• The Journal of KAIRB
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• v.4 no.2
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• pp.36-41
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• 2022

Purpose: The purpose of this study is to evaluate how university hospital Institutional Review Boards (IRBs) in Korea classify risk when reviewing clinical trial protocols. Methods: IRB experts (IRB chairman, vice chairman, IRB administrator) in the university hospitals obtaining a Human research protection program (HRPP) or IRB accreditation in Korea were asked to fill out the Google Survey from September 1, 2020 to October 10, 2020. Result: Among the 23 responder hospitals, 8 were accredited by the American Association for Human Research Protection Program (AAHRPP) and 8 were accredited by the HRPP of Ministry of Food and Drug Safety (MFDS). Seven were accredited by Forum for Ethical Review Committees in Asia and the Western Pacific or Korea National Institution for Bioethics Policy. Thirteen of 23 hospitals (56.5%) had 4 levels (less than minimal, low, moderate, high risk), 4 hospitals had 3 levels (less than, slightly over, over than minimal risk), 1 hospital had 5 levels (4 levels plus required data safety monitoring board), and 1 hospital had 2 levels (less than, over than minimal risk) risk classification system. Thirteen of 23 hospitals (56.5%) had difficulty classifying the risk levels of research protocols. Fourteen hospitals (60.9%) responded that different standards among hospitals for risk level determination associated with clinical trials will affect the subject protection. Six hospitals (26.1%) responded that it will not. Three hospitals (13.0%) responded that it will affect the beginning of the clinical trial. To resolve differences in standards between hospitals, 14 hospitals (60.9%) responded that either the Korean Association of IRB or MFDS needs to provide a guideline for risk level determination in clinical trials: 5 hospitals (21.7%) responded education for IRB members and researchers is needed; 3 hospitals (13.0%) responded that difference among institutions needs to be acknowledged; and 1 hospital (4.3%) responded that there needs to be communication among IRB, investigator, and sponsor. Conclusion: After conducting a nationwide survey on how IRB in university hospital determines risk during review of clinical trials, it is reasonable to use 4-level risk classification (less than minimal, low, moderate, high risk); the most utilized method among hospitals. Moreover, personal information and conflict of interest associated with clinical trials have to be considered when reviewing clinical trial protocols.

• Korean Journal of Agricultural Science
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• v.32 no.2
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• pp.107-126
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• 2005

The most limited production resource in Korea is land. During the period from 1995 to 2002, annual farm land area of 17,600ha have been converted to urban and industrial land. The self-sufficiency rate of rice, Korean staple food, is expected to be decreased from 97.5% in 2003 to 60-70% in 2020. Under such conditions, this study is aimed at first identifying multi-functional benefits of the reclamation projects such as agricultural production, industrial water supply, urban land supply, transportation effects, sightseeing effects and environmental values with and without the projects. To carry out the objectives, three existing tideland reclamation projects such as Daeho, Kumgang and Yongsangang irrigation project stage II were evaluated and Saemangeum tideland reclamation project which was jointly revaluated by environmental NGO and Govn't appointed specialists in 2000 was reviewed. According to this study results, tide land reclamation projects were showed financially and economically feasible and environmentally sustainable. The joint cost like estuary dam should be allocated based on the multi-functional benefits of the projects. To allocate the joint cost, legal and institutional improvement should adapt the joint cost allocation method as the specific cost-remaining benefit method. Korea has more than 402,000 ha of tidal flat of which 76,396ha have been reclaimed in 2003. To meet food security and to cope with shortage of land, phil-environmental reclamation projects should be continuously implemented and necessary tidal flats for protecting environmental ecosystem should be remained according to the detail survey results of reclaimable resources.

• Korean Journal of Agricultural Science
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• v.29 no.1
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• pp.55-65
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• 2002

The most representative fruit in Yanbian area is Applepear(Ping Guo Li). It has been a important resource of farm income. According to the economic growth and income Increase of individual consumers, food consumption pattern will be changed from grain to high value cash crops such as Applepear and vegetables. The globalization and adapt ion of free market oriented economic policy of China government have led to change the collective farming system to individual farm management system. The institutional transformation have brought about high productivity of farm products and incomes of farmers. Therefore the plantation area of Applepear and requirement of investment cost for establishment of Applepear farms have increased rapidly since the 1980's, the time of perestroika and glasnost in Chinese economy. In prosperity of Chinese agriculture, individual farmer's decision making as free selection of farmland use, selection of high pay-off crops, free sale of the products in free market and credit support for the project might be the most important factors. In case of Applepear farm development, net present value of the project net benefit was estimated at 55.518won per hectare and financial rate of return was 21%. The benefit/cost ratio of the project was 2.11. Considering 10% of discounting rate or the opportunity cost of capital in China the Applepear farm development project showed us economically feasible in the light of the above efficiency indices. The Chinese government has to support Applepear farm development project financially and institutionally considering the high-payoff benefit of the fruit and farmer's in come increase in the future.

• Korean Journal of Biological Psychiatry
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• v.19 no.4
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• pp.153-158
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• 2012

Understanding of a clinical trial is essential in developing clinical guideline and adopting evidence based practice. In designing and executing clinical trials, following ethical requirements should be considered : social value, scientific validity, fair subject selection, informed consent, favorable risk-benefit ratio, institutional review board, and respect for human subjects. According to the stage of drug development, purpose of trials, accumulated scientific data, clinical trials for drug development are classified as phase 1, 2, 3, and 4. Phases of clinical trials can be overlapped and the judgment of entering into the next phase should be considered highly strategically. In reading, evaluating and interpreting clinical trial reports, various skills and challenges exist. Patient sample composition, trial duration, selection of endpoints, responders and non-responders, placebo effect, patient recruitment, and extrapolation to the real world are the examples of those challenges. Treatment success will come from the well balanced approach of evidence based decision making and consideration of specific single case.

• Journal of Korea Technology Innovation Society
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• v.3 no.2
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• pp.78-93
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• 2000

Since computerized numerical controller(CNC) emerged as a result of the fusion of the electronics technology and the mechanical technology, there has been continuous evolution of CNC technology in the mechatronics industry. The industry is recently developing a new control system based on the fusion of personal computer(PC) and CNC. Upgraded PC has now integrated into CNC, making various machines possible to exchange data, software and hardware, and to greatly improve man-machine interface. The fusion of PC and CNC can form a new paradigm in technological innovation of not only control system but also whole machinery industry in near the future. Korea lagged behind the developed countries in the development of open control system with the fusion of PC. Turbotek, Hyundai Motor and Daewoo are leading companies, but their commercial possibility seems to be low because domestic market is too small to reap a commercial benefit. Nevertheless, the development of the system is an essential step for Korea to embark on a future technological paradigm of the machinery industry. The government needs to play some role for the development, for instance, government R&D projects, institutional building and training of related technicians.

• Knowledge Management Research
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• v.10 no.4
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• pp.43-60
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• 2009

The current study attempts to provide the field of knowledge management with theoretical grounds from the perspective of social network, resource dependency, and institutional theory. Social network theory considers that knowledge management plays a critical role in organizational innovation through the process of knowledge sharing/creation, communication systems, and a cooperative culture and trust, whereas resource dependency perceives knowledge management as contributing to cost reduction through the process of knowledge capture/storage, database systems, and reward/incentive systems. Plus, from the perspective of institutionalization, this study discusses that organizations can not benefit from knowledge management if it is adopted with the motive of isomorphic change. Finally, this study compares and integrates the three perspectives, and discusses the implications and limitations.

• Korean Journal of Clinical Laboratory Science
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• v.46 no.4
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• pp.124-130
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• 2014

The aim of this study undertook to ascertain the health levels and risk among petty merchants at some traditional markets by way of physical examination and laboratory tests. Data was collected through physical examination and laboratory tests on blood pressure, glucose, cholesterol, triglyceride, LDL cholesterol, and HDL cholesterol. The data was analyzed by Frequency analysis, T-test, One-Way ANOVA using the PASW statistics 18.0 program. By blood pressure on sex, male ($1.89{\pm}0.6$), female ($1.48{\pm}0.6$) appeared (p<0.001). Male levels were higher than in female levels. Additionally TG appeared male levels ($193.4{\pm}129.4$), female levels ($142.7{\pm}80.6$). Male levels were higher than in female levels (p<0.006). By blood pressure as the age increased in more than 70 (2.17) exhibited a statistically significant difference. These merchants did not practice health behaviors nor take institutional health management benefit. Therefore governmental level community based health management services are recommended for them.

• Journal of the Korea Society of Computer and Information
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• v.20 no.12
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• pp.175-180
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• 2015

It is important to maintain information system (IS) following the business and institutional change. Even if successfully developed information systems, we cannot gain the benefit from the systems without the proactive maintenance activities. However, the importance of IS maintenance has not been considered as much as the system development, and we don't have any specific performance management structure. The objective of this study is to identify the relationship between IS maintenance activities and utilization. For empirical test of the hypothesis model, the sample data is collected from public information system sites. Results from multiple regression analysis reveal that proactive maintenance activities including IS maintenance cost increase, improving functionality, and enhancing ease of use have a causal effect on the IS utilization.

• Proceedings of the Safety Management and Science Conference
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• 2009.11a
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• pp.495-505
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• 2009

Unpaid Family Worker is blind area of industry safety. Danger of industrial accident is some high but because was excepted in industrial accident compensation insurance application. In most case, because paltry Unpaid Family Worker is no opportunity to take safety education to prevent industrial accidents and there are few safety facility and safety equipment, etc., among business, it may be said that probability to suffer industrial accidents on a trifling mistake or carelessness is higher than general worker of business. Consider such difficult actuality of Unpaid Family Worker and our country must give these benefit of industrial accident compensation insurance application, as opened the door of insurance application in recognition of worker position by "Industrial accident compensation insurance Law" to middle·smaller enterprise's business proprietor or special form labor employees.

• KDI Journal of Economic Policy
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• v.42 no.4
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• pp.91-116
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• 2020

As a project appraisal tool, the preliminary feasibility study (PFS) has contributed to enhancing the efficiency of public investment decision-making in the Republic of Korea over the last two decades. To overcome the limitations of the efficiency-oriented cost-benefit analysis, the PFS accommodates equity concerns among regions, namely balanced regional development (BRD) analysis. This study attempts to gauge the contributions of BRD analysis to PFS results. Specifically, it addresses how effectively policy efforts to promote decision-making have been implemented in the PFS stage while also considering the balance between equity and efficiency in terms of the trade-off between them, the degree to which they influence the results, and whether the consideration of equity is in fact actually reflected in seriously underdeveloped regions as intended. The study finds that the PFS results over the last two decades have been largely in line with the background and policy objectives. Based on the findings of the study, needs for institutional improvement are suggested, including enhancements in the analysis of regional economic ripple effects and taking into account the psychological factors pertaining to the evaluators in the overall judgment.