• Journal of Korean Neurosurgical Society
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• v.52 no.1
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• pp.7-13
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• 2012

Objective : The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) of fibroblast growth factor (FGF) 2 gene and fibroblast growth factor receptor (FGFR) genes are associated with ossification of the posterior longitudinal ligament (OPLL). Methods : A total of 157 patients with OPLL and 222 controls were recruited for a case control association study investigating the relationship between SNPs of FGF2, FGFR1, FGFR2 and OPLL. To identify the association among polymorphisms of FGF2 gene, FGFR1, FGFR2 genes and OPLL, the authors genotyped 9 SNPs of the genes (FGF2 : rs1476217, rs308395, rs308397, and rs3747676; FGFR1 : rs13317 and rs2467531; FGFR2 : rs755793, rs1047100, and rs3135831) using direct sequencing method. SNPs data were analyzed using the SNPStats, SNPAnalyzer, Haploview, and Helixtree programs. Results : Of the SNPs, a SNP (rs13317) in FGFR1 was significantly associated with the susceptibility of OPLL in the codominant (odds ratio=1.35, 95% confidence interval=1.01-1.81, p=0.048) and recessive model (odds ratio=2.00, 95% confidence interval=1.11-3.59, p=0.020). The analysis adjusted for associated condition showed that the SNP of rs1476217 (p=0.03), rs3747676 (p=0.01) polymorphisms in the FGF2 were associated with diffuse idiopathic skeletal hyperostosis (DISH) and rs1476217 (p=0.01) in the FGF2 was associated with ossification of the ligament flavum (OLF). Conclusion : The results of the present study revealed that an FGFR1 SNP was significantly associated with OPLL and that a SNP in FGF2 was associated with conditions that were comorbid with OPLL (DISH and OLF).

• Journal of Digital Convergence
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• v.16 no.10
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• pp.343-350
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• 2018

The purpose of this study was to identify the effect of nutrition related factors on mortality risk among community-residing older adults in Korea. We analyzed data from 8,532 older adults who took part in the 2008 living profiles of older people survey and 2011 death mortality data. According to Cox regression analysis, male (Hazard Ratio [HR], 2.03; 95% Confidence Interval [CI], 1.74~2.37), diabetes mellitus (HR, 1.35; 95% CI, 1.12~1.64), underweighted (HR, 2.68; 95% CI, 2.16~3.31), dysphagia (HR, 1.23; 95% CI, 1.02~1.47), chewing ability (HR, 1.33; 95% CI, 1.11~1.59), and undernutrition (HR, 1.47; 95% CI, 1.23~1.75) significantly affected mortality risk. Systematic nutrition support programs should be developed to decrease the mortality among Korean older adults.

• Journal of Acupuncture Research
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• v.18 no.5
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• pp.109-121
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• 2001

Objective : The purpose of This study is to analyze influence of functional and clinical improvement effect on temporomandibular disorders of Dong-Qi acupuncture treatment that often be used to temporomandibular disorder patients. Methods : We investigated to focus temporomandibular disorders in Jaseng oriental medicine hospital from September 8, 2000 to March 22, 2001. We compared to before and after treatment situation using temporomandibular disease & facial ache dolor pain and malignant function disorders & activation inhibition analysis from one cured Dong-Qi acupuncture treatment of outpatients-40 examples. Results : These results appeared that Sex distinction occurrence ratio was much more female than male of 1: 7. Age distinction occupied the most ratio in 20-30 generation. Jobs was mainly ranked students and companion. In cases treated before visiting our hospital, was mainly ranked our hospital first dignosis. the distribution interval of solider was mainly followed above 3 years. the distribution interval of treatment was mainly gone within 1 month and above 3 month, frequency of treatment was examined below 5 times, into 6 to 10 times, more than 11 times, respectively. Everything showed a very valuable effect except chewing and dentalgia in decrease of ache dolor pain and linkage pain related to mal-function. There are meaningful effect in Every part on Mal-function improvement. Every contents showed a very excellent effect except activation such as motivation ingestion and recreation in influence of activation. Conclusion : The above results showed a very valuable treatment effect of temporomandibular disorders on Dong-Qi acupuncture treatment. Therefore we are considered the necessity of continuous study and observation applying to other disease as well as temporomandibular disorders.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.52 no.1
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• pp.35-41
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• 2003

In this paper statistics on the radiation field waveforms produced by stepped leaders just prior to lightning return strokes were described. As a parameter of stepped leader pulse characteristics, the time interval between the final leader pulse and return stroke peak, the pause time between stepped leaders, the ratio of the final leader peak to the return stroke peak and the stepped leader pulse width at half maximum were examined. The average time intervals between the final leader pulse and return stroke peak were about 16.2 and 14.8$mutextrm{s}$ for the positive and negative polarities, respectively. When the stepped leader approaches closely to ground, the time interval between leader steps was decreased and the mean value was about 17$mutextrm{s}$, and the present results were in reasonable agreement with the data observed in Florida and Japan. The large fraction of the ratios of the final stepped leader pulse to the lightning return stroke peak were distributed over the range from 5 to 35% and in average the ratio of the final leader pulse to the return stroke peak was 17.4$\pm$11.9% for the positive and 18.5$\pm$9.4% for the negative electric field waveforms. In addition, the mean pulse widths at half maximum of the stepped leaders are 1.4Us with a standard deviation of 0.9 for the positive Polarity and 2.2us with a standard deviation of 1.2 for the negative polarity, respectively.

• Journal of Convergence for Information Technology
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• v.10 no.12
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• pp.31-38
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• 2020

Radar signal identification of electronic warfare is a technology that recognizes the pulse repetition interval (PRI) from a set of pulse description words (PDWs) generated by the signal receiver. Conventionally batch processing is widely used in which a number of PDWs are collected as a unit and identifies PRI from the batch. In this paper, we propose a feature extraction algorithm based on the streaming process. This technique does not wait to form a batch. Whenever a PDW(Pulse Description Word) is generated from the signal receiver, the streaming process tries to form a cluster of PDWs, and makes the DTOA (Difference of Time of Arrival) histogram, finds out the frame PRI based on the concentration ratio, and decides the number of stagger stages. Experiments proved that the proposed algorithm derives stable recognition results as the cluster size increases.

• Women's Health Nursing
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• v.26 no.4
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• pp.300-317
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• 2020

Purpose: Hysteroscopy can be used both to diagnose and to treat intrauterine pathologies. It is well known that hysteroscopy helps to improve reproductive outcomes by treating intrauterine pathologies. However, it is uncertain whether hysteroscopy is helpful in the absence of intrauterine pathologies. This study aimed to confirm whether hysteroscopy improves the reproductive outcomes of infertile women without intrauterine pathologies. Methods: We conducted a systematic review of 11 studies retrieved from Ovid-MEDLINE, Ovid-Embase, and the Cochrane Library. Two independent investigators extracted the data and used risk-of-bias tools (RoB 2.0 and ROBINS-I) to assess their quality. Results: Diagnostic hysteroscopy prior to in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) was associated with a higher clinical pregnancy rate (CPR) and live birth rate (LBR) than non-hysteroscopy in patients with recurrent implantation failure (RIF) (odds ratio, 1.79 and 1.46; 95% confidence interval, 1.40-2.30 and 1.08-1.97 for CPR and LBR, respectively) while hysteroscopy prior to first IVF was ineffective. The overall meta-analysis of LBR showed statistically significant findings for RIF, but a subgroup analysis showed effects only in prospective cohorts (odds ratio, 1.40 and 1.47; 95% confidence interval, 0.62-3.16 and 1.04-2.07 for randomized controlled trials and prospective cohorts, respectively). Therefore, the LBR should be interpreted carefully and further research is needed. Conclusion: Although further research is warranted, hysteroscopy may be considered as a diagnostic and treatment option for infertile women who have experienced RIF regardless of intrauterine pathologies. This finding enables nurses to educate and support infertile women with RIF prior to IVF/ICSI.

• Journal of Korean society of Dental Hygiene
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• v.23 no.2
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• pp.125-132
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• 2023

Objectives: This study used the 2018 Korea Health Panel Survey data to analyze factors affecting employment status and income relating to unmet dental and medical care needs. Additionally it investigated measures to reduce oral health inequality among various socioeconomic classes. Methods: Descriptive statistics for the subjects' unmet dental and medical care needs were calculated through chi-square test analysis, and multivariate logistic regression analysis was applied to identify factors affecting the unmet dental and medical care needs. The odds ratio and 95% confidence interval were calculated for each level. These data were analyzed using STATA 17.0 SE (64-bit) version, and the statistical significance level was set to p<0.05. Results: As a result of unmet dental and medical care needs according to general characteristics, the lower the education level (p<0.001), the higher the age (p<0.001) and the lower the household equalization income (p<0.024) and the smoker status (p<0.003) were, respectively. Factors that have a statistically significant impact on unmet dental and medical care needs were divorce, separation and bereavement (p<0.001) in individuals than in married persons, and being smokers than non-smokers (p<0.009). The frequency of unmet dental and medical care needs were found to be lower in the cases of a high school graduate than an elementary school graduate (p<0.018), and of higher household equalization income (p<0.001) than the lowest household equalization income, respectively. Conclusions: It was found that various factors such as age, education level, household equalization income, employment status, type of working hours type, and smoking status affect unmet dental and medical care needs.

• Animal Bioscience
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• v.36 no.4
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• pp.591-600
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• 2023

Objective: We aimed to evaluate the efficacy of a modified Double-Ovsynch protocol vs artificial insemination following estrus detection (AIED) for the enhancement of reproductive performance in Hanwoo cattle. Methods: Four hundred twelve Hanwoo cows were allocated to two treatment groups. The first group of cows were administered gonadotropin releasing hormone (GnRH) on Day 36 (±0.6), prostaglandin F_2α (PGF_2α) on Day 46 (8 to 12 days later), and GnRH on Day 49, which was followed by Ovsynch, consisting of an injection of GnRH on Day 56, PGF_2α on Day 63, and GnRH 56 h and timed AI (TAI) 16 h later (modified Double-Ovsynch group, n = 203). The second group of cows underwent AIED (AIED group, n = 209) and were designated as controls. Results: The pregnancy per AI 60 days after the first AI was higher in the modified Double-Ovsynch (68.5%) than in the AIED (56.5%) group, resulting in a higher probability of pregnancy per AI (odds ratio: 1.68, p<0.05). Moreover, cows in the modified Double-Ovsynch group were more likely (hazard ratio: 1.28, p<0.05) to be pregnant by 150 days after calving than cows in the AIED group, and this difference was associated with a lower mean number of AIs per conception (1.27 vs 1.39, p<0.05) and a shorter median interval between calving and pregnancy (72 vs 78 days, p<0.1). Conclusion: The modified Double-Ovsynch protocol, adjusted according to the herd visit schedule, can be readily used to increase the pregnancy per AI following the first AI and to shorten the interval between calving and pregnancy in beef herds.

• Tuberculosis and Respiratory Diseases
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• v.86 no.2
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• pp.120-132
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• 2023

Background: To systematically review studies on inhaled corticosteroids (ICS) and lung cancer incidence in chronic airway disease patients. Methods: We conducted electronic bibliographic searches on OVID-MEDLINE, EMBASE, and the Cochrane Database before May 2020 to identify relevant studies. Detailed data on the study population, exposure, and outcome domains were reviewed. Results: Of 4,058 screened publications, 13 eligible studies in adults with chronic obstructive pulmonary disease (COPD) or asthma evaluated lung cancer incidence after ICS exposure. Pooled hazard ratio and odds ratio for developing lung cancer in ICS exposure were 0.81 (95% confidence interval, 0.64 to 1.02; I²=95.7%) from 10 studies and 1.02 (95% confidence interval 0.50 to 2.07; I²=94.7%) from three studies. Meta-regression failed to explain the substantial heterogeneity of pooled estimates. COPD and asthma were variously defined without spirometry in 11 studies. Regarding exposure assessment, three and 10 studies regarded ICS exposure as a time-dependent and fixed variable, respectively. Some studies assessed ICS use for the entire study period, whereas others assessed ICS use for 6 months to 2 years within or before study entry. Smoking was adjusted in four studies, and only four studies introduced 1 to 2 latency years in their main or subgroup analysis. Conclusion: Studies published to date on ICS and lung cancer incidence had heterogeneous study populations, exposures, and outcome assessments, limiting the generation of a pooled conclusion. The beneficial effect of ICS on lung cancer incidence has not yet been established, and understanding the heterogeneities will help future researchers to establish robust evidence on ICS and lung cancer incidence.

• Korean Journal of Optics and Photonics
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• v.34 no.5
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• pp.192-201
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• 2023

The band-limited angular spectrum method (BL-ASM) causes aliasing errors due to spatial frequency control problems. In this paper, a sampling interval adjustment technique for phase holograms and a technique for reducing speckle noise and improving image quality using a deep-learningbased U-net model are proposed. With the proposed technique, speckle noise is reduced by first calculating the sampling factor and controlling the spatial frequency by adjusting the sampling interval so that aliasing errors can be removed in a wide range of propagation. The next step is to improve the quality of the reconstructed image by learning the phase hologram to which the deep learning model is applied. In the S/W simulation of various sample images, it was confirmed that the peak signal-to-noise ratio (PSNR) and structural similarity index measure (SSIM) were improved by 5% and 0.14% on average, compared with the existing BL-ASM.