• Journal of Distribution Science
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• v.10 no.5
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• pp.45-55
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• 2012

In Korea, the parcel delivery service was launched officially in 1992, and the market has grown to 13.2 billion units, or 3.5 trillion won, as of 2011. The service companies accept small packages under 30 kg and deliver them on the next day in most domestic areas. This service plays an important role in business and personal activities. The parcel service companies have themselves designed the tariff for the delivery service based on two criteria: weight and the sum of three side lengths. Further, the tariff is graded in steps of three or four rate structures based on size (small, medium, large, and extra-small). However, the basic freight rate is generally decided according to the cargo's weight or measurement size, and an extra rate is added according to some factors (handling, stowability, liability, and so on). The parcel service tariff adopted by the companies is illogically designed, and this study was carried out to assess the need for redesigning the tariff structure. The cargo volume cannot be logically reflected by three side lengths. For example, two parcels measuring 160 cm based on three side lengths may have different volumes, one measuring 0.152 cbm (53.33 cm × 53.33 cm × 53.34 cm) and the other 0.05 cbm (100 cm × 50 cm × 10 cm). A small package of less than120 cm (sum of three side lengths) may have a volume of as much as 0.064 cbm (40 cm × 40 cm × 40 cm). Sample comparison showed that 17% of medium-size parcels (based on the sum of three side lengths) are small-volume packages, 24% of large-size parcels are small- or medium-volume packages, and 40% of extra-big-size parcels are big- or under-size packages. Therefore, if parcel service companies rate their services for volume cargo based on the three side lengths standard, users may have to pay higher than normal rates, particularly because a large percentage of parcels are volume cargo. According to this study, the average weight per 1 cbm is less than 300 kg. Therefore, users face an increasing risk of paying higher than logical freight charges. Generally, transportation companies are called "public interest enterprises," and parcel service companies operate as postal services. Public interest enterprises must provide the delivery service to all customers without discrimination at a reasonable service level and logical service charges. Therefore, parcels service tariffs must be designed and adopted logically. In this study, freight theories and prior research findings were used to consider the importance of freight rates, and distortion of parcel service rates based on the three side lengths system was verified through regression analysis of a parcel sample and sample comparison. In conclusion, volume sizes based on three side lengths have a higher correlation to the rate level than does the sum of three side lengths. Further, compared to the sum of three side lengths, volume size has a higher correlation to cargo weight, which is the most basic factor determining transportation cost. Therefore, the existing parcel service tariff should be changed to weight- and volume-based rates, and the tariff must be graded in steps of 8 to 10 higher rate structures for a logical freight schedule based on service cost.

• Clinical and Experimental Pediatrics
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• v.57 no.10
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• pp.434-439
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• 2014

Treatment outcomes of pediatric cancers have improved greatly with the development of improved treatment protocols, new drugs, and better supportive measures, resulting in overall survival rates greater than 70%. Survival rates are highest in acute lymphoblastic leukemia, reaching more than 90%, owing to risk-based treatment through multicenter clinical trials and protocols developed to prevent central nervous system relapse and testicular relapse in boys. New drugs including clofarabine and nelarabine are currently being evaluated in clinical trials, and other targeted agents are continuously being developed. Chimeric antigen receptor-modified T cells are now attracting interest for the treatment of recurrent or refractory disease. Stem cell transplantation is still the most effective treatment for pediatric acute myeloid leukemia (AML). However, in order to reduce treatment-related death after stem cell transplantation, there is need for improved treatments. New drugs and targeted agents are also needed for improved outcome of AML. Surgery and radiation therapy have been the mainstay for brain tumor treatment. However, chemotherapy is becoming more important for patients who are not eligible for radiotherapy owing to age. Stem cell transplant as a means of high dose chemotherapy and stem cell rescue is a new treatment modality and is often repeated for improved survival. Drugs such as temozolomide are new chemotherapeutic options. In order to achieve 100% cure in children with pediatric cancer, every possible treatment modality and effort should be considered.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.19 no.3
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• pp.14-27
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• 2020

Pedestrian deaths account for a high percentage of deaths in traffic accidents in Korea, raising interest in pedestrian safety policy. However, since the walk signal time is applied based on the length of the crosswalk without considering the walker and the signal cycle, the walk waiting time is relatively longer than the crosswalk, causing pedestrian jaywalking. In this study, due to an unreasonable signal time plan during a road crossing where a signal is installed, the pedestrian's walk signal was given twice a cycle of crossings, and the operational and safety effects of the signal system were quantitatively and qualitatively analyzed, and the operational effects of the signal interval and jaywalking rate were assessed by different signal intervals. The results showed that jaywalking and waiting time decreased, and the shorter the interval between the application of the walk signal time, the less jaywalking is analyzed. However, there is a risk of vehicle conflict due to pedestrian exposure, and measures for expanding safety for operation were proposed.

• International Commerce and Information Review
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• v.14 no.3
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• pp.31-47
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• 2012

The Eurozone was launched to set a goal on using the single currency perfectly in 1999. Using the Euro could get rid of exchange cost and cost of Foreign exchange risk management which was approximately 1% of each member's GDP. It was possible that members has maintained a stable level of inflation and stimulate investment and employment with low interest rate. In addition, they could lead to economic growth and investment as well as increase the Euro demand in financial market. Especially, members has used the Euro as the method of payment on trade each other so that the volume of trade among the Eurozone members has increased continuously which was called "the effect of single market." This paper analyzes the correlation between using the Euro and members' export/import by using random effect estimation and fixed effect estimation. As a result, Eurozone members can get export decreasing effect of 4.68% and import increasing effect of 10.5% respectively on average by using the Euro.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.57 no.10
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• pp.1893-1895
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• 2008

In this paper, we investigated the maximum ankle joint plantarflexion moment(MPM) of young and elderly subjects during various modes of isokinetic contractions with special interest in the elderly females who were reported to have higher fall rate than the elderly males. Subjects include the young subjects(14 males: $22.7{\pm}2.5yrs$, 13 females: $20.5{\pm}1.3yrs$) and the elderly subjects(17 males: $65.8{\pm}10.5yrs$, 26 females: $71.4{\pm}5.2yrs$). The MPM was normalized by each subject's body weight. The MPM of elderly females was the weakest among the groups, particularly, at the eccentric contractions. The male-to-female ratio of MPM was greater in the elderly than in the young and the young-to-elderly ratio of MPM was greater in female than in male, both during the eccentric contractions. The result suggests that the decreased muscle force per body weight, especially at the eccentric contraction, may be one reason for the more frequent fall of the elderly female than the elderly male.

• Journal of Technology Innovation
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• v.5 no.1
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• pp.206-222
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• 1997

The conventional analysis with which justifies government intervention of the private sector's innovation activities is the market failure approach. According to such analysis, fund allocation through autonomous market mechanisms is not optimal in technology financing because of the disparity between the desirable level of investment for society as a whole and that for private firms. To optimize the fund allocation, public policies such as subsidy, preferencial loan and venture capital investment programs are designed for technology development projects performed by private firms. They, however, have not been effective in increasing private investment for such projects. In most cases, it was found that little considerations given to the relationship between uncertainty embodied in technology development projects and each types of financing. With respect to optimizing fund allocation, technology development projects should be financed by different means according to their probability of success and the expected value of technology. Employing various theoretical models on financing decision-making we verify here that technology development projects to be supported by commercial banks or venture capital institutions is limited contingent upon levels of uncertainty adn expected value. Under the assumption that financial institutions are risk averse, loan or investment can be available only if the probability of success of the project is higher than the probability premium and the current market rate of interest. Therefore, the projects that have lower probability of success and/or small expected return are excluded from commercial loan or investment programs. However, the remaining projects, whose probability of success is low but with high expected return, may be applied under government subsidy programs. To achieve optimality of fund allocation and to activate technology financing, we conclude that there should be a systematic division of role among financial institutions including government commercial banks, and venture capital institutions.

• Journal of Digital Convergence
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• v.12 no.10
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• pp.271-282
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• 2014

Cloud computing technology will provide application that needs many resources and various services to customers without any restriction of time and place. So, many of companies are now adopting cloud computing technology to this business and this trend is now increasing. However, cloud technology adoption rate is low because of security, compatibility, loss of control, security, data protection, performance and uptime, to the risk of vendor lock-in Cloud computing services, and compatibility with existing systems and anxiety. Now, many people are interest on the migration of existing systems but there are many study on this issue. So, more of study on this issue should be needed. This paper will show you the method that how to adopt cloud computing to their business and also show you evolution of cloud computing for existing system.

• Journal of Microbiology and Biotechnology
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• v.31 no.4
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• pp.610-620
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• 2021

There has been increasing interest in the head and neck squamous cell carcinoma (HNSCC) that is caused by high-risk human papillomavirus (HR-HPV) and has posed a significant challenge to Otolaryngologists. A rapid, sensitive, and reliable method is required for the detection of HR-HPV in clinical specimens to prevent and treat HPV-induced diseases. In this study, a multiple cross-linking spiral amplification (MCLSA) assay was developed for the visual detection of HPV-16. In the MCLSA assay, samples were incubated under optimized conditions at 62℃ for 45 min, and after mixing with the SYBR Green I (SGI) dye, the positive amplicons showed bright green fluorescence while the negative amplicons exhibited no obvious change. The specificity test revealed that the developed MCLSA technique had high specificity and could effectively distinguish all five HPV-16 strains from other pathogenic microorganisms. In terms of analytical sensitivity, the limit of detection (LoD) of MCLSA assay was approximately 5.4 × 101 copies/tube, which was 10-fold more sensitive than loop-mediated isothermal amplification (LAMP) and RT-PCR. The detection results of laryngeal cancer specimens collected from 46 patients with suspected HPV infection in the Liaoning region demonstrated that the positive detection rates of MCLSA and hybridized capture 2 kit were 32.61% (15/46). The true positive rate of the MCLSA assay was higher than that of RT-PCR (100% vs. 93.33%) and LAMP (100% vs. 86.67%). Therefore, the MCLSA assay developed in the present study could be a potentially useful tool for the point-of-care (PoC) diagnosis of HR-HPV, especially in resource-limited countries.

• Journal of the Korea Convergence Society
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• v.10 no.8
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• pp.21-26
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• 2019

This paper proposes a fatigue recognition method using the C4.5 algorithm. Based on domestic and international studies on fatigue evaluation, we have completed the fatigue self - assessment scale in combination with lifestyle and cultural characteristics of Chinese people. The scales used in the text were applied to 58 sub items and were used to assess the type and extent of fatigue. These items fall into four categories that measure physical fatigue, mental fatigue, personal habits, and fatigue outcomes. The purpose of this study is to analyze the leading causes of fatigue formation and to recognize the degree of fatigue, thereby increasing the personal interest in fatigue and reducing the risk of cerebrovascular disease due to excessive fatigue. The recognition rate of the fatigue recognition system using the C4.5 algorithm was 85% on average, confirming the usefulness of this proposal.

• Journal of Korean Medicine for Obesity Research
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• v.19 no.1
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• pp.68-78
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• 2019

Objectives: The purpose of this review is to analyse the trend in papers related to obese people with disabilities. Methods: We reviewed Korean Medicine papers by searching 4 Korean web databases and classified the papers by the year of publishment, the title of journals, the type of study, main treatment, assessment for outcomes. Results: There were 18 studies about the intellectually disabled, which accounted for most of the study. It is expected that intensive research on obesity for the intellectually disabled will be conducted in the future. Also, study on obesity for the disabled will require special attention. Disabled person tend to have a higher obesity rate and secondary diseases due to disabilities can be easily developed. Their health care capabilities are more likely lower than those of the general population. Given these considerations, it would be necessary to study metabolic syndrome in parallel in the study of obesity for the disabled. Disabled person are exposed to obesity more easily than ordinary people, and there is a higher risk of health degradation due to complications from obesity, which requires more attention and research. However, since there is not research in the oriental medical and medical circles on obesity in the disabled, medical approaches and studies on obesity in the disabled are necessary. Conclusions: We expect that more interest and research will be carried out on obesity for the disabled in the Korean medicine to achieve clinical application and to develop treatment protocols for the disabled obesity disease.