• 응용통계연구
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• 제16권1호
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• pp.181-193
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• 2003

표본크기를 결정할 때 모표준편차 $\sigma$의 추정량으로 표본표준편차를 구할 수 없는 경우 범위(R)또는 사분위간 범위(IQR)를 이용하여 $\sigma$의 추정량으로 사용할 수 있다 R과 IQR의 함수로 나타난 추정값은 최소한 95% 이상의 확률로 $\sigma$보다 크거나 같아야 과소 추정됨을 피할 수 있다. 다양한 확률분포로부터 추출된 여러 표본의 범위와 사분위간 범위에 대하여 Browne(2001)이 연구한 추정량 R/4과 본 연구에서 제시한 추정량 IQR이 $\sigma$이상일 확률에 대하여 비교 분석을 하였다. 그리고 표본의 범위와 사분위간 범위를 상수로 나누었을 때 $\sigma$이상일 확률을 가질 수 있는 대안적 인 분모를 각각 구하여 비교 연구하였다.

• 한국정보통신학회논문지
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• 제25권10호
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• pp.1296-1301
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• 2021

최근 전 세계적으로 당뇨병 유발률이 증가함에 따라 다양한 머신러닝과 딥러닝 기술을 통해 당뇨병을 예측하려고 는 연구가 이어지고 있다. 본 연구에서는 독일의 Frankfurt Hospital 데이터로 머신러닝 기법을 활용하여 당뇨병을 예측하는 모델을 제시한다. IQR(Interquartile Range) 기법을 이용한 이상치 처리와 피어슨 상관관계 분석을 적용하고 Decision Tree, Random Forest, Knn, SVM, 앙상블 기법인 XGBoost, Voting, Stacking로 모델별 당뇨병 예측 성능을 비교한다. 연구를 진행한 결과 Stacking ensemble 기법의 정확도가 98.75%로 가장 뛰어난 성능을 보였다. 따라서 해당 모델을 이용하여 현대 사회에 만연한 당뇨병을 정확히 예측하고 예방할 수 있다는 점에서 본 연구는 의의가 있다.

• 대한토목학회논문집
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• 제34권5호
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• pp.1455-1461
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• 2014

본 연구에서는 2011년 5월, 6월, 7월에 덕유산 덕곡제에서 관측된 플럭스자료를 이용하여 에디공분산방법으로부터 증발산량을 측정하는 경우 발생할 수 있는 연직방향 풍속의 이상치 판별 및 대체에 대한 통계적 분석을 실시하였다. 연직방향 풍속의 이상치를 파악하기 위해 적용된 통계분석방법은 사분위수를 바탕으로 상자그림(boxplot)의 분석결과 중에 이상치를 판별하기 위한 interquartile range (IQR)을 적용하여 이상치를 탐색하였다. 또한 삭제하거나 평균값으로 대체하는 방법을 통하여 보완된 연직방향 풍속자료를 이용하여 증발산량을 측정하였으며, 이를 보완전의 증발산량과 비교분석하였다. 비교분석한 결과에 의하면 이상치를 대체하기 전의 증발산량과 이상치를 대체한 후의 증발산량 사이에 차이를 보였으며, 특히 강우 시에 보다 큰 차이를 보였다. 따라서 증발산량 측정과정에서 발생하는 이상치를 보완하기 위해 이상치를 삭제하거나 대체하여 증발산량을 측정하는 것이 필요하다.

• Clinics in Shoulder and Elbow
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• 제26권3호
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• pp.222-230
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• 2023

Background: Distal biceps tendon repairs are commonly performed using open techniques. A minimally invasive distal biceps tendon repair technique using a speculum and hooded endoscope was developed to improve visualization, reduce soft-tissue dissection, and minimize complications. This paper describes the technique and reports the outcomes of 75 minimally invasive distal biceps tendon repairs. Methods: The operation reports and outcomes of 75 patients who underwent distal biceps tendon repair using this technique between 2011 and 2021 were retrospectively reviewed. Results: Median time to follow-up was 12 months (interquartile range [IQR], 6-56 months). Primary outcomes were function as measured by the Disabilities of Arm, Shoulder and Hand Score (DASH) questionnaire, and rate of complications. Median DASH score was 1.7 of 100 (IQR, 0-6.8). There were 2 of 75 (2.7%) re-ruptures of the distal tendon. There were no cases of vascular injury, proximal radius fracture, or posterior interosseous nerve, median, or ulnar nerve palsy. Conclusions: In this series, minimally invasive distal biceps repair was safe and effective with a low rate of major complications. Recovery of function, as indicated by low DASH scores, was satisfactory, and inconvenience during recovery was minimized. Level of evidence: IV.

• Journal of the Korean Data and Information Science Society
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• 제23권1호
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• pp.113-120
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• 2012

수시입학이나 면접에서 여러 조가 동시에 면접을 진행하고, 그 점수로 합격을 결정지을 때 면접관에 따른 편차를 조정하기 위한 점수의 표준화는 필수적인 과정이다. 그리고 대부분은 표준편차를 이용하여 표준화를 취한다. 그러나 이 과정에서 자칫 표준편차가 큰 그룹에 속한 후보자는 표준편차가 작은 그룹에 속한 후보자에 비하여 불이익을 당할 우려가 있다. 본 논문에서는 표준편차를 이용한 표준화가 최상의 선택이며, 또한 위험도는 어느 정도 되는지를 알아보기 위하여 다른 표준화 방법과 비교 연구하였다.

• Journal of Chest Surgery
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• 제55권6호
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• pp.452-461
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• 2022

Background: Extracorporeal membrane oxygenation (ECMO) can be used in patients with refractory cardiogenic shock or respiratory failure. In South Korea, the need for transporting ECMO patients is increasing. Nonetheless, information on urgent transportation and its outcomes is scant. Methods: In this retrospective review of 5 years of experience in ECMO transportation at a single center, the clinical outcomes of transported patients were compared with those of in-hospital patients. The effects of transportation and the relationship between insertion-departure time and survival were also analyzed. Results: There were 323 cases of in-hospital ECMO (in-hospital group) and 29 cases transferred to Hallym University Sacred Heart Hospital without adverse events (mobile group). The median transportation time was 95 minutes (interquartile range [IQR], 36.5-119.5 minutes), whereas the median transportation distance was 115 km (IQR, 15-115 km). Transportation itself was not an independent risk factor for 28-day mortality (odds ratio [OR], 0.818; IQR, 0.381-1.755; p=0.605), long-term mortality (OR, 1.099; IQR, 0.680-1.777; p=0.700), and failure of ECMO weaning (OR, 1.003; IQR, 0.467-2.152; p=0.995) or survival to discharge (OR, 0.732; IQR, 0.337-1.586; p=0.429). After adjustment for covariates, no significant difference in the ECMO insertion-departure time was found between the survival and mortality groups (p=0.435). Conclusion: The outcomes of urgent transportation, with active involvement of the ECMO center before ECMO insertion and adherence to the transport protocol, were comparable to those of in-hospital ECMO patients.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권1호
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• pp.26-34
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• 2020

Purpose: To compare the clinical features, diagnostic findings, and medications of children with infrequent bowel movements or fecal soiling. Methods: This study enrolled 333 children (189 male; age range, 1 month to 18 years) diagnosed with functional constipation by Rome III or IV criteria. We classified them into 3 groups (infrequent bowel movement without fecal soiling [G3-a], infrequent bowel movement with fecal soiling [G3-b], and fecal soiling only [G3-c]) and into 2 subgroups of fecal soiling (G2-b) or not (G2-a). Retrospective data on clinical characteristics, colon transit time (CTT) test results, and medications were collected. The Wilcoxon rank-sum test, Kruskal-Wallis test, Chi-square test, and Fisher's exact test were used for the statistical analysis. Results: The median age (months) and interquartile range (IQR) was 33 (45) in G3-a, 54 (40) in G3-b, and 73 (48) in G3-c (p<0.0001). G3-c had the latest onset (median, 18; IQR, 18; p=0.0219) and longest symptom duration (24 [24], p=0.0148). PEG 4000 was used in 60.6% (G3-a), 96.8% (G3-b), and 83.2% (G3-c) of patients (p<0.0001). The median age (months) and IQR were 33.0 (45.0) in G2-a and 63.5 (52.5) in G2-b (p<0.0001). G2-b had later onset (median, 12; IQR, 19.5; p=0.0062) and longer symptom duration than G2-a (24 [12], p=0.0070). PEG 4000 was used in 60.6% (G2-a) and 88.3% (G2-b) of children (p<0.0001). No statistically significant intergroup differences were seen in maintenance laxative dose, CTT, or CTT type. Conclusion: Infrequent bowel movement and fecal soiling represent the advanced stage of chronic functional constipation.

• Clinical and Experimental Reproductive Medicine
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• 제49권2호
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• pp.135-141
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• 2022

Objective: This study investigated the impact of two stimulation protocols using highly purified human menopausal gonadotropin (HP-hMG) on the endocrine profile, follicular fluid soluble Fas levels, and outcomes of intracytoplasmic sperm injection (ICSI) cycles. Methods: This prospective clinical trial included 100 normal-responder women undergoing ovarian stimulation for ICSI; 55 patients received concomitant follicle-stimulating hormone (FSH) plus HP-hMG from the start of stimulation, while 45 patients received FSH followed by HP-hMG during mid/late follicular stimulation. The primary outcome was the number of top-quality embryos. The secondary outcomes were the number and percentage of metaphase II (MII) oocytes and the clinical pregnancy rate. Results: The number of MII oocytes was significantly higher in the concomitant protocol (median, 13.0; interquartile range [IQR], 8.5-18.0 vs. 9.0 [8.0-13.0] in the consecutive protocol; p=0.009); however, the percentage of MII oocytes and the fertilization rate were significantly higher in the consecutive protocol (median, 90.91; IQR, 80.0-100.0 vs. 83.33 [75.0-93.8]; p=0.034 and median, 86.67; IQR, 76.9-100.0 vs. 77.78 [66.7-89.9]; p=0.028, respectively). No significant between-group differences were found in top-quality embryos (p=0.693) or the clinical pregnancy rate (65.9% vs. 61.8% in the consecutive vs. concomitant protocol, respectively). The median follicular fluid soluble Fas antigen level was significantly higher in the concomitant protocol (9,731.0 pg/mL; IQR, 6,004.5-10,807.6 vs. 6,350.2 pg/mL; IQR, 4,382.4-9,418.4; p=0.021). Conclusion: Personalized controlled ovarian stimulation using HP-hMG during the late follicular phase led to a significantly lower response, but did not affect the quality of ICSI.

• Journal of Chest Surgery
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• 제56권6호
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• pp.414-419
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• 2023

Background: The recurrence of ventricular arrhythmias (VAs) in patients who have already undergone treatment with antiarrhythmic medication, catheter ablation, and the insertion of implantable cardioverter defibrillators is not uncommon. Recent studies have shown that bilateral cardiac sympathetic denervation (BCSD) effectively treats VAs. However, only a limited number of studies have confirmed the safety of BCSD as a viable therapeutic option for VAs. Methods: This single-center study included 10 patients, who had a median age of 54 years (interquartile range [IQR], 45-65 years) and a median ejection fraction of 58.5% (IQR, 56.2%-60.8%), with VAs who underwent video-assisted BCSD. BCSD was executed as a single-stage surgery for 8 patients, while the remaining 2 patients initially underwent left cardiac sympathetic denervation followed by right cardiac sympathetic denervation. We evaluated postoperative complications, the duration of hospital stays, and VA-related symptoms before and after surgery. Results: The median hospital stay after surgery was 2 days (IQR, 2-3 days). The median surgical time for BCSD was 113 minutes (IQR, 104-126 minutes). No significant complications occurred during hospitalization or after discharge. During the median follow-up period of 13.5 months (IQR, 10.5-28.0 months) from surgery, no VA-related symptoms were observed in 70% of patients. Conclusion: The benefits of a short postoperative hospitalization and negligible complications make BCSD a safe, alternative therapeutic option for patients suffering from refractory VAs.

• 환경영향평가
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• 제26권6호
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• pp.524-537
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• 2017

사후환경영향조사 결과의 신뢰도 제고에 대한 문제가 대두되어 왔으나 조사결과에 대한 객관적인 검증을 수행한 연구가 미흡한 실정이다. 본 연구에서는 개발 사업에 의한 수질영향을 조사하였고 그 결과를 바탕으로 사후환경영향조사 시 수질분야에 결과와 비교 분석을 수행하였다. 토석채취사업장 내 오수처리시설 최종방류수에 Biochemical oxygen demand(BOD), Suspended solid(SS), Total nitrogen(T-N), Total phosphorus(T-P) 농도가 높게 나타났다. 사후환경영향조사 결과와 비교한 결과, 오수처리시설 최종방류수의 BOD, SS, T-N, T-P 농도가 사후환경영향조사 시 분기별 농도의 사분범위(Interquartile range, IQR)와 최소값과 최대값의 농도범위보다 높게 나타났다(p<0.05). 체육시설(훈련원) 조성사업의 경우에는 오수처리시설 최종방류수에 BOD, SS, T-N, T-P가 높은 농도로 검출되었고 BOD와 SS 농도는 협의기준을 초과하였다. BOD와 SS 농도는 사후환경영향조사 시 오수처리시설 최종방류수의 농도와 유의한 차이를 나타냈다(p<0.05). 이러한 연구결과, 개발 사업 시 오수처리시설 최종방류수에 대한 체계적인 수질 모니터링과 적절한 수질관리가 수행되어야 할 것이다. 또한 사후환경영향조사결과의 신뢰도 제고를 위한 방안이 모색되어야 할 것이다.