• Nuclear Engineering and Technology
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• v.47 no.3
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• pp.260-266
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• 2015

Twenty sodium-cooled fast reactors (SFRs) have provided valuable experience in design, licensing, and operation. This paper summarizes the important safety criteria and safety guidelines of intermediate sodium systems, steam generators, decay heat removal systems and associated construction materials and in-service inspection. The safety criteria and guidelines provide a sufficient framework for design and licensing, in particular by new entrants in SFRs.

• Journal of computational fluids engineering
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• v.21 no.1
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• pp.19-29
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• 2016

A Prototype Gen-IV Sodium-cooled Fast Reactor which is one of the $4^{th}$ generation nuclear reactors is in development by Korea Atomic Energy Research Institute. The reactor is composed of four main fluid systems which are categorized by its functions, i.e., Primary Heat Transport System, Intermediate Heat Transport System, Decay Heat Removal System and Sodium-Water Reaction Pressure Relief System. The coolant of the reactor is liquid sodium and sodium-to-sodium heat exchangers are installed at the interfaces between two fluid systems, Intermediate Heat Exchangers between the Primary Heat Transport System and the Intermediate Heat Transport System and Decay Heat Exchangers between the Primary Heat Transport System and the Decay Heat Removal System. For the design and performance analysis of the Intermediate Heat Exchanger and the Decay Heat Exchanger, a computer code was written during previous step of research. In this work, the computer code named "SHXSA" has been validated preliminarily by computational fluid dynamics simulations.

• Nuclear Engineering and Technology
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• v.41 no.10
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• pp.1323-1332
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• 2009

The IHX (Intermediate Heat eXchanger) for a pool-type SFR (Sodium-cooled Fast Reactor) system transfers heat from the primary high temperature sodium to the intermediate cold temperature sodium. The upper structure of the IHX is a coaxial structure designed to form a flow path for both the secondary high temperature and low temperature sodium. The coaxial structure of the IHX consists of a central downcomer and riser for the incoming and outgoing intermediate sodium, respectively. The IHX of a pool-type SFR is supported at the upper surface of the reactor head with an IHX support structure that connects the IHX riser cylinder to the reactor head. The reactor head is generally maintained at the low temperature regime, but the riser cylinder is exposed in the elevated temperature region. The resultant complicated temperature distribution of the co-axial structure including the IHX support structure may induce a severe thermal stress distribution. In this study, the structural feasibility of the current upper support structure concept is investigated through a preliminary stress analysis and an alternative design concept to accommodate the IHTS (Intermediate Heat Transport System) piping expansion loads and severe thermal stress is proposed. Through the structural analysis it is found that the alternative design concept is effective in reducing the thermal stress and acquiring structural integrity.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.12 no.1
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• pp.107-114
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• 2016

Four cylindrically shaped IHXs(Intermediate Heat Exchangers) are installed in the PHTS(Primary Heat Transfer System) of the PGSFR(Prototype Gen IV Sodium cooled Fast Reactor). As for the IHX, the temperature difference of structure is inevitable result caused by heat transfer between primary coolant sodium and IHTS(Intermediate Heat Transport System) sodium. It is necessary to evaluate the high temperature structural integrity of IHXs which operate at the elevated temperature condition over the creep temperature. In this paper, the high temperature structural integrity of IHX under assumed loading conditions has been reviewed according to ASME code.

• Archives of Pharmacal Research
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• v.16 no.1
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• pp.1-5
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• 1993

The reaction of sulfhydryl groups in human serum ablumin with bacteriostatic and hypotensive notrosating agents such as sodium nitorprusside and sodium nitrite has been examined. The low reactivity of sodium nitroprusside to sulfhydral groups in albumin has been observed and the sterical inaccessilibility of the agent site which sulfhydryl group resides was implicated. The reaction of sodium nitrite with albumin was highly influenced by pH and little reactivity was observed at physiological pH. On the other hand, the reaction between albumin and S-nitrosoglutatione, an intermediate induced from the reaction of glutathione and nitrosating agents, resulted in the rapid decrease of free sulfhydryl groups in albumin. S-Nitrosylation of the sulfhydryl group by S-nitrosoglutathione and the subsequent production of mixed disulfide is the probable route of modification. In the physiological system, S-nitroso-glutathione may act as an active intermediate in expressing reacivity of nitrosating agents to sulfhydryl groups in albumin.

• Korean Chemical Engineering Research
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• v.57 no.1
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• pp.28-41
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• 2019

We carried out performance analysis of Sodium-Water Reaction Pressure Relief System of Prototype Generation-IV Sodium-Cooled Fast Reactor. We analyzed transient-dynamic behavior of fluids inside the steam generator to vent into a sodium dump tank or a water dump tank when tubes in the steam generator were broken to cause a large-water-leak accident. Accordingly, we preliminarily evaluated design requirements of our system. Our results showed that sodium in the shell side of the steam generator and in Intermediate Heat Transport System was completely vented within 50 s and feed water in the tube side of the steam generator was completely vented within 2.5 s. It was analyzed that pressure of the tube side of the steam generator was higher than pressure of the shell side of the steam generator, which showed that sodium in the shell side did not flow into the tube side. Our results are expected to be used as basis information to performance analysis of Sodium-Water Reaction Pressure Relief System of Prototype Generation-IV Sodium-Cooled Fast Reactor.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.285-290
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• 2007

KALIMER-600 is a sodium cooled fast reactor with a fast spectrum neutron reactor core. The NSSS design has three heat transport systems of a PHTS (Primary Heat Transport System), a IHTS (Intermediate Heat Transport System) and a SGS (Steam Generation System). PHTS is a pool type and has a large amount of sodium in the pool. The mechanical design targets are maintaining the enough structural integrity for a seismic load of SSE 0.3g and the thermal and mechanical loads by the high temperature environments and an economical competitiveness when compared with other reactor types.

• Nuclear Engineering and Technology
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• v.41 no.8
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• pp.1115-1126
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• 2009

As one of the ways to enhance the economical features in sodium-cooled fast reactor development, the concept of an integrated steam generator and pump system (ISGPS) is proposed from a structural point of view. And the related intermediate heat transfer system (IHTS) piping layout compatible with the ISGPS is described in detail. To assure the creep design lifetime of 60 years, the structural integrity is investigated through high temperature structural evaluation procedures by the SIE ASME-NH computer code, which implements the ASME-NH design rules. From the results of this study, it is found that the proposed ISGPS concept is feasible and applicable to a commercial SFR design.

• Analytical Science and Technology
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• v.30 no.3
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• pp.154-158
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• 2017

The Korean Pharmacopoeia (KP XI), British Pharmacopoeia (BP 2013) and Japanese Pharmacopoeia contain monographs for the quality control of raw fusidate sodium and its formulations using high performance liquid chromatography (HPLC). However, the assay method for the determination of fusidate sodium in commercial tablets is titration which is less specific than HPLC. In this study, we present an alternative HPLC method for quantitation of fusidate sodium in tablets. Method validation was performed to determine linearity, precision, accuracy, system suitability, and robustness. The linearity of calibration curves in the desired concentration range was high ($r^2=0.9999$), while the RSDs for intra- and inter-day precision were 0.25-0.37 % and 0.11-0.60 %, respectively. Accuracies ranged from 99.46-100.85 %. Since the system suitability, intermediate-precision and robustness of the assay were satisfactory, this method will be a valuable addition to the Korean Pharmacopoeia (KP XI).

• Nuclear Engineering and Technology
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• v.48 no.4
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• pp.952-964
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• 2016

The prototype generation IV sodium-cooled fast reactor (PGSFR) has been developed by the Korea Atomic Energy Research Institute. This reactor uses sodium as a reactor coolant to transfer the core heat energy to the turbine. Sodium has chemical characteristics that allow it to violently react with materials such as a water or steam. When a sodium-water reaction (SWR) occurs due to leakage or breakage of steam generator tubes, high-pressure waves and corrosive reaction products are produced, which threaten the structural integrity of the components of the intermediate heat-transfer system (IHTS) and the safety of the primary heat-transfer system (PHTS). In the PGSFR, SWR events are included in the design-basis event. This event should be analyzed from the viewpoint of the integrities of the IHTS and fuel rods. To evaluate the integrity of the IHTS based on the consequences of the SWR, the behaviors of the generated high-pressure waves are analyzed at the major positions of a failed IHTS loop using a sodium-water advanced analysis method-II code. The integrity of the fuel rods must be consistently maintained below the safety acceptance criteria to avoid the consequences of the SWR. The integrity of the PHTS is evaluated using the multidimensional analysis of reactor safety-liquid metal reactor code to model the whole plant.