• Interdisciplinary Bio Central
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• 제3권2호
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• pp.8.1-8.6
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• 2011

Background: Thanks to the development of the mathematical/statistical reverse engineering and the high-throughput measuring biotechnology, lots of biologically meaningful genegene interaction networks have been revealed. Steady-state analysis of these systems provides an important clue to understand and to predict the systematic behaviours of the biological system. However, modeling such a complex and large-scale system is one of the challenging difficulties in systems biology. Results: We introduce a new stochastic modeling approach that can describe gene regulatory mechanisms by dividing two (DNA and protein) layers. Simple queuing system is employed to explain the DNA layer and the protein layer is modeled using G-networks which enable us to account for the post-translational protein interactions. Our method is applied to a transcription repression system and an active protein degradation system. The steady-state results suggest that the active protein degradation system is more sensitive but the transcription repression system might be more reliable than the transcription repression system. Conclusions: Our two layer stochastic model successfully describes the long-run behaviour of gene regulatory networks which consist of various mRNA/protein processes. The analytic solution of the G-networks enables us to extend our model to a large-scale system. A more reliable modeling approach could be achieved by cooperating with a real experimental study in synthetic biology.

• 조명전기설비학회논문지
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• 제25권8호
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• pp.30-38
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• 2011

This paper proposes a new intelligent diagnosis equipment for the partial discharge, which keeps deteriorating the insulating materials inside electric machineries, ultimately leading to electrical breakdown. In order to simulate experimentally the partial discharge inside the electric machinery, the tip-to-plate, the sphere-to-plate, the sphere-to-sphere and the plate-to-plate electrodes are used respectively, of which the gaps are 1[mm], 3[mm] or 5[mm] and the applied voltages are 3[kV], 5[kV] or 7[kV]. Ceramic coupler sensor and FIR digital filter are used to measure the partial discharge and the artificial neural network is used for the deterioration diagnosis of the electric machinery. The microprocessor of PD diagnosis equipment is DSP (TMS320C6713) with FPGA (Cyclone II). The results of the real-time and on-line experiments performed with the developed equipment are also explained.

• 한국지능시스템학회논문지
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• 제14권7호
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• pp.914-919
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• 2004

모터가 회전할 때 감속기에 연결되어 있는 구동부의 부하나 구동부의 상태변화에 따라 모터의 토크, 회전수 등이 함께 변한다. 역으로 모터의 토크, 회전수 등을 측정하면 부하의 변동이나 구동부의 상태를 감시 할 수 있다. 이를 위해 스트레인게이지와 브릿지회로를 이용한 토크측정방법이 가장 일반적인데 이것은 접촉식 방법이어서 회전 속도와 사용시간에 따른 수명을 가진다. 그래서 이 방법을 이용한 시스템은 부품의 일부 또는 전체를 교체하는 유지보수론 필요로 하게 된다. 그리고 이러한 장비는 크기가 크고 고가이며 계측기를 연결하고 측정하는 과정이 매우 번거롭다. 본 논문에서 우리는 홀 이펙터 센서를 이용하여 토크와 회전수를 측정하는 비 접촉식 방법을 제안하고자 한다. 이를 위해서 홀 센서를 유성기어에 부착하고 이를 이용한 기어드 모터와 모니터링 시스템을 제작하였다. 모니터링 시스템은 측정 데이터(토크, 회전수)와 연산되어진 데이터(전달 동력)를 화면표시하며 블루투스 통신 프로토콜을 이용한 네트워킹 기능을 가진다. 제안된 방법은 기존방법에 비해 매우 저렴한 방법이고 토크와 회전수를 측정하는 매우 간단한 방법이다.

• 한국지능시스템학회논문지
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• 제14권1호
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• pp.57-62
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• 2004

본 논문에서는 연결 성분간의 공간적 간격에 기반하여 수표 영상 내의 필기체 문장 금액에서 단어를 효율적으로 추출하기 위한 방법을 제안한다. 인접한 연결 성분간의 거리측정을 위한 기존의 방식들은 과대추정 또는 과소추정 문제로 인한 단어 분리 오류를 초래할 수 있으나 본 논문에서는 이러한 문제를 줄이기 위해 각 측정 방식들을 수정 보완하였다. 또한 본 논문에서는 서로 다른 형태의 세 가지 거리 측정법들을 효과적으로 결합하여 각 개별 측정법이 가지는 단점을 상호 보완하고 전체 단어 추출 성능을 좀더 향상시킬 수 있는 4-클래스 군집화에 기반한 결합 방법을 새로이 제안하였다. 분장 금액에 대한 단어 추출 실험 결과로부터 수정된 각 거리 측정법이 대응되는 기존의 측정법에 비해 2-3% 정도 향상된 단어 분리율을 보임을 확인하였다. 또한 제안된 4-클래스 군집화에 기반한 결합 방식은 각 측정 방식에서 개별적으로 발생하는 에러뿐만 아니라 두 개의 방식에서 동시에 나타나는 에러도 효율적으로 감소시킴으로서 전체 단어 분리 성능을 향상 시킬수 있었다.

• 한국지능시스템학회논문지
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• 제22권3호
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• pp.287-293
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• 2012

본 논문에서는 영상의 다차원 명암도 증감에 기반을 둔 유사도 측정에 의한 효율적인 영상정합 방법을 제안하였다. 여기서 다차원 명암도는 영상의 4방향을 고려한 유사성 판정으로 영상이 가지는 속성을 더욱 더 많이 반영하기 위함이고, 명암도 증감은 인접 픽셀간의 밝기변화를 고려함으로써 좀 더 포괄적으로 유사성을 측정하기 위함이다. 또한 측정된 4방향 각각의 명암도 증감에 대한 정규상호상관계수를 구하고, 그 각각에 바탕을 둔 전체 정규상호상관계수, 각 방향의 상관계수에 대한 산술평균과 단순 곱 및 최대값으로 정규화된 상관계수의 산술평균과 단순 곱으로 정의된 유사도 계수로 각각 정합을 측정하였다. 제안된 방법을 22개의 243*243 픽셀 얼굴영상과 9개의 500*500 픽셀 인물영상을 대상으로 각각 실험한 결과, 영상의 속성을 잘 반영한 우수한 정합성능이 있음을 확인하였다. 특히 각 방향의 상관계수에 대한 산술평균 유사도가 가장 우수한 신뢰성을 가지는 정합척도임을 알 수 있었다.

• 분석과학
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• 제34권5호
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• pp.193-201
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• 2021

We have demonstrated a sensitive analytical method of measuring oleracone D in mouse plasma using a liquid chromatography-tandem mass spectrometry (LC-MS/MS). Oleracone D and oleracone F (internal standard) in mouse plasma samples were processed using a liquid-liquid extraction method with methyl tertbutyl ether, resulting in high and reproducible extraction recovery (80.19-82.49 %). No interfering peaks around the peak elution time of oleracone D and oleracone F were observed. The standard calibration curves for oleracone D ranged from 0.5 to 100 ng/mL and were linear with r² of 0.992. The inter- and intra-day accuracy and precision and the stability fell within the acceptance criteria. The pharmacokinetics of oleracone D following intravenous and oral administration of oleracone D at doses of 5 mg/kg and 30 mg/kg, respectively, were investigated. When oleracone D was intravenously injected, it had first-order elimination kinetics with high clearance and volume of distribution values. The absolute oral bioavailability of this compound was calculated as 0.95 %, with multi-exponential kinetics. The low aqueous solubility and a high oral dose of oleracone D may explain the different elimination kinetics of oleracone D between intravenous and oral administration. Collectively, this newly developed sensitive LC-MS/MS method of oleracone D could be successfully utilized for investigating the pharmacokinetic properties of this compound and could be used in future studies for the lead optimization and biopharmaceutic investigation of oleracone D.

• 로봇학회논문지
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• 제17권2호
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• pp.142-151
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• 2022

With the advent of the 4th industrial revolution, autonomous driving technology is being commercialized in various industries. However, research on autonomous driving so far has focused on platforms with wheel-type platform. Research on a tracked platform is at a relatively inadequate step. Since the tracked platform has a different driving and steering method from the wheel-type platform, the existing research cannot be applied as it is. Therefore, a path-tracking algorithm suitable for a tracked platform is required. In this paper, we studied a path-tracking algorithm for a tracked platform based on a GPS sensor. The existing Pure Pursuit algorithm was applied in consideration of the characteristics of the tracked platform. And to compensate for "Cutting Corner", which is a disadvantage of the existing Pure Pursuit algorithm, an algorithm that changes the LAD according to the curvature of the path was developed. In the existing pure pursuit algorithm that used a tracked platform to drive a path including a right-angle turn, the RMS path error in the straight section was 0.1034 m and the RMS error in the turning section was measured to be 0.2787 m. On the other hand, in the variable LAD algorithm, the RMS path error in the straight section was 0.0987 m, and the RMS path error in the turning section was measured to be 0.1396 m. In the turning section, the RMS path error was reduced by 48.8971%. The validity of the algorithm was verified by measuring the path error by tracking the path using a tracked robot platform.

• Nuclear Engineering and Technology
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• 제55권9호
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• pp.3260-3267
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• 2023

Zr-Nb alloy have been widely used as fuel rods in nuclear power plants. However, from the Fukushima nuclear accident, the weakness of the rod was revealed under harsh conditions, and research on the safety of these types of rods was conducted after the disaster. The method of depositing chromium onto the existing Zr-Nb alloy fuel rods is being considered as a means by which to compensate for the weakness of Zr-Nb alloy rods because chromium is strong against oxidation at high temperatures and has high strength. In order to secure these advantages, it is important to maintain the Cr thickness of the rods and properly inspect the rods before and during their use in power generation. Eddy current testing is a typical means of evaluating the thickness of thin metals and detecting surface defects. Depending on the size and shape of the inspected object, various eddy current sensors can be applied. In particular, because pancake sensors can be manufactured in very small sizes, they can be used for inspections even in narrow spaces, such as a nuclear fuel assembly. In this study, an eddy current technique was developed to confirm the feasibility of Cr coating thickness evaluations. After determining the design parameters of the pancake sensor by means of a FEM simulation, a FPCB pancake sensor was manufactured and the optimal frequency was selected by measuring minute changes in the Cr-coating thickness using the developed sensor.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 학술대회 논문집 정보 및 제어부문
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• pp.711-713
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• 2004

In the past time, the protection relay did only a protection function. Currently, its upgraded device i.e. IED(Intelligent Electric Device) has been designed to protect, control, and monitor the whole power system automatically. Also the device is desired to successfully measure important elements of the power system. This paper considers design method of a digital protection IED with a function of measuring various elements and a communication function. The protection IED is composed of the specific function modules that are signal process module, communication module, input/output module and main control module. A signal process module use a DSP processor for analysis of input signal. Main control module use a embedded processor, Xscale, that has an ARM Core. The communication protocol uses IEC61850 protocol that becomes standard in the future. The protection IED is able to process mass information with high-performance processor. As each function module is designed individually, the reliability of the device can be enhanced.

• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 2001년도 The Pacific Aisan Confrence On Intelligent Systems 2001
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• pp.364-369
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• 2001

As the population of persons over the age of sixty-five is rapidly growing, the population of solitary senior person living at own home is growing in Japan. This situation has caused the social issue of how supports their healthy life. There have been some projects related to improve their quality of life and support their healthy life. Unfortunately mostly they focus the method of measuring vital signal and observing behavior. Nobody reports how utilize the measured data. Aim of our project is how find emergency of the aged people at home. As emergency is big different from regular life behavior, we have to recognize it. We propose concept of the human behavior model and show the some types human behavior knowledge constructed by observed human behavior model and show the some types human behavior knowledge constructed by observed human behavior. This idea is based on human having habitual life. And we discuss the possibility of finding emergency using knowledge and observed data.