• Title/Summary/Keyword: Inorganic antibiotics

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An Experimental Study on Durability of Concrete Covered with Antibiotics (항균제를 도포한 콘크리트의 내구특성에 관한 실험적 연구)

  • Lee Eui-Bae;Lee Dong-Heck;Moon Hyung-Jae;Kim Jae-Hwan;Kim Gyu-Yong;Kim Moo-Han
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2005.11a
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    • pp.97-100
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    • 2005
  • Recently sewage facilities mainly consisted of concrete structures are being deteriorated seriously by biodeterioration originated from sulfur-oxidizing bacteria. In this study, to prevent biochemical corrosion of the sewer concrete, antibiotics which prevent the growth of sulfur-oxidizing bacteria were developed and antimicrobial performance of it was investigated. After that, to consider applicability of antibiotics to concrete, durability such as resistance to carbonation, salt damage and chemical attack of concrete covered with inorganic and complex antibiotics were investigated. As a result of this study, it was proved that the antimicrobial performance of antibiotics was available. Also resistance to carbonation, salt damage and chemical attack of concrete covered with inorganic antibiotics was little improved but, in case of complex antibiotics, was remarkably improved. Moisture content of concrete, as a application condition of antibiotics in whole case, have little effect on performance but covering times of antibiotics have effect on performance only in case of complex antibiotics.

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An Experimental Study on Development of Physical Properties and Durability of Concrete Spread with Inorganic Antibiotics (무기질 항균제 도포에 의한 콘크리트의 경화성상 및 내구성상 향상에 관한 실험적 연구)

  • Kim, Moo-Han;Khil, Bae-Su;Kim, Jae-Hwan;Cho, Bong-Suk;Lee, Eui-Bae
    • Journal of the Korea Institute of Building Construction
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    • v.5 no.3 s.17
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    • pp.75-82
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    • 2005
  • Sewage facilities are positively necessary for environment improvement such as rainwater removal, sewage disposal, preservation of the quality of water and health of the citizens in present-day. Meanwhile, a deterioration of the concrete sewer pipe is increasing rapidly due to the chemical and physical attack and especially biochemical attack that is to say biodeterioration. So, in advanced countries, prediction techniques and corrosion inhibition system for sewer concrete are developed and are being applied. Also, antibiotics were developed already but application of that is low because it is not economical and has no practical use. But, in domestic, countermeasures for the corrosion of sewage concrete are not sufficient and biochemical attack is not reflected in those essentially. In this study, to prevent biochemical corrosion of the sewer concrete, surface of the concrete was spread with liquefied inorganic antibiotics and then its engineering properties were experimentally investigated. As a result, compressive strength of the specimen spread with antibiotics were similar to those of non spread, Both bond strength and abrasion amount of the specimen spread with antibiotics were inferior to non spread. Properties of absorption and air permeability of the specimen spread with antibiotics were superior to non spread. Finally, carbonation depth, chloride ion penetration depth and weight change ration of the specimen spread with antibiotics were smaller than non spread.

An Experimental Study on the Fundamental Properties of. Sewage Concrete Covered with Inorganic and Complex Antibiotics (무기계 항균제 및 유$\cdot$무기계 복합 항균제를 도포한 하수시설 콘크리트의 기초물성에 관한 실험적 연구)

  • Lee Eui-Bae;Lee Dong Heck;Na Chul Sung;Khil Bae Su;Kim Gyu Yong;Kim Moo Han
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.11a
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    • pp.499-502
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    • 2005
  • Recently sewage facilities mainly consisted of concrete structures are being deteriorated seriously by biodeterioration originated from sulfur-oxidizing bacteria. In this study, to prevent biochemical corrosion of the sewer concrete, antibiotics which prevent growth of sulfur-oxidizing bacteria were developed and antimicrobial performance of it was investigated. After that, to consider applicability of antibiotics to concrete, physical properties such as bond strength, resistance to abraision, water absorption and air permeability of concrete covered with inorganic and complex antibiotics were investigated.

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Antibacterial Performance of Inorganic Liquified Antibiotics for antibacterial Concrete used in Sewage Facilities (하수시설에 사용되는 항균 콘크리트용 무기계 액상 항균제의 항균성능)

  • Kim Do Su;Khil Bae Su;Kim Gyu Yong;Lee Seung Hoan
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.05b
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    • pp.49-52
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    • 2005
  • This study was performed to evaluate antibacterial performance antibiotics(RCF-95, Antibio-C) which could control biochemical corrosion of concrete used sewage facilities by sulfate oxidizing bacteria. As antibacterial methods, Broth MIC testing was used for investigating controlled growth effect of sulfate oxidizing bacteria. Also, color-changed testing by indicator was used for confirming between $H_{2}SO_{4}$ diffusion rate by bacteria and antibiotics. It confirmed that Antibio-C was superior to RCF-95 in the antibacterial performance and hence anticipated that this developed Antibio-C was enough to replace imported antibiotics from Japan.

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An Experimental Study on the Physical Properties of Concrete Spread with Liquefied Organic and Inorganic Complex Antibiotics (액상 유·무기 복합 항균제를 도포한 콘크리트의 물리적 특성에 관한 실험적 연구)

  • Kim, Mu-Han;Kim, Jae-Hwan;Jo, Bong-Suk;Lee, Eui-Bae
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.10 no.2
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    • pp.67-75
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    • 2006
  • Recently sewage facilities mainly consisted of concrete structures are being deteriorated seriously by biodeterioration originated from sulfur-oxidizing bacteria. In this study, to prevent biochemical corrosion of the sewer concrete, antibiotics which prevent growth of sulfur-oxidizing bacteria were developed and antimicrobial performance of it was investigated. After that, to consider applicability of antibiotics to concrete, physical properties of concrete spread with antibiotics were investigated. As a results of the study, it was proved that the antimicrobial performance of antibiotics was available. Also compressive strength and bond strength of concrete didn't closely connected with antibiotics, and resistance to abrasion, water absorption and air permeability of concrete was improved remarkably by spraying with it.

An Experimental Study on the Engineering Properties of Concrete Spread with Liquefied Antibiotics (액상 항균제를 도포한 하수시설용 콘크리트의 공학적 특성에 관한 실험적 연구)

  • Lee Eui-Bae;Kim Yong-Duk;Cho Bong-Suk;Kim Jae-Hwan;Khil Bae-Su;Kim Moo-Han
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.05b
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    • pp.233-236
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    • 2005
  • Sewage facilities are positively necessary for environment improvement such as rainwater removal, sewage disposal, preservation of the quality of water and health of the citizens in present-day. Meanwhile, a deterioration of the concrete sewer facilities is increasing rapidly due to the chemical and physical attack and especially biochemical attack that is to say biodeterioration. In this study, to prevent biochemical corrosion of the sewer concrete, surface of the concrete was spread with liquefied organic and inorganic complex antibiotics and then its engineering properties were experimentally investigated

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Acidifier as an Alternative Material to Antibiotics in Animal Feed

  • Kim, Y.Y.;Kil, D.Y.;Oh, H.K.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.7
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    • pp.1048-1060
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    • 2005
  • Dietary acidifiers appear to be a possible alternative to feed antibiotics in order to improve performance of weaning pigs. It is generally known that dietary acidifiers lower gastric pH, resulting in increased activity of proteolytic enzymes, improved protein digestibility and inhibiting the proliferation of pathogenic bacteria in GI tract. It is also hypothesized that acidifiers could be related to reduction of gastric emptying rate, energy source in intestine, chelation of minerals, stimulation of digestive enzymes and intermediate metabolism. However, the exact mode of action still remains questionable. Organic acidifiers have been widely used for weaning pigs' diets for decades and most common organic acidifiers contain fumaric, citric, formic and/or lactic acid. Many researchers have observed that dietary acidifier supplementation improved growth performance and health status in weaning pigs. Recently inorganic acidifiers as well as organic acidifiers have drawn much attention due to improving performance of weaning pigs with a low cost. Several researchers introduced the use of salt form of acidifiers because of convenient application and better effects than pure state acids. However, considerable variations in results of acidifier supplementation have been reported in response of weaning pigs. The inconsistent responses to dietary acidifiers could be explained by feed palatability, sources and composition of diet, supplementation level of acidifier and age of animals.

Occurrence of Tetracyclines Resistant Bacteria in the Soil Applied with Livestock Manure Compost (가축분 퇴비 시용 농경지 내 Tetracyclines 내성균 분포 특성)

  • Kim, Song-Yeob;Kim, Jang Hwan;Kim, Sung Chul;Lee, Yong-Bok
    • Korean Journal of Environmental Agriculture
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    • v.33 no.4
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    • pp.409-413
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    • 2014
  • BACKGROUND: Large amount of veterinary antibiotics have been used in the livestock industry to prevent diseases and promote growth. These antibiotics are excreted through feces and urine in unchanged form and reach to agricultural fields via application of the livestock manure based composts. The purpose of this study was to evaluate the occurrence of tetracyclines-resistant bacteria in the soil received livestock manure compost for a long term. METHODS AND RESULTS: Tetracyclines (tetracycline TC, chlortetracycline CTC, and oxytetracycline OTC) resistance bacteria in the soil of rice-onion field applied pig manure compost (PM), in the soil of grass-rye field received cow manure compost (CM), and in the soil of rice field applied inorganic fertilizer (NPK) were determined. The soil received livestock manure composts clearly showed higher number of TC, CTC, and OTC resistance bacteria compared with the soil treated with inorganic fertilizer. The antibiotic resistant bacteria recovered appeared at 80 mg/L of tetracyclines was identified 1 specie, 6 genera 7 species, and 6 genera 7species in the soils received CM, PM, and NPK, respectively. The dominant resistant bacteria with the CM and PM application were Ochrobactrum and Rhodococcus. CONCLUSION: The application of livestock manure compost in the agricultural field is likely to contribute the occurrence of antibiotic resistance bacteria in the agricultural environment.

Nitrogen Assimilation of Hydrocarbon Producing Algae, Botryococcus braunii UTEX-572

  • Kim, Yoon-Jeong;Lee, Chan-Yong
    • Journal of Microbiology and Biotechnology
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    • v.2 no.4
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    • pp.255-259
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    • 1992
  • The effect of nitrate, nitrite and ammonia as inorganic nitrogen sources on the modulation of nitrogen metabolism of Botryococcus braunii UTEX.-572 has been studied under aeration. The primary process in the regulation of nitrogen metabolism by this alga has the nitrate uptake system. This uptake of nitrate operation was immediately inhibited by the presence of 0.5 mM of ammonium and reversed by 0.2∼0.3 mM ammonium. When cell were exposed to 5 mM of ammonium for 24 hours the activity of nitrate reductase became inactive.

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Synthesis and Physicochemical Studies on a Novel Cephalosporin, DWC-751 (신규 세파로스포린 항생제 DWC-751 합성과 물성연구)

  • 김명구;안상근;최영기;문치장;오세한;성무제;윤길중;신종만;김학형
    • Biomolecules & Therapeutics
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    • v.1 no.1
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    • pp.103-108
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    • 1993
  • The synthesis and physicochemical properties of a novel cephalosporin, DWC-751 are described. DWC -751, (6R , 7R)-7-[ (Z)-2-(2-aminothiazol-4-yl)-2- methoxyiminoacetamido]-3-[(1-methylbenzotriazol-3-ium) methyl]-ceph-3-em-4-carboxylate monosulfate($IV_{\alpha}$) was conveniently obtained by the conversion of compound (IV) into the crystalline monosulfate. Adjusting pH 4.8-5.2 in aqeous solution of the crude crystalline, compound(IV) in the form of a crystalline pentahydrate was prepared with a high degree of purity. The influence of the various organic and inorganic acids on the solubility of compoud(IV) and its salts, was examined. Particularly, the solubility of DWC-751 was 92 mg/mι at pH 1.7 and 233 mg/mι at pH 3.0. DWC-751 showed a broad antimicrobial spectrum against gram-positive and negative bacteria.

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