• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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• pp.431-436
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• 2005

Living cells are sustained not by individual activities but rather by coordinated summative efforts of different biological functional modules. While recent research works have focused largely on finding individual functional modules, this paper attempts to explore the connections or relationships between different cellular functions through cross-function domain interaction maps. Exploring such a domain interaction map can help understand the underlying inter-function communication mechanisms. To construct a cross-function domain interaction map from existing genome-wide protein-protein interaction datasets, we propose a two-step procedure. First, we infer conserved domain-domain interactions from genome-wide protein-protein interactions of yeast, worm and fly. We then build a cross-function domain interaction map that shows the connections of different functions through various conserved domain interactions. The domain interaction maps reveal that conserved domain-domain interactions can be found in most detected cross-functional relationships and a f9w domains play pivotal roles in these relationships. Another important discovery in the paper is that conserved domains correspond to highly connected protein hubs that connect different functional modules together.

• 생명과학회지
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• 제14권6호
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• pp.997-1002
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• 2004

이 논문은 단백질의 기능분석을 위해 핵심적으로 요구되는 단백질 상호작용 관계정보 및 기능정보 등을 체계적으로 제공할 수 있는 WASPIFA (Web-based Assistant System for Protein-protein Interaction and function Analysis) 시스템에 대해서 다루고 있다. WASPIFA 시스템은 특정 분야에 국한해서 단편적 정보를 제공하는 기존의 단백질 기능 및 상호작용 분석 시스템과는 달리 분석하고자 하는 서열의 종합적인 정보 즉, 기능정보 및 주석정보, 도메인 정보, 상호작용 관계정보 등을 제공한다. 일반 검색 및 분석 시스템에서 제공하지 못하는 종합적인 정보들은 다양한 전처리 과정을 통해서 얻어진 데이터 및 정보 등을 시스템 내에 로컬 데이터베이스화해 놓은 것이다. 최종 사용자는 종합적인 정보를 통해서 올바른 평가와 판단을 통해서 효과적인 단백질 상호작용 분석과 기능분석을 행할 수 있다. 또한 자동관리 및 데이터 갱신 기능을 갖추고 있어 시스템 관리자가 효율적으로 시스템을 유지 및 관리할 수 있다.

• 한국콘텐츠학회논문지
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• 제6권2호
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• pp.93-98
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• 2006

본 논문은 컴포넌트 검색 시스템의 성능을 향상시키기 위해 사용자 피드백을 효율적으로 수행하는 방법을 제안하고자 한다. 기존의 퍼지 기법이 적용된 퍼지화 함수는 컴포넌트를 선택할 때마다 매번 4가지 경우의 그래프를 재구성해야 하는 어려움이 있다. 본 연구에서는 이러한 피드백의 단점을 극복하기 위하여 검색된 컴포넌트의 선택여부에 따라 동일한 함수이지만 학습률을 달리할 수 있는 가우시안 함수를 이용한 상호작용 함수를 제안한다. 가우시안 함수를 피드백 함수로 채택 시 함수의 파라메타에 따른 검색 성능을 비교하고, 이를 토대로 가장 효율적인 동적 상호작용 함수를 제안하여 효율적인 검색 시스템을 구축하고자 한다.

• Interaction and multiscale mechanics
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• 제5권3호
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• pp.287-318
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• 2012

We apply a partitioned-solution (iterative-staggered) coupling method based on a fixed Eulerian mesh with the level set function to a large-deformation fluid-structure interaction (FSI) problem where a large-deformable thin structure moves in a high-speed flow field, as an airbag does during deployment. This method combines advanced fluid and structure solvers-specifically, the constrained interpolation profile finite element method (CIP-FEM) for fluid Eulerian mesh and large-deformable structural elements for Lagrangian structural mesh. We express the large-deformable interface as a zero isosurface by the level set function, and introduce virtual nodes with level sets and structural normal velocities to generate the level set function according to the large-deformable interfacial geometry and enforce the kinematic condition at the interface. The virtual nodes are located in the direction normal to the structural mesh. It is confirmed that application of the method to unfolded airbag deployment simulation shows the adequacy of the method.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제19권2호
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• pp.147-169
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• 2012

We introduce a Heaviside-function formulation of the interaction between incompressible two-phase fluid and a non-deformable solid. Fluid and solid interact in two ways : fluid satises the Dirichlet boundary condition imposed by the velocity field of solid, and solid is accelerated by the surface traction exerted by fluid. The two-way couplings are formulated by the Heaviside function to the interface between solid and fluid. The cumbersome treatment of interface is taken care of by the Heaviside function, and the interaction is discretized in a simple manner. The discretization results in a stable and accurate projection method.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2009년도 춘계학술대회 논문집 특별세미나,특별/일반세션
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• pp.359-366
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• 2009

This paper aims for analyzing the vibration serviceability of train by simply expressing its vertical vibration when it passes a railway bridge. For this purpose, bridge-train transfer function was derived and bridge-train interaction analysis was performed by using the derived function. The bridge-train transfer function was developed with the assumption that train is a single mass-spring system, and bridge-train interaction analysis was performed on simple beams of KTX passenger car. The vertical acceleration signals of passenger cars obtained from bridge-train interaction analysis were compared with them of cars obtained from the bridge-train transfer function. As a result, it could be estimated to express the vertical vibration inside the passenger car required for vibration serviceability evaluation by using the vertical vibration of bridges obtained from moving load analysis. Therefore, it may be possible to evaluate the vibration serviceability of railway bridges considering bridge-train interaction effect.

• 한국멀티미디어학회논문지
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• 제8권5호
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• pp.670-678
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• 2005

셀룰라 오토마타(CA, Cellular Automata)란 동역 학계 (Dynamical Systems)를 해석하는 한 방법으로 공간과 시간을 이산적으로 다루고 셀룰라 공간(Cellular Space)의 기본 단위인 각 셀(Cell)이 취할 수 있는 상태를 유한하게 처리하며, 각 셀의 상태가 국소적인 상호작용(Local Interaction)에 의해서 동시에 갱신되는 시스템이다. CA는 그 본질적 인 특성 이 확산(Diffusion)과 국소적 인 상호 작용(Local Interaction)이므로 암호 시스템과 VLSI환경에 적합한 것으로 알려져 있다. 본 연구에서는 새로운 구조의 이차원 셀룰라 오토마타를 제안하고 제안된 이차원 셀룰라 오토마타에 기초한 새로운 구조의 해쉬 함수를 제안하고 제안된 해쉬 함수의 통계적 검증 결과를 밝힌다. 또한 제안된 해쉬 함수는 키를 사용하는 경우와 그렇지 않은 경우에 모두 적용 가능하도록 구성되었다.

• 대한물리의학회지
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• 제5권4호
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• pp.645-654
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• 2010

Purpose : The purpose of this study was to investigate changes in the gross motor function, self-esteem and social ability of children with cerebral palsy from group exercise program for physical and emotional interaction. Methods : Five cerebral palsy children who live in U city were recruited this study. Exercise sessions were held for 1 hour per session, once per week, for 12 consecutive weeks. At pre-treatment and post-treatment, subject were tested gross motor function measure, self-esteem and social ability. Results : After 12 weeks of paticipation in the group exercise program for physical and emotional interaction, there were improvements for gross motor function measure, self-esteem and social ability. Conclusion : Group exercise program for physical and emotional interaction can improve gross motor function, self-esteem and social ability.

• 한국신뢰성학회지:신뢰성응용연구
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• 제17권1호
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• pp.28-37
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• 2017

Purpose: This paper proposes a procedure that may infer and identify interaction failures in a module. Methods: In design FMEA, we defined an interaction model between components and proposed a method for selecting a single component by using the standard specification classification table and four methods for choosing the related components. We also introduced the function tree for function and requirement characteristic analysis and proposed utilization of standard stress lists and 1st and 2nd stress analysis tables to determine the effect the stress analysis has on interactions. Finally, the interaction mechanism diagram was proposed and used to infer the failure mechanism. Process FMEA also established procedures in a similar way. Results: We established a procedure for predicting the failure mode due to interaction between components based on Company A's multi-step FMEA procedure. Conclusion: By applying the proposed interaction FMEA procedure to the development model, we were able to confirm the effect of the new derivation on the failure mode of interaction, which was not predicted by the existing FMEA.

• Bulletin of the Korean Chemical Society
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• 제34권12호
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• pp.3727-3732
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• 2013

The interaction between metalloporphyrins and diazine tautomers was investigated using quantum chemistry method. The results showed that the metal atom in the metalloporphyrin was not coplanar with porphin ring, and zinc porphyrin has the most extent of its non-coplanar nature. The most stable complex in nine complexes was iron porphyrin. NBO analysis indicated that the interaction between the lone pair of electrons on the nitrogen atom and the unoccupied lone pair orbital of metal contributes significantly to the stability of the complexes. Through the conceptual DFT parameter and Fukui dual descriptor, the thermodynamic stability and reactivity of complexes were analyzed. The density difference function (DDF) analyzes were performed to explore the rearrangement of electronic density after the coordination interaction. NICS calculation indicated that metalloporphyrin aromaticity was reduced after the coordination interaction, and aromaticity of diazine tautomer was increased along direction vector of the coordination interaction force.