• Proceedings of the Zoological Society Korea Conference
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• 2003.08a
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• pp.197.1-197
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• 2003

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
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• 2003.08a
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• pp.197.2-197
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• 2003

No Abstract, See Full Text

• Journal of The Korean Society of Integrative Medicine
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• v.3 no.4
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• pp.79-90
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• 2015

Purpose : The purpose of this study was to investigate related factors contributing to subjective health state in elderly people with focus on comparison of gender differences. Method : From the database of the Korean National Health and Nutrition Examination Survey(KNHNES) the year 2012 and 2013, the researchers selected 2,924 old adults aged over 65. Data were analyzed with SPSS 18.0 program. Result : Results indicated that education, occupation, restriction of activity, stress, drinking status were significant variables of subjective health state both men and women. But, age, DM, MI, arthritis, smoking status were significant variables of subjective health state of men. And insurance, suicide, HTN, walking exercise were significant variables of subjective health state of women. Conclusion : The development of health and quality of life for elderly people considers different approaches to the genders.

• Journal of TMJ Balancing Medicine
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• v.11 no.1
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• pp.37-40
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• 2021

Objectives: The purpose of this study is to report the effect of Korean medical treatment using Yin-yang Balancing Therapy of TMJ (YBT) on correcting posture. Methods: During the admission period, the patient was treated by Korean medical treatment (YBT, acupuncture, herb medicine, etc) every each day. The standard intraoral balancing appliance was used in patient while sleeping and exercising. Results: After treatment for 35th, the angle changed from 23 degrees to 0 degree. The posture of the neck and shoulder became straight. The distorted facial midline was aligned straight. Conclusions: These results showed that YBT have an effect on correcting posture.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.4
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• pp.460-463
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• 2014

Chemotherapy-induced peripheral neuropathy (CIPN) which is one of the common chemotherapy related toxicity poses a significant clinical challenge. Here we conducted a prospective pilot study to evaluate the efficacy of acupuncture on CIPN. Patients with CIPN were administered acupuncture procedure with continuation of previous conventional medication. Acupuncture procedures were conducted three times per week for 3 weeks. We assessed patients with Common Terminology Criteria for Adverse Events (CTCAE) v4.0, Visual Analog Scale (VAS), Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity (FACT/GOG-Ntx) at the time of baseline and every week after the acupuncture procedures. Total 5 patients were included and treated with acupuncture. CTCAE grades were the same of 2 in all patients. VAS mean value changed from 5.2 to 3.2, and FACT/GOG-Ntx total score that suggests the higher relates to better quality of life changed from 93.3 to 110 as mean value at the end of the 3rd week, though this index difference did not show any statistically significant difference. This pilot study suggests that acupuncture procedure may have a role for CIPN treatment. Launching a more larger and properly controlled study will be required to ascertain the efficacy of acupuncture.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.79-92
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• 2020

Purpose : The purpose of this study was to evaluate the prescription pattern of NSAIDs and GPAs in the arthritis patients over 65 years old to prevent the GI adverse events. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used agents to treat arthritis, can cause gastrointestinal (GI) adverse effects. Recent guidelines recommend that moderate risk patients who have one or two risk factors, should be prescribed either combination of non-selective NSAID (nsNSAIDs) and gastroprotective agent (GPAs) or selective NSAID alone. Methods : Study population was National Patient Sample of 2011. Number of drugs used were 138 for NSAIDs and 21 for GPAs. Chi-square test was used to compare prescribing patterns. Results : The appropriate prescription rate follows the guideline was 11.2%: co-prescription with nsNSAID and proton pump inhibitor (PPI) or misoprostol was 1.6% and selective NSAID alone was 9.6%. Inappropriate prescription rates were as follows: co-prescription with nsNSAID and Histamine-2 receptor antagonist (H2RA) or antiacid was 53.8% and nsNSAID alone was 35.0%. The appropriate prescription rate among the types of medical institute was 54.4% in tertiary hospital, 31.2% in secondary hospital, and 6.0% in primary hospital. The appropriate prescription rate among the regions was 19.4%, highest in Seoul and 4.2%, lowest in Jeju. The appropriate prescription rate among the medical departments was as follow: 12.2% in orthopaedic surgery, 11.0% in internal medicine, and 7.7% in other departments. Conclusion : This finding suggests the needs to revise the national medical insurance imbursement policy, provide continuing medical education about the guideline of medical doctors.

• Journal of Ginseng Research
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• v.46 no.4
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• pp.592-600
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• 2022

Background: Di-(2-ethylhexyl) phthalate (DEHP) is the most common endocrine disrupting chemical used as a plasticizer. DEHP is associated with the development of endometrium-related diseases through the induction of inflammation. The major therapeutic approaches against endometrial cancer and endometriosis involve the suppression of inflammatory response. Korean Red Ginseng (KRG) is a natural product with anti-inflammatory and anti-carcinogenic properties. Thus, the purpose of this study is to investigate the effects of KRG on DEHP-induced inflammatory response in endometrial cancer Ishikawa cells and a mouse model of endometriosis. Methods: RNA-sequencing was performed and analyzed on DEHP-treated Ishikawa cells in the presence and absence of KRG. The effects of KRG on DEHP-induced cyclooxygenase-2 (COX-2) mRNA levels in Ishikawa cells were determined by RT-qPCR. Furthermore, the effects of KRG on the extracellular signal-regulated kinases (ERKs) pathway, COX-2, and nuclear factor-kappa B (NF-kB) p65 after DEHP treatment of Ishikawa cells were evaluated by western blotting. In the mouse model, the severity of endometriosis induced by DEHP and changes in immunohistochemistry were used to assess the protective effect of KRG. Results: According to the RNA-sequencing data, DEHP-induced inflammatory response-related gene expression was downregulated by KRG. Moreover, KRG significantly inhibited DEHP-induced ERK1/2/NF-κB/COX-2 levels in Ishikawa cells. In the mouse model, KRG administration significantly inhibited ectopic endometriosis growth after DEHP-induced endometriosis. Conclusions: Overall, these results suggest that KRG may be a promising lead for the treatment of endometrial cancer and endometriosis via suppression of the inflammatory response.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.15 no.1
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• pp.1-33
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• 2020

연구 목적 : 본 연구는 근골격계 질환에 대한 수기치료가 갖는 경제적 효과를 체계적으로 평가해 보기 위해 시행되었다. 연구 방법 : 2017년 2월 2일까지 국내외 관련 문헌을 체계적으로 검색 하였으며, 연관된 체계적 고찰 논문의 참고문헌을 조사하였다. 두 명의 연구자가 독립적으로 문헌을 선택하고, 비뚤림 위험 평가 및 경제성 평가 질 평가, 자료 추출을 시행하였다. 연구 결과 : 총 3,327개의 논문을 검토하여 최종적으로 18개의 무작위 대조 연구가 포함되었다. 경제성 평가는 수기요법과 다른 치료방법간의 유효성 비교를 통해 시행되었다. 요부 통증, 견관절 통증 및 외측 상과염 치료에 있어 침치료, 견인치료, 주사치료, 일반의 치료, 척추 안정화 기법 및 통증관리 치료보다 비용 효과적인 것으로 나타났다. 또한 또한, 수기치료는 경항통, 흉통, 고관절염 혹은 슬관절염, 경추신경병증 및 수부손상 치료에 있어 일반적 치료, 물리치료, 자가 치료 프로그램, 견인 치료에 비하여 효과적인 치료인 것으로 확인되었다. 결론 : 18개의 논문 중 10개의 논문에서 근골격계 질환 치료에 있어 수기치료가 경제적으로 효과가 있는 것으로 나타났다. 이러한 결과는 다른 치료방법에 비해 수기요법이 근골격계 질환에 있어서 경제적 가치가 있음을 시사하는 내용이다. 하지만, 근골격계 질환 수기치료의 경제성 평가에 대한 선행 연구는 전반적으로 부족한 실정으로, 보다 정확한 결과를 제시하고 정책결정을 위한 효과적인 제안을 위해서는 체계적인 추가 연구가 필요하다 사료되는 바이다.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.4
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• pp.89-104
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• 2019

Purpose : The purpose of this study was to investigate the development of korean vowels by acoustically analyzing whether children produce Korean vowels differently according to their age and gender between ages 4 and 6. Methods : A total of 104 children aged 4~6 years (56 males and 48 females) participated in this study. The participants were classified as either 4, 5, or 6 years old. Vowel speech data was obtained by asking the subjects to pronounce meaningful words in which the vowel in question was located in the first syllable. Speech analysis was performed using the Multi-speech 3700 program. Results : Age, gender, and vowel being pronounced all had significant effects on intensity. There was significant decrease with increasing age, and the intensity was significantly higher in male children than female children. Neither age, gender, nor the vowel being produced affected the fundamental frequency. The fundamental frequency produced did not differ by age or gender. The first and second formants had considerable effect on age and vowels, significantly decreased with age, and did not have a gender difference. Conclusion : The results of this study showed that children aged 4~6 have similar anatomical structures, but that maturity of speech motor skills required to pronounce vowels was correlated with age. The results of this study can be used to evaluate children's speech and develop speech therapy programs.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.59-66
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• 2020

Purpose : This study aimed to present normative data for older Korean adults completing the Yonsei dual task cognitive screening test (Y-DuCog) and identify changes in cognitive function on the Montreal Cognitive Assessment - Korean (MoCA-K) with age. Methods : From May 2019 to August 2019, 195 healthy adults aged ≥60 years participated in this study. All participants completed the Y-DuCog to assess their dual-task performance and the MoCA-K to assess their cognitive function. Participants were divided into three groups based on their age: 60~69 years, 70~79 years, and ≥80 years. Results : The results of the Y-DuCog showed that dual-task performance time, effect, and correct response rate decreased significantly with age (p<.001). Scores from the three groups showed differences on all items (p<.001). Cognitive function on the MoCA-K also decreased significantly with age (mean score ± standard deviation [SD]; 27.33 ± 2.61 in subjects aged 60~69 years; 24.82 ± 3.20 in subjects aged 70~79 years; and 22.10 ± 4.91 in subjects aged ≥80 years; p<.001). Conclusions : Occupational therapists should be aware of the decline in cognitive function and dual-task performance time, effect, and correct response rate in older adults and consider interventions to treat this decline. Further studies are needed with larger groups of participants to examine factors, such as sex and education, that may impact dual-task performance and cognitive function.