• Journal of Trauma and Injury
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• v.28 no.3
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• pp.134-143
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• 2015

Purpose: Many patients are injured by trauma. And some of them expire due to severity of trauma. Various scoring systems have been introduced in grading severity and predicting mortality of trauma patients. This study is to evaluation the usefulness of factors for determining the severity and predicting the prognosis of the trauma victims. Methods: Data on the patients who visited our Emergency departments from January 2010 to December 2011 were retrospectively reviewed using electronic medical records. The patients were activated severe trauma team calling system. The patients were categorized as survivors and non-survivors. Univariated associations were calculated, and a multiple logistic regression analysis was used to determine variables associated with hospital mortality. Results: Two hundred sixty two(262) patients were enrolled, and the mortality rate was 25.6%. By multivariate analysis, lower respiration rate, lower Glasgow Coma Score, higher International Normalized Ratio and emergency transfusion within 6 hours were expected as severity and prognosis predict factors (each of odds ratio were 24.907, 14.282, 2.667 and 16.144). Conclusion: As predict factors, respiration rate, Glasgow Coma Score, International Normalized Ratio and emergency transfusion, are useful determining the severity and predicting prognosis of trauma victims.

• Korean Journal of Clinical Pharmacy
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• v.23 no.3
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• pp.232-238
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• 2013

Background: Although thromboembolism is common and one of the major causes of mortality in cancer patients, maintaining therapeutic anticoagulation effect with warfarin is challenging. This study aimed to determine the prevalence and the causes of non-therapeutic INR (International Normalized Ratio) in cancer patients. Methods: Medical and pharmacy records for cancer patients managed by the pharmacist-run anticoagulation service (ACS) between May, 2010 and April, 2011 at Seoul National University Hospital were retrospectively reviewed. The causes of non-therapeutic INR were identified and compared with the results from a former study with mechanical heart valve patients. Results: A total of 335 cancer patients and 6,737 patient-visits were analyzed producing 68% (n=4,590) of non-therapeutic INR readings. Eighty-five percent of the non-therapeutic INR readings were categorized as sub-therapeutic. Frequent causes linked to non-therapeutic INR included inadequate dosage adjustment (21.8%), changes in health status (11.8%), dietary changes (8.1%), and drug interactions (4.2%). More than half of the non-therapeutic INR values had no known etiology. As causes for non-therapeutic INR, changes in health status (p<0.0001), adverse reactions (p<0.0001), and dietary changes (p=0.017) were statistically more frequent in cancer patients than in patients with mechanical heart valves. Furthermore, exposure to sub-therapeutic INR were more prevalent in cancer patients than in patients with mechanical heart valve (p<0.0001). Conclusions: This study shows that there is a tendency to keep the level of INR low and that health status change, dietary change, and drug interactions are found to be frequent causes for non-therapeutic INR in cancer patients.

• International Journal of Fluid Machinery and Systems
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• v.9 no.4
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• pp.338-353
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• 2016

Information on the surge behaviors and stall stagnation boundaries for a nine-stage axial flow compressor are summarized on the basis of analytical data in comparison with those for a single-stage one, with attention to the pressure ratio effect. The general trends of the surge loop behaviors of the pressure-mass flow are similar for both compressors including the fact that the subharmonic surges tend to appear very near the stall stagnation boundaries. With respect to the nine-stage compressor, however, the mild loops in the subharmonic surges tend to be very small in size relative to the deep loops, and at the same time, insufficient surge recovery phenomenon, which is a kind of subharmonic surge, appears also far from the stagnation boundary for relatively short delivery flow-paths. The latter is found to be a rear-stage surge caused by unstalling and re-stalling of the rear stages with the front-stages kept in stall in the stalled condition of the whole compressor, which situation is caused by stage-wise mismatching in the bottom pressure levels of the in-stall multi-stage compressor. The fundamental information on the stall stagnation boundaries is given by a group of normalized geometrical parameters including relative delivery flow-path length, relative suction flow-path length, and sectional area-pressure ratio, and by another group of normalized frequency parameters including relative surge frequencies, modified reduced resonance frequencies, and modified reduced surge frequencies. Respective groups of the normalized parameters show very similar tendency of behaviors for the nine-stage compressor and the single-stage compressor. The modified reduced resonance frequency could be the more reasonable parameter suggesting the flow-induced oscillation nature of the surge phenomena. It could give the stall stagnation boundary in a more unified manner than the Greitzer's B parameter.

• International Journal of Control, Automation, and Systems
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• v.6 no.6
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• pp.818-827
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• 2008

In this paper, we propose a new noise estimation and reduction algorithm for stationary and nonstationary noisy environments. This approach uses an algorithm that classifies the speech and noise signal contributions in time-frequency bins. It relies on the ratio of the normalized standard deviation of the noisy power spectrum in time-frequency bins to its average. If the ratio is greater than an adaptive estimator, speech is considered to be present. The propose method uses an auto control parameter for an adaptive estimator to work well in highly nonstationary noisy environments. The auto control parameter is controlled by a linear function using a posteriori signal to noise ratio(SNR) according to the increase or the decrease of the noise level. The estimated clean speech power spectrum is obtained by a modified gain function and the updated noisy power spectrum of the time-frequency bin. This new algorithm has the advantages of much more simplicity and light computational load for estimating the stationary and nonstationary noise environments. The proposed algorithm is superior to conventional methods. To evaluate the algorithm's performance, we test it using the NOIZEUS database, and use the segment signal-to-noise ratio(SNR) and ITU-T P.835 as evaluation criteria.

• Korean Journal of Applied Biomechanics
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• v.16 no.2
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• pp.1-8
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• 2006

The purpose of this study was to evaluate normalized jerk according to shoes, slope, and velocity during walking. Eleven different test subjects used three different types of shoes (running shoes, mountain climbing boots, and elevated forefoot walking shoes) at various walking speeds(1.19, 1.25, 1.33, 1.56, 1.78, 1.9, 2, 2.11, 2.33m/sec) and gradients(0, 3, 6, 10 degrees) on a treadmill. Since there were concerns about using the elevated forefoot shoes on an incline, these shoes were not used on a gradient. Motion Analysis (Motion Analysis Corp. Santa Rosa, CA USA) was conducted with four Falcon high speed digital motion capture cameras. Utilizing the maximum smoothness theory, it was hypothesized that there would be differences in jerk according to shoe type, velocity, and slope. Furthermore, it was assumed that running shoes would have the lowest values for normalized jerk because subjects were most accustomed to wearing these shoes. The results demonstrated that elevated forefoot walking shoes had lowest value for normalized jerk at heel. In contrast, elevated forefoot walking shoes had greater normalized jerk at the center of mass at most walking speeds. For most gradients and walking speeds, hiking boots had smaller medio-lateral directional normalized jerk at ankle than running shoes. These results alluded to an inverse ratio for jerk at the heel and at the COM for all types of shoes. Furthermore, as velocity increased, medio-lateral jerk was reduced for all gradients in both hiking boots and running shoes. Due to the fragility of the ankle joint, elevated forefoot walking shoes could be recommended for walking on flat surfaces because they minimize instability at the heel. Although the elevated forefoot walking shoes have the highest levels of jerk at the COM, the structure of the pelvis and spine allows for greater compensatory movement than the ankle. This movement at the COM might even have a beneficial effect of activating the muscles in the back and abdomen more than other shoes. On inclines hiking boots would be recommended over running shoes because hiking boots demonstrated more medio-lateral stability on a gradient than running shoes. These results also demonstrate the usefulness of normalized jerk theory in analyzing the relationship between the body and shoes, walking velocity, and movement up a slope.

• Structural Engineering and Mechanics
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• v.57 no.1
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• pp.179-200
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• 2016

In this paper the differential transformation method (DTM) is utilized for vibration and buckling analysis of nanotubes in thermal environment while considering the coupled surface and nonlocal effects. The Eringen's nonlocal elasticity theory takes into account the effect of small size while the Gurtin-Murdoch model is used to incorporate the surface effects (SE). The derived governing differential equations are solved by DTM which demonstrated to have high precision and computational efficiency in the vibration analysis of nanobeams. The detailed mathematical derivations are presented and numerical investigations are performed while the emphasis is placed on investigating the effect of thermal loading, small scale and surface effects, mode number, thickness ratio and boundary conditions on the normalized natural frequencies and critical buckling loads of the nanobeams in detail. The results show that the surface effects lead to an increase in natural frequency and critical buckling load of nanotubes. It is explicitly shown that the vibration and buckling of a nanotube is significantly influenced by these effects and the influence of thermal loadings and nonlocal effects are minimal.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.316-321
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• 2022

Since 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly, infecting millions of people worldwide. On March 11, 2020, the World Health Organization declared coronavirus disease (COVID-19) a pandemic owing to the worldwide spread of SARS-CoV-2, which created an unprecedented burden on the global healthcare system. In this context, there are increasing concerns regarding co-infections with other respiratory viruses, such as the influenza virus. In this study, clinical data of patients infected with SARS-CoV-2 and other respiratory viruses were compared with patients infected with SARS-CoV-2 alone. The hematology and blood biochemistry results of 178 patients infected with SARS-CoV-2 , who were tested on admission, were retrospectively reviewed. In patients with SARS-CoV-2 and adenovirus co-infection, C-reactive protein levels were elevated on admission, whereas lactate dehydrogenase (LDH), prothrombin time, international normalized ratio, activated partial thromboplastin clotting time, and bilirubin values were all within the normal range. Moreover, patients with SARS-CoV-2 and human bocavirus co-infection had low LDH and high bilirubin levels on admission. These findings reveal the clinical features of respiratory virus and SARS-CoV-2 co-infections and support the development of appropriate approaches for treating patients with SARS-CoV-2 and other respiratory virus co-infections.

• Clinical and Experimental Pediatrics
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• v.64 no.1
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• pp.31-36
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• 2021

Background: The diagnosis of esophageal varices (EV) is based on the findings of esophagogastroduodenoscopy (EGD), biopsy, and serum markers. Thus, noninvasive cost-effective tests through which high-risk EV children can be diagnosed are needed. Purpose: This cross-sectional study aimed to identify the noninvasive markers for EV in children with liver cirrhosis. Methods: A total of 98 children with liver cirrhosis were evaluated in this study. The spleen size, platelet count, serum albumin, liver function test results, and risk scores were evaluated prior to endoscopy. The endoscopic investigations aimed to identify the presence of EV and red signs, and determine varices sizes. Results: Endoscopy revealed varices in 43 subjects (43.9%). The spleen size, platelet count, international normalized ratio, aspartate aminotransferase to platelet ratio index (APRI), platelet count to spleen size ratio, and risk score differed significantly between patients with and without EV on univariate analysis; however, the logistic regression analysis showed no differences, indicating that none of these parameters were independently associated with the presence of EV. Conclusion: Platelet count, risk score, platelet count to spleen size, and APRI can be useful tools for the identification of high-risk patients with EV and might reduce the need for invasive methods like EGD.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.31 no.6_2
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• pp.521-527
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• 2013

Rule set is an important step which impacts significantly on accuracy of object-oriented classification result. Therefore, this paper proposes a rule set to extract land cover from Landsat Thematic Mapper (TM) imagery acquired in Donganh, Hanoi, Vietnam. The rules were generated to distinguish five classes, namely river, pond, residential areas, vegetation and paddy. These classes were classified not only based on spectral characteristics of features, but also indices of water, soil, vegetation, and urban. The study selected five indices, including largest difference index max.diff; length/width; hue, saturation and intensity (HSI); normalized difference vegetation index (NDVI) and ratio vegetation index (RVI) based on membership functions of objects. Overall accuracy of classification result is 0.84% as the rule set is used in classification process.

• The Journal of the Korean dental association
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• v.57 no.10
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• pp.623-628
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• 2019

Warfarin is an anticoagulant involved in the production of vitamin K dependent blood clotting factors. Dentists should be familiar with the appropriate assessment methods and considerations for the treatment of patients taking warfarin. Dental surgery with the moderate risk of bleeding can be performed without stopping the drug through preoperative examination of the INR(international normalized ratio) value and evaluation. When performing a surgery with a high risk of bleeding, it is necessary to evaluate whether the drug can be discontinued, what the duration is, and the risk of discontinuation. Hemostasis can be obtained by local methods in most cases of postoperative bleeding in patients taking appropriately adjusted doses of warfarin.