• 제목/요약/키워드: Interquartile range

검색결과 203건 처리시간 0.028초

Diagnostic value of Thyroglobulin Measurement with Fine-needle Aspiration Biopsy for Lymph Node Metastases in Patients with a History of Differentiated Thyroid Cancer

  • Zhang, Hai-Shan;Wang, Ren-Jie;Fu, Qing-Feng;Gao, Shi;Sun, Bu-Tong;Sun, Hui;Ma, Qing-Jie
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권24호
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    • pp.10905-10909
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    • 2015
  • Purpose: The aim of this study was to evaluate the diagnostic value of FNA-Tg for detecting lymph node metastases in patients with a history of differentiated thyroid cancer (DTC). Materials and Methods: A total of 58 patients with DTC diagnosis and evidence of single or multiple suspicious cervical lymph nodes were assessed. All underwent total or near-total thyroidectomy with (35 cases) or without (23 cases) radioiodine (RAI) ablation, followed by thyroid stimulating hormone (TSH) suppression therapy. A total of 68 lymph nodes were examined by ultrasound-guided fine needle aspiration (US-FNA) for both cytological examination and FNA-Tg measurement. Serum Tg and anti-thyroglobulin antibody (TgAb) levels were also measured. Diagnostic performance including sensitivity, specificity, accuracy, positive (PPV) and negative predictive value (NPV) of FNAC and FNA-Tg were calculated and compared. The Spearman's rank correlation coefficient was used to estimate the relationship between FNA-Tg and serum TgAb. Results: The FNA-Tg levels were significantly higher with DTC metastatic lymph nodes (median 927.7 ng/mL, interquartile range 602.9 ng/mL) than non-metastatic lymph nodes (median 0.1 ng/mL, interquartile range 0.4 ng/mL) (p<0.01). Considering 1.0 ng/mL as a threshold value for FNA-Tg, the sensitivity, specificity, accuracy, PPV and NPV of FNA-Tg were 95.7%, 95.5%, 95.6%, 97.8% and 91.3%, respectively. The sensitivity and accuracy of the combination of FNAC and FNA-Tg were significantly higher than that of FNAC alone (p<0.05). The diagnostic performance of FNA-Tg was not significantly different between cases with or without RAI ablation, and the serum TgAb levels did not interfere with FNA-Tg measurements. Conclusions: Measurement of FNA-Tg is useful. The combination of FNAC and FNA-Tg is more sensitive and accurate for detecting lymph node metastases in patients with a history of DTC than FNAC alone. Serum TgAbs appear to be irrelevant for measurement of FNA-Tg.

중학교 통계영역의 교육과정 개선을 위한 외국 교육과정의 탐색: 한국, 미국, 싱가포르, 일본의 학습 요소 중심으로 (Exploration of Foreign Curriculums for the Improvement of the Korean Middle School Statistical Curriculum: Focusing on learning elements in Korea, the United States, Singapore, and Japan)

  • 김소민
    • 한국학교수학회논문집
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    • 제22권4호
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    • pp.501-520
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    • 2019
  • 본 연구의 목적은 한국, 미국, 싱가포르, 일본의 중학교 수학과 교육과정의 통계영역의 성취기준과 학습 요소를 중심으로 비교·분석하여 우리나라의 중학교 통계영역의 교육과정의 개선 방향에 대한 시사점을 얻기 위함이다. 교육과정 비교·분석 결과, 전반적인 성취기준과 학습 요소에 대한 특징과 차이점을 발견하였다. 첫째, 한국, 미국, 싱가포르, 일본 네 나라 모두 실생활 맥락에서의 통계교육을 강조하였다. 둘째, 네 나라 모두 공학적 도구의 활용을 강조하였다. 셋째, 우리나라만 통계영역을 다루지 않는 학년이 있다. 넷째, 미국, 싱가포르, 일본의 통계영역은 자료 분포의 경향을 파악하는데 중점을 두었다. 다섯째, 미국, 싱가포르, 일본에서는 다루지만 우리나라에서는 다루지 않는 학습 요소를 몇 가지 찾을 수 있었다. 이를 바탕으로 우리나라의 차기 교육과정 개발과 새로운 교과서 개발을 위한 시사점을 도출하였다. 첫째, 통계적 개념의 이해 위주에서 이를 활용한 통계적 활동 중심의 교육과정이 되어야 한다. 둘째, 중학교 통계영역 교육과정의 학습 요소 개선 측면에서, 사분위범위와 상자 그림을 학습 요소로 추가하는 것을 고려할 필요가 있다. 사분위범위와 상자 그림은 자료 분석 영역에서 복수의 집단 간의 비교를 위한 간단하고 실용적인 기법으로, 중학생 수준의 학생들이 간단히 배워서 쉽게 그릴 수 있고, 실생활 관련 통계적 자료에 적용하면서 통계적 소양을 확충할 수 있다. 본 연구를 통해 사분위범위와 상자 그림이 우리나라 중학교 통계영역 교육과정에도 새롭게 추가 선정될 필요가 있음을 제안한다.

통계분석 알고리즘 프로그램을 활용한 동시 인상 3D 콘크리트 프린팅의 성능 분석 (Performance Analysis of Simultaneous Liftable 3D Concrete Printing Based on Statistical Analysis Algorithm)

  • 김윤철;김성조;김봉식;지용수;한동석
    • 한국전산구조공학회논문집
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    • 제36권6호
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    • pp.407-414
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    • 2023
  • 본 논문에서는 다양한 분야에 적용할 수 있는 자동화 동시 인상 시스템을 3D 콘크리트 프린팅에 적용하여 동시 인상이 가능한 3D 콘크리트 프린팅 시스템으로 개발하였다. 개발된 시스템은 3D 콘크리트 프린팅 작업 중 측정되는 인상량을 피어슨 상관계수를 통해 분석하고, 유압시스템을 사분위수 기법으로 실시간 모니터링하여 안전하고 정밀한 인상이 가능하다. 이를 활용하면 3D 콘크리트 프린팅 구조물의 출력 품질을 확보함과 동시에 3D 콘크리트 프린팅의 규모보다 큰 구조물을 출력할 수 있다. 시스템의 성능을 평가하기 위해 기존의 3D 콘크리트 프린팅과 동시 인상이 가능한 3D 콘크리트 프린팅을 각각 이용하여 시편을 출력하였다. 출력된 시편은 3D 스캐너를 활용하여 측정하였다. 스캔한 시편의 층별 직경과 시편의 교차각을 측정하였으며, 분석을 통해 동시 인상이 가능한 3D 콘크리트 프린팅의 성능을 검증하였다.

Effect of Stent Placement on Survival in Patients with Malignant Portal Vein Stenosis: A Propensity Score-Matched Study

  • Dong Jae Shim;Jong Woo Kim;Doyoung Kim;Gi-Young Ko;Dong Il Gwon;Ji Hoon Shin;Yun-Jung Yang
    • Korean Journal of Radiology
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    • 제23권1호
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    • pp.68-76
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    • 2022
  • Objective: Percutaneous portal vein (PV) stent placement can be an effective treatment for symptoms associated with portal hypertension. This study aimed to evaluate the effect of PV stenting on the overall survival (OS) in patients with malignant PV stenosis. Materials and Methods: Two groups of patients with malignant PV stenosis were compared in this retrospective study involving two institutions. A total of 197 patients who underwent PV stenting between November 2016 and August 2019 were established as the stent group, whereas 29 patients with PV stenosis who were treated conservatively between July 2013 and October 2016 constituted the no-stent group. OS was compared between the two groups before and after propensity score matching (PSM). Risk factors associated with OS were evaluated using the Cox proportional hazards model. Procedure-associated adverse events were also evaluated. Results: The stent group finally included 100 patients (median age, 65 [interquartile range, 58-71] years; 64 male). The no-stent group included 22 patients (69 [61-75] years, 13 male). Stent placement was successful in 95% of attempted cases, and the 1- and 2-year stent occlusion-free survival rate was 56% (95% confidence interval, 45%-69%) and 44% (32%-60%), respectively. The median stent occlusion-free survival time was 176 (interquartile range, 70-440) days. OS was significantly longer in the stent group than in the no-stent group (median 294 vs. 87 days, p < 0.001 before PSM, p = 0.011 after PSM). The 1- and 3-year OS rates before PSM were 40% and 11%, respectively, in the stent group. The 1-year OS rate after PSM was 32% and 5% in the stent and no-stent groups, respectively. Anemia requiring transfusion (n = 2) and acute thrombosis necessitating re-stenting (n = 1) occurred in three patients in the stent group within 1 week. Conclusion: Percutaneous placement of a PV stent may be effective in improving OS in patients with malignant PV stenosis.

Prognostic Implication of Right Ventricle Parameters Measured on Preoperative Cardiac MRI in Patients with Functional Tricuspid Regurgitation

  • Yura Ahn;Hyun Jung Koo;Joon-Won Kang;Won Jin Choi;Dae-Hee Kim;Jong-Min Song;Duk-Hyun Kang;Jae-Kwan Song;Joon Bum Kim;Sung-Ho Jung;Suk Jung Choo;Cheol Hyun Chung;Jae Won Lee;Dong Hyun Yang
    • Korean Journal of Radiology
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    • 제22권8호
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    • pp.1253-1265
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    • 2021
  • Objective: To investigate the prognostic value of preoperative cardiac magnetic resonance imaging (MRI) for long-term major adverse cardiac and cerebrovascular events (MACCEs) in patients undergoing tricuspid valve (TV) surgery for functional tricuspid regurgitation (TR). Materials and Methods: The preoperative cardiac MR images, New York Heart Association functional class, comorbidities, and clinical events of 78 patients (median [interquartile range], 59 [51-66.3] years, 28.2% male) who underwent TV surgery for functional TR were comprehensively reviewed. Cox proportional hazards analyses were performed to assess the associations of clinical and imaging parameters with MACCEs and all-cause mortality. Results: For the median follow-up duration of 5.4 years (interquartile range, 1.2-6.6), MACCEs and all-cause mortality were 51.3% and 23.1%, respectively. The right ventricular (RV) end-systolic volume index (ESVI) and the systolic RV mass index (RVMI) were higher in patients with MACCEs than those without them (77 vs. 68 mL/m2, p = 0.048; 23.5 vs. 18.0%, p = 0.011, respectively). A high RV ESVI was associated with all-cause mortality (hazard ratio [HR] per value of 10 higher ESVI = 1.10, p = 0.03). A high RVMI was also associated with all-cause mortality (HR per increase of 5 mL/m2 RVMI = 1.75, p < 0.001). After adjusting for age and sex, only RVMI remained a significant predictor of MACCEs and all-cause mortality (p < 0.05 for both). After adjusting for multiple clinical variables, RVMI remained significantly associated with all-cause mortality (p = 0.005). Conclusion: RVMI measured on preoperative cardiac MRI was an independent predictor of long-term outcomes in patients who underwent TV surgery for functional TR.

Short-term comparative outcomes between reverse shoulder arthroplasty for shoulder trauma and shoulder arthritis: a Southeast Asian experience

  • Ng, Julia Poh Hwee;Tham, Sherlyn Yen Yu;Kolla, Saketh;Kwan, Yiu Hin;Tan, James Chung Hui;Teo, Timothy Wei Wen;Wee, Andy Teck Huat;Toon, Dong Hao
    • Clinics in Shoulder and Elbow
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    • 제25권3호
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    • pp.210-216
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    • 2022
  • Background: Reverse shoulder arthroplasty (RSA), first introduced as a management option for cuff tear arthropathy, is now an accepted treatment for complex proximal humeral fractures. Few studies have identified whether the outcomes of RSA for shoulder trauma are comparable to those of RSA for shoulder arthritis. Methods: This is a retrospective, single-institution cohort study of all patients who underwent RSA at our institution between January 2013 and December 2019. In total, 49 patients met the inclusion criteria. As outcomes, we evaluated the 1-year American Shoulder and Elbow Surgeons (ASES) and Constant shoulder scores, postoperative shoulder range of motion, intra- and postoperative complications, and cumulative revision rate. The patients were grouped based on preoperative diagnosis to compare postoperative outcomes across two broad groups. Results: The median follow-up period was 32.8 months (interquartile range, 12.6-66.6 months). The 1-year visual analog scale, range of motion, and Constant and ASES functional scores were comparable between RSAs performed to treat shoulder trauma and that performed for arthritis. The overall complication rate was 20.4%, with patients with a preoperative diagnosis of arthritis having significantly more complications than those with a preoperative diagnosis of trauma (34.8% vs. 7.7%). Conclusions: Patients who underwent RSA due to a proximal humeral fracture or dislocation did not fare worse than those who underwent RSA for arthritis at 1 year, in terms of both functional and radiological outcomes.

Short-term Associations of Air Pollution with Postneonatal Infant Death in Seoul, Korea, 1999-2003

  • Lee, Jong-Tae;Cho, Yong-Sung;Son, Ji-Young
    • 한국환경보건학회지
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    • 제34권5호
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    • pp.361-368
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    • 2008
  • Objective to assess whether exposure to air pollutants is associated with postneonatal infant death, using a timeseries methodology, between 1999 and 2003 in Seoul, Korea.. Methods We investigated the short-term effects of air pollution for 548,725 live births during the study period. The daily count of postneonatal infant deaths from all causes and from SIDS (sudden infant death syndrome) by birth order was analyzed by a Generalized Additive Poisson model, with controlling for the effects of seasonal trends, air temperature, relative humidity, barometric pressure, and day of the week as covariates. Results During the study period, we observed 699 deaths from all causes and 47 deaths from SIDS. We did not find any significant associations between daily mortality and ambient levels of air pollutants except for CO and $NO_2$. The estimated relative risk of postneonatal infant death from all causes was 1.17 (95% CI=1.04-1.32) and 1.16 (95% CI=1.03-1.29) by IQR (interquartile range) for CO and $NO_2$ respectively. Also, we observed no clear trend of the mortality effects of air pollution by birth orders. Conclusion In conclusion, our findings suggest that air pollution, in general, influenced adversely postneonatal infant death from all-cause and SIDS although it was not statistically significant. This study may support that the rationale.

20대 여성의 표준체형과 인대 적합성에 관한 연구 (Standardized Body Type and the Suitability of Figures for the Twenties Women)

  • 구미지;이정임
    • 한국의류산업학회지
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    • 제7권6호
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    • pp.601-608
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    • 2005
  • This research investigated the present state of the dress forms used by clothing manufacturers and proposed procedure to bring out the standardized body type and figure for women in twenties. The result of questionnaire showed chief pattern maker's thoughts that dress form should be differently made for each age group and should be more reflected the standard body than the idea body. The standardized body type was made from the standardized posture and size which were analyzed from the interquartile range(IQR) of 314 subjects. The standardized size could be verified as for the balanced body shape of twenties through making the standard dress form. The standardized form(S form) was compared with three kinds of forms(A, K and P) for investigating the suitability of forms. K form was very similar to S form, Educational P form and manufacturer's A form had quite big differences from S form at the important areas for making clothing. The side shapes of A, K and P forms showed differences at back bending, neck angle and hip shape from S form. A form was comparatively smooth and flat. This results could be used as the practical standard to improve the suitability of size and shape in the dress forms of manufacturers and educators.

파노라마방사선사진을 이용한 경상돌기에 관한 연구 (A study on the styloid process in panoramic radiographs)

  • 황지영;황의환;이상래
    • Imaging Science in Dentistry
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    • 제35권2호
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    • pp.105-110
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    • 2005
  • Purpose : To find statistically based information about the natural variation in the length of the styloid process and to show the influence of the gender and age on the length of the styloid process. Materials and Methods : 1,300 panoramic radiographs were retrieved from inactive files at the Dental Hospital of Kyung Hee University. Measurements of the length of the styloid process were made directly on the radiographs from the inferior margin of the tympanic plate to the tip of the styloid process. Results The mean length of 948 styloid processes was $25.2mm{\pm}6.6$. The median was 24.5 mm, and the interquartile range was 7 mm. The mean length was 25.7 mm for male and 24.6 mm for female. All percentile was greater for male than for female. The median is 25 mm for male and 24 mm for female. Conclusion : This study suggests that the difference of the styloid process length between genders was statistically significant and the length of styloid process was significant increased with age until 30 years.

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농촌유역 홍수관리를 위한 자료처리 요소모듈 개발 (Development of data processing component module for the flood management in an agricultural watershed)

  • 이도길;강문성;박지훈;류정훈
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2016년도 학술발표회
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    • pp.289-289
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    • 2016
  • 신뢰성 높은 홍수관리는 경향성 분석, 이상치 판정 등의 전처리를 수행한 입력 자료를 구축하는 것을 필요로 한다. 경향성 분석은 방법에 따라 경향성의 유무가 다르게 나타나기 때문에 하나의 방법으로만 판단하기 어려우며, 이상치 분석은 지역 특성에 따라 기준이 변동하므로 일정한 기준을 적용하기가 어려워 주로 수동으로 이루어지며 이 작업을 완료하는 데에는 많은 시간이 소요된다. 입력 자료 전처리에 수반되는 비용과 시간을 절감하기 위해 이러한 문제점의 개선이 필요한 실정이다. 따라서 본 연구의 목적은 농촌유역 홍수관리를 위한 자료처리 요소 모듈을 개발하는 데 있다. 홍수관리를 위한 자료처리 요소 모듈은 크게 기상자료의 경향성을 분석하는 모듈과 수위자료의 이상치를 탐지하고 판정하는 모듈로 구성하였다. 경향성 분석 모듈은 모수적 방법인 t-test와 비모수적 방법인 Hotelling-Pabst test 및 Mann-Kendall test를 분석 방법으로 제공하여 하나의 입력 자료로 세 가지 방법으로 분석한 결과를 비교할 수 있도록 개발하였다. 이상치 탐지 모듈은 IQR (interquartile range) 규칙과 규칙기반의 방법을 이용한 이상치 탐지를 제공할 수 있도록 개발하였다. 개발된 모듈은 한강 유역의 용당저수지에 적용하여 검정을 실시하였다. 본 연구에서 개발된 농촌유역 홍수관리를 위한 자료처리 요소 모듈은 추후 홍수관리 및 그에 관한 연구를 하는데 있어 활용될 수 있을 것으로 기대된다.

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