• 제목/요약/키워드: Inner Production

검색결과 509건 처리시간 0.024초

Effects of maternal undernutrition during late pregnancy on the regulatory factors involved in growth and development in ovine fetal perirenal brown adipose tissue

  • Yang, Huan;Ma, Chi;Zi, Yang;Zhang, Min;Liu, Yingchun;Wu, Kaifeng;Gao, Feng
    • Animal Bioscience
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    • 제35권7호
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    • pp.1010-1020
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    • 2022
  • Objective: The experiment was conducted to evaluate the effects of maternal undernutrition during late pregnancy on the expressions of genes involved in growth and development in ovine fetal perirenal brown adipose tissue (BAT). Methods: Eighteen ewes with singleton fetuses were allocated to three groups at day 90 of pregnancy: restricted group 1 (RG1, 0.33 MJ metabolisable energy [ME]/kg body weight [BW]0.75/d, n = 6), restricted group 2 (RG2, 0.18 MJ ME/kg BW0.75/d, n = 6), and a control group (CG, ad libitum, 0.67 MJ ME/kg BW0.75/d, n = 6). The fetuses were removed at day 140 of pregnancy. All data were analyzed by using the analysis of variance procedure. Results: The perirenal fat weight (p = 0.0077) and perirenal fat growth rate (p = 0.0074) were reduced in RG2 compared to CG. In fetal perirenal BAT, the protein level of uncoupling protein 1 (UCP1) (p = 0.0001) was lower in RG1 and RG2 compared with CG and UCP1 mRNA expression (p = 0.0265) was decreased in RG2. The protein level of myogenic factor 5 (Myf5) was also decreased in RG2 (p = 0.0001). In addition, mRNA expressions of CyclinA (p = 0.0109), CyclinB (p = 0.0019), CyclinD (p = 0.0015), cyclin-dependent kinase 1 (CDK1) (p = 0.0001), E2F transcription factor 1 (E2F1) (p = 0.0323), E2F4 (p = 0.0101), and E2F5 (p = 0.0018) were lower in RG1 and RG2. There were decreased protein expression of peroxisome proliferator-activated receptor-γ (PPARγ) (p = 0.0043) and mRNA expression of CCAAT/enhancer-binding protein-α (C/EBPα) (p = 0.0307) in RG2 and decreased PPARγ mRNA expression (p = 0.0008) and C/EBPα protein expression (p = 0.0015) in both RG2 and RG1. Furthermore, mRNA expression of bone morphogenetic protein 4 (BMP4) (p = 0.0083) and BMP7 (p = 0.0330) decreased in RG2 and peroxisome proliferator-activated receptor co-activator-1α (PGC-1α) reduced in RG2 and RG1. Conclusion: Our observations support that repression of regulatory factors promoting differentiation and development results in the inhibition of BAT maturation in fetal perirenal fat during late pregnancy with maternal undernutrition.

유동안정성과 생산량을 고려한 2단 생산튜빙 디자인 (Tapered production tubing design considering flow stability and production rate)

  • 김성일;조경남;최종근
    • Journal of Advanced Marine Engineering and Technology
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    • 제37권5호
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    • pp.548-556
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    • 2013
  • 생산량 증대를 위한 방법으로 다른 두 내경의 2단 튜빙을 이용한 기법이 제안되고 있다. 본 연구에서는 다양한 2단 튜빙조합을 고려하여 각 목적에 부합하는 조합들을 제시하였다. 기존연구에서 고려한 생산량뿐만 아니라 유동안정성을 확보하는 결과를 제시하였다. 유동안정성은 tubing pressure traverse, 액체부피비, 운영조건의 안정성을 통해 분석되었다. 본 연구에서 분석한 가상유전의 경우 순현재가치가 가장 큰 2단 튜빙은 하단이 4.5 in 내경에 길이가 2000 ft이며 상단은 5.5 in 내경에 길이가 8000 ft인 조합이다. 2단 튜빙간 마찰압력손실 차이는 크지 않았기 때문에 단일튜빙과 비교했을 때보다 다양한 조합이 가능하였다. 튜빙하단에선 liquid loading을 방지하기 위해 작은 액체부피비를 유지하는 것이 중요한데, 이는 2단 튜빙 하단에서 작은 내경을 사용함으로써 가능하였다. 생산운영의 분석결과로부터 다양한 튜빙 디자인이 가능함을 확인하였다.

내통의 플래시 및 충진불량에 대한 해결방법에 관한 연구 (A study on the flashes and filling defects of inner part and on problem-solving measures)

  • 김세환;최계광;이춘규
    • Design & Manufacturing
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    • 제6권2호
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    • pp.79-83
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    • 2012
  • Inner part is used as an insulator in wire fuses. After injection molding, inner part has been showed flashes, filling defects and deformation. After production, operators have to cut off flashes, one by one. this process leads to continuous low productivity and loss of source materials. This study focuses on identifying the causes for flashes, filling defects, clamping force of injectors, mold adhesion, resin of liquidity and others, and on resolving those issues.

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밤 박피 시스템 개발 (Development of Chestnut Peeling System)

  • 김종훈;박재복;최창현
    • Journal of Biosystems Engineering
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    • 제22권3호
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    • pp.289-294
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    • 1997
  • The chestnut is a well-known and important forest product in Korea. The annual production of chestnut is about 100, 000tons and its cultivating area is 80, 000ha. However, the peeling process of outer and inner skins of chestnut is very difficult due to hardness and adhesiveness of chestnut skin. The peeling process of chestnut was operated by manual work and the performance of chestnut peeling machine is very low. The purpose of this study is to develope the prototype of new chestnut peeling system. The hardness of chestnuts was tested with six different drying conditions and its range was from 949$g/mm^2$ to 2, 149$g/mm^2$. The hardness of chestnuts was decresed gradually during the drying process. The chestnut peeling Process includes sorting, storage, drying, outer skin cutting, flame peeling, continuous frictional skin peeling, and inner skin cutting operation. The developed chestnut peeling system consists of outer skin cutter, flame peeler, continuous frictional skin peeler and inner skin cutter. The system can peel domestic chestnuts at 150$kg/hr$ with peeling rate of 78%.

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공압 매니퓰레이터의 강인 힘제어 (Robust Force Control of Pneumatic Manipulator)

  • 박정규;노리츠구토시로
    • 대한기계학회논문집A
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    • 제20권2호
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    • pp.540-552
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    • 1996
  • In this paper, a compensation method of disturbance using a disturbance observer is proposed for a force control of a pneumatic robot manipulator. The generated torque by a pneumatic actuator can be estimated based on the pressure signals. The inner torque control system is constructed by feeding back the generated torque to improve the dynamic characteristics of the actuator. In order to reduce the influence of disturbances comprising friction torque, parameter variations of plant and environment and so on, the reaction torque control system is constructed with a disturbance observer which estimates the disturbances based on the reference input to the inner torque control system and the reaction torque sensed with a forced sensor. From some simulations and experiments, it is confirmed that the proposed control system is effective to improve the robustness for the friction torque and the parameter change of object in the force control of a pneumatic robot manupulator.

유체동압 메카니즘을 이용한 고RPM용 소결함유베어링의 개발 (Development of Sintered Oilless Bearing using Fluid-Dynamic Mechanism For High-RPM Application)

  • 최윤철
    • 한국분말재료학회지
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    • 제4권4호
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    • pp.275-282
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    • 1997
  • Sintered oilless bearing using fluid-dynamic mechanism for high revolution of over 10,000 rpm was developed by Powder metallurgy Process. Developed bearing was composed of Fe-40-60%Cu of which inner face consisted of six-regular-prominence-and-depression. Inner face has controlled pore size and amount according to application. Jitter and friction properties were tested under assembled conditions with housing and motor. Bearing-own properties and precision were also tested because of demanding for assembled properties. Measurement-skill as well as mould-production-skill were investigated for the precision of bearing. Final precision reached 2 ${\mu}m$ in inner diameter tolerance and 5 ${\mu}m$ in coaxiality under assembled conditions.

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냉연신 공법을 이용한 압력용기의 제조에 관한 연구 (A Study on Pressure Vessel using Cold Stretch Method)

  • 한규택
    • 한국기계가공학회지
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    • 제17권1호
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    • pp.153-160
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    • 2018
  • A pressure vessel consists of an inner tank and the outer tank; the material of the inner tank is austenite stainless steel, and the outer tank is general carbon steel. As the storage amount increase, the size of the inner tank for LNG also increases, which eventually increases the weight of the LNG storage tank. The Cold Stretch method can transport and store the LNG in a larger amount than the conventional pressure container, and the weight of the pressure vessel can also be reduced at 50 70% due to the reduction of the thickness, which is excellent from an economic and energy consumption perspective. Although the Cold Stretch method has these advantages, the domestic situation has not developed any related legislation. In this study, the actual production of pressure vessels using the Cold Stretch method will be processed and the volume expansion after the Cold Stretch will be checked and compared with the mechanical properties.

벡터내적 기반 카메라 외부 파라메터 응용: 카메라와 레이져스캐너간의 캘리브레이션 (Camera Exterior Parameters Based on Vector Inner Product Application: Exterior Calibration of a Camera and a Range Finder)

  • 전재춘
    • 대한원격탐사학회지
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    • 제23권6호
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    • pp.553-558
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    • 2007
  • 영상의 두점과 카메라 초점을 지나는 벡터들간의 사잇각을 기반한 방정식은 카메라 위치와 제세가 독립적으로 분리시킬 수 있다. 본 논문은 이 방정식의 두번째 응용으로써, 벡터내적 기반 방정식에 의해 생성된 곡면 분석을 통한 카메라와 레이져 라인 스캐너간의 상대적인 외부표정 계산을 소개한다.

Effect of Dietary Structural to Nonstructural Carbohydrate Ratio on Rumen Degradability and Digestibility of Fiber Fractions of Wheat Straw in Sheep

  • Tan, Z.-L.;Lu, D.-X.;Hu, M.;Niu, W.-Y.;Han, C.-Y.;Ren, X.-P.;Na, R.;Lin, S.-L.
    • Asian-Australasian Journal of Animal Sciences
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    • 제15권11호
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    • pp.1591-1598
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    • 2002
  • The effect of different dietary structural carbohydrate (SC) to nonstructural carbohydrate (NSC) ratios on fiber degradation, digestion, flow, apparent digestibility and rumen fluid characteristics was studied with a design using 18 wethers fitted with permanent rumen and duodenum cannulae. All sheep were divided into six groups randomly, receiving six diets with varying SC to NSC ratios. All diets contained the same proportion of wheat straw and concentrate. The dietary SC to NSC ratios were adjusted by adding cornstarch to the concentrate supplements. The duodenal and fecal flows of dry matter (DM), neutral detergent fiber (NDF), acid detergent fiber (ADF), hemicellulose (HC) and cellulose (CEL) were estimated using chromium-mordanted wheat straw as a flow marker. The degradation parameters of wheat straw DM, NDF, ADF, HC and CEL were determined by incubating the ground wheat straw in nylon bags in the rumen for different periods of time. There was no effect (p>0.05) of the different dietary SC to NSC ratios on rumen pH or $NH_3$-N, but acetate, propionate and butyrate concentrations were significantly affected (p<0.05 or p<0.01) by dietary SC to NSC ratios in the rumen fluid. When the dietary SC to NSC ratio was 2.86, the highest rumen degradability of wheat straw DM, NDF, ADF and CEL was found, but the highest apparent rumen digestibilities of DM, NDF, ADF, HC and CEL occurred at a 2.64 SC to NSC ratio. However, because of compensatory digestion in the hindgut, the apparent digestibilities of DM, NDF, ADF, HC and CEL were highest when the dietary SC to NSC ratio was 2.40. In conclusion, there is a optimal range of dietary SC to NSC ratios (between 2.86 and 2.40) that is beneficial to maximize wheat straw fiber degradation and apparent digestibility.

Effects of Dietary Nitrogen Sources on Fiber Digestion and Ruminal Fluid Characteristics in Sheep Fed Wheat Straw

  • Tan, Z.-L.;Lu, D.-X.;Hu, M.;Niu, W.-Y.;Han, C.-Y.;Ren, X.-P.;Na, R.;Lin, S.-L.
    • Asian-Australasian Journal of Animal Sciences
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    • 제14권10호
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    • pp.1374-1382
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    • 2001
  • Fifteen Inner Mongolian wethers with permanent ruminal and duodenal cannulas were used to study the effects of dietary rumen-undegradable protein (RUP) to rumen-degradable protein (RDP) ratios or protein sources on fiber digestion in the gastrointestinal tract and ruminal fluid characteristics. Fiber digestion and ruminal fermentation were not affected (p>0.05) by dietary RUP to RDP ratios (from 1.54 to 0.72). Soybean meal supplementation improved ruminal digestion. Fish meal supplementation increased (p<0.05) the ruminal degradability of fiber. The different RUP to RDP ratios (from 1.54 to 0.72) did not influence (p>0.05) ruminal fluid pH, but there were differences (p<0.05) in ruminal fluid $NH_3-N$ concentration because of urea replacement. Soybean meal as a dietary protein source decreased (p<0.05) ruminal fluid pH and increased (p<0.05 or p<0.01) $NH_3-N$, acetate, propionate and butyrate concentrations in the rumen. Fish meal as a dietary protein source decreased (p<0.05 or p<0.01) ruminal $NH_3-N$ and acetate concentrations and increased (p<0.05) ruminal propionate concentration. It can be concluded that dietary protein sources have more significant effect on fiber digestion and ruminal fermentation than different dietary RUP to RDP ratios, when the dietary crude protein requirements of growing sheep are satisfied.