• Title/Summary/Keyword: Integrated-optic sensor

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A Disposable Grating-Integrated Multi-channel SPR Sensor Chip for Detection of Biomolecule (회절격자가 집적된 일회용 다중채널 SPR 생체분자 검출 칩)

  • Jin, Young-Hyun;Cho, Young-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.1
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    • pp.147-154
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    • 2009
  • This paper presents a grating~integrated SPR (Surface Plasmon Resonance) sensor chip for simple and inexpensive biomolecule detection. The grating-integrated SPR sensor chip has two sensing channels having a nano grating for SPR coupling. An external mirror is used for multi channel SPR sensing. The present sensor chip replaces bulky and expensive optical components, such as fiber-optic switches or special shaped prisms, resulting in a simple and inexpensive wavelength modulated multi-channel SPR sensing system. We fabricate a SPR sensor chip integrated with 835 nm-pitch gratings by a micromolding technique to reduce the fabrication cost. In the experimental characterization, the refractive index sensitivity of each sensing channel is measured as $321.8{\pm}8.1nm$/RI and $514.3{\pm}8.lnm$/RI, respectively. 0.5uM of the target biomolecule (streptavidin) was detected by a $1.13{\pm}0.16nm$ shift of the SPR dip in the 10%-biotinylated sample channel, while the SPR dip in the reference channel for environmental perturbation monitoring remained at the same position. From the experimental results, multi-channel biomolecule detection capability of the present grating-integrated SPR sensor chip has been verified. On the basis of the preliminary experiments, we successfully measured the binding reaction rate for the $2\;nM{\sim}200\;nM$ monoclonal-antibiotin, thus verifying biomolecule concentration detectability of the present SPR sensor chip. The binding reaction rates measured from the present SPR sensor chip agredd well with those from a commercialized SPR sensor.

Design of Integrated-Optic Biosensor Based on the Evanescent-Field and Two-Horizontal Mode Power Coupling of Si3N4 Rib-Optical Waveguide (Si3N4 립-광도파로의 두-수평모드 파워결합과 소산파 기반 집적광학 바이오센서 설계)

  • Jung, Hongsik
    • Journal of Sensor Science and Technology
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    • v.29 no.3
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    • pp.172-179
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    • 2020
  • We studied an integrated-optic biosensor configuration that operates at a wavelength of 0.63 ㎛ based on the evanescent-wave and two horizontal mode power coupling of Si3N4 rib-optical waveguides formed on a Si/SiO2/Si3N4/SiO2 multilayer thin films. The sensor consists of a single-mode input waveguide, followed by a two-mode section which acts as the sensing region, and a Y-branch output for separating the two output waveguides. The coupling between the two propagating modes in the sensing region produces a periodically repeated optical power exchanges along the propagation. A light power was steered from one output channel to the other due to the change in the cladding layer (bio-material) refractive index, which affected the effective refractive index (phase-shift) of two modes through evanescent-wave. Waveguide analyses based on the rib optical waveguide dimensions were performed using various numerical computational software. Sensitivity values of 12~23 and 65~165 au/RIU, respectively for the width and length of 4 ㎛, and 3841.46 and 26250 ㎛ of the two-mode region corresponding to the refractive index range 1.36~1.43 and 1.398~1.41, respectively, were obtained.

Development a glucose-FIA system with a fiber optic oxygen sensor

  • Sohn, Ok-Jae;Lam, Tuan-Hung;Rhee, Jong-Il
    • 한국생물공학회:학술대회논문집
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    • 2005.10a
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    • pp.730-734
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    • 2005
  • Flow injection analysis (FIA) system was developed to monitor glucose concentrations in biotechnological processes. A fiber optic oxygen sensor was used to determine consumption of oxygen concentration by reaction of immobilized glucose oxidase (GOD). The GOD was immobilized on VA-Epoxy carrier and integrated into FIA system. A calibration curve for glucose was obtained in the range of 0.5 $g/L{\sim}3.0$ g/L.

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A Study on the Fabrication of Integrated Optical Electric-Field Sensor and Performance utilizing Asymmetric $Ti:LiNbO_3$ Mach-Zehnder Interferometer (비대칭 $Ti:LiNbO_3$ Mach-Zehnder 간섭기를 이용한 집적광학 전계센서 제작 및 성능에 관한 연구)

  • Ha, Jeongho;Jung, Hongsik
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.10
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    • pp.128-134
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    • 2012
  • The performance evaluation and fabrication of integrated-optic electric-field sensor utilizing $Ti:LiNbO_3$ asymmetric Mach-Zehnder intensity modulator with a push-pull lumped electrode and a plate-type probe antenna to measure an electric field strength is described. The modulator has a small device size of $46{\times}7{\times}1\;mm$ and operates at a wavelength $1.3{\mu}m$. The devices are simulated based on the BPM software and fabricated utilizing Ti-diffused $LiNbO_3$ channel optical waveguides. The minimum detectable electric field is 1.02 V/m and 6.91 V/m, corresponding to a dynamic range of ~35 dB and ~10 dB at the frequencies of 500 KHz and 5 MHz, respectively.

Fiber optic shape sensor system for a morphing wing trailing edge

  • Ciminello, Monica;Ameduri, Salvatore;Concilio, Antonio;Dimino, Ignazio;Bettini, Paolo
    • Smart Structures and Systems
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    • v.20 no.4
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    • pp.441-450
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    • 2017
  • The objective of this work is to present a conceptual design and the modelling of a distributed sensor system based on fiber optic devices (Fiber Bragg Grating, FBG), aimed at measuring span-wise and chord-wise variations of an adaptive (morphing) trailing edge. The network is made of two different integrated solutions for revealing deformations of the reference morphing structure. Strains are confined to typical values along the span (length) but they are expected to overcome standard ranges along the chord (width), up to almost 10%. In this case, suitable architectures may introduce proper modulations to keep the measured deformation low while preserving the information content. In the current paper, the designed monitoring system combines the use of a span-wise fiber reinforced patch with a chord-wise sliding beam. The two elements make up a closed grid, allowing the reconstruction of the complete deformed shape under the acceptable assumption that the transformation refers to regular geometry variations. Herein, the design logic and some integration issues are reported. Preliminary experimental test results are finally presented.

Optimization of Thermo-Optic Parameters for Temperature-Insensitive LPWG Refractometers

  • Lee, Dong-Seok;Kim, Kyong-Hon;Hwang, Seok-Hyun;Lee, Min-Hee;Lee, El-Hang
    • ETRI Journal
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    • v.28 no.6
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    • pp.739-744
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    • 2006
  • In this paper, we report numerically calculated results of testing a temperature-insensitive refractive sensor based on a planar-type long-period waveguide grating (LPWG). The LPWG consists of properly chosen polymer materials with an optimized thermo-optic coefficient for the core layer in a four-layer waveguide structure. The resonant wavelength shift below the spectral resolution of the conventional optical spectrum analyzer is obtained accurately over a temperature change of ${\pm}7.5^{\circ}C$ even without any temperature control. The refractive index sensitivity of the proposed grating scheme is about 0.004 per resonant wavelength shift of 0.1 nm for an optimized thermo-optic coefficient.

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Common-path Optical Coherence Tomography for Biomedical Imaging and Sensing

  • Kang, Jin-U.;Han, Jae-Ho;Liu, Xuan;Zhang, Kang
    • Journal of the Optical Society of Korea
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    • v.14 no.1
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    • pp.1-13
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    • 2010
  • This paper describes a development of a fiber optic common-path optical coherence tomography (OCT) based imaging and guided system that possess ability to reliably identify optically transparent targets that are on the micron scale; ability to maintain a precise and safe position from the target; ability to provide spectroscopic imaging; ability to imaging biological target in 3-D. The system is based on a high resolution fiber optic Common-Path OCT (CP-OCT) that can be integrated into various mini-probes and tools. The system is capable of obtaining >70K A-scan per second with a resolution better than $3\;{\mu}m$. We have demonstrated that the system is capable of one-dimensional real-time depth tracking, tool motion limiting and motion compensation, oxygen-saturation level imaging, and high resolution 3-D images for various biomedical applications.

A Study on the Design and Performance of Integrated-Optic Biosensor utilizing the Multimode Interferometer based on Si3N4 Rib-Optical Waveguide and Evanescent-Wave (Si3N4 립-광도파로 기반 다중모드 간섭기와 소산파를 이용하는 집적광학 바이오센서 설계 및 성능에 관한 연구)

  • Jung, Hong sik
    • Journal of IKEEE
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    • v.24 no.2
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    • pp.409-418
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    • 2020
  • In this paper, an integrated optical, evanescent-wave biosensor utilizing a multimode interferometer based on a Si3N4 rib-optical waveguide consisting of the Si/SiO2/Si3N4/SiO2 stacked structure was described. The theoretical background of the multimode interferometer was reviewed, and the structure and design process were presented through numerical computational analysis. We analyzed how the dimension (length, width) of the multimode interferometer affected the sensor performance. It has been confirmed through computational analysis that the changes in the refractive index of an analyte greatly affect the mode pattern formation position and output optical power of a multimode interferometer, and proved that this principle could be applied to integrated-optic biosensor.

Sensitivity Analysis for Specifications of Silicon-on-Insulator (SOI) Slot Optical Waveguide-based Single and Add-drop Channel Ring-resonant Biochemical Integrated Optical Sensors (SOI 슬롯 광 도파로 기반 단일 및 삽입-분기 채널 링-공진형 바이오·케미컬 집적광학 센서의 제원에 대한 감도 해석)

  • Jang, Jaesik;Jung, Hongsik
    • Journal of Sensor Science and Technology
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    • v.31 no.2
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    • pp.107-114
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    • 2022
  • The effects of ring radius and coupling spacing on the free spectral range (FSR), full width at half maximum (FWHM), quality factor, and sensitivity of single-channel and add-drop channel slot ring resonators were systematically investigated using FIMMPROP and PICWAVE numerical software. The single-channel ring resonator exhibited better characteristics, namely, a wider FSR and narrower FWHM compared with the add-drop structure; thus, it was evaluated to be more suitable for biochemical sensors. The FSR, FWHM, quality factor, and sensitivity for a single channel ring resonator with a radius of 59.4 ㎛ and coupling gap of 0.5 ㎛ were 2.4 nm, 0.087 nm, 17677, and 550 [nm/RIU], respectively.

Multiplexed Hard-Polymer-Clad Fiber Temperature Sensor Using An Optical Time-Domain Reflectometer

  • Lee, Jung-Ryul;Kim, Hyeng-Cheol
    • International Journal of Aeronautical and Space Sciences
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    • v.17 no.1
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    • pp.37-44
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    • 2016
  • Optical fiber temperature sensing systems have incomparable advantages over traditional electrical-cable-based monitoring systems. However, the fiber optic interrogators and sensors have often been rejected as a temperature monitoring technology in real-world industrial applications because of high cost and over-specification. This study proposes a multiplexed fiber optic temperature monitoring sensor system using an economical Optical Time-Domain Reflectometer (OTDR) and Hard-Polymer-Clad Fiber (HPCF). HPCF is a special optical fiber in which a hard polymer cladding made of fluoroacrylate acts as a protective coating for an inner silica core. An OTDR is an optical loss measurement system that provides optical loss and event distance measurement in real time. A temperature sensor array with the five sensor nodes at 10-m interval was economically and quickly made by locally stripping HPCF clad through photo-thermal and photo-chemical processes using a continuous/pulse hybrid-mode laser. The exposed cores created backscattering signals in the OTDR attenuation trace. It was demonstrated that the backscattering peaks were independently sensitive to temperature variation. Since the 1.5-mm-long exposed core showed a 5-m-wide backscattering peak, the OTDR with a spatial resolution of 40 mm allows for making a sensor node at every 5 m for independent multiplexing. The performance of the sensor node included an operating range of up to $120^{\circ}C$, a resolution of $0.59^{\circ}C$, and a temperature sensitivity of $-0.00967dB/^{\circ}C$. Temperature monitoring errors in the environment tests stood at $0.76^{\circ}C$ and $0.36^{\circ}C$ under the temperature variation of the unstrapped fiber region and the vibration of the sensor node. The small sensitivities to the environment and the economic feasibility of the highly multiplexed HPCF temperature monitoring sensor system will be important advantages for use as system-integrated temperature sensors.