• Title/Summary/Keyword: Innovation in S&T

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Homocysteine levels are associated with diabetes mellitus in Chinese with H-type hypertension

  • Dejian Fu;Wanbao Gong;Xiaomin Bao;Bo Yang;Feng Wang;Yubing Qiao;Yuanjiang Wu;Guangzhen Chen;Weixun Sun;Qiongzhi Xiao;Wenbo Zou;Ning Fang
    • Nutrition Research and Practice
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    • v.18 no.4
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    • pp.511-522
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    • 2024
  • BACKGROUND/OBJECTIVES: The study examined the association between homocysteine and diabetes mellitus in patients with H-type hypertension and assessed the possible effect modifiers. SUBJECTS/METHODS: This cross-sectional study included 1,255 eligible participants in the 'H-type Hypertension Management and Stroke Prevention Strategic International Science and Technology Innovation Cooperation Project' among rural Chinese people with H-type hypertension. A multivariate logistic regression model was used to evaluate the relationship between homocysteine and diabetes mellitus. RESULTS: The mean level of total homocysteine (tHcy) in the diabetes mellitus population was 19.37 μmol/L, which was significantly higher than the non-diabetic patients (18.18 μmol/L). When tHcy was analyzed as a continuous variable, the odds ratio (OR) of diabetes was 1.17 (95% confidence interval [CI], 1.01-1.35; per interquartile range). When tHcy was stratified according to the quintile, the ORs for diabetes were 2.86 (95% CI, 1.22-6.69) in the highest quintile (tHcy ≥ 20.60 μmol/L) compared to the reference group (tHcy < 12.04 μmol/L). When tHcy was grouped by 15 μmol/L and 20 μmol/L, patients with tHcy ≥ 20 μmol/L had a significantly (P = 0.037) higher risk of diabetes (OR, 2.03; 95% CI, 1.04-3.96) than in those with tHcy < 15 μmol/L. Subgroup analysis showed that the tHcy-diabetes association was unaffected by other variables. CONCLUSION: In this study of rural Chinese people with H-type hypertension, the tHcy levels showed a positive association with diabetes mellitus. This independent association is unaffected by other potential risk factors.

A Study on the Science and Technology Level in Korea (우리나라의 과학기술수준조사에 관한 연구)

  • 정근하;김인호;정한수
    • Proceedings of the Korea Technology Innovation Society Conference
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    • 1999.11c
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    • pp.219-236
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    • 1999
  • This study is to acquire a thorough understanding of the S&T level of Korea to serve as an important basis for the government policy-making, and to make basic information available to effectively promote the National R&D Program by survey of the overall S&T level in Korea S&T level survey is a comparison to the highest levels in the world to the third 3digit of the technology tree table. And, survey of technological gaps by year, during which Korea is able to reach the current level of the advanced countries. The findings of the surveys should be applied to strategic technology Planning for solving or narrowing the technology gap, e the major criteria for resources allocation in National R&D programs. And, the findings of the surveys should be the fundamental information used to establish strategic S&T policy in government.

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The Development and The Current Condition of Home Economics in China (중국 가정학회 발달과 현황)

  • 문숙재;조성은
    • Journal of the Korean Home Economics Association
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    • v.37 no.2
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    • pp.73-84
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    • 1999
  • There are a lot of thoughts and ideas for home, family and household in China. These thoughts and ideas hand down to posterity through classics. But, Home Economics in China doesn't have been condition of development. Home Economics in China regularly began to develop from the department of Home Science in a Women's College in SangHae. Talking this opportunity, there were departments of Home Science in many universities and colleges 1919 to 1930. But, the studies of Home Economics was discontinue by The Revolution of Culture. In that time, Home Economics was considered as a false science. In 1979, Home Economics in China began again after enforcement of the Innovation and The Open Door Policy. But up to the present it isn't systematically made up of the studies and the scientific papers of Home Economics. The department of Home Economics is only one in the College of Gillim-Agriculture. But, the objects of study in Home Economics include not only women but also men in China. Also, Home Economics in China is started first in Socialism Countries.

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STP Development in the Context of Smart City

  • Brochler, Raimund;Seifert, Mathias
    • World Technopolis Review
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    • v.8 no.2
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    • pp.74-81
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    • 2019
  • Cities will soon host two third of the population worldwide, and already today 80% of the world energy is used in the 20 largest cities. Urban areas create 80% of the greenhouse gas emission, so we should take care that urban areas are smart and sustainable as implementations have especially here the greatest impact. Smart Cities (SC) or Smart Sustainable Cities (SSC) are the actual concepts that describe methodologies how cities can handle the high density of citizens, efficiency of energy use, better quality of life indicators, high attractiveness for foreign investments, high attractiveness for people from abroad and many other critical improvements in a shifting environment. But if we talk about Entrepreneurship Ecosystem and Innovation, we do not see a lot of literature covering this topic within those SC/SSC concepts. It seems that 'Smart' implies that all is embedded, or isn't it properly covered as brick stone of SC/SSC concepts, as they are handled in another 'responsibility silo', meaning that the policy implementation of a Science and Technology Park (STP) is handled in another governing body than SC/SSC developments. If this is true, we will obviously miss a lot of synergy effects and economies of scale effects. Effects that we could have in case we stop the siloed approaches of STPs by following a more holistic concept of a Smart Sustainable City, covering also a continuous flow of innovation into the city, without necessarily always depend on large corporate SSC solutions. We try to argue that every SSC should integrate SP/STP concepts or better their features and services into their methodology. The very limited interconnectivity between these concepts within the governance models limits opportunities and performance in both systems. Redesigning the architecture of the governance models and accepting that we have to design a system-of-systems would support the possible technology flow for smart city technologies, it could support testbed functionalities and the public-private partnership approach with embedded business models. The challenge is of course in complex governance and integration, as we often face siloed approaches. But real SSC are smart as they are connecting all those unconnected siloes of stakeholders and technologies that are not yet interoperable. We should not necessarily follow anymore old greenfield approaches neither in SSCs nor in SP and STP concepts from the '80s that don't fit anymore, being replaced by holistic sustainability concepts that we have to implement in any new or revised SSC concepts. There are new demands for each SP/STP being in or close to an SC/SCC as they have a continuous demand for feeding the technology base and the application layer and should also act as testbeds. In our understanding, a big part of STP inputs and outputs are still needed, but in a revised and extended format. We know that most of the SC/STP studies claim the impact is still far from understood and often debated, therefore we must transform the concepts where SC/STPs are not own 'cities', but where they act as technology source and testbed for industry and new SSC business models, being part of the SC/STP concept and governance from the beginning.

MIMIC 94 GHz high isolation single balanced cascode mixer (94 GHz 대역의 높은 격리 특성의 MIMIC single balanced cascode 믹서)

  • Lee, Sang-Jin;An, Dan;Lee, Mun-Kyo;Moon, Sung-Woon;Bang, Suk-Ho;Baek, Tae-Jong;Kwon, Hyuk-Ja;Jun, Byoung-Chul;Yoon, Jin-Seob;Rhee, Jin-Koo
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.9
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    • pp.25-33
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    • 2007
  • In this paper, the high isolation and wideband 94 GHz MIMIC(Millimeter-wave Monolithic Integrated Circuit) single balanced cascode mixer was designed and fabricated. Also, we designed and fabricated a 3 dB tandem coupler which has a high isolation and wideband characteristic. The single balanced resistive mixer which does not require an external IF balun was designed using the 0.1 μm InGaAs/InAlAs/GaAs metamorphic HEMT(High Electron Mobility Transistor). The DC characteristics of MHEMT's are 665 mA/mm of drain current density, 691 mS/mm of maximum transconductance. The current gain cut-off frequency(fT) is 189 GHz and the maximum oscillation frequency(fmax) is 334 GHz. A 94 GHz single balanced cascode mixer was fabricated using our 0.1 μm MHEMT MIMIC process. From the measurements, the fabricated couplers showed wideband characteristics. The conversion loss of single balanced cascode mixer was 9.8 dB at an LO power of 10.9 dBm. The LO to RF isolation of single balanced cascode mixer was 29.5 dB at 94 GHz. We obtained in this study a higher LO-RF isolation compared to some other single balanced mixers.

Research on Environmental Design Implementation in Taiwan's Manufacturers Certified by ISO 14001

  • Chung, Yi-Chan;Tsai, Chih-Hung
    • International Journal of Quality Innovation
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    • v.7 no.1
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    • pp.177-194
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    • 2006
  • This research investigates the status of environmental design implementation in Taiwan's industries (Certified by ISO 14001) by employing questionnaire survey. The correlation between the degree of environmental design implementation in Taiwan's industries and the relevant entrepreneurial characteristics are examined. Twenty-six environmental design principles in four phases: design, manufacturing, sales and transportation, and disposal are used to define and assess the current status of environmental design. The data analysis methods applied to this research includes descriptive statistics, T-test, Chi-square test, and single-factor analysis of variance (ANOVA). It is evident that 21 out of the 26 environmental design principles are frequently and consistently employed by the manufacturers in Taiwan. The results indicate that environmental design implementation is becoming mature in Taiwan's industries.

A Study on the Direction of Reform in Licensing Policy of Government R&D Outputs to Promote Academic Technology Transfer (대학의 기술이전 촉진을 위한 국가 연구개발사업의 기술료제도 개선방안)

  • Song, Choong-Han;Kim, Hae-Do
    • Journal of Korea Technology Innovation Society
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    • v.11 no.1
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    • pp.1-22
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    • 2008
  • The Korean government has tried to increase the total national R&D investment and, to streamline acts and regulations concerning national R&D activities. Korea's total R&D expenditure in the field of S&T for the year 2006 amounted to about 27.3 trillion won including government R&D of 8.9trillion won. The Korean government enacted several pieces of legislation concerning S&T: the "Technology Transfer Promotion Act (1999)" ; the "Framework Act on Science and Technology (2000)", and the "Presidential Regulation for Managing the Government R&D Programs (2001)." With these efforts the capacity of Korea S&T has made great strides recently. But for years Korea has run a severe deficit of technology trade. The Korea's balance ratio of technology trade is 0.36 (export/import). It means that Korean industry excessively depends on foreign resource in introducing new technologies. The Korean government has put a lot of effort into promoting the commercialization of technologies developed in universities. The public technology transfer policy of the government has improved the infrastructure of technology transfer and commercialization. However, the government has realized that these policies have not been as effective as they were anticipated. In spite of these various efforts, the technologies obtained from the government R&D Programs have not been transferred to the Korean industry properly. Only 13.6% of technologies developed in universities for the year 2005 were transferred to industry. The academic royalty revenues for the year was 0.15% of their total R&D expenditure It shows only a twentieth of the percentage of royalty revenues for the American universities. The reasons of poor commercialization of academic technologies are intermingled with imperfection of technology transfer system, lack of licensing experience, immaturity of socio-economic circumstance and inadequacy of legal system and government policy. In this study we analyzed the problems of legal system and policy in licensing of government R&D outputs and suggested proper alternatives.

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Improvement Directions of Regional Science and Technology Policies in the Context of Creative Economy Paradigm: the case of Daegu and Gyungbuk regions (창조경제 패러다임에서의 지방과학기술정책의 개선방향: 대구.경북의 사례를 중심으로)

  • Kim, Taewoon
    • Journal of the Economic Geographical Society of Korea
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    • v.17 no.1
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    • pp.45-68
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    • 2014
  • This research addressed improvement directions and problems of regional science and technology(S&T) policies in Daegu and Gyungbuk regions in terms of 'Creative Economy' which was a new paradigm of Park Gunhye Government. Creative Economy stressed the construction of an ecosystem in regional research and development activities, and thus it was deeply associated with building a regional innovation system(RIS). There were several problems to strengthen RIS with regional S&T policies of the regions as follows: limits in meeting regional needs due to excessive attraction of central government's projects into regions; the high ratio of programs for future basic research potentials; the lack of programs assessing and coordinating the policies; and the lack of experiences and expenditure of research institutes and firm supporting organizations. Due to these problems, the role of the policies in building RIS did not seem to be effective. Therefore, the policies need to be improved through the following measures: the expansion of regional own policies focusing regional needs; the enhancement of policy coordination by shifting to systematic approach; the expansion of soft supporting programs for constructing innovation systems; and the enhancement of stability and ability of research institutes and firm supporting organizations.

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Estimation of S&T Knowledge Production Function Using Principal Component Regression Model (주성분 회귀모형을 이용한 과학기술 지식생산함수 추정)

  • Park, Su-Dong;Sung, Oong-Hyun
    • Journal of Korea Technology Innovation Society
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    • v.13 no.2
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    • pp.231-251
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    • 2010
  • The numbers of SCI paper or patent in science and technology are expected to be related with the number of researcher and knowledge stock (R&D stock, paper stock, patent stock). The results of the regression model showed that severe multicollinearity existed and errors were made in the estimation and testing of regression coefficients. To solve the problem of multicollinearity and estimate the effect of the independent variable properly, principal component regression model were applied for three cases with S&T knowledge production. The estimated principal component regression function was transformed into original independent variables to interpret properly its effect. The analysis indicated that the principal component regression model was useful to estimate the effect of the highly correlate production factors and showed that the number of researcher, R&D stock, paper or patent stock had all positive effect on the production of paper or patent.

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Personalized Diabetes Risk Assessment Through Multifaceted Analysis (PD- RAMA): A Novel Machine Learning Approach to Early Detection and Management of Type 2 Diabetes

  • Gharbi Alshammari
    • International Journal of Computer Science & Network Security
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    • v.23 no.8
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    • pp.17-25
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    • 2023
  • The alarming global prevalence of Type 2 Diabetes Mellitus (T2DM) has catalyzed an urgent need for robust, early diagnostic methodologies. This study unveils a pioneering approach to predicting T2DM, employing the Extreme Gradient Boosting (XGBoost) algorithm, renowned for its predictive accuracy and computational efficiency. The investigation harnesses a meticulously curated dataset of 4303 samples, extracted from a comprehensive Chinese research study, scrupulously aligned with the World Health Organization's indicators and standards. The dataset encapsulates a multifaceted spectrum of clinical, demographic, and lifestyle attributes. Through an intricate process of hyperparameter optimization, the XGBoost model exhibited an unparalleled best score, elucidating a distinctive combination of parameters such as a learning rate of 0.1, max depth of 3, 150 estimators, and specific colsample strategies. The model's validation accuracy of 0.957, coupled with a sensitivity of 0.9898 and specificity of 0.8897, underlines its robustness in classifying T2DM. A detailed analysis of the confusion matrix further substantiated the model's diagnostic prowess, with an F1-score of 0.9308, illustrating its balanced performance in true positive and negative classifications. The precision and recall metrics provided nuanced insights into the model's ability to minimize false predictions, thereby enhancing its clinical applicability. The research findings not only underline the remarkable efficacy of XGBoost in T2DM prediction but also contribute to the burgeoning field of machine learning applications in personalized healthcare. By elucidating a novel paradigm that accentuates the synergistic integration of multifaceted clinical parameters, this study fosters a promising avenue for precise early detection, risk stratification, and patient-centric intervention in diabetes care. The research serves as a beacon, inspiring further exploration and innovation in leveraging advanced analytical techniques for transformative impacts on predictive diagnostics and chronic disease management.