV), flunixin meglumine (1.1 mg/kg, IV), and mineral oil (1 L, PO), but he did not show any responses to those treatments. Exploratory laparotomy was performed and identified incarcerated small intestine through the epiploic foramen. The horse received resection and anastomosis of the entrapped small intestine. After surgery, the horse was treated with intensive postoperative care of fluid therapy (5 L with 20 mEq/L KCl, every 2 hours), flunixin meglumine (1.1 mg/kg, IV, sid), antibiotics (penicillin 22,000 IU/kg, IV, qid and gentamicin 6.6 mg/kg, IV, sid), lidocaine constant rate infusion (bolus 1.3 mg/kg over 15 minutes then 0.05 mg/kg/minute), common nutritional supplements, nasogastric intubation every 2 hours and trunk bandage. Postoperative feeding program had started with small amount of hay every 4 hours and gradually increased to normal amount till 5 days. At 77 days after surgery, he showed sudden outbreak of colic and was euthanized. The causes of colic were small intestinal strangulation by passing through the mesenteric rents and postoperative adhesion between small intestines. According to the results, it is recommended to perform perioperative intensive care of horse with colic and to use several methods to prevent adhesions during abdominal surgery of horses.

Effects of Nutritional Level on Digestive Enzyme Activities in the Pancreas and Small Intestine of Calves Slaughtered at Same Body Weight

  • Wang, X.B.;Ogawa, T.;Suda, S.;Taniguchi, K.;Uike, H.;Kumagai, H.;Mitani, K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제11권4호
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    • pp.375-380
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    • 1998
  • Six Holstein heifer calves weaned at 45 days-of-age were randomly allocated into high daily gain (1.1 kg/d, HDG) and low daily gain (0.56 kg/d, LDG) groups, and were slaughtered at 170 kg of live weight. Energy intake level in the feeding period was 2.4 $\times$ maintenance in 105 days for HDG and 1.4 $\times$ maintenance in 216 days for LDG calves. Total length of the small intestine was identical between groups, but both weights of the pancreas and of the small intestinal mucosa were greater (p < 0.01) for HDG calves. Alpha-amylase, lipase, proteinase, and trypsin activities of the whole pancreas were higher (p < 0.05) in HDG calves. Disaccharidase activity of the whole small intestinal mucosa was also higher (p < 0.10) for HDG than for LDG calves. However, the enzymatic activities, expressed as per gram or per protein of the pancreas and the small intestinal mucosa, were not affected (p > 0.10) by the plane of nutrition. These results suggest that the digestive enzyme activity in the small intestine varies primarily with the weight of tissues synthesizing the enzyme.

방사선에 의한 미토콘드리아 손상의 형태학적 고찰 (Morphological Review on Mitochondria Damage by Irradiation)

  • 지태정
    • 대한방사선기술학회지:방사선기술과학
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    • 제43권1호
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    • pp.29-34
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    • 2020
  • Mitochondria was observed much around the nuclear membrane of liver tissue where the energy metabolism process is active. Testis tissue had a large number of undifferentiated cells, and cristae in Inner membrane of Mitochondria was not observed clearly. Morphological damage occurred first in Inner membrane rather than the outer membrane. The kidney tissue was clearly observed in the form of cristae. Radiation-induced damage occurred at the edges of both ends, and the membrane was observed bursting with the thickness of the outer membrane. Small intestine cells were observed in many mitochondria in the tissues around the villus, where bowel movements were active. Morphological damage occurred with the outer and inner membranes getting tangled. Mitochondria sensitivity to radiation was sensitized in testis and small intestine tissues, and kidney, ovary and liver tissues were found to be resistant.

IN VIVO INVESTIGATION ON THE INTESTINAL ABSORPTION OF VITAMIN A-ALCOHOL (RETINOL) IN RATS

  • Whang, Eun-Mi;Burger, Hans-Jurgen
    • 한국영양학회:학술대회논문집
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    • 한국영양학회 1995년도 춘계심포지움 및 학술발표논문 초록
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    • pp.21-21
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    • 1995
  • Absorption of fat-soluble vi tamin, retinol occurs mainly in the proximal part of small intestine. But its intestinal transport mechanism isn't yet clear. The aim of the present study was to investigate on the mechanism of absorption of retinol by determining a concentration-dependent kinetic of retinol absorption in rats. The study was carried out by applying in vivo technique in which vitamin solution was infused to intestinal lumen and at the same time thoracic duct and choledochus duct were canulated to collect samples. The investigations showed that retinol is absorbed in the small intestine by a saturable, carrier-mediated transport system, i.e. wi thout signi ficant differences between the proximal and distal halves of the small intestine. The transport of retinol taken up by the enterocytes occured via different mechanisms: while the main vitamin A transport via the thoracic duct was saturated by limiting transport factors such as retinol-CRBP-II-complex formation and retinol esterification with increasing substrate concentrations, the transport of retinol metabolite product via the portal vein was proportional to the substrate concentration.ration.

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Feline panleukopenia virus infection in imported cats

  • Kang, Sang-Chul;Kang, Kyung-Il;Jean, Young-Hwa;Kim, Jae-Hoon
    • 대한수의학회지
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    • 제47권4호
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    • pp.437-441
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    • 2007
  • The cases of feline panleukopenia virus (FPLV) infection were diagnosed in three imported cats. All cats died within one week after mild emaciation, depression and anorexia. One cat showed yellowish watery diarrhea. At necropsy, all cats had segmental hemorrhage on the serosa and mucosa of the small intestine. Histopathologically, severe diffuse necro-hemorrhagic enteritis was observed in small intestine especially in jejunum and ileum. The crypts of Lieberkuhn were dilated and contained necrotic epithelia. Severely damaged epithelia of crypts were transformed into bizarre shapes. Multifocal lympholysis and lymphoid depletion were found in Peyer's patches and other lymphoid tissues. Direct fluorescent antibody (FA) test revealed the characteristic FPLV antigen in the cytoplasms of crypt epithelial cells. Based on the clinical signs, characteristic pathologic findings and FA test, these cases were diagnosed as FPLV infection. In our best knowledge, this study is the first case report for FPLV infection in imported cats in Korea.

대소장(大小腸) 비별청탁(泌別淸濁)에 관(關)한 고찰(考察) (A Review on Seperation of the Clear[淸] and Turbid[濁] in Large & Small Intestine)

  • 송지청;금경수;엄동명
    • 대한한의학원전학회지
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    • 제23권2호
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    • pp.225-233
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    • 2010
  • Conceptions about functions of large & small intestine[LI & SI] were focused on the vermiculation in "Somun(素問) Yeongranbijeonron(靈蘭秘典論)". However, functions of large & small intestine includes more. In Oriental Medicine, there are sentences in "Hwangjenaegyeong(黃帝內經)" "LI manages Fluid [津] and SI manages Humor[液]" It means that LI & SI have an each role in digestion besides vermiculation. In that reason, we try to find out the meaning of the functions of LI and SI in digestion through bibliographic review. As a result, LI and SI have a digestic function by Separating the Clear which includes Fluids and Humor and the Turbid which is relatively useless to the Clear.

인삼양위탕(人蔘養胃湯)이 위장관(胃腸管)에 미치는 영향(影響) (?Effects of Insamyangwee-Tang on Functions of Stomach and Small Intestine in Experimental Animals)

  • 이동현;김덕곤;정규만
    • 대한한방소아과학회지
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    • 제1권1호
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    • pp.23-37
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    • 1986
  • Although the Insamyangwee-Tang has been widely used in clinical purposes in the oriental medicine and its clinical efficiency is documented for the cases of gastritis, gastric ulcer and enteritis but the experimental study on these has not been undertaken. So,To investigate the clinical efficiency, of Insamyangwee-Tang and validate its oriental medical theory, these experiments were undertaken, by being compared with animal experiment. ?The following results were obtained. ?1. By effect of Insamyangwee-Tang on isolated ileum from mice, rats, rabbits and Guinea pigs, the motility of ileums was inhibited remarkably. ?2. By effect of Insamyangwee-Tang on motility of the small intestine in rabbits, the motility was inhibited remarkably too. ?3. Insamyangwee-Tang inhibited charcoal transport functions in the small intestine of mice. ?4. By effect of Insamyangwee-Tang on isolated duodenum from rats, the motility of duodenum was inhibited remarkably.?5. Gastric juice and pepsin secretion was decreased, anti-ulceration effect was recognized.

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Clostridium perfringens type A associated enteritis in a Shitzu dog

  • Byun, Jae-Won;Yoon, Soon-Seek;Lim, Suk-Kyung;Lee, O-Soo
    • 한국동물위생학회지
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    • 제29권4호
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    • pp.497-501
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    • 2006
  • Acute hemorrhagic enteritis was diagnosed in a seven-month-old male Shitzu dog dying of blood stained diarrhea and vomiting. Clinical findings were anorexia, dullness and sudden death after massive bloody diarrhea. At necropsy, main lesion was the hemorrhage in small intestine, mainly duodenum and jejunum. Microscopically, Gram positive long bacilli were massively detected on the mucose epithelial cells and necrotic debris of small intestine. Coagulative necrosis of epithelial cells and thrombosis of small intestine were also identified. However, there was no lesion of crypt epithelium. Mineral infiltration in both gastric mucosa and renal tubules was detected and proliferation of fibrous tissue was also shown in corticomedullary regions. In bacterial examination, C perfringens was isolated in anaerobic culture and it was confirmed to type A by multiplex PCR. Therefore, the dog was diagnosed as C perfringens type A associated enteritis with uremia.