• BMB Reports
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• 제51권7호
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• pp.327-337
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• 2018

Lamin A and its alternative splicing product Lamin C are the key intermediate filaments (IFs) of the inner nuclear membrane intermediate filament. Lamin A/C forms the inner nuclear mesh with Lamin B and works as a frame with a nuclear shape. In addition to supporting the function of nucleus, nuclear lamins perform important roles such as holding the nuclear pore complex and chromatin. However, mutations on the Lamin A or Lamin B related proteins induce various types of human genetic disorders and diseases including premature aging syndromes, muscular dystrophy, lipodystrophy and neuropathy. In this review, we briefly overview the relevance of genetic mutations of Lamin A, human disorders and laminopathies. We also discuss a mouse model for genetic diseases. Finally, we describe the current treatment for laminopathies.

• ETRI Journal
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• 제11권4호
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• pp.75-83
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• 1989

The diffusion mechanism of Si in GaAs was investigated using different diffusion sources based on the Si-Ga-As ternary phase equilibria. The Si profiles are measured with secondary ion mass spectrometry and differ significantly for sources taken from the different phase fields in the ternary phase diagram. Neutral As vacancy diffusion is proposed for acceptor Si diffusion anneals using a Ga - Si - GaAs source. Donor Si diffusion using As - rich sources and a Si -GaAs tie line source shows concentration dependent diffusion behavior. Concentration dependent diffusion coefficients of donor Si for As - rich source diffusion were found to be related to net ionized donor concentration and showed three regimes of different behavior: saturation regime, intermediate regime,and intrinsic regime. Ga vacancies are proposed to be responsible for donor Si diffusionin GaAs: $Si_Ga^+V_Ga^-$ (donor Si -acceptor Gavacancy) complex for the extrinsic regime and neutral $V_G$a, for the intrinsic regime.The Si - GaAs tie line source resulted in two branch profiles, intermediate between the As - rich and the Ga - rich source diffusion cases.

• 제어로봇시스템학회논문지
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• 제8권10호
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• pp.874-880
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• 2002

A number of techniques have been proposed for 3D display using view-difference of two eyes. These methods do not express enough reality like real world. The display images have to change according to the position of a viewer to improve reality. In this paper, we present an approach for generating intermediate image between two different view images by applying new image interpolation algorithm The interpolation algorithm is designed to cope with complex shapes. The proposed image interpolation algorithm generates rotated image about vertical axes by any angle from base images. Each base image that was obtained from CCD camera has an view-angle difference of $3^{\circ}C$, $5.5^{\circ}C$, $^{\circ}C$, $22^{\circ}C$, and $45^{\circ}C$. The proposed into mediate image generation method uses the geometric analysis of image and depth information through the block-based matching method.

• 한국통신학회논문지
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• 제30권9C호
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• pp.913-921
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• 2005

일반적인 bandpass sampling 방법인 real bandpass sampling 기법은 하향변환(downconversion)을 시행할 때 음의 주파수 대역의 RF 신호와의 에일리어싱(aliasing) 현상을 피해야 하므로 신중한 sampling 주파수 선택이 요구된다. 더욱이 다중신호(multiple signals)가 하향변환 될 경우에 이 sampling 방법은 더욱 많은 제약이 따르게 된다. 그러나 Hilbert 변환을 사용하는 complex bandpass sampling 방법은 음의 주파수 영역의 신호를 제거함으로써, real bandpass sampling 기법보다 유연하고 넓은 sampling 주파수 범위를 제공하며, 또한 더욱 낮은 sampling 주파수를 얻을 수 있는 장점이 있다. 본 논문에서는 이러한 complex bandpass sampling의 특징을 사용하여, 다중 신호를 하나의 통신 기기에서 동시에 하향 변환하는 수신기의 구조를 제시한다. 그리고 하나 또는 2개 신호의 하향변환에 관한 내용으로 제한하지 않고 N개의 신호로 확장하여 유효 sampling 주파수 영역 및 보호대역(guard-band)이 고려된 sampling 가능 최소 주파수에 관한 수식들을 일반화한다. 또한 모의실험을 통해 유도된 수식들을 증명한다.

• 대한화학회지
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• 제55권3호
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• pp.346-353
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• 2011

7-hydroxy-2H-chromen-2-one(HC)와 7-hydroxy-2H-chromen-2-one-4-acetic acid(HCA)의 염기성 가수분해반응을 aqueous-methanol과 aqueous-acetone 혼합물에서 283 K에서 313 K의 온도 범위에서 속도론적으로 연구하였다. 반응의 활성화 파라미터를 구하고 토의하였다. 게다가, 물, 물-에탄올, 물-아세톤 혼합물 내에서 화합물들에 대한 활성화 에너지 장벽의 변화를 속도론적 데이터로부터 추정하였다. 활성화 장벽의 변화는 HC and HCA의 가수분해 반응과 거의 같았다. HC와 HCA의 염기성 가수분해는 $k_{obs}=k_2[OH^-]$와 같은 속도법칙을 따른다. 메탄올 또는 아세톤의 비가 증가함에 따라 HC 와 HCA의 속도 상수들이 감소하는 것은 $OH^-$ 이온이 불안정해지기 때문이다. 활성화 엔트로피가 큰 음의 값을 갖는 다는 것은 반응이 중간 착물의 형성을 경유하며 진행된다는 것을 의미하며, 또한 중간 착물이 경직성과 안정도를 갖는다는 것을 의미한다. 그러므로, 중간 착물의 고리 열림이 속도 조절 단계가 될 것이다.

• 한국군사과학기술학회지
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• 제3권1호
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• pp.164-175
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• 2000

Three compounds of Cu(II)-loaded N,N,N'-trimethylethylenediaminated Merrifield-type polymers were synthesized with yields higher than 80%, and the hydrolysis reaction rates of O-isopropylmethyl-phosphonofluoridate(GB) and O-pinacolylmethylphosphonofluoridate (GD) catalyzed by them have been surveyed. GB and GD hydrolysis by Cu(II)-loaded polymers occurs via intermediate complex mechanism where rapid equilibrium to form intermediate complex between substrate and Cu(II)-loaded polymers($K_f$) is followed by rate determining hydrolysis step($k_1$). The measured activation parameters for $k_1$ are ${\Delta}H^{\ddag}$ : $17.75{\pm}0.98kJ/mol$ ${\Delta}S^{\ddag}$ / : $-218.42{\pm}3.35J/mol$ K, $E^{\circ}_a$ : $20.22{\pm}0.98kJ/mo1$ for GB and ${\Delta}H^{\ddag}$ / : $11.16{\pm}1.15kJ/mol,$${\Delta}S^{\ddag}$ /: $-258.57{\pm}3.93J/mol$ K, $E^{\circ}_a$ : $13.64{\pm}1.15 kJ/mol$ for GD. Standard enthalpy/entropy changes corresponding to the intermediate complex formation constant $K_f$ are ${\Delta}H^{\circ}$ : $37.05{\pm}2.19 kJ/mo1,$$ {\Delta}S^{\circ}$ : $163.12{\pm}7.49 J/mol$ K and ${\Delta}H^{\circ}$ : 418.59{\pm}2.04 kJ/mol,$ ${\Delta}S^{\circ}$ : 4111.92{\pm}6.98 J/mol$ K for GB and GD, respectively, The electron push-pull mechanism by Cu(II)-loaded polymers lowers the P-F bond breaking energy(~400 kJ/mol) to less than 1/20 compared to the case in which no Cu(II)-loaded resin presents. Analysis of $K_f$ and 4k_1$ over pH=6.5~8.0 range suggest that the GB and GD hydrolysis occurs intramolecularily with $pK_a$ =7.29 for ligated $H_2O$ and $t_{1/2}$=36.9 sec, $pK_a$ = 7.06 and $t_{1/2}$=177.7 sec for GB and GD, respectively.

• 한국컴퓨터정보학회논문지
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• 제14권1호
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• pp.217-228
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• 2009

데이터에 내재되어 있는 특이 패턴을 찾고자 데이터 분석을 할 때에 보통 다차원적인 데이터 집계를 하는데, 이때에 표준 SQL 쿼리를 사용해도 좋지만 쿼리가 아주 복잡해진다는 단점이 생기게 된다. 쿼리가 복잡해지면 표준 테이블을 여러 번 참조해야 되고 결과적으로 쿼리의 성능이 저하된다는 뜻이다. OLAP 쿼리는 복잡한 것이 대다수이기 때문에 SQL 쿼리를 대신할 새로운 집계용 연산자인 데이터 큐브를 간단히 불러 큐브를 만들 필요가 생기는 것이다. 집계를 하고, 부분 합을 구하는 것과 같은 OLAP 업무를 지원해 주는 것이 데이터 큐브이다. 이러한 데이터 큐브를 작성하는데 관련된 집계함수에는 여러 가지가 있는데, 이를 분배적 함수, 대수적 함수 그리고 전체관적 함수의 3가지로 분류할 수 있다. 이 중, SUM, COUNT, MAX, MIN과 같은 분배적 함수는 데이터 큐브를 작성하는 데에 직접사용 할 수 있고, AVG와 같은 대수적 함수는 매개함수를 활용하면 사용가능 하다고 알려져 있다. 즉, AVG 자체는 분배적 함수가 아니지만, (SUM, COUNT)와 같은 매개함수로 분배적 함수가되기 때문에 매개함수를 이용하여 구하면 된다는 뜻이다. 그러나 본 연구에서는 (SUM, COUNT)와 같은 매개함수를 통해 AVG를 구하는 것이 OLAP 큐브 작성에 적용시킬 수 없다는 사실을 확인했으며, 결과적으로 이 매개함수를 활용하면 잘못된 결론에 다다르고 그릇된 의사결정을 하게 된다는 사실을 확인하게 되었다. 따라서 본 연구에서는 집계함수 AVG를 OLAP 큐브에 적용시켰을 때의 여러 문제점을 밝혀내고 또한 이들 문제점을 해결할 방안을 찾고자 하는 데에 목적을 두고 있다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권9호
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• pp.4307-4325
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• 2016

With the aim of solving the problems of long processing times, high memory consumption and low event throughput in the current processing approaches in out-of-order RFID event streams, an efficient complex event processing method based on INFA-HTS (Improved Nondeterministic Finite Automaton-Hash Table Structure) is presented in this paper. The contribution of this paper lies in the fact that we use INFA and HTS to successfully realize the detection of complex events for out-of-order RFID event streams. Specifically, in our scheme, to detect the disorder of out-of-order event streams, we expand the traditional NFA model into a new INFA model to capture the related RFID primitive events from the out-of-order event stream. To high-efficiently manage the large intermediate capturing results, we use the HTS to store and process them. As a result, these problems in the existing methods can be effectively solved by our scheme. The simulation results of our experiments show that our proposed method in this paper outperforms some of the current general processing approaches used to process out-of-order RFID event streams.

• Human Ecology Research
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• 제56권4호
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• pp.331-345
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• 2018

This study explored the sandplay therapy case of a woman with a negative mother complex who wants to be free from family life. The goal of the therapy was to make her free from family life by expressing repressed emotions for getting out of a negative mother complex under a free and protected space in sandplay therapy. Twenty-three therapy sessions were held. The client exhibited a singing woman in a gorgeous dress and things she wanted to do in the initial phase of therapy (1-4, forgotten myself). In the intermediate phase of therapy (5-15, differentiation and integration), she displayed the scenes of differentiation and integration by emotionally getting rid of a begging boy and making mandalas. In the final phase of therapy (16-23, recovered myself), she showed scenes of rebirth, upgrading and singing songs again in front of family members and many people. Through sandplay therapy in the free and protected space, this study showed the effectiveness of sandplay therapy since the client achieved individuation by showing rebirth, having a new personality.

• The Korean Journal of Ecology
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• 제19권3호
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• pp.201-207
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• 1996

Selection of Al tolerant woody plants, and possibility of reforestation with the Al tolerant plants in soil conditions with different Al content, topography and slope exposures were studied on the slopes around Yeocheon Industrial Complex. Root growth in length of plants grown in 1/2 Steinberg solution decreased with increased Al concentrations of the solution. Relative root length showed that Paulownia coreana, Celtis sinensis and Firmiana simplex were sensitive to $500\muM$ Al, Pinus koraiensis, Alnus japonica and Ligustrum japonicum were intermediate, and Pinus rigida, P. densiflora and P. thunbergii were tolerant to $1, 000\muM$ Al. Coniferous plants appeared to be more tolerant to Al than deciduous ones. Soil pH was 4.2 and Al content was 509 ppm in average around the Yeocheon industrial complex. Al content and soil acidity were more deteriorated on the foothill and slope facing to the pollution source from the industrial complex than on the ridge and opposite slope.