• Ocean and Polar Research
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• v.24 no.4
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• pp.483-490
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• 2002

Detailed investigations on both submarine and subaerial volcaniclastic deposits around Dokdo were carried out to identify geomorphologic characteristics, stratigraphy, and associated depositional processes of Dokdo caldera. Dokdo volcano has a gently sloping summit (about 11km in diameter) and relatively steep slope (basal diameter is about 20-25 km) rising above sea level at about 2,270m. We found ragged, elliptical-form of Dokdo caldera with a diameter of about 2km estimated by Chirp (3-11 kHz) sub-bottom profile data and side scan sonar data for the central summit area of Dokdo volcano. We interpreted that the volcaniclastic deposits of Dokdo unconformably consist of the Seodo (west islet) and the Dongdo(east islet) formations based on internal structure, constituent mineral composition, and bedding morphology. The Seodo Formation mainly consisted of massive or inversely graded trachytic breccias (Unit S-I), overlain by fine-grained tuff (Unit S-II), which is probably supplied by mass-wasting processes resulting from Dokdo caldera collapse. The Dongdo Formation consists of alternated units of stratified lapilli tuff and inversely graded basaltic breccia (Unit D-I, Unit D-III, and Unit D-V), and massive to undulatory-bedded basaltic tuff breccias (Unit D-II and Unit D-IV) formed by a repetitive pyroclastic surge and reworking processes. Although, two islets of Dokdo are geographically near each other, they have different formations reflecting their different depositional processes and eruptive stages.

• Proceedings of the KSRS Conference
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• v.1
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• pp.21-24
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• 2006

Processes controlling the interannual variation of mixed layer temperature (MLT) averaged over the NINO3 domain ($150-90^{\circ}W$, $5^{\circ}N-5^{\circ}S$) are studied using an ocean data assimilation product that covers the period of 1993 to 2003. Advective tendencies are estimated here as the temperature fluxes through the domain's boundaries, with the boundary temperature referenced to the domain-averaged temperature to remove the dependence on temperature scale. The overall balance is such that surface heat flux opposes the MLT change but horizontal advection and subsurface processes assist the change. The zonal advective tendency is caused primarily by large-scale advection of warm-pool water through the western boundary of the domain. The meridional advective tendency is contributed mostly by Ekman current advecting large-scale temperature anomalies though the southern boundary of the domain. Unlike many previous studies, we explicitly evaluate the subsurface processes that consist of vertical mixing and entrainment. In particular, a rigorous method to estimate entrainment allows an exact budget closure. The vertical mixing across the mixed layer (ML) base has a contribution in phase with the MLT change. The entrainment tendency due to temporal change in ML depth is negligible comparing to other subsurface processes. The entrainment tendency by vertical advection across the ML base is dominated by large-scale changes in wind-driven upwelling and temperature of upwelling water. Tropical instability waves (TIWs) result in smaller-scale vertical advection that warms the domain during La Ni? cooling events. When the advective tendencies are evaluated by spatially averaging the conventional local advective tendencies of temperature, the apparent effects of currents with spatial scales smaller than the domain (such as TIWs) become very important as they redistribute heat within the NINO3 domain. However, such internal redistribution of heat does not represent external processes that control the domain-averaged MLT.

• Journal of Yeungnam Medical Science
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• v.22 no.1
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• pp.113-118
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• 2005

Diverticulosis of the small intestine is a rare entity, compared with that of duodenum or colon, and is found in only 1% of autopsied patients. The main complications are diverticulitis with or without a perforation, obstruction and hemorrhage, which are associated with a high mortality. Intussusception is primarily a disease of childhood; with only 5 to 10% of cases occurring in adults. In contrast to childhood intussusception, 90% of adult intussusception cases are had an associated pathologic processes. An inflammatory fibroid polyp is an uncommonly localized non-neoplastic lesion of the gastrointestinal tract. It occurs most often in the stomach and secondly in the ileum. It rarely occurs in other organs such as the colon, jejunum, duodenum and esophagus. We report a case of jejunal diverticulitis with a perforation combined with intussusception caused by an inflammatory fibroid polyp. A 78-year-old female presented with abdominal pain, fever and chill. Contrast CT scan showed intussusception of the ileum. The patient was treated with a small bowel segmental resection. After surgery, the specimen showed jejunal diverticulitis with perforation.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.9-17
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• 2004

Objective : Mesangial cell proliferation and excessive accumulation of extracellular matrix (ECM) proteins is the common pathologic feature of glomerulosclerosis, and platelet-derived growth factor (PDGF) BB-chain, transforming growth factor betal $(TGF-{\beta}1)$, cyclin dependent kinases (CDK) and CDK inhibitors mediated in these pathophysiological processes. Bupleurum falcatum which is one of the most widely used components in traditional oriental medicines, has multiple pharmacological effects, such as antipyretic, analgesic, immune modulating, anti-inflammatory, anti-allergic, anti-thrombotic, anti-atherosclerotic, and antitussive effects. Methods : In this study, we evaluated the influence of Bupleurum falcatum on mesangial cell proliferation, DNA synthesis and expression of PDGF-BB chain, $TGF-{\beta}1$, CDKI, CDK2, CDK4, p21 and p27 in fetal bovine serum (FBS)-activated human mesangial cell. Results : Bupleurum falcatum reduced the mesangial cell proliferation and DNA synthesis more than control and captopril. And in the ELISA analysis of $TGF-{\beta}1$, and RT-PCR of PDGF-BB chain, CDK1, CDK2, CDK4, p21, and p27, Bupleurum falcatum inhibited the expression of $TGF-{\beta}1$ protein and PDGF-BB, CDK1, CDK2 gene and promoted that of p21 gene in a dose-dependent manner in comparing with control and captopril. Conclusions: These results suggest that Bupleurum falcatum may inhibit the mesangial cell proliferation and DNA synthesis by regulation of PDGF-BB and $TGF-{\beta}1$ expressions, and by modulation of CDK1, CDK2 and p21 expression.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1497-1502
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• 2009

The cerebellum processes input from other areas of the brain, spinal cord and sensory receptors to provide precise timing for coordinated, smooth movements of the skeletal muscular system. A stroke affecting the cerebellum may cause vertigo, nausea, balance and coordination problems. The papers on central vertigo caused by cerebellar infarction were reported by Kim, Ku, Ko, Choi, and Han. Their cases were classed as Heo hoon, Dam hoon, and Sangchopungyeul yeul dam, and they treated with Jaeumkunbi-tang, Taeksa-tang, Cheonghunwhadam-tang gami, Cheonginwhadam-tang, Hachulbosim-tang. In this paper, three patients who suffered from vertigo were diagnosed as cerebellar infarction. They felt too giddy to walk without any help. After Oriental medical treatment based on Dongeuibogam, their sequelae of cerebellar infarction - vertigo, nausea, ataxia - had improved dramatically. So we report these cases, and suggest Oriental medical treatment based on Dongeuibogam have effect on cerebellar infarction. But more clinical case reports should be further examined.

• Applied Microscopy
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• v.29 no.1
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• pp.75-81
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• 1999

Optimum conditions for making the Au and Al internal standards for TEM have been determined experimentally. The Au internal standard was produced by sputter coating at 9mA for 100 seconds in low vacuum $(\leq1\times10^{-3})$. The Al internal standard was produced by evaporation coating at 7kV for 10 minutes in high vacuum $(\leq1\times10^{-5})$. Measurements of the lattice parameters of andalusite and albite feldspars with this Au internal standard resulted in errors of (a) $ \leq1.2%$ in precion and $\leq0.3%$ in accuracy for andalusite: (b) $\leq0.5%$ in precision and $\leq1.1%$ in accuracy for albite feldspars. The most significant error occurred from the measuring processes of distances and angles of electron diffraction patterns. By employing systematic procedures of measurement with high precision devices, this lattice parameter determination method utilizing the internal standard should be a good alternative to the conventional powder XRD method or the sophisticated CBED method for special samples.

• Journal of Korea Technology Innovation Society
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• v.16 no.3
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• pp.809-838
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• 2013

Innovation is the development of new customers value through solutions that meet new needs, inarticulate needs, or old customer and market needs in value adding new ways. This is accomplished through more effective products, processes, services, technologies, or ideas that are readily available to markets, governments, and society. Innovation differs from invention in that innovation refers to the use of a better and, as a result, novel idea or method, whereas invention refers more directly to the creation of the idea or method itself. Therefore, the utilization of patents is the most important of the three aspects (creation, protection and utilization) in the patent system for getting to actual innovation. In order to increase the patent use, the rates of the applied patents to a real industrial process and the bargain and license of patent rights should be promoted. For promoting technological innovation substantially, there is necessary to escape from dichotomy of weakening or enhancing patent protection in the discussion on the changes of patent system for "Adequate patent guarantees". Furthermore, the legal and institutional improvements to enable the use of patent should be discussed together. Recently, open innovation is a new paradigm that assumes that firms can and should use external ideas as well as internal ideas, and internal and external paths to market, as the firms look to advance their technology" or "Innovating with partners by sharing risk and sharing reward." The boundaries between a firm and its environment have become more permeable; innovations can easily transfer inward and outward. The central idea behind open innovation is that in a world of widely distributed knowledge, companies cannot afford to rely entirely on their own research, but should instead buy or license processes or inventions (i.e. patents) from other companies. In addition, internal inventions not being used in a firm's business should be taken outside the company. In the era of open innovation, more flexible patent use strategy is essential. It is important that improvements for the legal system in order that patented technology can be applied for products and processes in a real industrial between outside and inside of the firms.

• 한국연소학회:학술대회논문집
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• 2003.05a
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• pp.215-222
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• 2003

Mild combustion or Flameless oxidation(FLOX) have been considered as one of the most prospective clean-combustion technologies to meet both the targets of high process efficiency and low pollutant emissions. A mild combustor with high air preheating and strong internal exhaust gas recirculation is characterized by relatively low flame temperature, low NOx emissions, no visible flame and no sound. In this study, the Steady Flamelet Approach has been applied to numerically analyze the combustion processes and NOx formation in the mild combustor. The detailed discussion has been made for the basic characteristics of mild combustor, numerical results and limitation of the present combustion modeling.

• Advances in Energy Research
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• v.2 no.2
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• pp.73-84
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• 2014

Fuel cells of proton exchange membrane type (PEMFC) working with hydrogen in the anode and ambient air in the cathode ('air breathing') have been prepared and characterized. The cells have been studied with variable thickness of the cathode catalyst layer ($L_{CL}$), maintaining constant the platinum and ionomer loads. Polarization curves and electrochemical active area measurements have been carried out. The polarization curves are analyzed in terms of a model for a flooded passive air breathing cathode. The analysis shows that $L_{CL}$ affects to electrochemical kinetics and mass transport processes inside the electrode, as reflected by two parameters of the polarization curves: the Tafel slope and the internal resistance. The observed decrease in Tafel slope with decreasing $L_{CL}$ shows improvements in the oxygen reduction kinetics which we attribute to changes in the catalyst layer structure. A decrease in the internal resistance with $L_{CL}$ is attributed to lower protonic resistance of thinner catalyst layers, although the observed decrease is lower than expected probably because the electronic conduction starts to be hindered by more hydrophilic character and thicker ionomer film.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.04a
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• pp.23-26
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• 2003

Solid-state extrusion technique was employed for the improvement of mechanical properties of polylactic acid (PLLA) widely used as biodegradable internal fixation devices currently. Cylindrical billets were machined out from the vacuum compression-molded PLLA to have various diameters, and solid-state extrusion of the billets was performed at various drawing rates and at the extrusion temperature of $130^{\circ}C$. Throughout the whole processes the decrease in molecular weight was significantly suppressed to be about $10\%$. Flexural modulus and strength of PLLA increased up to 8.3 GPa and 221 MPa, respectively. Studies on the orientation and crystallinity of extruded PLLA could reveal the effects of billet morphology, draw ratio, and drawing rate on the flexural strengths of PLLA.