• Journal of Ginseng Research
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• v.42 no.1
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• pp.16-20
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• 2018

Background: The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. ginseng have inhibitory effects on inflammation-related factors in HepG2 cells. Methods: Phytosterols (e.g., stigmasterol and ${\beta}$-sitosterol) in the roots of P. ginseng grown under various conditions were analyzed using high-performance liquid chromatography. The P. ginseng roots analyzed in this study were collected from three cultivation areas in Korea (i.e., Geumsan, Yeongju, and Jinan) and differed by cultivation year (i.e., 4 years, 5 years, and 6 years) and production process (i.e., straight ginseng, red ginseng, and white ginseng). Results: The concentrations of stigmasterol and ${\beta}$-sitosterol in P. ginseng roots were 2.22-23.04 mg/g and 7.35-59.09 mg/g, respectively. The highest concentrations of stigmasterol and ${\beta}$-sitosterol were in the roots of 6-year-old P. ginseng cultivated in Jinan (82.14 mg/g and 53.23 mg/g, respectively). Conclusion: Six-year-old white ginseng and white ginseng cultivated in Jinan containing stigmasterol and b-sitosterol are potentially a new source of income in agriculture.

• Proceedings of the Zoological Society Korea Conference
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• 1998.10b
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• pp.215.1-215
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• 1998

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
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• 2000.10a
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• pp.181.1-181
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• 2000

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
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• 1997.10b
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• pp.184.1-184
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• 1997

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
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• 2001.10a
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• pp.189.1-189
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• 2001

No Abstract, See Full Text

• Journal of Ginseng Research
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• v.47 no.1
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• pp.123-132
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• 2023

Background: Pseudotyped virus systems that incorporate viral proteins have been widely employed for the rapid determination of the effectiveness and neutralizing activity of drug and vaccine candidates in biosafety level 2 facilities. We report an efficient method for producing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pseudovirus with dual luciferase and fluorescent protein reporters. Moreover, using the established method, we also aimed to investigate whether Korean Red Ginseng (KRG), a valuable Korean herbal medicine, can attenuate infectivity of the pseudotyped virus. Methods: A pseudovirus of SARS-CoV-2 (SARS-2pv) was constructed and efficiently produced using lentivirus vector systems available in the public domain by the introduction of critical mutations in the cytoplasmic tail of the spike protein. KRG extract was dose-dependently treated to Calu-3 cells during SARS2-pv treatment to evaluate the protective activity against SARS-CoV-2. Results: The use of Calu-3 cells or the expression of angiotensin-converting enzyme 2 (ACE2) in HEK293T cells enabled SARS-2pv infection of host cells. Coexpression of transmembrane protease serine subtype 2 (TMPRSS2), which is the activator of spike protein, with ACE2 dramatically elevated luciferase activity, confirming the importance of the TMPRSS2-mediated pathway during SARS-CoV-2 entry. Our pseudovirus assay also revealed that KRG elicited resistance to SARS-CoV-2 infection in lung cells, suggesting its beneficial health effect. Conclusion: The method demonstrated the production of SARS-2pv for the analysis of vaccine or drug candidates. When KRG was assessed by the method, it protected host cells from coronavirus infection. Further studies will be followed for demonstrating this potential benefit.

• Journal of The Korean Society of Integrative Medicine
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• v.1 no.3
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• pp.37-49
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• 2013

Purpose : The purpose of this study was to evaluate the influence of Respiratory Capacity by Vojta's treatment in children with spastic cerebral palsy. Method : The subjects of this study, children diagnosed with spastic cerebral palsy, 12 patients were picked up, who were agreed with this research and were having hospital care for 4weeks at MH and PR medical centers. Result : In comparison of Respiratory muscle activity and Phonation capacity were significant in the group(p<.01) and MPT and Rectus abd(Rt) were significantly correlated in the pre test and SMR and Ex/oblique (Lt) were significantly correlated in the post test. Conclusion : Therefore, the Vojta's treatment is useful to improve the Respiratory muscle activity and Phonation capacity in children with spastic cerebral palsy.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.4
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• pp.213-222
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• 2019

Purpose : The purpose of this study was to compare stress and psychological status between a stroke and a fracture patient's caregivers. Methods : Data was collected from September to December 2018 and participants of this study were 60 stroke and 61 fracture patient's caregivers. Stress was evaluated with the Global Assessment of Recent Stress scale-Korean Version and psychological status was measured with the Symptom check List-90-Revision. Results : The stroke patient's caregivers scored significantly higher than the fracture patient's caregivers in stress relevant to interpersonal, change in relationship, sickness or injury, financial, change/no change in routine (p<.05). The stroke patient's caregivers scored significantly higher in somatization, interpersonal sensitivity, depression, anxiety, paranoid ideation, and psychoticism than the fracture patient's caregivers (p<.05). Conclusion : It was found that the severity of mental health in the stroke patient's caregivers is necessary to develop a customized mental health improvement program for stroke patient's caregivers.

• Journal of The Korean Society of Integrative Medicine
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• v.3 no.4
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• pp.23-27
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• 2015

Objectives : This Study was to understand the relationship between smoking and drinking behaviors among some Korean university and college students. Methods : This study is based on data from National Survey of Health and Nutrition 2013 carried by Ministry of Health and Welfare. The respondents consisted of 319 students. The data were analyzed by using SPSS 18.0 program. Results : The analysis of the correlation between smoking and drinking behaviors. Conclusions : To explore the smoking and drinking problem among university and college students, the first step should be a national representative survey with scientific methods. And health promotion program should be targeted at university and college students considering smoking and drinking behaviors. Also, the health policy for students, through various ways, such as health counselling service, health education should be employed.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.2
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• pp.31-38
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• 2019

Purpose : This study aimed to investigate the correlation between social participation and interpersonal relationships after stroke. Methods : Scores for the Korean version of the Reintegration to Normal Living Index (K-RNLI) and the Relationship Change Scale (RCS) were determined using a face-to-face test for 98 patients who had a stroke between September 3, 2018, and January 10, 2019. SPSS 22.0 was used for the analysis, and the correlation coefficient between social participation and interpersonal relationships was determined. Results : According to the patients' general characteristics, social participation was related to sex, type of lesion, and affected side, and interpersonal relationships showed a significant difference with respect to the affected side (p<.05). The analysis of social participation and interpersonal relationships of the subjects revealed a high correlation with total score (r=.364; p<.01), and all the items showed correlations except sensitivity (p<.05). Conclusion : Social participation and interpersonal relationships are important factors for reintegrating stroke patients into the community. The results of this study suggest a clinical basis for rehabilitation interventions in stroke patients.