• Title/Summary/Keyword: Integrity evaluation

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Potential Probiotic Characteristics and Safety Assessment of Lactobacillus rhamnosus SKG34 Isolated from Sumbawa Mare's Milk

  • Sujaya, I Nengah;Suwardana, Gede Ngurah Rsi;Gotoh, Kazuyoshi;Sumardika, I Wayan;Nocianitri, Komang Ayu;Sriwidyani, Ni Putu;Putra, I Wayan Gede Artawan Eka;Sakaguchi, Masakiyo;Fatmawati, Ni Nengah Dwi
    • Microbiology and Biotechnology Letters
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    • v.50 no.1
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    • pp.51-62
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    • 2022
  • Lactobacillus rhamnosus SKG34 (LrSKG34), a potential probiotic strain, was successfully isolated from Sumbawa Mare's milk. Our previous studies showed that the strain is resistant to gastrointestinal conditions, possesses antioxidant activity, and lowers blood cholesterol levels. Further clarification of the potential probiotic characteristics and safety assessment are necessary. This study aimed to evaluate the adhesion of LrSKG34 to Caco-2 cell monolayers and its effect on mucosal integrity in vitro. We also examined the LrSKG34 safety profile based on antimicrobial susceptibility testing, haemolytic activity determination, Caco-2 cell monolayer translocation evaluation, and in vivo investigation of the effect of LrSKG34 on the physiology, biochemical markers, and histopathological appearance of major organs in an animal model. LrSKG34 attached to Caco-2 cell monolayers and maintained mucosal integrity in vitro. The typical resistance of lactobacilli to ciprofloxacin, gentamicin, vancomycin, trimethoprim-sulfamethoxazole, and metronidazole was confirmed for LrSKG34. No haemolytic activity was observed on blood agar plates, and no LrSKG34 translocation was observed in Caco-2 cell monolayers. Administration of LrSKG34 to Sprague-Dawley rats did not adversely affect body weight. No abnormalities in hematological parameters, serum biochemistry levels, or histopathological structures of major organs were observed in LrSKG34-treated rats. Collectively, the results implicate LrSKG34 as a promising and potentially safe probiotic candidate for further development.

Smart monitoring system using electromagnetic waves to evaluate the integrity of reinforced concrete structural elements

  • Jong-Sub Lee;Dongsoo Lee;Youngdae Kim;Goangseup Zi;Jung-Doung Yu
    • Computers and Concrete
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    • v.31 no.4
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    • pp.293-306
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    • 2023
  • This study proposes and demonstrates a smart monitoring system that uses transmission lines embedded in a reinforced concrete structure to detect the presence of defects through changes in the electromagnetic waves generated and measured by a time-domain reflectometer. Laboratory experiments were first conducted to identify the presence of voids in steel-concrete composite columns. The results indicated that voids in the concrete caused a positive signal reflection, and the amplitude of this signal decreased as the water content of the soil in the void increased. Multiple voids resulted in a decrease in the amplitude of the signal reflected at each void, effectively identifying their presence despite amplitude reduction. Furthermore, the electromagnetic wave velocity increased when voids were present, decreased as the water content of the soil in the voids increased, and increased with the water-cement ratio and curing time. Field experiments were then conducted using bored piles with on-center (sound) and off-center (defective) steel-reinforcement cage alignments. The results indicated that the signal amplitude in the defective pile section, where the off-center cage was poorly covered with concrete, was greater than that in the pile sections where the cage was completely covered with concrete. The crosshole sonic logging results for the same defective bored pile failed to identify an off-center cage alignment defect. Therefore, this study demonstrates that electromagnetic waves can be a useful tool for monitoring the health and integrity of reinforced concrete structures.

Convergence of Related Standard of CC and ISO for Security Evaluation of VPN (VPN의 보안성 평가를 위한 CC와 ISO 관련 표준의 융합)

  • Lee, Ha-Young;Yang, Hyo-Sik
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.341-348
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    • 2016
  • Because VPN(Virtual Private Network) uses internet network, the security technique should support it and evaluation technique based on standard should support it. Therefore the method should be organized that can evaluate the security of VPN based on the related standard. In this study, we intended to construct the security evaluation model through combining CC(Common Criteria) which is a evaluation standard and a part of security(Confidentiality, Integrity, Non-repudiation, Accountability, Authenticity) evaluation of ISO which is the standard of software quality evaluation. For this, we analyzed the quality requirements about intra-technology and security of VPN and constructed the evaluation model related to the quality characteristics of two international standard. Through this, we are able to construct a convergence model for security evaluation of VPN. Through accumulating the evaluation practices for VPN in the future, the suitability and validity of the evaluation model must be improved.

The Verification of TEXAS-V code for TROI Experimental Results and the Evaluation of the Ex-vessel Steam Explosion Load (TROI 실험결과를 활용한 TEXAS-V 코드 검증 및 원자로 노외증기폭발 하중평가)

  • Park, Ik-Kyu;Kim, Jong-Hwan;Min, Beong-Tae;Hong, Seong-Ho;Kim, Hee-Dong;Hong, Seong-Wan
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.3485-3490
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    • 2007
  • The TEXAS-V code tuned for TROI-13 was used for analyzing the parametric findings in TROI experiments. The calculations on the melt composition are relatively similar to the TROI experimental results. The water depth effect in TEXAS-V code seems to be consistent with TROI experiments in some degree. The water area effect of TEXAS-V calculations seems not to be harmonious to that in TROI experiments. This seems to indicate that TEXAS-V as 1-dimensional code or as the numerical steam explosion has a limitation on estimating area effect. Thus, TEXAS-V tuned for TROI-13 seems to have an ability to estimate the parametric effect of TROI experiments. The evaluated TEXAS-V was used for estimating the ex-vessel steam explosion load. The calculated explosion pressure and load were about 40 MPa and 75 kPa.sec, which are not much threatening level for containment integrity, but are arguable value for the integrity.

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Analysis of Municipal Ordinances on Disaster Management: Focused on Busan Metropolitan City and its 16 subregions (지방자치단체의 재난관리체계 개선을 위한 재난관련 조례 분석연구 -부산광역시 및 부산 16개 구·군을 중심으로)

  • Kweon, Sinjung;Yoo, Youngmi;Cho, Sunyoung Michelle
    • Journal of the Society of Disaster Information
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    • v.14 no.1
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    • pp.1-8
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    • 2018
  • Since the problems associated with disaster management have been at the core social issues in Korea, this study analyzes the relevant ordinances of the metropolitan city of Busan and its 16 autonomous subregions, called gu in Korean language, based on the evaluation model of disaster management organizational system, which consists of interrelatedness, professionalism, integrity and responsiveness. As a result, the ordinances related to responsiveness are the most frequently identified in the ordinances, followed by interrelatedness, professionalism and integrity. A range of suggestions are discussed, including: establishing cooperative network between officials and the community; and restructuring of the work system for unity.

Evaluation of Occupant Protection of Van and Light Truck Vehicle (승합 및 경트럭의 탑승자 보호성능 평가)

  • Kim, Guan-Hee;Park, In-Song
    • Transactions of the Korean Society of Automotive Engineers
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    • v.20 no.3
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    • pp.13-19
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    • 2012
  • The fatalities rate for passenger vehicles, vans, and commercial vehicles is 1.23, 1.90 and 2.46 deaths per 10,000 registered vehicles, respectively. This shows that vans and commercial vehicles are vulnerable compare to passenger vehicles. To evaluate the crashworthiness of van and Light Truck Vehicle(LTV), we carried out frontal offset crash test at 64km/h, 40% overlap as per IIHS(Insurance Institute for Highway Safety). The test result show that LTV is very poor to protect occupant at frontal crash cause there is no safety system such as airbag and pretensioner and front end length(distance from front bumper to steering wheel) is short. One of the van rated as the lowest rating even it is equipped with airbag, cause its safety cage was collapsed during the test. This result shows that the structural integrity is very important in terms of occupant protection.

A collapse Stress Analysis of a Heat Exchanger Subjected to External Pressure in a Nuclear Power Plant

  • Kwon, Jae-Do;Lee, Choon-Yeol;Woo, Seung-Wan
    • Journal of Mechanical Science and Technology
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    • v.14 no.11
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    • pp.1216-1224
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    • 2000
  • The collapse pressure of tubes is determined experimentally by Tschoepe and Maison for various materials with different geometries. The results are compared with those obtained by ASME Codes UG-31 and UG-28. A collage pressure is the pressure required for the incipient yielding stress of the tubes with and without ovality. This collapse pressure is compared with the experimental results by Tschoepe and Maison. The present investigation is towards finding the collapse pressure required to bring the entire wall of tubes into a state of plastic flow for the pipes, with ovality and without ovality. This collapse pressure is compared with the collapse pressure obtained through experiments in the present investigation. The experimental results are compared with the pressure obtained by FEM(finite element methods). The FEM results are then compared with results obtained through an approximate plastic analysis of the strain hardening material, SA312-TP304 stainless steel. The structural integrity evaluation is performed for the heat exchanger used in an actual nuclear power plant by using various methods described in this paper. The results obtained by the various analyses and the FEM are discussed. consequently, the paper is oriented towards an actual design purpose of d heat exchanger in an industrial environment, rather than for the purpose of an academic research project investigation.

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Evaluation of Occupant Protection of Passenger Vehicles at IIHS Side Impact (소형 승용차량의 측면충돌 시 탑승자 보호성능 평가)

  • Kim, Guanhee;Lim, Jonghun;Lim, Jangho;Park, Insong;Cho, Chongdu
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.1
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    • pp.46-51
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    • 2014
  • 2,097 deaths out of 5,229 by traffic accident occurred by vehicle to vehicle crash and 855 deaths out of 2,097 occurred at side crash in 2011. Korean government adopted New Car Assessment Program to reduce the wounded and deaths at traffic accident in 1999 and side impact test has been added in 2003. 43 out of 53 vehicles tested in NCAP side impact rated 4 and 5 stars means the highest occupant protection. In this study three small class vehicles have been tested according to Insurance Institute for Highway Safety's side crashworthiness test protocol. IIHS test protocol uses 1,500kg moving barrier rather than NCAP's 950kg and the occupant protection rated Good, Acceptable, Marginal and Poor based on injury measure, structural integrity and head protection.

A Study on Acoustic Emission Characteristics of CFRP in aircraft operations (운항 중 실구조물(항공기 축소모델)에서의 탄소섬유강화플라스틱(CFRP)의 음향방출신호 특성에 관한 연구)

  • Lee, Kyung-Won;An, Ju-Seon;Hwang, Woong-Gi;Lee, Jong-Oh;Lee, Sang-Yul;Lee, Bo-Young
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.18 no.4
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    • pp.59-66
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    • 2010
  • Aerospace structures need high stability and long life because many personal injuries can result from an accident and securing structural integrity for various external environments is more important than any other thing. So first of all we must prove the destruction properties for operating environment, have prediction technology about damage evolution and life, and develop an economical non-destructive technology capable of detecting structure damage. Acoustic emission (AE) have no need of artificial environment like ultrasonic inspection or radio fluoroscopy to emit a certain energy, is a testing technique using seismic signal resulting from interior changes of solids, and enables to observe if any fault is appeared and it grows seriously or not while running. In this study we suggest the method of structural integrity evaluation for aerospace structures through the acoustic emission technique, for which a model plane was manufactured and an actual operation test was conducted.

Improvement of aseismic performance of a PGSFR PHTS pump

  • Lee, Seong Hyeon;Lee, Jae Han;Kim, Sung Kyun;Kim, Jong Bum;Kim, Tae Wan
    • Nuclear Engineering and Technology
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    • v.52 no.8
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    • pp.1847-1861
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    • 2020
  • A design study was performed to improve the limit aseismic performance (LSP) of a primary heat transport system (PHTS) pump. This pump is part of the primary equipment of a prototype generation IV sodium-cooled fast reactor (PGSFR). The LSP is the maximum allowable seismic load that still ensures structural integrity. To calculate the LSP of the PHTS pump, a structural analysis model of the pump was developed and its dynamic characteristics were obtained by modal analysis. The floor response spectrum (FRS) initiated from a safety shutdown earthquake (SSE), 0.3 g, was applied to the support points of the PHTS pump, and then the seismic induced stresses were calculated. The structural integrity was evaluated according to the ASME code, and the LSP of the PHTS pump was calculated from the evaluation results. Based on the results of the modal analysis and LSP of the PHTS pump, design parameters affecting the LSP were selected. Then, ways to improve the LSP were proposed from sensitivity analysis of the selected design variables.