• Title/Summary/Keyword: Interquartile range

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Diagnostic value of Thyroglobulin Measurement with Fine-needle Aspiration Biopsy for Lymph Node Metastases in Patients with a History of Differentiated Thyroid Cancer

  • Zhang, Hai-Shan;Wang, Ren-Jie;Fu, Qing-Feng;Gao, Shi;Sun, Bu-Tong;Sun, Hui;Ma, Qing-Jie
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10905-10909
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    • 2015
  • Purpose: The aim of this study was to evaluate the diagnostic value of FNA-Tg for detecting lymph node metastases in patients with a history of differentiated thyroid cancer (DTC). Materials and Methods: A total of 58 patients with DTC diagnosis and evidence of single or multiple suspicious cervical lymph nodes were assessed. All underwent total or near-total thyroidectomy with (35 cases) or without (23 cases) radioiodine (RAI) ablation, followed by thyroid stimulating hormone (TSH) suppression therapy. A total of 68 lymph nodes were examined by ultrasound-guided fine needle aspiration (US-FNA) for both cytological examination and FNA-Tg measurement. Serum Tg and anti-thyroglobulin antibody (TgAb) levels were also measured. Diagnostic performance including sensitivity, specificity, accuracy, positive (PPV) and negative predictive value (NPV) of FNAC and FNA-Tg were calculated and compared. The Spearman's rank correlation coefficient was used to estimate the relationship between FNA-Tg and serum TgAb. Results: The FNA-Tg levels were significantly higher with DTC metastatic lymph nodes (median 927.7 ng/mL, interquartile range 602.9 ng/mL) than non-metastatic lymph nodes (median 0.1 ng/mL, interquartile range 0.4 ng/mL) (p<0.01). Considering 1.0 ng/mL as a threshold value for FNA-Tg, the sensitivity, specificity, accuracy, PPV and NPV of FNA-Tg were 95.7%, 95.5%, 95.6%, 97.8% and 91.3%, respectively. The sensitivity and accuracy of the combination of FNAC and FNA-Tg were significantly higher than that of FNAC alone (p<0.05). The diagnostic performance of FNA-Tg was not significantly different between cases with or without RAI ablation, and the serum TgAb levels did not interfere with FNA-Tg measurements. Conclusions: Measurement of FNA-Tg is useful. The combination of FNAC and FNA-Tg is more sensitive and accurate for detecting lymph node metastases in patients with a history of DTC than FNAC alone. Serum TgAbs appear to be irrelevant for measurement of FNA-Tg.

Exploration of Foreign Curriculums for the Improvement of the Korean Middle School Statistical Curriculum: Focusing on learning elements in Korea, the United States, Singapore, and Japan (중학교 통계영역의 교육과정 개선을 위한 외국 교육과정의 탐색: 한국, 미국, 싱가포르, 일본의 학습 요소 중심으로)

  • Kim, Somin
    • Journal of the Korean School Mathematics Society
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    • v.22 no.4
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    • pp.501-520
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    • 2019
  • This study compared and analyzed Korean, American, Singaporean, and Japanese middle school mathematics curriculum standards and the learning contents in statistics. Through a comparative analysis of the curriculums of these four countries, I found several overall features and differences between the curriculums. First, all four countries emphasized statistical education in a real-life context. Second, all four countries emphasized the use of technological tools. Third, there is a middle school grade in which only Korea does not deal with statistical domains. Fourth, the statistical areas of the United States, Singapore, and Japan focused on identifying trends or variability in data distribution. Fifth, I have found some contents that only Korea does not deal with. Based on this, the following recommendations were developed for the development of the next curriculum and new textbooks in Korea. First, the statistics curriculum should be changed from one that focuses on understanding statistical concepts to one that focuses on statistical activity that utilizes these concepts. Second, in terms of middle school statistical curriculum contents, the addition of interquartile range (IQR) and box plots as learning contents should be considered. IQR and box plots are simple and practical techniques for the comparison of multiple sets of data that can be easily learned and drawn by middle school level students and applied to real-life-related statistical data to expand statistical literacy. Through this study, it is suggested that IQR and box plots need to be included in the statistical curriculum of middle schools in Korea.

Performance Analysis of Simultaneous Liftable 3D Concrete Printing Based on Statistical Analysis Algorithm (통계분석 알고리즘 프로그램을 활용한 동시 인상 3D 콘크리트 프린팅의 성능 분석)

  • Yoon-Chul Kim;Sung-Jo Kim;Bongsik Kim;Yongsoo Ji;Tong-Seok Han
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.36 no.6
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    • pp.407-414
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    • 2023
  • In this study, an automated jack-up system, applicable to various fields, was employed for 3D concrete printing and developed as a simultaneous liftable 3D concrete printing system. This developed printing system enables safe and precise jack-up by monitoring the measured jack-up distance using Pearson correlation coefficient analysis and a hydraulic system with interquartile range analysis in real-time during 3D concrete printing operations. It is possible to secure the quality of 3D concrete printing structures, which is essential for expanding the application of 3D concrete printing to construct larger structures. Specimens were printed using both conventional 3D concrete printing and simultaneous liftable 3D concrete printing to evaluate the system performance. The printed specimens were investigated using a 3D scanner. The layer-wise diameter and angle of intersection of the scanned specimens were measured, and an analysis was performed to verify the advantages of the simultaneous liftable 3D concrete printing.

Effect of Stent Placement on Survival in Patients with Malignant Portal Vein Stenosis: A Propensity Score-Matched Study

  • Dong Jae Shim;Jong Woo Kim;Doyoung Kim;Gi-Young Ko;Dong Il Gwon;Ji Hoon Shin;Yun-Jung Yang
    • Korean Journal of Radiology
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    • v.23 no.1
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    • pp.68-76
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    • 2022
  • Objective: Percutaneous portal vein (PV) stent placement can be an effective treatment for symptoms associated with portal hypertension. This study aimed to evaluate the effect of PV stenting on the overall survival (OS) in patients with malignant PV stenosis. Materials and Methods: Two groups of patients with malignant PV stenosis were compared in this retrospective study involving two institutions. A total of 197 patients who underwent PV stenting between November 2016 and August 2019 were established as the stent group, whereas 29 patients with PV stenosis who were treated conservatively between July 2013 and October 2016 constituted the no-stent group. OS was compared between the two groups before and after propensity score matching (PSM). Risk factors associated with OS were evaluated using the Cox proportional hazards model. Procedure-associated adverse events were also evaluated. Results: The stent group finally included 100 patients (median age, 65 [interquartile range, 58-71] years; 64 male). The no-stent group included 22 patients (69 [61-75] years, 13 male). Stent placement was successful in 95% of attempted cases, and the 1- and 2-year stent occlusion-free survival rate was 56% (95% confidence interval, 45%-69%) and 44% (32%-60%), respectively. The median stent occlusion-free survival time was 176 (interquartile range, 70-440) days. OS was significantly longer in the stent group than in the no-stent group (median 294 vs. 87 days, p < 0.001 before PSM, p = 0.011 after PSM). The 1- and 3-year OS rates before PSM were 40% and 11%, respectively, in the stent group. The 1-year OS rate after PSM was 32% and 5% in the stent and no-stent groups, respectively. Anemia requiring transfusion (n = 2) and acute thrombosis necessitating re-stenting (n = 1) occurred in three patients in the stent group within 1 week. Conclusion: Percutaneous placement of a PV stent may be effective in improving OS in patients with malignant PV stenosis.

Prognostic Implication of Right Ventricle Parameters Measured on Preoperative Cardiac MRI in Patients with Functional Tricuspid Regurgitation

  • Yura Ahn;Hyun Jung Koo;Joon-Won Kang;Won Jin Choi;Dae-Hee Kim;Jong-Min Song;Duk-Hyun Kang;Jae-Kwan Song;Joon Bum Kim;Sung-Ho Jung;Suk Jung Choo;Cheol Hyun Chung;Jae Won Lee;Dong Hyun Yang
    • Korean Journal of Radiology
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    • v.22 no.8
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    • pp.1253-1265
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    • 2021
  • Objective: To investigate the prognostic value of preoperative cardiac magnetic resonance imaging (MRI) for long-term major adverse cardiac and cerebrovascular events (MACCEs) in patients undergoing tricuspid valve (TV) surgery for functional tricuspid regurgitation (TR). Materials and Methods: The preoperative cardiac MR images, New York Heart Association functional class, comorbidities, and clinical events of 78 patients (median [interquartile range], 59 [51-66.3] years, 28.2% male) who underwent TV surgery for functional TR were comprehensively reviewed. Cox proportional hazards analyses were performed to assess the associations of clinical and imaging parameters with MACCEs and all-cause mortality. Results: For the median follow-up duration of 5.4 years (interquartile range, 1.2-6.6), MACCEs and all-cause mortality were 51.3% and 23.1%, respectively. The right ventricular (RV) end-systolic volume index (ESVI) and the systolic RV mass index (RVMI) were higher in patients with MACCEs than those without them (77 vs. 68 mL/m2, p = 0.048; 23.5 vs. 18.0%, p = 0.011, respectively). A high RV ESVI was associated with all-cause mortality (hazard ratio [HR] per value of 10 higher ESVI = 1.10, p = 0.03). A high RVMI was also associated with all-cause mortality (HR per increase of 5 mL/m2 RVMI = 1.75, p < 0.001). After adjusting for age and sex, only RVMI remained a significant predictor of MACCEs and all-cause mortality (p < 0.05 for both). After adjusting for multiple clinical variables, RVMI remained significantly associated with all-cause mortality (p = 0.005). Conclusion: RVMI measured on preoperative cardiac MRI was an independent predictor of long-term outcomes in patients who underwent TV surgery for functional TR.

Short-term comparative outcomes between reverse shoulder arthroplasty for shoulder trauma and shoulder arthritis: a Southeast Asian experience

  • Ng, Julia Poh Hwee;Tham, Sherlyn Yen Yu;Kolla, Saketh;Kwan, Yiu Hin;Tan, James Chung Hui;Teo, Timothy Wei Wen;Wee, Andy Teck Huat;Toon, Dong Hao
    • Clinics in Shoulder and Elbow
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    • v.25 no.3
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    • pp.210-216
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    • 2022
  • Background: Reverse shoulder arthroplasty (RSA), first introduced as a management option for cuff tear arthropathy, is now an accepted treatment for complex proximal humeral fractures. Few studies have identified whether the outcomes of RSA for shoulder trauma are comparable to those of RSA for shoulder arthritis. Methods: This is a retrospective, single-institution cohort study of all patients who underwent RSA at our institution between January 2013 and December 2019. In total, 49 patients met the inclusion criteria. As outcomes, we evaluated the 1-year American Shoulder and Elbow Surgeons (ASES) and Constant shoulder scores, postoperative shoulder range of motion, intra- and postoperative complications, and cumulative revision rate. The patients were grouped based on preoperative diagnosis to compare postoperative outcomes across two broad groups. Results: The median follow-up period was 32.8 months (interquartile range, 12.6-66.6 months). The 1-year visual analog scale, range of motion, and Constant and ASES functional scores were comparable between RSAs performed to treat shoulder trauma and that performed for arthritis. The overall complication rate was 20.4%, with patients with a preoperative diagnosis of arthritis having significantly more complications than those with a preoperative diagnosis of trauma (34.8% vs. 7.7%). Conclusions: Patients who underwent RSA due to a proximal humeral fracture or dislocation did not fare worse than those who underwent RSA for arthritis at 1 year, in terms of both functional and radiological outcomes.

Short-term Associations of Air Pollution with Postneonatal Infant Death in Seoul, Korea, 1999-2003

  • Lee, Jong-Tae;Cho, Yong-Sung;Son, Ji-Young
    • Journal of Environmental Health Sciences
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    • v.34 no.5
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    • pp.361-368
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    • 2008
  • Objective to assess whether exposure to air pollutants is associated with postneonatal infant death, using a timeseries methodology, between 1999 and 2003 in Seoul, Korea.. Methods We investigated the short-term effects of air pollution for 548,725 live births during the study period. The daily count of postneonatal infant deaths from all causes and from SIDS (sudden infant death syndrome) by birth order was analyzed by a Generalized Additive Poisson model, with controlling for the effects of seasonal trends, air temperature, relative humidity, barometric pressure, and day of the week as covariates. Results During the study period, we observed 699 deaths from all causes and 47 deaths from SIDS. We did not find any significant associations between daily mortality and ambient levels of air pollutants except for CO and $NO_2$. The estimated relative risk of postneonatal infant death from all causes was 1.17 (95% CI=1.04-1.32) and 1.16 (95% CI=1.03-1.29) by IQR (interquartile range) for CO and $NO_2$ respectively. Also, we observed no clear trend of the mortality effects of air pollution by birth orders. Conclusion In conclusion, our findings suggest that air pollution, in general, influenced adversely postneonatal infant death from all-cause and SIDS although it was not statistically significant. This study may support that the rationale.

Standardized Body Type and the Suitability of Figures for the Twenties Women (20대 여성의 표준체형과 인대 적합성에 관한 연구)

  • Koo, Mi-Ji;Lee, Jeong-Im
    • Fashion & Textile Research Journal
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    • v.7 no.6
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    • pp.601-608
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    • 2005
  • This research investigated the present state of the dress forms used by clothing manufacturers and proposed procedure to bring out the standardized body type and figure for women in twenties. The result of questionnaire showed chief pattern maker's thoughts that dress form should be differently made for each age group and should be more reflected the standard body than the idea body. The standardized body type was made from the standardized posture and size which were analyzed from the interquartile range(IQR) of 314 subjects. The standardized size could be verified as for the balanced body shape of twenties through making the standard dress form. The standardized form(S form) was compared with three kinds of forms(A, K and P) for investigating the suitability of forms. K form was very similar to S form, Educational P form and manufacturer's A form had quite big differences from S form at the important areas for making clothing. The side shapes of A, K and P forms showed differences at back bending, neck angle and hip shape from S form. A form was comparatively smooth and flat. This results could be used as the practical standard to improve the suitability of size and shape in the dress forms of manufacturers and educators.

A study on the styloid process in panoramic radiographs (파노라마방사선사진을 이용한 경상돌기에 관한 연구)

  • Hwang Ji-Young;Hwang Eui-Hwan;Lee Sang-Rae
    • Imaging Science in Dentistry
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    • v.35 no.2
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    • pp.105-110
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    • 2005
  • Purpose : To find statistically based information about the natural variation in the length of the styloid process and to show the influence of the gender and age on the length of the styloid process. Materials and Methods : 1,300 panoramic radiographs were retrieved from inactive files at the Dental Hospital of Kyung Hee University. Measurements of the length of the styloid process were made directly on the radiographs from the inferior margin of the tympanic plate to the tip of the styloid process. Results The mean length of 948 styloid processes was $25.2mm{\pm}6.6$. The median was 24.5 mm, and the interquartile range was 7 mm. The mean length was 25.7 mm for male and 24.6 mm for female. All percentile was greater for male than for female. The median is 25 mm for male and 24 mm for female. Conclusion : This study suggests that the difference of the styloid process length between genders was statistically significant and the length of styloid process was significant increased with age until 30 years.

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Development of data processing component module for the flood management in an agricultural watershed (농촌유역 홍수관리를 위한 자료처리 요소모듈 개발)

  • Lee, Do Gil;Kang, Moon Seong;Park, Jihoon;Ryu, Jeong Hoon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.289-289
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    • 2016
  • 신뢰성 높은 홍수관리는 경향성 분석, 이상치 판정 등의 전처리를 수행한 입력 자료를 구축하는 것을 필요로 한다. 경향성 분석은 방법에 따라 경향성의 유무가 다르게 나타나기 때문에 하나의 방법으로만 판단하기 어려우며, 이상치 분석은 지역 특성에 따라 기준이 변동하므로 일정한 기준을 적용하기가 어려워 주로 수동으로 이루어지며 이 작업을 완료하는 데에는 많은 시간이 소요된다. 입력 자료 전처리에 수반되는 비용과 시간을 절감하기 위해 이러한 문제점의 개선이 필요한 실정이다. 따라서 본 연구의 목적은 농촌유역 홍수관리를 위한 자료처리 요소 모듈을 개발하는 데 있다. 홍수관리를 위한 자료처리 요소 모듈은 크게 기상자료의 경향성을 분석하는 모듈과 수위자료의 이상치를 탐지하고 판정하는 모듈로 구성하였다. 경향성 분석 모듈은 모수적 방법인 t-test와 비모수적 방법인 Hotelling-Pabst test 및 Mann-Kendall test를 분석 방법으로 제공하여 하나의 입력 자료로 세 가지 방법으로 분석한 결과를 비교할 수 있도록 개발하였다. 이상치 탐지 모듈은 IQR (interquartile range) 규칙과 규칙기반의 방법을 이용한 이상치 탐지를 제공할 수 있도록 개발하였다. 개발된 모듈은 한강 유역의 용당저수지에 적용하여 검정을 실시하였다. 본 연구에서 개발된 농촌유역 홍수관리를 위한 자료처리 요소 모듈은 추후 홍수관리 및 그에 관한 연구를 하는데 있어 활용될 수 있을 것으로 기대된다.

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