• Title/Summary/Keyword: Integrative Evaluation

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Analysis of the Correlation Between Sarcopenia and Locomotive Syndrome in the Elderly in Korea (국내 노인의 근감소증과 운동기능저하증후군에 대한 분석 연구)

  • Kim, Myung-Chul;Cheon, Ji-Yeon;Kim, Hae-In;Chung, Dong-Kun;Bae, Won-Sik
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.2
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    • pp.1-11
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    • 2022

  • Purpose : This study was conducted to assess the status of sarcopenia and locomotive syndrome in the Korean elderly population over 65 years of age by applying the recently updated screening tool for diagnostic evaluation of sarcopenia and locomotive syndrome. Methods : Sarcopenia and locomotive syndrome (LS) were diagnosed and evaluated in 210 Korean elderly people over 65 years of age. There were 36 patients in the "sarcopenia group", 164 in the "locomotive syndrome group", and 10 in the "normal group". The collected data were analyzed using the chi-square and Kruskal-Wallis tests. Results : The diagnostic evaluation of sarcopenia and LS showed the presence of sarcopenia in 9.05 % of males and 8.10% females among the Korean elderly population over 65 years of age. Prevalence of stage 1 locomotive syndrome (LS 1) was 95.24 %; stage 2, (LS 2) 36.19 %; and stage 3 (LS 3), 16.19 % among the study population. Both the sarcopenia diagnostic indicator and the LS evaluation indicators showed significant differences between the three groups. All the subjects in the sarcopenia group had LS; further, on comparison of the detailed composition ratio of each patient with LS, the prevalence of LS in the sarcopenia group was found to be: LS 1 41.67 %, LS 2 41.67 %, and LS 3 16.67 %, whereas in the LS group, it was found to be: LS 1 66.46 %, LS 2 16.46 %, and LS 3 17.07 %. The difference between the two groups was statistically significant. Conclusion : It was confirmed that sarcopenia is correlated with LS incidence. This suggests that the evaluation of motor LS can be used as a tool for the early diagnosis and prevention of sarcopenia in cases of functional decline due to aging in the elderly population.

  • https://doi.org/10.15268/ksim.2022.10.2.001 인용 PDF KSCI HTML

Cumulative Probability of Prostate Cancer Detection Using the International Prostate Symptom Score in a Prostate-specific Antigen-based Population Screening Program in Japan

  • Kitagawa, Yasuhide;Urata, Satoko;Narimoto, Kazutaka;Nakagawa, Tomomi;Izumi, Kouji;Kadono, Yoshifumi;Konaka, Hiroyuki;Mizokami, Atsushi;Namiki, Mikio
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7079-7083
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    • 2014

  • The International Prostate Symptom Score (IPSS) is often used as an interview sheet for assessing lower urinary tract symptoms (LUTS) at the time of prostate-specific antigen (PSA) testing during population-based screening for prostate cancer. However, the relationship between prostate cancer detection and LUTS status remains controversial. To elucidate this relationship, the cumulative probability of prostate cancer detection using IPSS in biopsy samples from patients categorized by serum PSA levels was investigated. The clinical characteristics of prostate cancer detected using IPSS during screening were also investigated. A total of 1,739 men aged 54-75 years with elevated serum PSA levels who completed the IPSS questionnaire during the initial population screening in Kanazawa City, Japan and underwent systematic transrectal ultrasonography-guided prostate biopsy between 2000 and 2013 were enrolled in the present study. Of the 1,739 men, 544 (31.3%) were diagnosed with prostate cancer during the observation period. The probability of cancer detection at 3 years in the entire study population was 27.4% and 32.7% for men with $IPSS{\leq}7$ and those with $IPSS{\geq}8$, respectively; there was no statistically significant difference between groups. In men with serum PSA levels of 6.1 to 12.0ng/mL at initial screening, the probability of cancer detection was significantly higher in men with $IPSS{\leq}7$ than in those with $IPSS{\geq}8$. There were no significant differences in clinical characteristics between groups of patients stratified by IPSS. These findings indicate that the use of IPSS for LUTS status evaluation may be useful for prostate cancer detection in the limited range of serum PSA levels.

  • https://doi.org/10.7314/APJCP.2014.15.17.7079 인용 PDF KSCI

Development of Rainfed-adapted, Fertilizer-efficient Temperate Rice Varieties by Pup1 Introgression

  • Ian Paul Navea;Jae-Hyuk Han;Na-Hyun Shin;Yeong-Ju Lee;Joong Hyoun Chin
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.272-272
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    • 2022

  • Water and phosphorus (P) fertilizer are two of the most critical inputs in rice cultivation. Under climate change scenarios and urbanization, irrigation and fertilizer are becoming limiting factors often leading to significant decrease in yield whenever supplied scarcely. It has been shown that the Pup1 QTL confers tolerance to P starvation and improved early-stage root vigor in indica rice grown in the tropics. However, whether the QTL works in japonica rice genetic background grown in temperate regions remains to be elucidated. Here, we have introgressed the Pup1 QTL into three temperate rice varieties MS11, TR22183, and Dasan using marker-assisted backcrossing and next generation sequencing. The selected lines all harbored the full Pup1 QTL with recurrent parent genome recovery rates ranging from 66.5% to 99.8%. Evaluation of the introgression rice lines grown in South Korea under low inputs of P and water revealed early vegetative growth advantage relative to that of the recurrent parents. Under rainfed condition, Pup1 introgression lines had yield advantage ranging from 7.2 to 19.9% and 24 to 26% in P non-supplied soil and P-supplied soil, respectively compared to that of the recurrent parents suggesting that Pup1 confers enhanced yield under low P and water inputs in temperate rice genetic background grown in temperate climate. In terms of early vegetative growth, temperate Pup1 introgression lines showed a similar trend on the extent to which Pup1 promotes yield advantage in temperate rice in comparison with indica control Pup1 introgression line IR64-Pup1.

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