• Genomics & Informatics
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• v.15 no.4
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• pp.123-127
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• 2017

Synonymous sites are generally considered to be functionally neutral. However, there are recent contradictory findings suggesting that synonymous alleles might have functional roles in various molecular aspects. For instance, a recent study demonstrated that synonymous single nucleotide polymorphisms have a similar effect size as nonsynonymous single nucleotide polymorphisms in human disease association studies. Researchers have recognized synonymous codon usage bias (SCUB) in the genomes of almost all species and have investigated whether SCUB is due to random nucleotide compositional bias or to natural selection of any functional exposure generated by synonymous mutations. One of the most prominent observations on the non-neutrality of synonymous codons is the correlation between SCUB and levels of gene expression, such that highly expressed genes tend to have a higher preference toward so-called optimal codons than lowly expressed genes. In relation, it is known that amounts of cognate tRNAs that bind to optimal codons are significantly higher than the amounts of cognate tRNAs that bind to non-optimal codons in genomes. In the present paper, we review various functions that synonymous codons might have other than regulating expression levels.

• KCID journal
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• v.21 no.1
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• pp.109-117
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• 2014

Multi water-loop system is the efficient customer centered facilities of water supply by utilizing the multi water resources. Multi water-loop system is divided into various types. The system is classified potable and non-potable type. Mostly, the potable type utilizes surface water and ground water. However, the non-potable type utilize the multi water resources, such as rain water, sea water, reclaimed water, etc. Selective intake is possible when characteristics of region, physiographic condition and purpose of use are considered. For instance, downtown type, new-city type, agriculture type, island type are available. For development and application of these multi water-loop system, standardization is needed. For standardization, several methods are given; design principles, selection and composition method of multi water-loop system structure, BIM/GIS application method, safety inspection method. Consequently, a road map of design standardization method can be established. In this road map, there are three parts for the standardization of multi water-loop system. Three parts are the considerations, base material and ways of standardization. Design standardization become close when this road map followed by someone who plan the multi water-loop system. In this way, loop system's development is more efficient and economic. In hereafter research, each type's characteristic will be analysed and standardization methods can be established.

• Journal of Distribution Science
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• v.15 no.12
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• pp.21-30
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• 2017

Purpose - This research approaches to the new niche market of medical tourism to investigate how factors of cultural similarity influence the international distribution management. This study also estimates the interaction effects of distribution channel on the relationships of facility attributes and customers' destination choice behavior. Research design, data, and methodology - We collected the sample of 881 potential customers from the more economically developed regions in China. Regression analysis is used to confirm the relationships in the research model. Results - The result shows that cultural similarity plays an important moderating role in the relationships of facility attributes and destination choice intention. For instance, power distance and masculinity interact with the distribution facility characteristics of medical quality and reputation to influence customers' selection of the destination country. Individualism, powder distance, and masculinity play moderating roles when social environment affects destination choice intention. Especially, all the elements of cultural similarity moderate the relationships between travel cost and destination choice intention. This research also proves that depending on distribution channel, determinants of distribution facility are the critical predictors of intention to select the medical service outside of China. Conclusions - The study enables managers to develop the more effective strategies reflecting the interaction effects of cultural similarity and distribution channel on customers' decision-making process.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.12
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• pp.1150-1159
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• 2011

Reliability is defined as a probability that a system will operate properly for a specified period of time under the design operating conditions without failure. Reliability-Redundancy Optimization Problem(RROP) involves selection of components with multiple choices, redundancy levels and redundancy strategy(Active or Standby) for maximizing system reliability with constraints such as cost, weight, etc. Based on the design configuration of Multi-Spectral Camera(MSC) system of KOMPSAT-2, the mathematical programming model for RROP is suggested in this study. Due to the nature of RROP, i.e. NP-hard problem, Parallel Particle Swarm Optimization(PPSO) algorithm is proposed to solve it. The result of the numerical experiment for RROP is presented as instance of recommended design configuration at some mission time.

• Convergence Security Journal
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• v.16 no.1
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• pp.39-48
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• 2016

In 1976, privative security law in Korea was enacted. Through the law has been revised 23 times, and it reflected changing security environment. Since the private security is now in charge of the daily safety as well as the police, private security law should be revised in overall dimension. First, the name of private security service and terms should be reorganized with applying the current environment of security. For instance, there should be an appropriate range of security service which could contain security consulting, planner, private investigator, and convergence security. Second, the errors of private security law should be corrected and applied to the revised law. Third, some inappropriate contents in the private security law should be revised. Forth, revising the private security law should consider to solve problems in selection, education, and election of security instructor.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.427-432
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• 2004

As it is keen competition of a construction market and the recognition that increases construction productivity for maintaining competitiveness, it is increased importance of an interest about productivity and efficiency in the construction industry. This study measures productivity through the instance of investigation that the existing productivity measurement method was utilized and presented a work improvement matter based on the measured contents. The proposed improvement matter is verified through a simulation technique. The purpose of this paper is for a field supervisor to have presented the way that a selection does the most suitable work method to be suitable for a situation, and can forecast production, though a simulation technique is not the most alternative that considered field condition in analyzing productivity measurement.

• Earthquakes and Structures
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• v.8 no.6
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• pp.1349-1362
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• 2015

This paper presents an analytical study aimed at evaluating the effectiveness of using buckling-restrained braces (BRBs) in mitigating the seismic response of a case study 6 storey reinforced concrete (RC) building. In the design of the BRBs with non-prismatic cross-sections, twelve combinations of ${\alpha}$ and ${\beta}$ design parameters that influence the strength and stiffness of the BRBs, respectively, were considered. The response of the structure with and without BRBs under earthquake ground accelerations were evaluated through nonlinear dynamic analysis. Two sets of ground motions representative of the design earthquake with 10% and 50% exceedance probability in fifty years were taken into account. By comparing the structural performance of the original and buckling restrained braced structures, it was observed that the use of the BRBs were very effective in mitigating the seismic response as a retrofit scheme. However, the selection of the strength and stiffness parameters of the BRBs had considerable effect on the response characteristics of RC structures. For instance, by increasing the value of ${\alpha}$ and by decreasing the value of ${\beta}$ of the buckling-restrained braces, the maximum deformation demand of the structures increased.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2005.05a
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• pp.255-256
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• 2005

For the students who specialize in interior design irrespective of their color susceptibility, it is prerequisite to precede a systematic curriculum in the first place on how to put the color theory to practical use. Therefore, this curriculum has its purpose to let the students study on how to put to practical use of their understanding of color as one of the finishing materials for interior design. The 16-weekschool days has been segmented into a theoretical study and practical training, This thesis has summed up the basic instance of the color theory, the first of the three basicpractical courses and presented its results to the students. In due course of this curriculum, the students were recommended to pick up one photo image of their selection out of which they could make out color palette based on their analysis of the photo image, so that they could study on how to apply their color palette to a three dimensional space. Firstly, through this course, they could experience the process for a color image that they had so far sensed subjectively and vaguely to become an objective inevitable result. Secondly, they studied on the process of how a two-dimensionalcolor image could be applied for a three-dimensional space. It is significant of this curriculum in the sense that the students become prepared through this study course with essential knowledge applicable to various interior designs in their future.

• International Journal of Computer Science & Network Security
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• v.21 no.9
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• pp.212-222
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• 2021

Multiple waves of COVID-19 highlighted one crucial aspect of this pandemic worldwide that factors affecting the spread of COVID-19 infection are evolving based on various regional and local practices and events. The introduction of vaccines since early 2021 is expected to significantly control and reduce the cases. However, virus mutations and its new variant has challenged these expectations. Several countries, which contained the COVID-19 pandemic successfully in the first wave, failed to repeat the same in the second and third waves. This work focuses on COVID-19 pandemic control and management in Saudi Arabia. This work aims to predict new cases using deep learning using various important factors. The proposed method is called Deep Learning and Dynamic Weighing-based (DLDW) COVID-19 cases prediction method. Special consideration has been given to the evolving factors that are responsible for recent surges in the pandemic. For this purpose, two weights are assigned to data instance which are based on feature importance and dynamic weight-based time. Older data is given fewer weights and vice-versa. Feature selection identifies the factors affecting the rate of new cases evolved over the period. The DLDW method produced 80.39% prediction accuracy, 6.54%, 9.15%, and 7.19% higher than the three other classifiers, Deep learning (DL), Random Forest (RF), and Gradient Boosting Machine (GBM). Further in Saudi Arabia, our study implicitly concluded that lockdowns, vaccination, and self-aware restricted mobility of residents are effective tools in controlling and managing the COVID-19 pandemic.

• Journal of architectural history
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• v.30 no.3
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• pp.33-44
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• 2021

San-ja is one of the main members consisting of the roof of traditional wooden buildings in Korea. In this study, the regional characteristics of the materials used in San-ja and changes of the materials over time were examined. To this end, 123 documents on the repair of wooden architectural heritage recorded since the 1950s were reviewed. It was found that there was a difference in the San-ja material by region because of the diversity in the conditions of material supply. For instance, bamboo was the most frequently used material in Jeollanam-do province because it was readily available. However, with the development of transportation and vehicle, the regional characteristics have disappeared. As a result, the material has been unified with bamboo now. This is because bamboo is specified as a representative material in the specification or the convenience of construction is prioritized. In addition, the social and economic conditions at the time of repair had an influence on the selection of the San-ja materials.