• Title/Summary/Keyword: Inner behavior

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The Mouse Mutations Circling and Spinner are Allelic

  • Kyoung in Cho;Lee, Eun-Ju;Kim, Myoung-Ok;Kim, Sung-Hyun;Pakr, Jun-Hong;Jung, Boo-Kyung;Kim, Hee-Chul;Sol ha Hwang;Suh, Jun-Gyo
    • Proceedings of the KSAR Conference
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    • 2003.06a
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    • pp.90-90
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    • 2003
  • Circling mice were recorded to display profound deafness and a head-tossing and bidirectional circling behavior, showing an autosomal recessive mode of inheritance. In addition, the histological examination of inner ears revealed that the region around organ of Corti, spiral ganglion neurons and outer hair cells showed definite abnormality. On the other hand, a genetic linkage map was constructed in an intraspecific backcross between cir and C57BL/6J mice. The cir gene was mapped to a region between D9Mitl16/D9Mit15 and D9Mit38 on the mouse chromosome 9. Estimated distances between cir and D9Mitl16, and between cir and D9Mit38 are 0.70 $\pm$ 0.40 and 0.23 $\pm$ 0.23 cM, respectively. The markers in order was defined as follows: centromere-D9Mit182- D9Mit51/ D9Mit79/ D9Mit310- D9Mit212/ D9Mit184- D9Mit116/ D9Mit15- cir- D9Mit38- D9Mit20- D9Mit243- D9Mit16- D9Mit55/ D9Mit125- D9Mit281 Based on genetic mapping, we constructed for a YAC contig across cir region. They covered the entire region or cir and cir gene was located on between the lactotransferrin (ltf) and the macrotubule-associated protein (map4). It is known that sr gene is localized in 64cM of mouse chromosome 9. The two mouse were found to be allelic by complementation test. Recently the spinner mouse has been mapped to our cir region, and tmie gene were elucidated. And further study will be needed in circling mouse to prove tmie gene mutaiton.

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Alexithymia and Pressure Pain Threshold in Patients with Somatoform Disorder who have Pain (동통을 가진 신체형장애 환자에서 감정표현능력과 압통역치)

  • Song, Ji-Young;Kim, Tae-Soo;Oh, Dong-Jae;Yoon, Doh-Joon;Yum, Tae-Ho
    • Korean Journal of Psychosomatic Medicine
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    • v.2 no.1
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    • pp.69-79
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    • 1994
  • The authors investigated the relationship between the response to the external stimulation and ability of verbal behavior in the patients with somatoform disorder who have pain. The subjects consisted of 34 patients(male 10, female 24) and 37 normal controls(male 19, female 18). Pressure pain thesholds were measured by algometer and alexithymia was assessed by Toronto Alexithymia Scale(TAS). Somatization Scale of SCL-90R and Parental Bonding Instrument were also used. It was shown that 82.4% of the patients had chronic somatic complaints. The mean values of TAS, degree of somatic symptoms and pressure pain thresholds were significantly higher in the patient group than in the normal controls. 44.1% of the patients was considered alexithymia group and there was no correlation between scores of alexithymia and value of pressure pain thresholds. In conclusion, the patients with somatoform disorder who had pain were dull in pain perception to external physical stimulation. This result suggested that their low perception of pain could be closely related with chronicity of illness. And the Poverty of verbal expression of inner emotion was suggested to be one of the factors affecting somatization and difficulty in psychotherapy.

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Implementation of Massive FDTD Simulation Computing Model Based on MPI Cluster for Semi-conductor Process (반도체 검증을 위한 MPI 기반 클러스터에서의 대용량 FDTD 시뮬레이션 연산환경 구축)

  • Lee, Seung-Il;Kim, Yeon-Il;Lee, Sang-Gil;Lee, Cheol-Hoon
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.21-28
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    • 2015
  • In the semi-conductor process, a simulation process is performed to detect defects by analyzing the behavior of the impurity through the physical quantity calculation of the inner element. In order to perform the simulation, Finite-Difference Time-Domain(FDTD) algorithm is used. The improvement of semiconductor which is composed of nanoscale elements, the size of simulation is getting bigger. Problems that a processor such as CPU or GPU cannot perform the simulation due to the massive size of matrix or a computer consist of multiple processors cannot handle a massive FDTD may come up. For those problems, studies are performed with parallel/distributed computing. However, in the past, only single type of processor was used. In GPU's case, it performs fast, but at the same time, it has limited memory. On the other hand, in CPU, it performs slower than that of GPU. To solve the problem, we implemented a computing model that can handle any FDTD simulation regardless of size on the cluster which consist of heterogeneous processors. We tested the simulation on processors using MPI libraries which is based on 'point to point' communication and verified that it operates correctly regardless of the number of node and type. Also, we analyzed the performance by measuring the total execution time and specific time for the simulation on each test.

Paclitaxel Coating on ePTFE Artificial Graft and the Release Behavior (ePTFE 인공혈관에 대한 파클리탁셀의 코팅 및 방출거동)

  • Lim, Soon-Yong;Kim, Cheol-Joo;Kim, Eun-Jin;Kwon, Oh-Kyoung;Kwon, Oh-Hyeong
    • Polymer(Korea)
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    • v.36 no.3
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    • pp.326-331
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    • 2012
  • In this study, expanded poly(tetrafluoro ethylene) (ePTFE) graft was modified to be used as a hemodialysis vascular access. Biodegradable poly(D,L-lactide-$co$-glycolide) (PLGA) was coated onto the inner surface of ePTFE graft with paclitaxel, which is often used as an anti-cancer agent and for reducing neointimal hyperplasia. Surface characterization before and after PLGA coating was carried out by SEM and ATR-FTIR. Porous sturcture of ePTFE was maintained after coating of PLGA solution. The amounts of coated PLGA and paclitaxel determined by ATR-FTIR and HPLC were 1.96 and 0.263 mg/$cm^2$, respectively. Young's modulus was decreased and tensile strength was increased by PLGA coating. Released paclitaxel as a function of incubation time was monitored by HPLC. Approximately 35% of coated paclitaxel was released steadily for 4 weeks with the biodegradation of PLGA. From these results, it is expected that the effect of paclitaxel on reducing neointimal hyperplasia and stenosis is maintained for a long time.

Dynamic Behavior of Large Diameter steel Pipe Piles during driving (대구경 강관말뚝의 항타시 동적 거동)

  • 이영남;이종섭
    • Journal of the Korean Geotechnical Society
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    • v.16 no.4
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    • pp.141-148
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    • 2000
  • For the construction of 4.8km long Multi-Purpose Jamuna Bridge in Bangladesh, 2 or 3 large diameter open-ended steel pipe piles were used for the foundation of piers. A total of 123 piles were driven for 50 piers and 2 test piles from the river bed through the normally-consolidated upper sand layer and rested n top of gravel layer. Two types of piles, having 3.15 or 2.50m diameter and variable wall thickness in the range of 40 to 60mm, were driven to the depths of 69 to 74m with the rake of 6:1 by connecting 2 or 3 pieces of short piles. Dynamic pile tests were performed on 24 selected piles during pile driving and soil plug length inside the pile was also measured after driving of each short section.These piles were plugged with soil to, though slightly affected by pile diameters, about 75% of total length of pile driven. Active plug at the tip of pile contributed substantial amount of inner skin friction to the total capacity. Piles soon after driving showed a skin-friction dominant pile behaviour, tat is, 90% of total capacity being developed by skin resistance. Quakes values and Smith damping factors were almost constant regardless of pile diameters. This result reflects the influence of uniform soil condition at the site.

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Compressive Properties of Ultra High Strength Concrete Exposed to High Temperature (고온에 노출된 초고강도 콘크리트의 압축특성)

  • Kang, Yong-Hak;Kang, Choong-Hyun;Choi, Hyun-Guk;Shin, Hyun-Jun;Kim, Wha-Jung
    • Journal of the Korea Concrete Institute
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    • v.26 no.3
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    • pp.377-384
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    • 2014
  • Recently, the trend toward larger architectural structures continues and accelerates demand for Ultra High Strength Concrete (UHSC) which satisfies structural performance. However, UHSC has weakness in fire and the performance tests are required. In this paper, the change of mechanical properties of 100 MPa grade UHSC exposed to high temperatures ($20^{\circ}C{\sim}800^{\circ}C$) was observed to develop high temperature material model of UHSC: residual compressive strength, modulus of elasticity, property of stress-strain on monotonous loading and property of stress-strain on cyclic loading. In addition, TG/DTA and SEM Images analyses were performed to investigate chemical and physical characteristics of UHSC, and the results of this research were compared with those of previous studies. As a result, UHSC at the heating temperature of $300^{\circ}C$ showed a sharp decrease of residual compressive strength and modulus of elasticity. And It was shown that UHSC had a plastic behavior at more than $400^{\circ}C$ on the cyclic loading and revealed a same tendency in both monotonous and cyclic loading of all heating temperatures. In addition, through TG/DTA and SEM images analyses compared with those from previous studies, it was shown that the deterioration of concrete inner tissue, water evaporation and chemical reaction caused the decrease of residual compressive strength and modulus of elasticity.

A Study on the Androgynous Expressed in Contemporary Fashion (현대 패션에 나타난 앤드로지너스에 관한 연구)

  • 김경옥;금기숙
    • Journal of the Korean Society of Costume
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    • v.36
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    • pp.239-262
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    • 1998
  • The pursuit of freedom by the individual--desire to be liberated from all forms of restrictions-- is one of the defining character-istic of the modern society. As costume is, in part, a product of the spirit of the times, it was only natural that this desire for freedom would find its expression in modern costume as well. Among various forms of restrictions, differentiaton by sex has placed one of the most significant binding influences on individual behavior. From early times, the dichotomous division by sex was incorporated into the disign of costume, and the traditional differestriction of costume by sex imposed a significant restriction on the background,“the modern androhynous look”was born as a by-product of the sexual liberation movement in the second half of the 20th century, based on the concept of the individual as a complete human being rather than as a member exclusively of either the male or the female sex. This paper seeks to examine the androgynous look within a coherent theoretical frame-work, and explore new design possibilities by analyzing and understanding the visual characteristics of the androgynous look. In addition, this paper seeks to define the functional aspects of the androgynous look based on the premise that costume is an embodiment of the spirit of the times. As for research methodology, both theoretical and historical methods are employed. Through a theoretical examination of historical documents, the meaning of the androgynous look is explored from various angles, and order to examine its place in modern fashion, an-drogynous styles are categorized and system atically analyzed. The main findings of the paper can be summarized as follows : 1. Androgyny is a compound word consisting of“andro-”(meaning man) and“gyn-”(meaning woman). In modern times, this word has been associated with the socio-cultural aspect of gender rather than the physical or physiological aspect with the pshchological characteristics of the male and female sexes. Androgynous styles also appear in fashion and general arts such as drama, film, dance, and music. In fashion, the androgynous look, represented by the visual superimposition of “masculine”and “faminine”elements, has emerged as a major element of the 20th-century costume, and has gained broad acceptance among those free spirits wishing to be liberated from the conventional conceptions of male clothing, and the unisex look. 3. The androgynous look in modern fashion reflects the spirit of the 20th century society and culture, and performs various functions as follows : expression of fun, change in gender roles, expression of the inner consciousness, and pursuit of the ideal human type.

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Multistable Microactuators Functioning on the Basis of Electromagnetic Lorentz Force: Nonlinear Structural and Electrothermal Analyses (전자기 로렌츠력을 이용한 다중안정성 마이크로 액추에이터의 비선형 구조 및 전기-열 해석)

  • Han, Jeong-Sam
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.8
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    • pp.1119-1127
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    • 2010
  • In this paper, the design and nonlinear simulation of a multistable electromagnetic microactuator, which provides four stable equilibrium positions within its operating range, have been discussed. Quadstable actuator motion has been made possible by using both X- and Y-directional bistable structures with snapping curved beams. Two pairs of the curved beams are attached to an inner frame in both X- and Y-directions to realize independent bistable behavior in each direction. For the actuation of the actuator at the micrometer scale, an electromagnetic actuation method in which Lorentz force is taken into consideration was used. By using this method, micrometer-stroke quadstability in a plane parallel to a substrate was possible. The feasibility of designing an actuator that can realize quadstable motion by using the electromagnetic actuation method has been thoroughly clarified by performing nonlinear static and dynamic analyses and electrothermal coupled-field analysis of the multistable microactuator.

The Effects of Service Qualities on Customer Satisfaction and Behavioral Intention in Coffee Shops (커피전문점의 서비스품질이 고객만족과 행동의도에 미치는 영향)

  • Kim, Ho-Sik;Shim, Jae-Hyun
    • The Journal of Industrial Distribution & Business
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    • v.8 no.5
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    • pp.95-109
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    • 2017
  • Purpose - The purpose of this study is to classify the quality factors of coffee shop customers with the service quality based on the SERVQUAL, selection attributes, and service qualities used in previous studies. The path structure of coffee shops' quality factors → customer satisfaction → trust → behavioral intention was analyzed in order to confirm the system of coffee shops' quality factors. Research design, data, and methodology - The survey of was conducted with college students of Kangwon University. A total of 250 questionnaires were distributed, with 232 collected. Of them, Excluding 36 respondents' because of incomplete answers and missing values, 196 responses were used in the final analysis. Empirical analysis was made through factor analysis, correlation analysis, multiple regression analysis, simple regression analysis and mediating regression analysis by using Statistics Package SPSS 19.0. Results - The results are as follows: Firstly, coffee shops' quality factors were classified into seven categories like service encounter quality, product quality, cleanliness, overall interior, purchase quality, convenience, and aesthetics. Secondly, service encounter quality, product quality, purchase quality, and aesthetics had a positive effect on customer satisfaction, respectively. Thirdly, it showed that service encounter quality, product quality, overall interior, purchase quality, and aesthetics had a positive effect on trust, respectively. Fourthly, customer satisfaction had a positive effect on behavioral intention. Lastly, after verifying the effect relations of trust between customer satisfaction about coffee shop and behavioral intention, customer satisfaction has a positive effect on trust and trust has a positive effect on behavioral intention. On the other hand, trust did not have a mediating effect between customer satisfaction and behavioral intention. But, cleanliness, convenience, and overall interior did not have a positive effect on customer satisfaction. Conclusions - Coffee shop consumers put importance on price, discount systems, taste, and freshness, but more on courteous and kind services of coffee shop staff or comfortable and calming atmosphere of inner space. Thereby, coffee shop marketers need to take factors like service encounter quality and aesthetics into more consideration. In addition, customer satisfaction has an effect on trust, while trust on behavioral intention, even though trust is not mediated between customer satisfaction and behavior intention.

Experimental Verification of Implantable Middle Ear System using the Differential Electromagnetic Type Transducer (차동 전자 트랜스듀서를 이용한 이식형 인공중이 시스템의 실험적 검증)

  • 송병섭;이기찬;원철호;박세광;이상흔;조진호
    • Journal of Biomedical Engineering Research
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    • v.23 no.3
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    • pp.217-225
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    • 2002
  • The implantable middle ear(IME) system, which has good sound quality. superior sound intelligibility and wide frequency characteristics. can resolve the sound distortion and ringing effect by sound feedback at high gain operation those are the major problems of conventional hearing aid. In this paper, we have manufactured the IME system using differential electromagnetic transducer(DET) and verified the performance of the system by carrying out vibration and animal implanting experiment. The DET was manufactured using micro-machining technology and vibration experiment of the transducer was performed to inspect whether the transducer could vibrate in accordance with the applied sound signal or not. And the result of the loaded experiment using temporal bone sampled from cadaver showed that the transducer can drive the middle ear bone and transmit the signal to inner ear After the internal unit of IME system was implanted in a dog. the auditory brainstem response (ABR) test was carried out. The result of the test indicated the Proper behavior of the IME system in the living body From the results of the experiments, it is verified that the manufactured system ewll work well when it is applied to human and a basis of clinical experiment of IME system to real human hearing impaired was be arranged.