• 산업융합연구
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• 제2권1호
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• pp.73-89
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• 2004

This study uses theoretical perspectives and models from organizational ecology to examine the dynamics and viability of strategic groups. Integrating the ecological perspective and the contingency theoretical view of strategic management, this study developed propositions demonstrating the impact of environmental density and variation on the effectiveness of strategic groups. Justifications for linking ecological perspectives to strategic management theory are discussed and the importance of the integrative approach to strategic management is highlighted.

• Journal of Preventive Medicine and Public Health
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• 제54권4호
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• pp.259-264
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• 2021

Traditional epidemiological studies have identified a number of risk factors for various diseases using regression-based methods that examine the association between an exposure and an outcome (i.e., one-to-one correspondences). One of the major limitations of this approach is the "black-box" aspect of the analysis, in the sense that this approach cannot fully explain complex relationships such as biological pathways. With high-throughput data in current epidemiology, comprehensive analyses are needed. The network approach can help to integrate multi-omics data, visualize their interactions or relationships, and make inferences in the context of biological mechanisms. This review aims to introduce network analysis for systems epidemiology, its procedures, and how to interpret its findings.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2012년도 춘계학술대회 논문집
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• pp.439-440
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• 2012

New analysis methods complement classical approaches in the vehicle NVH development by reducing and accelerating iteration steps to obtain a target sound. Therefore, tools are required that allow an integrative approach of sound engineering and structural analysis and enable a precise simulation and modification based on measured data. The Response Modification Analysis (RMA) is such a hybrid solution, which provides indications of relevant transfer paths taking into account the sensitivity of response channels to modifications of reference channels.

• Structural Engineering and Mechanics
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• 제52권4호
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• pp.739-753
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• 2014

There have been many packages that can be employed to analyze plane frames. However, because most structural analysis packages suffer from closeness of system, it is very difficult to integrate it with an optimization package. To overcome the difficulty, we proposed a possible alternative, DAMDO, which integrate Design, Analysis, Modeling, Definition, and Optimization phases into an integrative environment. The DAMDO methodology employs neural networks to integrate structural analysis package and optimization package so as not to need directly to integrate these two packages. The key problem of the DAMDO approach is how to generate a set of reasonable random designs in the first phase. According to the characteristics of optimized plane frames, we proposed the ratio variable approach to generate them. The empirical results show that the ratio variable approach can greatly improve the accuracy of the neural networks, and the plane frame optimization problems can be solved by the DAMDO methodology.

• Journal of the Korean Data and Information Science Society
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• 제24권3호
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• pp.515-521
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• 2013

건강 관리에 있어서 서양의학과 한의학의 접근 방법의 차이는 자연과 인간의 이해에 대한 문화적인 차이에서 비롯된다. 서양의학에서는 자연과 인간을 분리하고 인간 또한 여러 하위 시스템으로 나누고, 질병을 외부의 자극에 대한 반응이 적절하지 못하여 초래되는 것으로 보고 질병이 발생되면 시스템 별로 진단하여 치료해 왔다. 반면, 한의학의 경우 자연과 인간을 하나로 보고 인간의 건강을 자연과의 조화로운 상태로 규명하고 질병이 발생하기 전에 건강의 균형을 유지하기 위한 면역 기능을 높이는 예방적 치료를 주로 해왔다. 이러한 인간에 대한 근본적인 접근방법의 차이는 의료 전달체계를 양분화 시키고 상호 의사소통의 어려움을 야기했으나 통합 의료 서비스는 두 가지 의학의 장점을 살리고 최상의 치료 효과를 지향하는 시도라고 할 수 있다. 따라서 본 논문에서는 특정 질환인 황달에 대해 한의학적 분류 (습증, 열증)에 따른 서양의학에서 사용하는 혈액학적 검사수치를 통계적 분석기법을 사용하여 살펴보고 차이가 있는 수치를 살펴봄으로써 통합의료적 환자 진단과 치료에 적용할 수 있는 접근 방법을 살펴보고자 한다.

• East Asian mathematical journal
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• 제34권4호
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• pp.537-548
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• 2018

An integrated approach has been regarded as important in mathematics education. The ultimate ideal of mathematics education is the development of whole person in students. However, mathematics education has not been successful in achieving this ideal. The purpose of this article is to identify an integrated approach to secondary mathematics education in order to achieve the ideal of the whole person. In particular, Ideas for an integrated approach for mathematical activities are sought. This study starts with analysis of recent attempts to integrate knowledge and attitude of mathematics education. Finally, some suggestions for the cultural and institutional conditions in which these integrative ideas can be effectively realized in secondary school.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2012년도 춘계학술대회 논문집
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• pp.132-137
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• 2012

To enhance the CAE accuracy, the definition of material behavior is one of key influence on the result. In case of plastic material with fiber reinforcement, the anisotropic material behavior should be taken into account to increase of CAE accuracy. BASF has developed an innovative CAE tool, ULTRASIM$^R$, which is capable of generating material models of thermoplastic materials for structural simulation. ULTRASIM$^R$, not only the glass fiber orientation effect, but also the weld line effect, tensile-compression anisotropy, strain rate effect are combined in a non-linear material law, which will be evaluated in a unique failure criterion, thus resulting in an highly accurate CAE approach.

• Journal of Ginseng Research
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• 제46권6호
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• pp.750-758
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• 2022

Background: Mild cognitive impairment (MCI) is a transitional condition between normality and dementia. Ginseng is known to have effects on attenuating cognitive deficits in neurogenerative diseases. Ginsenosides are the main bioactive component of ginseng, and their protein targets have not been fully understood. Furthermore, no thorough analysis is reported in ginsenoside-related protein targets in MCI. Methods: The candidate protein targets of ginsenosides in brain tissues were identified by drug affinity responsive target stability (DARTS) coupled with label-free liquid chromatography-mass spectrometry (LC-MS) analysis. Network pharmacology approach was used to collect the therapeutic targets for MCI. Based on the above-mentioned overlapping targets, we built up a proteineprotein interaction (PPI) network in STRING database and conducted gene ontology (GO) enrichment analysis. Finally, we assessed the effects of ginseng total saponins (GTS) and different ginsenosides on mitochondrial function by measuring the activity of the mitochondrial respiratory chain complex and performing molecular docking. Results: We screened 2526 MCI-related protein targets by databases and 349 ginsenoside-related protein targets by DARTS. On the basis of these 81 overlapping genes, enrichment analysis showed the mitochondria played an important role in GTS-mediated MCI pharmacological process. Mitochondrial function analysis showed GTS, protopanaxatriol (PPT), and Rd increased the activities of complex I in a dose-dependent manner. Molecular docking also predicted the docking pockets between PPT or Rd and mitochondrial respiratory chain complex I. Conclusion: This study indicated that ginsenosides might alleviate MCI by targeting respiratory chain complex I and regulating mitochondrial function, supporting ginseng's therapeutic application in cognitive deficits.

• Journal of Power Electronics
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• 제2권4호
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• pp.231-239
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• 2002

This paper describes the restructuring of power electronics and electric drives courses, sponsored by NSF, EPRI, NASA and the local utilities, which has significantly increased student enthusiasm, and the undergraduate enrollment in these courses at the University of Minnesota has tripled since 1997. The developed leaching approaches have been the subject of NSF-sponsored faculty workshops in 1994, 1997, 1998,2002, and 2003. In power electronics, the power-pole based building-block approach unifies analysis and control aspects of all converters. PSpice-based simulations aid in analysis and design, supported by a hardware laboratory. For electric drives, an integrative approach addressing all three aspects of electric drives - machines, power converters and control is being. used. Space vectors, introduced on a physical basis rather than purely mathematical ions, are used fur analysis of ac machines. This leads to a more physical understanding of machine operation and also makes it easier to address control aspects in the advanced course. The lecture materials are supported by a DSP-based laboratory.

• 한국비블리아학회지
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• 제21권1호
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• pp.89-103
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• 2010

정보접근, 획득, 이용자와 정보시스템과의 상호작용과 관련된 내용 중심으로 연구된 이용자 연구는 변화된 정보환경에서 정보획득과 공유행위를 포함한 정보행위 관점에서 연구할 필요가 있다. Wilson의 정보행위 개념을 적용하여 도서관과 인터넷 환경에서 이용자 정보획득과 공유행위의 요구 및 동기, 과정의 내용을 분석하기 위해 질적 연구와 양적 연구의 통합적 접근을 시도하였다. 통합적 분석을 토대로 정보서비스 개선방안을 제시하였다.