• 대한가정학회지
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• 제44권3호
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• pp.115-126
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• 2006

The purpose of this study was to propose theoretical-practical strategies of family-based intervention for the "Healthy Family-Support Center." The theoretical background used was an ecological approach, that is, taking viewpoints of client family's microsystems as well as those of exo- and macrosystems. This study raised several critical points in researching and developing family-based intervention programs. Based on a review of the literature, the study indicated why an ecological, family-based intervention model was a relevant alternative to investigate issues in family welfare and to deliver possible assistance and solutions for them.

• The Journal of Korean Physical Therapy
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• 제22권2호
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• pp.39-46
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• 2010

Purpose: This study was designed to determine whether General Coordinative Manipulation (GCM) Intervention Models have effects on the balanced restoration of asymmetrical muscles in the extremities. Methods: Fifty-nine healthy subjects (1st hypothesis: n=40, 2nd hypothesis: n=19) participated in studies using the two GCM intervention models. Subjects were studied 2 times a week for 3 weeks. Electromyography (EMG) was used to measure muscle activity, and measurements were performed before and after the application of the each intervention model. Results: Hypothesis 1: GCM Intervention, which coordinates flexion types of muscle contractions of the upper extremity and extension types of muscle contractions of the lower extremity (excluding self-care) is effective for treating shows the treatment in efficiency on more than two 2 of 3 muscles (vastus medialis, gastrocnemius medial, and deltoid middle) and the effects affects on more than 3 types of 4 body types (Vastus medialis, Gastrocnemius medial of Body type III, p<0.05). GCM body type was classified by the relative tilting of right and left scapulars and iliums into four groups. Hypothesis 2: GCM Intervention, which coordinates flexion types of muscle contractions of the lower extremity and extension types of muscle contractions of the upper extremity (excluding self-care) is effective for treating more than two 2 of 3 muscles (vastus medialis, gastrocnemius medial, and deltoid middle) and the effects affects on more than 2 types of 3 body types (p>0.05).

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제21권3호
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• pp.143-154
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• 2017

This paper presents the mathematical model for the MERS-CoV outbreak in South Korea, and the optimal control for two intervention strategies (contact, hospitalization) is implemented. After the MERS-CoV outbreak, hospitalizing infected individuals did not help to prevent the spread of infection. However, the intervention to control contact was effective. It was effective the intervention to controlling both of contact and hospitalization of infection population.

• 재활치료과학
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• 제2권1호
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• pp.87-91
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• 2013

목적 : 본 연구는 첫째, 지역사회 아스퍼거 장애 아동을 대상으로 대처모델(coping model)을 적용한 작업치료 평가를 실시한다. 둘째, 평가결과를 바탕으로 중재계획을 수립해 본다. 연구방법 : 본 연구에 참여한 대상자는 지역사회 아동시설에 거주하는 만 7세 남자 아동이다. 대처모델을 바탕으로 2주간 외적 및 내적 요인으로 나누어 평가를 실시하였다. 외적 요인 평가에는 대상자와 주변환경의 상호작용 및 학교와 지역사회 참여에 대한 내용이 포함되어 있다. 내적 요인 평가는 관찰과 구조화된 평가를 통한 발달 상태와 의학적 상태를 확인하고, 상황에 대한 적절한 기분과 감정 상태에 대한 관찰이 포함되어 있다. 결과 : 대처모델을 적용하여 작업치료 평가가 이루어진 후, 중재 계획을 수립하였다. 첫째, 시간자원을 효과적으로 사용할 수 있도록 한다. 둘째, 지연된 운동 능력을 향상시키기 위해 소운동 영역에 대한 중재 프로그램을 실시한다. 셋째, 아동이 조절하지 못하는 행동들에 대한 자기조절방법과 대처 방법에 대한 교육을 실시한다. 넷째, 시설 내에서 아동에게 지속적으로 관심을 가지고 관리해 줄 수 있는 인적, 물리적 자원에 대해 찾아보고 이를 활용할 수 있도록 한다. 결론 : 본 연구는 지역사회 아스퍼거 아동을 대상으로 대처모델을 적용한 작업치료 평가 및 중재계획을 수립하였다. 향후 연구에서는 직접적인 중재를 통해 실질적인 모델 적용 사례를 제시되어야 할 것이다.

• 대한감각통합치료학회지
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• 제15권2호
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• pp.22-34
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• 2017

목적 : 본 연구의 목적은 우수한 수준으로 감각통합중재를 제공하기 위한 작업치료사 역량모델을 개발하고 개발된 역량모델의 타당성을 검증하는데 있다. 연구방법 : 문헌고찰, 개방형 설문조사, 전문가 포커스 회의를 통해 역량군, 역량, 행동지표의 체계를 가진 감각통합중재를 위한 역량모델 초안을 작성하였고, 2차의 델파이조사와 전문가 자문을 받아 역량모델을 확정하였다. 결과 : 총 4개 역량군, 15개 역량, 60개 행동지표로 구성된 감각통합중재를 위한 작업치료사 역량모델을 개발하였다. '전문성 역량군'에는 5개의 역량(작업치료 일반 지식, 감각통합중재이론 지식, 평가 기술, 분석 기술, 중재 기술)과 31개의 행동지표가 포함되었다. '전문가 의식 역량군'에는 4개의 역량(전문성 고취, 교육, 윤리 의식, 정책적 관심)과 13개의 행동 지표가 포함되었다. '대인 관계 역량군'에는 2개의 역량(의사소통, 협력)과 6개의 행동지표가 포함되었다. 마지막으로 '개인적 특성 역량군'에는 4개의 역량(자기 확신, 자기 성찰, 자기 관리, 긍정적 태도)과 10개의 행동 지표가 포함되었다. 결론 : 본 연구는 작업치료의 한 영역인 감각통합중재를 위한 지식, 기술, 태도를 포함한 역량 모델을 개발하였다는데 의의가 있다. 연구 결과는 향후 대한감각통합치료학회의 역량기반교육과정 개발에 기초 자료로 활용될 수 있을 것이다.

• Biomolecules & Therapeutics
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• 제26권6호
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• pp.539-545
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• 2018

4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1) is a synthetic phthalimide derivative of a marine compound. PD1 has peroxisome proliferator-activated receptor (PPAR) ${\gamma}$ agonistic and anti-inflammatory effects. This study aimed to investigate the effect of PD1 on allergic asthma using rat basophilic leukemia (RBL)-2H3 mast cells and an ovalbumin (OVA)-induced asthma mouse model. In vitro, PD1 suppressed ${\beta}$-hexosaminidase activity in RBL-2H3 cells. In the OVA-induced allergic asthma mouse model, increased inflammatory cells and elevated Th2 and Th1 cytokine levels were observed in bronchoalveolar lavage fluid (BALF) and lung tissue. PD1 administration decreased the numbers of inflammatory cells, especially eosinophils, and reduced the mRNA and protein levels of the Th2 cytokines including interleukin (IL)-4 and IL-13, in BALF and lung tissue. The severity of inflammation and mucin secretion in the lungs of PD1-treated mice was also less. These findings indicate that PD1 could be a potential compound for anti-allergic therapy.

• Journal of Ginseng Research
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• 제42권1호
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• pp.68-74
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• 2018

Background: Ginsenosides have been reported to have many health benefits, including anti-inflammatory effects, and the resolution of inflammation is now considered to be an active process driven by M2-type macrophages. In order to determine whether ginsenosides modulate macrophage phenotypes to reduce inflammation, 11 ginsenosides were studied with respect to macrophage polarization and the resolution of inflammation. Methods: Mouse peritoneal macrophages were polarized into M1 or M2 phenotypes. Reverse transcription-polymerase chain reaction, Western blotting, and measurement of nitric oxide (NO) and prostaglandin $E_2$ levels were performed in vitro and in a zymosan-induced peritonitis C57BL/6 mouse model. Results: Ginsenoside $Rg_3$ was identified as a proresolving ginseng compound based on the induction of M2 macrophage polarization. Ginsenoside $Rg_3$ not only induced the expression of arginase-1 (a representative M2 marker gene), but also suppressed M1 marker genes, such as inducible NO synthase, and NO levels. The proresolving activity of ginsenoside $Rg_3$ was also observed in vivo in a zymosan-induced peritonitis model. Ginsenoside $Rg_3$ accelerated the resolution process when administered at peak inflammatory response into the peritoneal cavity. Conclusion: These results suggest that ginsenoside $Rg_3$ induces the M2 polarization of macrophages and accelerates the resolution of inflammation. This finding opens a new avenue in ginseng pharmacology.

• Journal of Korean Biological Nursing Science
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• 제22권1호
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• pp.1-10
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• 2020

Purpose: Diabetes Mellitus (DM) is a leading cause of death with a prevalence rate of 12.4% in South Korea. Self-management is crucial for patients with DM, because many studies have reported that self-management intervention based on the Health Belief Model (HBM) is effective. The purpose of this study was to investigate the current state of HBM based intervention studies and the components and effects of the theories used in the study for diabetes patients. Methods: A systematic review was conducted using the Pubmed, Cochrane Library and Embase databases from January 2009 to May 2019. We reviewed characteristics of intervention based on the HBM in randomized controlled clinical trials (RCTs), quasi-experimental study intervention. Results: Eight studies published in English between 2009 and 2019 were included in this review. The key components of the health behavior promotion program applied to the DM patients were perceived susceptibility, perceived severity, perceived benefits, perceived barriers and self-efficacy. The intervention based on these components has reported to significantly increase the health behavior change, likelihood of taking health action and improve physiological indicators (HbA1c, and fasting blood sugar etc.). Conclusion: This study highlighted the importance of intervention programs based on the HBM for DM patients.

• 지역사회간호학회지
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• 제32권1호
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• pp.51-63
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• 2021

Purpose: This study aimed to develop an integrated health promotion program for cancer survivors residing in the community based on the shared care model, and evaluate its effectiveness. Methods: A quasi-experimental trial was conducted. The participants consisted of 35 cancer survivors with completed intensive cancer therapy at the cancer hospital. The intervention group (n=20) and the control group (n=15) were recruited from among a district home cancer patient registrations. The intervention group participated in an integrated health promotion program based on the MAPP (Mobilizing for Action through Planning and Partnership) development process. The program consisted of physical, psycho-social and body image units. The participants were assessed before the program, and immediately after the program. Data were collected between July 1 and September 2, 2018 using FACT-G quality of life (QOL), distress thermometer (DT), and resilience. The data were analyzed by performing a χ2 test, Fisher's exact test, Mann-Whitney test, and ranked ANCOVA using SPSS. Results: The intervention group reported a higher QOL overall and significantly higher social/family well-being than the control group. Distress was significantly lower in intervention group than in the control group. Resilience had no significant difference between the two groups. Conclusion: These findings indicate that the integrated health promotion program base on the shared care model and MAPP development process could be effective intervention for improving social/family well-being and the QOL, and reducing distress of cancer survivors at home. Community health center nurses need to provide intervention to support self-care competency for cancer survivors' comprehensive care with physical, psycho-social, and body image to help them adjust their life to a moderate risk group in the community.

• 응용통계연구
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• 제27권3호
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• pp.419-430
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• 2014

전력수급의 정확한 예측은 국민들의 일상적 생활 유지, 산업활동, 그리고 국가경영을 위하여 매우 중요하다. 본 연구에서는 시계열모형화에 의해 전력판매량을 예측한다. 실제 자료분석을 통하여 입력시계열로서 냉난방도일과 개입변수로 펄스함수를 사용한 전이함수모형이 다른 시계열모형에 비해서 제곱근평균제곱오차 및 평균절대오차의 의미에서 더 우수하였다.