• 제목/요약/키워드: International Joint Research

검색결과 421건 처리시간 0.023초

급성관상동맥 증후군 치료를 위한 국내·외 항혈소판제 약물요법 가이드라인 비교 연구 (A Comparative Study the USA, Europe and Korea Guidelines of Antiplatelet Therapy for Patients with Acute Coronary Syndrome)

  • 정은주;이채원;백인환
    • 한국임상약학회지
    • /
    • 제25권3호
    • /
    • pp.200-208
    • /
    • 2015
  • Objective: Patients with acute coronary syndrome (ACS) are typically managed with dual antiplatelet therapy of acetylsalicylic acid (aspirin) and $P2Y_{12}$ receptor inhibitor. In this study, we discussed current and previous antiplatelet therapy guidelines and compared with guidelines of the USA (ACC/AHA), Europe (ESC) and Korea (KSC). Method: This study investigated from ACC/AHA Joint Guidelines (the USA), ESC Clinical Practice Guidelines (Europe) and Korea Society of Interventional Cardiology (Korea) web site, respectively. Results: It is significant that difference between the current and the previous guidelines was integration of terminology from clopidogrel to $P2Y_{12}$ receptor inhibitors since prasugrel and ticagrelor, new antiplatelet drugs, has been added. The other difference was all three guidelines has differences in dose of aspirin. The most notable difference was class of recommendation(COR) in $P2Y_{12}$ receptor inhibitors. ACC/AHA and Korean guidelines recommend clopidogrel, prasugrel, and ticagrelor with COR IB; whereas, ESC recommend prasugrel and ticagrelor with IB which is higher than clopidogrel with IC. Conclusion: This research addresses important movement to revise the Korean existing guideline recommendations. New Korean antiplatelet therapy guideline should be avoiding obvious differences in ACC/AHA and ESC guidelines and harmonizing international guidelines.

Debt Finance among Vietnamese Enterprises: The Influence of Managers' Gender

  • HO, Hoang Lan;DAO, Minh Hoa;PHAN, The Cong
    • The Journal of Asian Finance, Economics and Business
    • /
    • 제7권9호
    • /
    • pp.229-239
    • /
    • 2020
  • This paper examines the impact of gender on access to debt finance among Vietnamese enterprises. The paper investigates data and variables retrieved from the World Bank Enterprise Survey dataset using five Probit models. The regression results suggest that there exist more unfavourable debt financing conditions for women-led firms (WLF), measured as a lower probability of having loan applications fully approved. Firm's age, working sector, and perception of access to finance as a difficulty are found to have explanatory power on the discrimination. More importantly, the perception of debt finance as a difficulty or firms' level of confidence significantly explains the variance of the dependent variable of probability of loan approval, or gender effect would be more pronounced if the firm already has a low level of confidence. The paper also contributes in testing for the gender effect on Vietnamese enterprises from different sectors and scale, unlike other prior research papers focusing on specific sectors and/or small and medium enterprises only. The findings are highly useful for Vietnamese credit institutions to set out a specific business policy to attract more WLFs and help promoting gender equality in the working environment, especially in debt financing, which is often neglected in existing regulation and policy frameworks.

$\ll$황제내경(黄帝内经)$\gg$ "진액(津液)" 개념고변(概念考辨) (Analysis of the concept of body fluid in "Hwangjenaegyeong(黃帝內經)")

  • 곡봉;김효철
    • 대한한의학원전학회지
    • /
    • 제23권1호
    • /
    • pp.11-13
    • /
    • 2010
  • In this article, the concept of body fluid is explained in three aspects: the word meaning of body fluid, the origins of the definitions of the body fluid concept and the connotation and extension of body fluid. Investigating data about the time Hwangjenaegyeong(黃帝內經) was written, the author discovers that the meaning of "Aek(液)" is clear, but there are still questions about the meaning of "Jin(津)". The concept of body fluid derived from observation of life phenomenon and ancient philosophy on the "water". The concept of body fluid should be expressed as that body fluid is a general term for all normal liquids in the body. Within the meridians, as the composition of blood components; outside the meridians, constituting the intrinsic body fluids of various organs and tissues. This is the main part of body fluid, coming from diet, constituting the human body and maintaining human life activities, playing the roles of moistening and nourishing various of organs and tissues of the body. In addition, Interstitial fluid, all kinds of normal liquid secretion and metabolic products, such as sweat, tears, nasal discharge, saliva, slobber, gastric juice, intestinal fluid, urine, joint fluid, latex and so on, both belong to body fluid.

EMG Activities of Vastus Muscles are Related to the Shoe-heel Heights in Female Patients with Patellofemoral Pain

  • Chon, Seung-Chul;Lee, Byung-Ki;Yoon, Tae-Hyung
    • International Journal of Contents
    • /
    • 제6권1호
    • /
    • pp.41-46
    • /
    • 2010
  • The aim of this study was to investigate the effect of different shoe-heel heights on the surface electromyographic (EMG) activity of vastus medialis (VM) and vastus lateralis (VL) during treadmill walking in female patients with patellofemoral pain (PFP). Nineteen women with PFP participated in this research. EMG signals were recorded from the VM and VL of both sides and were compared during the treadmill walking. The subjects walked on a treadmill wearing shoes of three different heel heights: 1 cm, 3 cm and 7 cm. Each subject walked on a treadmill for five minutes at a speed of 2 km/hour with three minutes resting intervals between consecutive trials. The data were analyzed by one-way repeated-measures analysis of variance. The results of the present study indicate that EMG data of the VM and VL of female patients with PFP did improve with an increase in the height of the shoe heel, which were statistically significant. Additionally, the EMG activity of VM increased more dramatically than that of VL associated with the task of walking with high-heeled shoes on the treadmill. This study suggests that the type of high-heeled shoes is related to the VM and VL muscle activation patterns contributing to knee joint pathologies in female patients with PFP.

Effective Notch Stress Method for Fatigue Evaluation of Welded Joints in a Steel Bridge Deck

  • Sim, Hyoung-Bo
    • International Journal of Railway
    • /
    • 제5권2호
    • /
    • pp.89-92
    • /
    • 2012
  • Effective notch stress, as an approach to evaluate the local stress at a notch (weld toe or root), is defined as the total stress assuming linear-elastic material behavior. This method can be effectively used to evaluate the fatigue performance of welded joints. In this study, finite element analysis results using the effective notch stress method were correlated with fatigue test results of rib-to-deck welded joints in a steel orthotropic bridge deck. Effective notch stress approach provided a good correlation with the crack pattern observed in the full-scale fatigue test. A higher effective notch stress at the critical weld toe than at the weld root was consistent with the dominant crack pattern observed at the weld toe during testing. The effective notch stress at the toe on the deck plate was about 80% higher than that on the rib; no cracks at the weld toe on the rib in the testing were observed. Maximum effective notch stress at the weld root occurred on the upper side of the root notch, which indicates that cracks are more likely to propagate into the deck plate, not into the weld metal. This is also consistent with the observed crack pattern in which the crack from the root propagated upward into the deck plate. No such crack pattern, propagating into the weld metal, was observed in the testing.

Developments of Fire-Resistant Wooden Structural Components and Those Applications to Mid- to High-Rise Buildings in Japan

  • Hanai, Atsunari;Nakai, Masayoshi;Matsuzaki, Hiroyuki;Ohashi, Hirokazu
    • 국제초고층학회논문집
    • /
    • 제9권3호
    • /
    • pp.221-233
    • /
    • 2020
  • Based on past experiences of natural disasters and fires in Japan, it is stipulated by law that fire-resistant buildings larger than a certain size should be unique in the world. Recent interest in global environmental issues has led to the active introduction of wooden buildings also in Japan, and it is expected that wooden buildings will become larger and higher in size. This paper introduces the background of the development of fire-resistant laminated timber with a "Self-Charring-Stop layer", the contents of this development including other related developments, and the application of these technologies. In addition, towards the realization of much larger and higher buildings in the future, the current problems and issues to be solved are set and the necessity of the future technological development is described. Finally, a conceptual model of wooden high-rise building is proposed, which will be able to be constructed in 2025 by the further technological development.

벼멸구(Nilaparvata lugens)와 끝동매미충(Nephotettix virescens)에 대(對)한 유기인계(有機燐系).Carbamate계(系) 살충제(殺蟲劑) 혼합(混合)의 협력작용(協力作用) (Joint Toxic Action of Mixtures of Organophosphorus and Carbamate Insecticides to Nilaparvata lugens and Nephotettix virescens)

  • 정부근;지전작;최승윤
    • 한국응용곤충학회지
    • /
    • 제26권3호
    • /
    • pp.159-163
    • /
    • 1987
  • 4종류(種類)의 살충제(殺蟲劑)(monocrotophos, diazinon(유기인계(有機燐系)), carbofuran, BPMC(carbamates계(系)) 중 두 약제(藥劑)를 택하여 1대 1 비율로 섞은 6가지 혼합제(混合劑) 조합(組合)들에 대한 협력작용(協力作用)을 보이는 조합(組合)을 발견하기 위하여 벼멸구(Nilaparvata lugens)와 끝동매미충(Nephotettix virescens)을 공시하여 실험을 수행하였다. 1. 벼멸구에 대하여는 carbofuran과 diazinon 조합(組合) 및 BPMC와 carbofuran 조합(組合)이 협력작용계수(協力作用係數) 200정도로 효과적이었다. 2. 끝동매미충(N. virescens)에 대하여는 diazinon과 monocrotophos 조합(組合)이 협력작용(協力作用) 계수(係數) 234로 효과적이었다. 3. 여타의 조합(組合)들은 독립용작(獨立用作)내지 부가작용을 보였다.

  • PDF

Comparison of Totally Prefabricated Bridge Substructure Designed According to Korea Highway Bridge Design (KHBD) and AASHTO-LRFD

  • Kim, Tae-Hoon
    • International Journal of Concrete Structures and Materials
    • /
    • 제7권4호
    • /
    • pp.319-332
    • /
    • 2013
  • The purpose of this study was to investigate the design comparison of totally prefabricated bridge substructure system. Prefabricated bridge substructure systems are a relatively new and versatile alternative in substructure design that can offer numerous benefits. The system can reduce the work load at a construction site and can result in shorter construction periods. The prefabricated bridge substructures are designed by the methods of Korea Highway Bridge Code (KHBD) and load and resistance factor design (AASHTO-LRFD). For the design, the KHBD with DB-24 and DL-24 live loads is used. This study evaluates the design method of KHBD (2005) and AASHTO-LRFD (2007) for totally prefabricated bridge substructure systems. The computer program, reinforced concrete analysis in higher evaluation system technology was used for the analysis of reinforced concrete structures. A bonded tendon element is used based on the finite element method, and can represent the interaction between the tendon and concrete of a prestressed concrete member. A joint element is used in order to predict the inelastic behaviors of segmental joints. This study documents the design comparison of totally prefabricated bridge substructure and presents conclusions and design recommendations based on the analytical findings.

한일 어업질서의 이행 실태와 어업관계의 개선 과제 (A Study on the Transition Situation of Korean-Japan Fisheries Agreement and Improvement Issue of Bilateral Fisheries Relations)

  • 김대영
    • 수산경영론집
    • /
    • 제47권1호
    • /
    • pp.31-45
    • /
    • 2016
  • This study aims to evaluate the status of implementation of bilateral-fishery order since the Korea-Japan Fisheries Agreement came into effect in 1999 in order to improve fisheries relationships between two countries. The agreement regulates bilateral-fishery order by the principle of the EEZ regime and mutual benefits among countries. (e.g. the mutual agreed fishing in EEZ and cooperation for resource management). However, the Korea-Japan Fisheries Agreement has some limitations such as reducing quotas of the mutual agreed fishing in EEZ, strengthening Japanese fisheries regulation, insufficient cooperation for fisheries management and joint countermeasures. In order to improve fisheries relationships between the two countries, it is imperative to rebalance quotas for the mutual agreed fishing in EEZ, to establish effective resource management systems in the Intermediate zone, to invigorate fisheries cooperation in the private sector, and to introduce new management systems by species over the all waters around East Asia. To accomplish such measures, it is necessary for Korean and Japanese governments to improve fisheries relationships based on trust and cooperation, achieving a win-win situation. Additionally, it is required to incorporate fisheries management among Korea, China, and Japan.

Commercialization of Genetically Modified Ornamental Plants

  • Chandler Stephen F.
    • Journal of Plant Biotechnology
    • /
    • 제5권2호
    • /
    • pp.69-77
    • /
    • 2003
  • The ornamental industry encompasses cut flower, pot plant, turfgrass and nursery stock production and is an important part of the agricultural sector. As internationally traded commodities, cut flowers and plants are an integral part of the economy of a number of developing countries in South America, the Caribbean and Africa. Genetic modification (GM) is a tool with great potential to the ornamental horticulture industry. The rapid progress in our knowledge of plant molecular biology can accelerate the breeding ornamental plants using recombinant DNA technology techniques. Not only is there the possibility of creating new, novel products the driver of the industry but also the potential to develop varieties requiring less chemical and energy inputs. As an important non-food agricultural sector the use of genetically modified (GM) ornamental crops may also be ideal for the intensive farming necessary to generate pharmaceuticals and other useful products in GM plants. To date, there are only a few ornamental GM products in development and only one, a carnation genetically modified for flower colour, in the marketplace. International Flower Developments, a joint venture between Florigene Ltd. in Australia and Suntory Ltd. of Japan, developed the GM carnations. These flowers are currently on sale in USA, Japan and Australia. The research, development and commercialization of these products are summarized. The long term prospects for ornamental GM products, like food crops, will be determined by the regulatory environment, and the acceptance of GM products in the marketplace. These critical factors will be analysed in the context of the current legislative environment, and likely public and industry opinion towards ornamental genetically modified organisms (GMO's).