• 스마트미디어저널
• /
• 제9권4호
• /
• pp.26-35
• /
• 2020

미래의 주가를 예측하기 위한 시도는 과거부터 꾸준히 연구되어왔다. 그러나 일반적인 시계열 데이터와 달리 금융 시계열 비정상성(non-stationarity)과 장기 의존성(long-term dependency), 비선형성(non-linearity) 등 예측을 하는 것에 있어서 여러 가지 방해 요인이 존재한다. 또한, 광범위한 데이터의 변수는 기존에 사람이 직접 선택하는 것에 한계가 있으며 모델이 변수를 자동으로 잘 추출할 수 있도록 하여야 한다. 본 논문에서는 비정상성 데이터를 정규화할 수 있는 슬라이딩 타임스텝 정규화(sliding time step normalization) 방법과 LSTM 형태의 오토인코더(AutoEncoder)를 사용하여 모든 변수로부터 압축된 변수로 미래 주가를 예측하는 방법, 기간을 나누어 전이 학습을 하는 이동 전이 학습(moving transfer learning)을 제안한다. 또한, 실험을 통하여 100개의 주요 금융 변수들만을 사용하는 것보다 뉴럴 네트워크를 통해서 가능한 많은 변수를 사용하였을 때 성능이 우수함을 보이며, 슬라이딩 타임스텝 정규화 방법을 사용하여 모든 구간에서 데이터의 비정상성에 대해 정규화를 수행함으로써 성능 향상에 효과적임을 보인다. 이동 전이 학습 방법은 스텝 별 테스트 구간에서 모델의 성능을 평가하고 전이학습을 함으로써 긴 테스트 구간에서 성능 향상에 효과적임을 보인다.

• The Korean Journal of Pain
• /
• 제34권1호
• /
• pp.106-113
• /
• 2021

Background: We aimed to investigate the analgesic efficacy of an erector spinae plane block (ESPB) in immediate breast reconstruction (IBR) with a tissue expander. Methods: Adult women undergoing IBR with a tissue expander after mastectomy were randomly assigned to either intravenous patient-controlled analgesia (IV-PCA) alone (group P) or IV-PCA plus ESPB (group E). The primary outcome was the total amount of opioid consumption during 24 hours postoperatively between the two groups. Secondary outcomes were patient satisfaction, pain score at rest and on shoulder movement using numerical rating scale, incidences of postoperative nausea and vomiting (PONV), and a short form of the brief pain inventory (BPI-SF) at 3 and 6 months after surgery between the groups. Results: Fifty eight patients completed the study. At 24 hours postoperatively, total opioid consumption was significantly less in group E than in group P (285.0 ± 92.0, 95% confidence interval [CI]: 250.1 to 320.0 vs. 223.2 ± 83.4, 95% CI: 191.5 to 254.9, P = 0.005). Intraoperative and cumulative PCA fentanyl consumption at 3, 6, 9, and 24 hours were also less in group E than in group P (P = 0.004, P = 0.048, P = 0.020, P = 0.036, and P < 0.001, respectively). Patient satisfaction was higher in group E (6.9 ± 1.8 vs. 7.8 ± 1.4, P = 0.042). The incidences of PONV was similar. Conclusions: The ESPB decreased postoperative opioid consumption and increased patient satisfaction without significant complications after IBR with a tissue expander after mastectomy.

• Journal of Korean Neurosurgical Society
• /
• 제65권2호
• /
• pp.287-296
• /
• 2022

Objective : Although radiotherapy (RT) is recommended for multiple myeloma (MM) involving spine, the treatment of choice between reconstructive surgery with RT and RT alone for pathologic vertebral fractures (PVFs) associated with structural instability or neurologic compromises remains controversial. The purpose of this study was to evaluate the clinical efficacies of reconstructive surgery with adjuvant RT for treatment of MM with PVFs by comparing with matched cohorts treated with RT alone. Methods : Twenty-eight patients underwent reconstructive surgery followed by RT between 2008 and 2015 in a single institution, for management of PVFs associated with structural instability of the spine and/or neurologic compromises (group I). Twenty-eight patients were treated with RT alone (group II) after propensity score matching in a 1-to-1 format based on instability of the spine, as well as age and performance. Clinical outcomes including the overall survival rates, duration of independent ambulation, neurological status, and numeric rating scale (NRS) for back pain were compared. Results : Clinical and radiological features before treatment were similar in both groups. The median survival period was similar between the two groups. However, the mean duration of independent ambulation was significantly longer in group I (88.8 months; 95% confidence interval [CI], 66.0-111.5) than in group II (39.4 months; 95% CI, 25.2-53.6) (log rank test; p=0.022). Deterioration of Frankel grade (21.4% vs. 60.7%, p=0.024) and NRS for back pain (2.7±2.2 vs. 5.0±2.7, p=0.000) at the last follow-up were higher in the group II. Treatment-related complications were similar in both groups. Conclusion : In patients with unstable PVFs due to MM, reconstructive surgery may yield superior clinical outcomes compared with RT alone in maintaining independent ambulation and neurological status, as well as pain control despite similar median survival and complications.

• 생물정신의학
• /
• 제28권1호
• /
• pp.13-22
• /
• 2021

Objectives Despite growing attention to anxiety in bipolar disorder (BD), little research has assessed anxiety symptoms in the course of BD. The current prospective follow-up study examines the influence of subjectively and objectively measured anxiety symptoms on the course of BD. Methods A total of 49 patients with BD were followed-up prospectively for average of one year at an average of four months interval. The Korean version of the Beck Anxiety Inventory (K-BAI), the Hamilton Anxiety Rating Scale, heart rate variability (HRV) were used to measure anxiety subjectively, objectively and physiologically. Participants were divided into high and low anxiety groups based on their K-BAI scores. Kaplan-Meier survival analysis was performed to compare the recurrence of mood episode, suicide attempt, emergency room visit, and psychiatric hospitalization between two groups. Mediators were investigated with Cox proportional hazards models. Results Compared to the low anxiety group, the high anxiety group reported significantly higher impulsiveness (p = 0.016) and lower high frequency component on HRV (p = 0.007) after controlling for severity of BD. Regarding survival analysis, the high anxiety group showed hastened depressive episode recurrence (p = 0.048) and suicidal ideation was the mediator of the hazard ratio (HR) 1.089 (p = 0.029) in the Cox model. Moreover, the high anxiety group showed a tendency of accelerated suicide attempt (p = 0.12) and impulsivity was the risk factor of suicide attempt (HR = 1.089, p = 0.036). Conclusions This interim analysis of prospective study suggests that high anxiety level in BD may anticipate unfavorable course. Further studies are needed to understand the multifactorial mechanism of anxious bipolar patients.

• 한국의료질향상학회지
• /
• 제28권1호
• /
• pp.45-54
• /
• 2022

Purpose: The study aims to identify the theme list and priority criteria of patient safety theme reports in South Korea. Methods: The survey was conducted twice, and the importance of each criterion and theme was measured on a nine-point scale using the Delphi technique by a panel of 19 patient safety experts. The criteria included severity, universality, preventability, and organizational-social impact. Descriptive statistics such as frequency, percentage, mean, standard deviation, median, and interval quartile range were used to analyze the data. Results: The parameters were assigned a weighted average of 35% for severity, 20% for universality, 30% for preventability, and 15% for organizational-social impact, respectively. The final top three rankings were surgery safety, blood transfusion safety, and medication safety. In addition to expert opinion, for the theme that is selected based on the priority ranking, one to five sub-topics can be derived from the theme based on the priority ranking, societal demands, or the yearly priority list of patient safety incidents. Conclusion: It is recommended that the official patient safety center distribute the report in the form of a summary that can be utilized nationwide at medical institutions, government institutions, and other places. Updates, as well as accumulated theme reports, will serve as the baseline data for the proposal of the system and for the policy designed to implement and improve institutions' safety practices as a standard of domestic patient safety practice guidelines.

• 한국구조물진단유지관리공학회 논문집
• /
• 제26권3호
• /
• pp.39-47
• /
• 2022

국내의 공동주택 보급률 증가에 따라 층간소음으로 인한 문제가 증가하고 있다. 이를 예방하기 위하여 바닥 충격음 차단 구조에 대한 수요가 높아지고 있으며 해당 구조에 대한 성능 인증이 이뤄지고 있지만 소음 차단 성능이 현장에서는 재현되지 않는다는 문제점이 있다. 해당 구조가 제 성능을 발휘하기 위해서는 일정 두께 이상의 마감 모르타르 타설이 필요하며, 해당 구조의 시공 적정성 판정을 위하여 GPR을 이용한 두께 측정 실험을 진행하였다. 본 연구에서 개발한 두께 측정 알고리즘은 측정된 데이터를 기반으로 상대유전율을 설정할 수 있어 정확한 두께 값을 측정할 수 있다. 네 종류의 바닥 충격음 차단 인증 구조에서 GPR 두께 측정 실험을 진행하였으며, GPR 데이터와 천공 측정 데이터 간 평균 오차는 1.95mm로 나타났다. 또한 마감재 유무가 측정값에 미치는 영향을 조사하기 위하여 총 3가지 종류의 마감재를 배치하고 실험을 진행으며, 평균 오차는 1.70mm로 나타났다. 추가적으로 장비의 샘플링 오차, 개발 알고리즘 변수, 천공 오차등을 종합적으로 고려하였을 때, GPR 계측 및 제안 알고리즘은 매우 높은 정확도로 슬래브 마감 모르타르의 두께 측정에 적용할 수 있음을 확인하였다.

• Journal of Korean Neurosurgical Society
• /
• 제65권2호
• /
• pp.315-324
• /
• 2022

Objective : The aim of this study was to verify the equivalence and effectiveness of the tablet-administered Korean Repeatable Battery for the Assessment of Neuropsychological Status (K-RBANS) for the prevention and early detection of dementia. Methods : Data from 88 psychiatry and neurology patient samples were examined to evaluate the equivalence between tablet and paper administrations of the K-RBANS using a non-randomly equivalent group design. We calculated the prediction scores of the tablet-administered K-RBANS based on demographics and covariate-test scores for focal tests using norm samples and tested format effects. In addition, we compared the receiver operating characteristic curves to confirm the effectiveness of the K-RBANS for preventing and detecting dementia. Results : In the analysis of raw scores, line orientation showed a significant difference (t=-2.94, p<0.001), and subtests showed small to large effect sizes (0.04-0.86) between paper- and tablet-administered K-RBANS. To investigate the format effect, we compared the predicted scaled scores of the tablet sample to the scaled scores of the norm sample. Consequently, a small effect size (d≤0.20) was observed in most of the subtests, except word list and story recall, which showed a medium effect size (d=0.21), while picture naming and subtests of delayed memory showed significant differences in the one-sample t-test. In addition, the area under the curve of the total scale index (TSI) (0.827; 95% confidence interval, 0.738-0.916) was higher than that of the five indices, ranging from 0.688 to 0.820. The sensitivity and specificity of TSI were 80% and 76%, respectively. Conclusion : The overall results of this study suggest that the tablet-administered K-RBANS showed significant equivalence to the norm sample, although some subtests showed format effects, and it may be used as a valid tool for the brief screening of patients with neuropsychological disorders in Korea.

• 한국전기전자재료학회논문지
• /
• 제35권6호
• /
• pp.631-638
• /
• 2022

Microgrid, which enables the production and consumption of electricity to be done independently on a small scale, has been studied on one of the solutions of reinforcement for flexibility of electronic system. This study examined the application effect of new microgrid by applying hybrid battery in electric power storage device. We designed the system to highlight the advantage of each battery and complement the disadvantage by using hybrid system with Lithium-ion battery and interval Redox flow battery. It runs with lithium-ion battery during the initial startup while the Redox flow battery operates for a long time at the end of excessive period, and it enables a discharge of Lithium-ion and Redox flow battery at the same time when the load has a large output. We chose Maldives as a subject of this study for organizing and optimizing independent microgrid. Maldives is the country to accomplish 100% domestic electricity in South Asia, but the whole electric power is supplied through diesel generation imported fossil fuel. We organized and optimized microgrid for energy independence on Malahini island to solve Maldives energy cost problem and global energy environment matters. We analyzed the daily power supply and accumulated the power supply from September 18, 2018~February 11, 2019. The accumulated power supply was about 120.4 MWh and the daily power supply was about 800~1000 kWh. Based on the collected information, we divided the cases into three models which are only diesel generator, solar generator as well as diesel generator, and solar+ESS+diesel generator. We analyzed the amount of oil consumption compared to the cost of construction and power output. The result showed that solar+ESS+diesel generator was most economically feasible. As well, we obtained that our considering hybrid battery system reduced the fuel consumption for diesel power generation about 10~15%.

• The Korean Journal of Pain
• /
• 제36권1호
• /
• pp.113-127
• /
• 2023

Background: Resting-state functional connectivity (rs-FC) may aid in understanding the link between painmodulating brain regions and the descending pain modulatory system (DPMS) in fibromyalgia (FM). This study investigated whether the differences in rs-FC of the primary somatosensory cortex in responders and non-responders to the conditioned pain modulation test (CPM-test) are related to pain, sleep quality, central sensitization, and the impact of FM on quality of life. Methods: This cross-sectional study included 33 females with FM. rs-FC was assessed by functional magnetic resonance imaging. Change in the numerical pain scale during the CPM-test assessed the DPMS function. Subjects were classified either as non-responders (i.e., DPMS dysfunction, n = 13) or responders (n = 20) to CPM-test. A generalized linear model (GLM) and a receiver operating characteristic (ROC) curve analysis were performed to check the accuracy of the rs-FC to differentiate each group. Results: Non-responders showed a decreased rs-FC between the left somatosensory cortex (S1) and the periaqueductal gray (PAG) (P < 0.001). The GLM analysis revealed that the S1-PAG rs-FC in the left-brain hemisphere was positively correlated with a central sensitization symptom and negatively correlated with sleep quality and pain scores. ROC curve analysis showed that left S1-PAG rs-FC offers a sensitivity and specificity of 85% or higher (area under the curve, 0.78, 95% confidence interval, 0.63-0.94) to discriminate who does/does not respond to the CPM-test. Conclusions: These results support using the rs-FC patterns in the left S1-PAG as a marker for predicting CPM-test response, which may aid in treatment individualization in FM patients.

• 한국지반공학회논문집
• /
• 제25권12호
• /
• pp.5-12
• /
• 2009

록볼트는 터널과 지하공간 구조물의 시공에 있어서 주요 지보재 중 하나이며, 이러한 록볼트의 건전도가 전체 구조물의 안정성에 큰 영향을 미치게 되었다. 본 연구의 목적은 실제 현장에서 투과법을 적용하여 록볼트를 따라 전파되는 유도파를 통해 록볼트의 건전도를 평가하는 것이다. 비파괴 실험의 각기 다른 결함비율을 가진 록볼트 시험체를 제작하여 콘크리트 블록 및 실제현장에 매설한 후, 피에조 디스크 엘리먼트로 유도파를 발생시키고 AE(acoustic emission) 센서를 이용하여 신호를 측정하였다. 수집된 신호는 가버 웨이브렛을 사용한 웨이브렛 변환을 이용하여 시간-주파수 영역에서 분석하였다. 시간-주파수 영역에서의 각 파군별 최대 에너지가 나타나는 지점의 시간차는 각 반사파군 간의 이동 시간차를 나타내며, 이를 통해 계산된 유도파의 에너지 속도는 록볼트의 결함비율이 증가함에 따라 증가하는 것으로 나타났다. 실험에 적합한 양생기간을 제안하였으며 그에 따른 두 번의 현장 실험을 통해 록볼트 건전도 실험의 현장 적용성을 검토하였고, 제안된 실험방법이 록볼트의 건전도 평가에 있어서 유용한 평가방안임을 확인하였다.