• Title/Summary/Keyword: Institute of Medicine

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Anti-cancer effect of Eriocaulon sieboldianum through the activation of caspase-3 in human leukemia cell line, HL-60 cells

  • Kim, Su-Jin;Lee, Gi-Tak;Lee, Bo-Ra;Jeon, Kwon-Su;Rim, Hong-Kun;Bang, Jun-Ho;Kim, Yang-Gwi;Myung, No-Yil;Moon, Phil-Dong;Kim, Na-Hyung;Choi, In-Young;Choi, Young-Jin;Kang, In-Cheol;Um, Jae-Young;Hong, Seung-Heon;Kim, Hyung-Min;Jeong, Hyun-Ja
    • Advances in Traditional Medicine
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    • v.9 no.2
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    • pp.186-191
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    • 2009
  • Eriocaulon sieboldianum (ES) is used in traditional oriental medicine for various medicinal purposes including headache, toothache, and inflammation. However, the anti-cancer effect of the ES is still not fully understood. In the present study, the human leukemia cell line HL-60 was used to characterize the apoptotic effects of ES. ES induced cytotoxicity of HL-60 cells in a dose- and time-dependent manner. ES induced the generation of reactive oxygen species, and the release of cytochrome c in a dose-dependent manner. In addition, we showed that ES-induced apoptosis was accompanied by activation of caspase-3. Taken together, our results demonstrate that ES possesses anti-cancer activity in HL-60 cells.

Lymphocytic Gastritis in a Dog

  • Im, Tae-Kyun;Lee, Sun-Hee;Son, Sun-Ho;Lim, Soo-Jung;Jeong, Seong-Mok;Cho, Sung-Whan;Kim, Duck-Hwan;Song, Kun-Ho
    • Proceedings of the Korean Society of Veterinary Clinics Conference
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    • 2009.04a
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    • pp.261-261
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    • 2009
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A Case of Chronic Necrotizing Pulmonary Aspergillosis Obscured by Cavitary Pulmonary Tuberculosis (공동성 폐결핵으로 오인된 만성 괴사성 폐 아스페르길루스증 1예)

  • Min, Joo-Won;Yoon, Young Soon;Park, Jong Sun;Kim, Hye-Ryoun;Rhee, Ji young;Yoo, Chul-Gyu;Kim, Young Whan;Han, Sung Koo;Shim, Young-Soo;Yim, Jae-Joon
    • Tuberculosis and Respiratory Diseases
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    • v.63 no.4
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    • pp.368-371
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    • 2007
  • Pulmonary cavities are caused by bacterial pneumonia, fungal diseases, lung cancer, and tuberculosis (TB). However, in Korea, patients with cavitary lung lesions are generally considered to have pulmonary TB, where the incidence of TB is approximately 70/100,000 per year. We report a case of chronic necrotizing pulmonary aspergillosis that was obscured by multidrug-resistant pulmonary TB.

Primary Malignant Fibrous Histiocytoma of the Chest Wall Misdiagnosed as Traumatic Hemothorax

  • Hwang, Ki-Eun;Hwang, June-Seong;Kim, Kyung-Min;Jung, Jae-Wan;Oh, Su-Jin;Kim, Eun-Kyoung;Ryu, Dae-Woon;Choi, Keum-Ha;Jeong, Eun-Taik;Kim, Hak-Ryul
    • Tuberculosis and Respiratory Diseases
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    • v.76 no.6
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    • pp.289-291
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    • 2014
  • Malignant fibrous histiocytoma (MFH), a type of sarcoma, is a malignant neoplasm with uncertain origins that arise from both the soft tissues and the bone. The occurrence of MFH on the chest wall is extremely rare. We hereby report a case of a 72-year-old woman who was incidentally detected with MFH after a traffic accident.