• Title/Summary/Keyword: Innovator

Search Result 56, Processing Time 0.034 seconds

The Pharmaceuticals Regime in the KORUS FTA and the TPP Agreement: A Comparative Analysis (한미FTA와 TPP협정의 비교분석을 통한 의약품 분야 국제통상규범에 대한 연구)

  • Yun, Mikyung
    • International Commerce and Information Review
    • /
    • v.18 no.4
    • /
    • pp.165-193
    • /
    • 2016
  • This paper conducts a comparative analysis of the KORUS FTA and the TPP Agreement to assess the current state of affairs in international trade rules for the pharmaceutical industry. Intellectual property rights as well as public health related regulations have evolved to strengthen the position of innovator drug companies. In particular, the TPP Agreement which adopted data exclusivity for biologics for the first time, will set the standard for the future. Apart from this however, the TPP Agreement has not gone further than the KORUS FTA and in some respects, even contains greater policy flexibilities and provisions for market access than the KORUS FTA. Korea should take advantage of such differences when and if she must engage in negotiations to join the TPP Agreement or a renegotiation of the KORUS FTA.

  • PDF

Bioequivalence of Sinil Atenolol Tablets to Tenormin Tablets (Atenolol 50 mg) (테놀민 정(아테놀올 50 mg)에 대한 신일아테놀올 정의 생물학적 동등성)

  • Gwak, Hye-Sun;Kang, Sung-Ha;Chun, In-Koo
    • Journal of Pharmaceutical Investigation
    • /
    • v.33 no.1
    • /
    • pp.51-53
    • /
    • 2003
  • This study was conducted to compare the bioavailability of a generic product of Sinil Atenolol Tablets (Sinil Pharmaceutical Co., Ltd., Korea) with the innovator product, $Tenormin^{\circledR}$ Tablets in 20 healthy Korean volunteers. The volunteers received a single 50 mg dose of each atenolol formulation according to a randomized, two-way crossover design. Plasma samples were obtained over a 24-hour interval, and atenolol concentrations were determined by HPLC with a fluorescence detector. From the plasma atenolol concentration vs time curves, the following parameters were compared: area under the plasma concentration-time curve (AUC), peak plasma concentration $(C_{max})$, time to reach peak plasma concentration $(T_{max})$, and terminal first order elimination half-life $(t_{1/2})$. No statistically significant difference was obtained between the $T_{max}$ values, and the logarithmic transformed AUC and $C_{max}$ values of the two products. The 90% confidence for the ratio of the logarithmically transformed AUC and $C_{max}$ values of Sinil Atenolol Tablets over those of $Tenormin^{\circledR}$ Tablets were calculated to be between 0.99 and 1.07, and 1.04 and 1.16, respectively; both were within the bioequivalence limit of 0.80-1.25. The mean of $T_{max}$ in $Tenormin^{\circledR}$ Tablet group was 3.68 hour, and that in Sinil Atenolol Tablet group was 3.65 hour. The values of $t_{1/2}$ between the two products were found comparable, and the mean $t_{1/2}$ values of $Tenormin^{\circledR}$ Tablets and Sinil Atenolol Tablets were 5.9 and 6.0 hour, respectively. Based on these results, it was concluded that Sinil Atenolol Tablets were comparable to $Tenormin^{\circledR}$ Tablets in both the rate and extent of absorption, indicating that Sinil Atenolol Tablets were bioequivalent to the reference product, $Tenormin^{\circledR}$ Tablets

A Case Study of Discontinuous Innovation Based on Cusp Catastrophe Model : Implications for Predictive Risk Management (첨점 격변 모형에 기반 한 불연속 혁신의 유형별 사례 연구: 예측적 위기관리 측면)

  • Kim, Sung-Cheol;Shin, Minsoo
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.14 no.5
    • /
    • pp.2140-2149
    • /
    • 2013
  • Managing uncertainty or discontinuity in an innovation is still a challenge to most companies. For sustainable corporate survival over the long term, one of the problems caused by discontinuous innovation is the innovator's dilemma. In specific, the dynamics between discontinuous innovation and incumbents inspires the interestof researchers and managers. This paper employs catastrophe theory as a theoretical basis to explain the driving force of new discontinuous change. In other words, we extract the control variables overcoming innovation dilemma by interpreting the dynamics of corporate strategy for discontinuous innovation from the perspective of catastrophe theory. First, we define four types of discontinuity such as technology discontinuity, product discontinuity, business discontinuity, and consumer preference discontinuity. Second, we analyze the dynamics of the competition between companies by interpreting the cases of discontinuous innovation. This analyzing process enables us to identify the control variable which can, in advance, respond to the discontinuous situation.

An Empirical Examination of the Relationship between Service Level and Service Innovation based on Service Science (서비스사이언스를 기반으로한 서비스 수준과 서비스 혁신간의 관계에 대한 실증 연구)

  • Kim, Yong-Jin;Yim, Myung-Seong
    • Journal of Digital Convergence
    • /
    • v.11 no.6
    • /
    • pp.73-90
    • /
    • 2013
  • Our basic objective in this paper is to identify a relationship among services, technology level, and service innovation activities using service science approach. The empirical tests are two-fold: first, to find out a difference in the level of service innovations, depending on the service levels and vice versa; second, to investigate the relationship between technology level and service activities and between technology level and service innovation activities. The results of the study are as followed: (1) Service innovation activities are different depending on service activities. (2) Service activities are different depending on service innovation activities. (3) Differences between technology level and service activities and between technology level and service innovation activities do not exist. These findings have implications for both research and practice.

Study on the Influence that the Japanese Fashion has had on the Contemporary Fashion(Focusing on the since 1980s) (일본 패션이 현대 패션에 미친 영향-(1980년대 이후를 중심으로)-)

  • 정성혜
    • Journal of the Korean Society of Costume
    • /
    • v.25
    • /
    • pp.21-39
    • /
    • 1995
  • By 1980, there are two main flows in the world fashion. One is the traditional Paris fashion by Houte Couture, and the other is the American casual fashion by mass production. However, the appearance of Japanese designers and their new styles on the stage of Paris fashion have had a strong influence on the change of the world fashion since 1980s. So, the purposes of this study were first to research the process, the background and the power which let the Japanese stand and suc-ceed in the stage of Paris fashion, second to research on the Fashion World and Fashion Trend from the beginning of 1980s to present (1994). The results were as follow ; Hanae Mori and Kenzo were the pioneers who let the West know the existence and the level of Japanese fashion. Issey Miyake was the new innovator in the 20th century Fashion. and became the foundation of the New Wave Fashion in 1980s. Rei kawakubo completed the philosophy of beauty by the imperfection and has led the Postmodernism in the Fashion. The constant efforts of the these Japanese designers have inspired the orientalism and Art-to Wear, showed up the new construction and material in clothing by layering and drap-ing and stimulated the traditional Paris fashion to become popular, casual and diverse. The success of Japanese designers and the boom of Japanese fashion were not only the effort of individuality but also the power of economics, the spirit of cooperation and the affection to the culture and tradition on the background. The New Wave fashion by Japanese designers in the beginning of 1980s have promoted the appearance of Avant-garde fashion in London, the new fashion spirit in Milano, and the various fashion styles of different sections in the West and East. Finally, it becomes popular in 1990s and leads the fashion spirit in the end of 20th century.

  • PDF

Exploring of the Sustainability for the Educational Community in Rural Area (농촌지역 교육공동체의 지속가능성 탐색)

  • Kim, Jin Hee;Kwon, Su Bin
    • The Korean Journal of Community Living Science
    • /
    • v.27 no.spc
    • /
    • pp.651-663
    • /
    • 2016
  • This study explores the background and the processes underpinning the educational reform movement based on local community. This educational community initiated the alternative education reform movement, which is referred to as the small school movement. A qualitative case study was implemented by collecting data from thirty articles, three focused interviews. This study drew out three key factors as the operation of educational community in regional area. First, it claimed a total of 30 papers related to the educational community for content analysis. Second, key words were derived in the local educational community context. They developed their own alternative educational programs, such as self-supportive meeting, season carnivals, community revitalization activities, and so on. Their focus was on finding out and establishing better educational relationships among the concerned communities. Third, the community continues to reinforce the internal rules and climate through meta-education, a process, in which education educates itself. As a result, they could enjoy substantial success in a visible educational community. This small school revival movement later grew into the new school movement. Furthermore, a variety of teachers, parents groups, and interested scholars have been engaged in the community movement through professional networking. This study suggests that the key innovator-initiated movement, which involves education reform, upgraded Korean education, and improved their own expertise and autonomy, is expected to be the first step to solve the current Korean educational problems by the educational community.

The Origin of K orean Online Game Industry : Networks of 'Butterflies' (한국 온라인 게임 산업의 기원 : '나비들'의 네트워크)

  • Nam, Young
    • Journal of Science and Technology Studies
    • /
    • v.11 no.2
    • /
    • pp.1-30
    • /
    • 2011
  • This paper analyzes system builders and their human networks of the Korean online game industry. By the early 2000s, Korea became one of the major online gaming countries in the world. In this period, important factors included the existence of system builders and their solid human networks. The few innovators who assisted the breakthrough of the development of the online gaming industry formed a human network in universities and IT companies. They shared innovations in information and collectively learned the conventions of the industry. In their achievement, the human networks which had already fully formed in the late 1990s became more noticeable. This paper, with its historical approach, will complement the limits shown by existing researches that, in their effort to find the causes for the success of the Korean online game industry, focus rather narrowly on the conditions of the period during which online games were becoming popular.

  • PDF

Bioequivalence Evaluation of Two Atenolol Tablet Preparations in Korean Healthy Male Volunteers

  • Gwak, Hye-Sun;Chun, In-Koo
    • Biomolecules & Therapeutics
    • /
    • v.15 no.3
    • /
    • pp.187-191
    • /
    • 2007
  • This study was conducted to compare the bioavailability of two brands of atenolol (50 mg) tablets, which are a generic product of $Ditent^{\circledR}$ (Daewon Pharmaceutical Co., Ltd., Korea) and an innovator product $Tenormin^{\circledR}$ (Hyundai Pharm. Ind. Co., Ltd., Korea), in 20 healthy Korean male volunteers. The volunteers received a single 50 mg dose of each atenolol formulation according to a randomized, two-way cross-over design. The washout period between treatments was 1 week. Plasma samples were obtained over a 24-hour interval, and atenolol concentrations were determined by HPLC with a fluorescence detector. From the plasma atenolol concentration vs. time curves, the following parameters were compared: area under the plasma concentration-time curve ($AUC_{0-24}$), peak plasma concentration ($C_{max}$), time to reach peak plasma concentration ($T_{max}$), and terminal first order elimination half-life ($t_{1/2}$). No statistically significant difference was obtained between the $T_{max}$ values, and the logarithmic transformed $AUC_{0-24}$ and $C_{max}$ values of the two products. The 90% confidence interval for the ratio of the logarithmically transformed AUC and $C_{max}$ values of $Ditent^{\circledR}$ over those of $Tenormin^{\circledR}$ were calculated to be between 0.85 and 1.04, and 0.89 and 1.07, respectively; both were within the bioequivalence limit of 0.80-1.25. The mean of $T_{max}$ in $Tenormin^{\circledR}$ group was 3.1 hour, and that in Ditent$^{\circledR}$ group was 3.2 hour. The values of $t_{1/2}$ between the two products were found comparable, and the mean values were 5.2 hour in the both products. Based on these results, it was concluded that $Ditent^{\circledR}$ was comparable to $Tenormin^{\circledR}$ in both the rate and extent of absorption, indicating that $Ditent^{\circledR}$ was bioequivalent to the reference product, $Tenormin^{\circledR}$.

The Actual Conditions of Cosmetics Purchasing and Evaluation Criteria According to Men's Fashion Leadership (남성의 유행선도력에 따른 화장품 구매실태와 평가기준)

  • Park, Eunhee
    • Journal of Fashion Business
    • /
    • v.17 no.5
    • /
    • pp.84-100
    • /
    • 2013
  • The purpose of this study is to classify men's fashion leadership into groups and analyzed the differences for the actual conditions of cosmetics purchasing and evaluation criteria. Questionnaires are being administered from 163 men in their 20's and 30's living in Deagu Metropolitan City and Kyungbook. Frequency, factor analysis, reliability analysis, cluster analysis, ANOVA, Duncan-test, and $X^2$-test are all used for data analysis. Our findings are as follows. Men's fashion leadership is being categorized into fashion opinion leadership, innovative communicator and fashion innovator. Cosmetics evaluation criteria are service/aesthetic, ostentatious, function, and economy. Men's fashion leadership is classified into three groups: fashion laggards, fashion leaders, and fashion followers. Males show no significant differences in the function of cosmetics evaluation criteria by the groups but they show significances in service/aesthetic, ostentatious, and economy. Groups display distinctions between the sub-variables in the actual condition of cosmetics purchasing such the place of purchase, companionship when buying cosmetics, and average monthly purchase amount. Although the cosmetic markets for men show high average growth rates per year, cosmetic interests at the age of twenties and thirties are generally low, and cosmetics are not actively used. The customers' experience of using merchandise not only provide the opportunities of trying beforehand, but also lead to the role of information transfer, thus, it can be positively applied to active marketing. In addition, it can be expected that the low-priced cosmetic markets are guaranteed to obtain loyal customers through repurchasing and maintain long-term relationships by providing fashion followers with several promotional events.

Imitation as a Viable Strategy: The Case of Ediya in Korean Coffee Franchise Industry (모방전략의 유용성에 관한 연구: 이디야 사례)

  • Choi, Jin-Ah
    • Journal of Distribution Science
    • /
    • v.15 no.6
    • /
    • pp.47-56
    • /
    • 2017
  • Purpose - The purpose of this study is to examine the viability of imitation strategy. Imitation strategy is one of the strategic options that a late mover can choose, and by selecting the strategy, the company imitates key elements of the business model of first movers, and modifies them to suit its conditions. The author attempted to explain how the elements of first mover's business models were creatively adapted to suit the conditions of late movers so that they can secure market position face-to-face market leaders. Research design, data, and methodology - For the purpose of the study, Korean coffee franchise industry was selected to compare the strategies of first and late movers and to discuss imitation strategy in detail. The author conducted in-depth case study of first mover and business model innovator Starbucks and Ediya Coffee, one of their imitators. The paper examines how Ediya has imitated and modified the business model of Starbucks to secure its unique competitive position in domestic market by using value chain and generic strategy analysis. Results - Starbucks and Ediya were compared in terms of their interior design, the price level of beverages, the variety of side dishes, and shop locations. Starbucks have invested interior design heavily to shops, offered diverse beverages and side dishes with relatively high price, the shops are located in central areas, whereas Ediya has concentrated on achieving cost leadership in all value activities as maintaining the quality of key products. Ediya succeeded in achieving best-provider strategy, in which it enjoys both cost leadership and differentiation advantages, largely by the strategic alliance with the biggest coffee manufacturer, Dongsuh Foods in Korea. Conclusions - Though Ediya is the imitator of Starbucks, it has modified Starbucks business models and succeeded in providing the 'third place' experience for budget-minded customers. Ediya has also succeeded in benefiting its franchisees by lowering costs and simplifying the various tasks of coffee shop management. Due to these factors, Ediya could become one of the largest number shops as the coffee franchise in Korea.