• Journal of the Korean Society of Clothing and Textiles
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• v.12 no.3 s.28
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• pp.309-318
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• 1988

The purposes of this study were: 1) to develop specific AIO variables(clothing variables) based on clothing behavior studies, 2) to segment apparel market by clothing variables, 3) to discribe the profile of each segment with clothing variables, lifestyle variables and demographic variables, 4) to Suggest effective strategies on apparel market of women's clothing. The Likert Type clothing questionnaires measured 6 aspects of clothing (fashion, conformity-individuality, practicality, aesthetics, modesty and brand consciousness & status symbols) dealing with activities, interests and opinions. In addition, lifestyle variables were measured with general AIO statements. The questionnaires were administered to 563 young women (students, career women and homemakers) living in Seoul. The data were analysed by factor analysis, ctustering analysis, multiple discriminant analysis, one-way ANOVA ana Duncan's multiple range test. The results of the study were as follow: 1) 4 factors emerged from factor analysis of clothing variables. Factor 1: lower interest in modesty and higher interest in aesthics, Factor 2: brand consciousness and status symbols, Factor 3: conformity, Factor4 : fashion. 2) Lifestyle variables clustered into 3 factors. Factor 1: positive social activity, Factor 2: family-oriented type, Factor S: materialism. 3) By cluster analysis of the 4 factors of the clothing variables, the apparel market of women's clothing was categorised into 3 segments (innovative aesthetics seeker group, brand and status symbols conscious group, clothing unconscious group). 4) The above three segmented groups were also significantly discriminated by lifestyle and demosraphic variables. 5) On the basis of the findings, effective marketing strategies of women's clothing were suggested.

• Korean Institute of Interior Design Journal
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• v.27 no.1
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• pp.109-116
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• 2018

Prairie style houses in first stages of Frank Lloyd Wright's architecture activity pay a leading role in the process of house modernization as reflecting social and economic circumstances of the time based on traditional house style of the States. Wright's first work after retiring from L. Sullivan's office, Winslow house in 1983 is pioneering work predicting prairie house. This is because this house has only one modern architecture language of Wright and follow no style prevailing of the time. So, a researcher analyse Winslow house within the framework of functional thinking and new formative value creation in the modernization process of western house. Through this, The goal of this study is to find out modern characteristics and the meaning of Winslow house in modernization process prior to the 1900s. Firstly, the followings are modern characteristics of Winslow house. First, Winslow house has original planning breaking from custom based on modern functional and reasonable thoughts, and has practical space reflecting resident's inner demand. Second, Winslow house has modern new plastic value through original exterior breaking from custom and integrated shape of inner-outer space and structure. Secondly, the followings are the meaning of Winslow house in modernization process prior to the 1900s. First, Wright intend to suggest directions of residence modernization through Winslow house before designing Prairie style houses in earnest. Second, mixing of modern vocabulary and eclecticism show a sign of residence modernization process on the time. Third, inner-outer flowing space, opening space concept of Winslow house has innovative meanings predicting spacial characteristics of modern architecture.

• Transactions of the Korean Society of Automotive Engineers
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• v.20 no.4
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• pp.142-149
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• 2012

The reduction characteristics of $NO_2$ to NO are experimentally studied over a platinum-based catalyst, especially at lower temperatures below about $200^{\circ}C$. In the present work, two types of steady-state experiments, engine bench and synthetic gas bench tests, are carried out in sequence. Steady-state engine bench tests with the DOC mounted on a light duty 4-cylinder 2.0 liter turbocharged diesel engine are performed and prove that CO plays a major role in $NO_2$ abatement at temperatures below the light-off temperature of CO oxidation, about $200^{\circ}C$. Synthetic gas bench tests are then performed using synthetic gas mixtures with CO, $C_3H_6$, NO, $NO_2$, $O_2$, $H_2O$ and $N_2$ in the $140{\sim}450^{\circ}C$ T-range and show that both CO and $C_3H_6$ are capable of reducing $NO_2$. It is noted that the reaction rate of $NO_2$ with $C_3H_6$ is much higher than that with CO. At temperatures below about $200^{\circ}C$, the reduction of $NO_2$ to NO is promoted with increasing CO concentration and $NO_2$/$NO_X$ ratio and with decreasing $O_2$ concentration, as well as with the presence of $H_2O$.

• Quality Improvement in Health Care
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• v.19 no.1
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• pp.30-42
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• 2013

Objectives: This study was intended to check if the "Creating Clean Wards" project, which is an innovative reinforced campaign activity targeting infection control strategies and active surveillance cultures for VRE (vancomycin resistant enterococci) high-risk patients to be admitted in the NS (neuro-surgery) wards, would be reduced the incidence rates of VRE acquisition, transmission rates. Methods: 75 subjects of the VRE high-risk patients were surveyed by carrying out active surveillance cultures of VRE colonization 11 times from January to March, 2012. And the retrospective study was conducted dividing them into two groups. Results: The incidence rates of VRE acquisition was reduced to 3.67 cases per 1,000 patients day in the control group and to 2.88 cases in experimental group, which was not statistically significant (p = .753). VRE transmission rates of 0.0015 per day before the project tended to increase to 0.0019, although not statistically significant (p = .650). As a result of multivariate analysis with regard to using glycopeptide antibiotics in order to find out risk factors of VRE colonization, the patients who had been treated with glycopeptide until VRE colonization showed 274.41 times higher rate. Conclusion : For effective VRE infection control in NS wards, We should carry out active surveillance culture regularly, especially patient of using glycopeptide. And block the spread of VRE by strengthening infection control through the strict isolation and the changed mind-set of members motivated by the "Creating Clean Wards" campaign.

• Journal of Microbiology and Biotechnology
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• v.16 no.5
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• pp.651-660
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• 2006

Natural products are a rich source of biologically active small molecules and a fertile area for lead discovery of new drugs [10, 52]. For instance, 5% of the 1,031 new chemical entities approved as drugs by the US Food and Drug Administration (FDA) were natural products between 1981 and 2002, and another 23% were natural product-derived molecules [53]. These molecules have evolved through millions of years of natural selection to interact with biomolecules in the cells or organisms and offer unrivaled chemical and structural diversity [14, 37]. Nonetheless, a large percentage of nature remains unexplored, in particular, in the marine and microbial environments. Therefore, natural products are still major valuable sources of innovative therapeutic agents for human diseases. However, even when a natural product is found to exhibit biological activity, the cellular target and mode of action of the compound are mostly mysterious. This is also true of many natural products that are currently under clinical trials or have already been approved as clinical drugs [11]. The lack of information on a definitive cellular target for a biologically active natural product prevents the rational design and development of more potent therapeutics. Therefore, there is a great need for new techniques to expedite the rapid identification and validation of cellular targets for biologically active natural products. Chemical genomics is a new integrated research engine toward functional studies of genome and drug discovery [40, 69]. The identification and validation of cellular receptors of biologically active small molecules is one of the key goals of the discipline. This eventually facilitates subsequent rational drug design, and provides valuable information on the receptors in cellular processes. Indeed, several biologically crucial proteins have already been identified as targets for natural products using chemical genomics approach (Table 1). Herein, the representative case studies of chemical genomics using natural products derived from microbes, marine sources, and plants will be introduced.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.6
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• pp.357-362
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• 2015

A novel $TiO_2$-Coconut Shell Powder Composite (TCSPS), prepared by the controlled sol-gel method with subsequent heat treatment, was evaluated as an innovative photocatalytic absorbent for the removal of methylene blue. Optimal preparation conditions of TCSPC were obtained by a response surface methodology and a central composite design model. As compared with the results obtained from one-factor-at-a-time experiments, the values were approximated to the nearest condition of these values and the following experimental parameters were set as the optimum : $600^{\circ}C$ calcination temperature and 20 g of coconut shell powder loading amount.

• STI Policy Review
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• v.6 no.2
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• pp.54-86
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• 2015

The study examines the U.S. Small Business Innovation Research (SBIR) program, with a focus on the recent Reauthorization, and compares, in the political context, the U.S. and East Asian countries-Japan, Korea and Taiwan-that adopted the U.S. SBIR program. For the systematic analysis and cross-country comparison, the study employs Kingdon (2003)'s framework-his political theory and Garbage Can Model-to identify political participants and processes underlying the SBIR Reauthorization and to analyze the differences in problem, policy, and politics streams between the U.S. and East Asian countries. For the cross-country comparison, specifically, the study uses various data sources such as OECD, Global Entrepreneurship Monitor, Hofstede's Cultural Dimensions, and World Value Survey. Based on the analysis outcomes, implications of U.S. practices on East Asian countries are extracted as follows. East Asian countries tend to: Have higher entrepreneurial aspiration while lower entrepreneurial activity and attitude than the U.S.; bear higher long term orientation and uncertainty avoidance while lower individualism than the U.S.; and have greater expectations of technology development and higher confidence in political parties while participating less in political action than the U.S. Drawing on the differences, the following policy recommendations are suggested. East Asian countries should: Improve entrepreneurs' access to resources (in particular, financial resource) in order to link their high entrepreneurial aspiration to actual entrepreneurial activities; cultivate failure-tolerating culture and risk-taking entrepreneurs, for instance, by providing a second chance to SBIR-participating businesses that failed to materialize their innovative ideas; and leverage their high expectations of new technology in order to take bold actions regarding their SBIR programs, and update the programs by drawing out constructive dialogues between SBIR stakeholders.

• Journal of Technology Innovation
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• v.18 no.2
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• pp.147-174
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• 2010

This paper aims to analysis sectoral innovation patterns of technological innovation and localized knowledge spillover in Korean manufacturing sector. Sectoral innovation system approach proposed that the specific pattern of innovative activity and knowledge spillover in an industry can be explained as the outcome of different technological regimes. Technological regime is defined by the particular combination of technological opportunities, appropriability of innovations, cumulativeness of technical advances and properties of the knowledge base. Based on a sample of 2,882 firms in manufacturing sector, this paper provides empirical estimates of the relationships between firm's product innovation and localized knowledge spillover. Results of the analysis provide considerable support to the hypothesis that firm's product innovation and localized knowledge spillover are related to the nature of the underlying technological regime. In the industry based on the tacit and specific knowledge, firm's product innovation is positively related to the localized knowledge spillover. This paper also shows that high stability in the ranking of innovators are related to high degrees of cumulativeness and appropriability.

• Journal of The Korean Association of Information Education
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• v.22 no.2
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• pp.263-274
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• 2018

Maker movement is a part of open source making that originated from DIY culture and means production activity through combination of hardware and software as information and communication technology develops. The purpose of this study is to analyze the status and trends of the making movement in the world and to design a framework for the activation of making education. In this study, we developed the framework to spread the making culture by analyzing the current status and trends of making education, and suggested how to adapt the framework for making eduction in classroom. In addition, we analyzed the cases to suggest how making space should be constructed, and pointed the ideal way out to organize the making space.

• The Korean Journal of Nuclear Medicine
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• v.38 no.2
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• pp.161-170
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• 2004

Molecular Nuclear Neuro-Imaging in "CNS" drug discovery and development tan be divided into four categories that are clearly inter-related.(1) Neuroreceptor mapping to examine the involvement of specific neurotransmitter system in CNS diseases, drug occupancy characteristics and perhaps examine mechanisms of action;(2) Structural and spectroscopic imaging to examine morphological changes and their consequences;(3) Metabolic mapping to provide evidence of central activity and "CNS fingerprinting" the neuroanatomy of drug effects;(4) Functional mapping to examing disease-drug interactions. In addition, targeted delivery of therapeutic agents could be achieved by modifying stem cells to release specific drugs at the site of transplantation('stem cell pharmacology'). Future exploitation of stem cell biology, including enhanced release of therapeutic factors through genetic stem cell engineering, might thus constitute promising pharmaceutical approaches to treating diseases of the nervous system. With continued improvements in instrumentation, identification of better imaging probes by innovative chemistry, molecular nuclear neuro-imaging promise to play increasingly important roles in disease diagnosis and therapy.