• Title/Summary/Keyword: Intervention studies

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Surgical Anatomy of Lateral Extracavitary Approach to the Thoracolumar Spine - Cadaveric Study - (흉요추부 외측 강외 접근법(Lateral Extracavitary Approach)의 수술해부학적 구조 - 사체해부실험 -)

  • Kim, Sang-Don;Suh, Jung-Keun;Ha, Sung-Kon;Kim, Joo-Han;Cho, Tae-Hyung;Park, Jung-Yul;Kim, Hyun
    • Journal of Korean Neurosurgical Society
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    • v.30 no.10
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    • pp.1187-1192
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    • 2001
  • Objective : The lateral extracavitary approach(LECA) to the thoracolumbar spine is known as one of procedure which allows not only direct vision of pathologic lesion, but also ventral decompression, and dorsal fixation of the spine through the same incision. However, some drawbacks of LECA, including the technically- demanding, time-consuming, unfamiliar surgical anatomy and excessive blood loss, make surgeons to hesitate to use this approach. This study is to provide the surgical anatomy of LECA using cadavers, for detailed informations when LECA is considered for the surgery. Methods : We performed the 10 cadaveric studies, 7 male and 3 female, and careful dissection was carried out on right side of thoracolumbar region, except one for thoracic region. The photographs with micro-lens were taken to depict the close-up findings and for demonstrating detailed anatomy. Results : The photographs and hand-drawings demonstrated the relationships among the musculature, segmental vessels and nerve roots seen during each dissection plane. The lateral branches of dorsal rami of spinal nerve and the transverse process were confirmed to be the most important landmark of this approach. Conclusion : We concluded that detailed anatomical findings for LECA through this step-by-step dissection would be useful during operative intervention to reduce the intraoperative complications in LECA.

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An Automated Technique for Detecting Axon Structure in Time-Lapse Neural Image Sequence (시간 경과 신경계 영상 시퀀스에서의 축삭돌기 추출 기법)

  • Kim, Nak Hyun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.24 no.3
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    • pp.251-258
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    • 2014
  • The purpose of the neural image analysis is to trace the velocities and the directions of moving mitochondria migrating through axons. This paper proposes an automated technique for detecting axon structure. Previously, the detection process has been carried out using a partially automated technique combined with some human intervention. In our algorithm, a consolidated image is built by taking the maximum intensity value on the all image frames at each pixel Axon detection is performed through vessel enhancement filtering followed by a peak detection procedure. In order to remove errors contained in ridge points, a filtering process is devised using a local reliability measure. Experiments have been performed using real neural image sequences and ground truth data extracted manually. It has been turned out that the proposed algorithm results in high detection rate and precision.

Effectiveness of Individual and Group Counseling for Cessation of Tobacco Habit Amongst Industrial Workers in Pimpri, Pune - An Interventional Study

  • Savant, Suyog Chandrashekhar;Hegde-Shetiya, Sahana;Agarwal, Deepti;Shirhatti, Ravi;Shetty, Deeksha
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.1133-1139
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    • 2013
  • Background: In India, tobacco consumption is responsible for one of the highest rates of oral cancer in the world, the annual oral cancer incidence is steadily increasing among young tobacco users. Studies have documented efforts taken by physicians, doctors and even dentists, in the form of individual or group counseling to curb tobacco use in smoke or smokeless form. However, which one is more effective, still remains an unanswered question. The aim of the study was to compare the effectiveness of individual and group counseling for cessation of the tobacco habit amongst industrial workers in Pune and to compare quit rates. Materials and methods: An interventional study design was selected for 150 industrial workers which were stratified randomly into three groups (control, individual and group counseling groups) and interventions were provided to individual and group counseling groups over a period of six months, which were then compared with the control group that received brief intervention at the start of the study. Results: There was significant difference in the quit rates of the participants in the individual counseling group (ICG) and group counseling group (GCG) when compared at 6 months with the control counseling group (CCG). In the individual counseling group was 6% while in group counseling group it was 7.5% after six months of counseling. Conclusions: No conclusion could be drawn whether individual or group counseling were better interms of quit rates. Individual and group counseling groups were definitely better than the control group when compared at 3 and 6 months, respectively.

Inhibition of Growth and Induction of Differentiation of SMMC-7721 Human Hepatocellular Carcinoma Cells by Oncostatin M

  • Kong, N.;Zhang, X.M.;Wang, H.T.;Mu, X.P.;Han, H.Z.;Yan, W.Q.
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.747-752
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    • 2013
  • Oncostatin M (OSM) is a multifunctional cellular regulator acting on a wide variety of cells, which has potential roles in the regulation of gene activation, cell survival, proliferation and differentiation. Previous studies have shown that OSM can induce morphological and/or functional differentiation and maturation of many tumor cells. However, the action of OSM on the induction of differentiation of human hepatocellular carcinoma (HCC) has not been reported. Here, we investigated the effects of different concentrations of OSM on human HCC cell line SMMC-7721 growth, proliferation, cell cycling, apoptosis and differentiation in vitro. Cell growth was determined via MTT assay, proliferation by cell cycle analysis, apoptosis by flow cytometry, morphology by transmission electronic microscopy, and cell function by detection of biochemical markers. Our results demonstrated that OSM strongly inhibited the growth of SMMC-7721 cells in a dose-dependent manner, associated with decreased clonogenicity. Cell cycle analysis revealed a decreased proportion of cells in S phase, with arrest at G0/G1. The apotosis rate was increased after OSM treatment compared to the control. These changes were associated with striking changes in cellular morphology, toward a more mature hepatic phenotype, accompanied by significant reduction of the expression of AFP and specific activity of ${\gamma}$-GT, with remarkable increase in secretion of albumin and ALP activity. Taken together, our findings indicate that OSM could induce the differentiation and reduce cell viability of SMMC-7721 cells, suggesting that differentiation therapy with OSM offers the opportunity for therapeutic intervention in HCC.

A Validity Study for Linkage of Nursing diagnosis and Nursing Interventions Classification (NANDA간호진단과 간호중재분류(NIC)의 연계에 관한 타당성 연구)

  • Park, Sung-Ae;Park, Jung-Ho;Jung, Myun-Suk;Joo, Mi-Kyoung;Kim, Bog-Ja;Lee, Eun-Suk;Park, Sung-Hee;Yoo, Mi
    • Journal of Korean Academy of Nursing Administration
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    • v.7 no.2
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    • pp.315-347
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    • 2001
  • The purpose of this study was to validate the linkage of nursing diagnosis(NANDA) and Nursing Interventions Classification(NIC) for implementing the Nursing Diagnosis and Nursing interventions in Korea. 36 nurse experts with over the bacculate degree and over 15 years experiences working in tertiary hospitals participated in this study. 5 point Likert scales on each NIC linked 136 NANDA diagnoses were adopted. The results were as follows: 1. In a validity of linkage of nursing diagnosis and nursing interventions classification, the highest score is in 'Chronic low self esteem'(4.66), the lowest score is in 'sensory/Perceptual alterations; Auditory'(3.34) and the average validity score of the total items is 4.27. 2. There was significant differences by educational level and experience in validity score. 3. The nurses who have master degree have higher score than bachelor degree in the diagnoses; 'fatigue', 'health seeking behaviors', 'nutrition: potential for more than body requirements, altered', 'powerlessness'. 4. The nurses with experience over 20 years have higher validity score than less 15 years in 'breast-feeding, effective'. In conclusion, this research indicates that the linkage of NANDA diagnoses and NIC with high validity score can be applied to nursing practice in Korea. And further studies of nursing intervention are needed in Korean culture.

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A Study on the Correlation between Self-efficacy and Self-care in Hemodialysis Patients (혈액투석환자의 자기효능감과 자가간호에 관한 연구)

  • 송미령;김매자;이명은;이인범;서미례
    • Journal of Korean Academy of Nursing
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    • v.29 no.3
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    • pp.563-575
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    • 1999
  • The purpose of this study was to examine the correlation between self-efficacy and self-care of hemodialysis patients. The subjects consisted of 140 hemodialysis patients who underwent hemodialysis at 2 university hospitals. The data were collected by questionnaires and chart review. The questinnaire used the self-efficacy tool developed by Kim Ju Hyune(1995) and the self-care tool developed by literature review and indepth open openended questions to 10 patients. Also, the questionnaire included physiologic data which collected through review of the patients' charts. The statistical analysis was used the SPSS program for frequency, mean, t-test, ANOVA and Pearson correlation. The results were as follows : 1. The mean score for general self-efficacy of hemodialysis patients was 3.103(1-4point) and there were significant differences according to percieved health. The mean score for specific self-efficacy of hemodialysis patients was 3.113 (1-4point) and there were significant differencies according to percieved health, side effects and complications which related hemodialysis. 2. The mean score for self-care of hemodialysis patients was 3.822(1-5point) and there were significant differencies according to marital status and economic level. 3. The relationship between general self-efficacy and self-care was a positive correlation(P=.000). The relationship between specific self-efficacy and self-care was a positive correlation(P=.000). In conclusion, this study revealed the level of self-efficacy and self-care, and the positive correlation between self-efficacy and self-care in hemodialysis patients. Therefore, intervention is needed to promote self-efficacy for self-care of hemodialysis patients. Considering the vulnerable self-care area same as checking blood pressure and weight, fluid restriction, social adjustment, exercise and rest, luther studies should develop self-efficacy promoting programs for self-care of hemodialysis patients.

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Effects of Physical Living Environment on the Social Interaction and Perceived Sense of Community among Students in University Dormitory (대학기숙사 물리적 주거공간환경이 기숙사 거주학생들간 인지된 공동체의식 및 사회적 교류에 미치는 영향 연구)

  • Kim, Won-Pil
    • Journal of the Korean Institute of Educational Facilities
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    • v.22 no.5
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    • pp.3-10
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    • 2015
  • College students living in university dormitory continuously experience unique physical and social living conditions, being away from their hometown and loving families. Most college students has engaged in a very limited social activities in dormitory area. Studies have shown that sense of community(SOC) is closely related to students' social activities. However, few research have examined the relationship between physical environment and sense of community. Therefore, this research aims to evaluate the effects of physical environment of dormitory on students' perceived sense of community and their social interaction. Extensive literature review found that developing social interaction and building a sense of student community improve students' overall residential satisfaction with dormitory and personal academic growth. Survey on A university dormitory and Chi square analysis (${\chi}^2$) indicated that each group's individual characteristics such as gender, grade, living period, and personality were statistically significant on the level of SOC at the level of p=.01. Individual analysis of SOC showed that sense of belonging was higher than shared emotional connection, which means certain level of intervention is needed. Pearson correlation analysis validated that there exists statistically significant relationship between physical environment and SOC. Further it also found that the most important predictor in facilitating social interaction were comfortable, quiet, and enough social space around the dormitory.

The Effect of Children's Temperament, Parenting Behavior and Parenting Stress on Preschool Children's Prosocial Behavior (취학 전 아동의 친사회적 행동에 대한 아동의 기질, 부모의 양육행동 및 양육스트레스의 영향)

  • Kim, Su-Kyoung;Jang, Young-Ae
    • The Korean Journal of Community Living Science
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    • v.21 no.4
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    • pp.605-618
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    • 2010
  • This study was to investigate the effects of children's temperament, parenting behavior, and parenting stress on preschool children's prosocial behavior. The subjects were 190 children consisting of five and six years old and their mothers and fathers. They were selected from 6 kindergartens. Data was collected using the children's prosocial behavior index, the children's temperament index, the parenting behavior questionnaire, and the parenting stress questionnaire. The results were statistically analyzed using t-test, correlation analysis and multiple regression analysis. The study showed that there were some significant differences in children's prosocial behavior according to the children's gender, but there were no significant differences according to the children's age. Correlation analysis indicated that the children's prosocial behavior and children's temperament had significant correlation, especially the children's adaptability and activity indicated high positive correlations. In addition, the children's prosocial behavior and mother's warmth acceptance behavior had significant high positive correlation, and father's rejection restriction behavior had significant high negative correlation. Also, correlation analysis indicated that the children's prosocial behavior and the mother's and father's stress of parent-child dysfunctional interaction and educational distress had significant negative correlations. It was also found that children's gender, mother's permissiveness non- intervention behavior, mother's educational distress, mother's stress of parent-child dysfunctional interaction, and father's stress of parent-child dysfunctional interaction were all significant predictors of the preschool children's prosocial behavior.

The Effectiveness of Na Education Program in Elementary School - Six Month Follow-up Study - (초등학생 Na 교육 효과에 관한 연구 - 사전, 사후, 추후 검증을 통한 교육효과 비교 -)

  • Lee, Young-Mee;Park, Hyun-Nae
    • Korean Journal of Community Nutrition
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    • v.15 no.5
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    • pp.603-613
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    • 2010
  • Nutrition education in elementary school is confronted with the present problem, as a legal basis about obligation of nutrition education in school was clarified. Moreover, it's also important for providing evidence based scientific resources to make a study of evaluating the education effectiveness. Most studies of the nutrition education effectiveness have evaluated the changing dietary attitude and nutritional knowledge score before and after the nutrition education, and suggested the effectiveness of intervention as changing between pre- and post-treatment. Nutrition education, however, purposing long-term changes, follow-up evaluation process about the learned attitude and knowledge of nutrition education were requested. For these reasons, this study attempted to fulfilled standardized nutrition education program which use "Na Story and Food World" and "Na Story for Me", a textbook for the 1st-3rd grade and 4th-6th grade designed by KFDA, and analyzed the changes about the effectiveness of nutrition education happened over a period of time. In this study, each student was assessed their dietary attitude and nutritional knowledge by four periods, before the education, right after the education, after 3 months, and after 6 months. As a result, an average score of nutritional knowledge before the education, $70.08{\pm}17.91$, were changed significantly higher right after the education to $85.69{\pm}15.05$ (p < 0.001), but it lowered to $84{\pm}15.56$ after 3 month. After the nutrition education, students in all grades had positive dietary attitude to Na reduction (p < 0.001). However, the healthy eating attitude about Na reduction had been unable to maintain after 3 and 6 months. Therefore, the systematic reeducated program in elementary school was positively necessary to reinforce children's learning and cognitive skills to maintain healthy eating knowledge and attitude toward Na reduction.

Bio-mechanical Evaluation of Squatting Posture with Asymmetric Trunk Motion (몸통 비틀림 운동을 고려한 쪼그려 앉은 작업자의 요추부 작업부담 평가)

  • Lim, Dae-Seob;Kim, Young-Jin;Lee, Kyoung-Suk;Mun, Joung-Hwan
    • Journal of Biosystems Engineering
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    • v.36 no.1
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    • pp.58-67
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    • 2011
  • A high prevalence of protected horiculture farmer's work-related musculo-skeletal disorders (MSDs) have been reported in precedent studies. One of the tasks required ergonomic intervention to reduce the musculo-skeletal risks is the task of harvesting. The purpose of this study is to evaluate quantitatively the spinal load of worker harvesting with squatting posture to predict and prevent musculo-skeletal risks. Spinal load in Squatting posture with asymmetric trunk motion were analyzed. Before evaluating spinal load on harvesting worker by bio-mechanical approach, it is needed to validate human model. In this study, ADAMS LifeMOD human model shows satisfactory results, comparing with already validated model's results or measured results. While worker reached arms (20%, 40%, 70% arm reach) with various asymmetric trunk motion (0, 45, 90 degree), their spinal loads (extension, twisting and lateral bending moment) were evaluated. In case of extensor moment at lumbo-sacral joint, the more the arm reach got increased, the moment increased. however, in case of twisting moment and lateral bending moment, the more both arm reach and asymmetric trunk motion got increased, the moment increased significantly. The findings of this study suggest that it need to be determine the spinal load, especially twisting, lateral bending moment in evaluating musculo-skeletal workload in squatting posture.