• Journal of Trauma and Injury
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• 제31권3호
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• pp.117-124
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• 2018

Purpose: This study was to analyze clinical and epidemiological characteristics of elderly patients who were admitted to the emergency department (ED) due to falls by separating male and female. Methods: We retrospectively analyzed the fall patients aged 65 years or older from the data of the in-depth surveillance study of injured patients visit to the ED under the supervision of the Korea Centers for Disease Control and Prevention (KCDC) from 2011 to 2016 by separating male and female. Results: A total of 361,588 elderly fall patients were analyzed and, among them, 14,429 (37.3%) were males and 24,208 (62.7%) were females. Male and female showed similar frequency of damage happening season. However, they showed falling accident mostly on winter. The time of injury occurrence is mostly from 12:00 to 18:00 with 4,949 (34.3%) male and 8,564 (35.4%) female. Most falls occurred in daily activities, accounting for 7,614 (52.8%) in males and 14,957 (61.8%) in females, respectively. Unintentional damage accounted for the most part and 7,395 (51.2%) of male and 15,343 (63.4%) of female were injured indoors. Head and neck were the most common site of injuring, with 8,392 (58.2%) in males and 7,851 (32.4%) in females. According to ED examination outcomes, most of the patients were discharged, while the majority of the hospitalized patients were admitted to the general patient room. Conclusions: The elderly falls occurred mostly from 12:00 to 18:00, during winter and to elderly women. Also, they happened unintentionally indoors in everyday life, mostly. Proved clinical, epidemiological characteristics from this research will be used as useful indicator at validity research of development of prevent program of falling accident for elderly people.

• Journal of Trauma and Injury
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• 제31권3호
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• pp.159-165
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• 2018

Purpose: Spinning-induced rhabdomyolysis (SIR) has been increasing in recent years and accounts for a large proportion of exercise-induced rhabdomyolysis (EIR). The purpose of this study was to compare the clinical features between SIR and non-spinning exercise-induced rhabdomyolysis (NSIR), and to analyze each of these clinical features. Methods: A retrospective chart review was conducted on patients treated due to EIR from January 2006 to March 2018. Patients were divided into the SIR and NSIR groups, and their clinical factors, outcome, and blood chemistries were compared and analyzed. Results: Sixty-two patients were enrolled in this study, with 23 (37.1%) and 39 (62.9%) patients categorized in the SIR and NSIR groups, respectively. The SIR group were mostly women (78.3% vs. 38.5%, p=0.002), more frequent EIR occurrence in the first exercise class (60.9% vs. 15.4%, p=0.001), and had most complaints of thigh pain (91.3% vs. 43.6%, p=0.001). The SIR group had a higher incidence rate despite its shorter exercise duration (90.5% vs. 62.9%, p=0.024), longer hospital stay (6.0 [4.5-7.0] vs. 5.0 [3.5-6.0] days, p=0.080), and higher rate of peak CPK (15,000 U/L or higher) (91.3% vs. 74.4%, p=0.182) compared to the NSIR group. Conclusions: SIR occurs at a higher rate during the first exercise class in women compared to NSIR, and the incidence rate is higher in SIR than in NSIR despite its shorter exercise duration (less than 60 minutes). It is necessary to recognize these risks during spinning exercises and to perform these exercises sequentially and systematically.

• Archives of Plastic Surgery
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• 제49권1호
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• pp.61-69
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• 2022

Background Single free flaps are a commonly used reconstructive method for multiple soft tissue defects in digits. We analyzed the flap size, division timing, and degree of necrosis in cases with various types of flap division. Methods We conducted a retrospective review of the medical charts of patients who had undergone single free flap reconstruction for multiple soft tissue defects across their digits from 2011 to 2020. The flap types included were the lateral arm free flap, venous forearm free flap, thenar free flap, hypothenar free flap, anterolateral thigh free flap, medial plantar free flap, and second toe pulp free flap. Flap size, anastomosed vessels, division timing, and occurrence of flap necrosis were retrospectively investigated and then analyzed using the t-test. Results In total, 75 patients were included in the analysis. The success rate of the free flaps was 97.3%. All flaps were successfully divided after at least 17 days, with a mean of 47.17 days (range, 17-243 days) for large flaps and 42.81 days (range, 20-130 days) for the medium and small flaps (P=0.596). The mean area of flap necrosis was 2.38% in the large flaps and 2.58% in the medium and small flaps (P=0.935). Severe necrosis of the divided flap developed in two patients who had undergone flap division at week 6 and week 34. Conclusions In cases where blood flow to the flap has been stable for more than 3 weeks, flap division can be safely attempted regardless of the flap size.

• 대한화상학회지
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• 제16권2호
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• pp.99-103
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• 2013

Purpose: The biggest problem of wound healing is a possible occurrence of lesion. Especially, in the case of patients who have a skin injury around exposed body parts, if their treatment period drag on for long time, they can suffer from aftereffects and the costs can be passed on to a society. Therefore, in this research, we investigated the need to develop the effective medicine and appliances for the patients by examining which therapy methods are being applying to the skin damage and what is the advantage and limit by evaluating the patient's satisfaction level. Methods: We carried out an online and offline survey targeting medical teams in order to analyze device for wound care. A total of 125 medical teams applied to the research, and investigate the level of customer satisfaction. Results: The moist dressings are the most used method for wound healing. When it comes to the level of customer satisfaction, biological dressing product also has a high satisfaction level. However its high cost tends to limit the use. Conclusion: This research reached a conclusion that it is need to develop a low cost and high efficiency wound care product considering the fact that its high cost and low efficiency induced economic problems. Generally, it is needed to develop a product for skin regeneration based on biological technologies, not a product just for damage cure.

• 대한교통학회지
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• 제29권4호
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• pp.103-111
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• 2011

속도는 교통안전에 있어서 중요한 요소이며 교통사고와 밀접한 연관성이 있다. 국외의 속도변화와 사고위험 간 관계 관련 연구에서는 평균속도와 속도 표준편차가 증가하면 사고율도 증가한다고 제시하고 있지만, 국내 연구에서는 속도와 사고위험간의 관계 수립이 미흡한 실정이다. 따라서 본 연구에서는 루프검지기 속도자료와 고속도로 사고자료를 이용하여 속도를 이용한 고속도로 구간 사고율 예측모형을 개발하였다. 경부고속도로 2005~2009년의 5년 간 천안~양재 양방향 총 22구간에서 발생한 486건의 사고자료와 구간별 루프검지기 자료를 기초로 분석을 수행하였다. 종속변수를 사고율로 설정하고, 중앙 집중화경향을 나타내는 값과, 변동성을 나타내는 값, 연평균 일 교통량, 구간길이 등을 통해 산출한 구간정보 변수를 독립변수 후보로 설정하였다. 통계적 분석을 통해 사고율에 직접적으로 영향을 미치는 변수를 설정한 결과 중앙값, 최소값, 표준편차를 독립변수로 설정하였다. 모형수립 결과 실제 사고율과 예측 사고율간의 높은 상관도를 보였다. 본 연구에서 개발한 모형은 속도변화에 의한 교통안전 위험도 분석에 효과적으로 사용되어 다양한 교통정책 및 운영관리전략 시행에 따른 교통안전 효과분석시 유용한 도구로서 활용될 수 있을 것으로 기대된다.

• 한국균학회지
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• 제27권6호
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• pp.420-423
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• 1999

버섯재배에 피해를 주는 긴수염버섯파리의 발생양상을 알아보기 위하여, 경남 산청과 사천의 느타리버섯 재배사에서 성충과 유충 및 용의 밀도변동을 조사하였다. 긴수염버섯파리는 버섯재배 전기간 동안 유아등 및 배지에서 발견되었으며 버섯재배가 진행됨에 따라 밀도가 증가하였다. 유충의 경우 종균접종후 30일 경부터 배지에서 발생하기 시작하였다. 발생이 가장 많은 시기는 봄재배기간인 $3{\sim}6$월 하순이었고 $8{\sim}9$월 중에는 발생이 적었다. 가을재배시에 다시 밀도가 높아지며 겨울재배시에도 상당한 발생과 피해를 나타냈다. 가해양상으로는 유충이 배지와 균사를 가로지르며 섭식하고, 균사간 결합을 끊어서 균사생장과 발이가 불량하게 되고, 버섯대의 기부에서 주름살까지 파고들어 버섯형성과 상품성에 피해를 줄뿐만 아니라 배지도 직접 가해하였다.

• 식물병연구
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• 제7권1호
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• pp.37-41
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• 2001

복숭아 수확 후 보르도액의 살포효과를 구명하기 위하여 미백도 품종에 대해 9월 중순부터 1∼3회 살포한 후 이듬해 5월부터 세균성구멍병 이병율을 조사하였을 때, 보르도액 살포에 의한 방제효과는 살포횟수가 많을수록 높게 나타났다. 복숭아 수확기인 8월 상순의 경우 잎에서는 무처리구의 27.4%∼38.1%에 비해 보르도액 살포구에서는 9.7%∼31.8%의 이병율로 16.5%∼64.6%의 방제가를 보였고, 과실에서도 잎에서와 비슷한 경향이었는데 무처리구의 17.2%∼21.6%에 비해 41.9%∼70.9%의 방제가를 나타내었다. 보르도액 살포로 인한 약해는 6-6식 보르도액에서 2정도의 약해를 나타내었고, 4-12식 및 4-8식 보르도액에서는 약해가 없었으며, 복숭아 품종간에는 차이를 보이지 않은 경향이었다.

• 한국균학회지
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• 제28권1호
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• pp.49-54
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• 2000

1. 저장 중 Penicillium에 이병된 사과, 배, 귤, 포도를 TLC 및 HPLC로 주요독소들을 검정한 결과 patulin만 검출되었고, citrinin은 검출되지 않았다. patulin 독소는 사과에서 $5.68\;{\mu}46.81\;{\mu}g/g$, 배에서 $3.48{\sim}84.71\;{\mu}g/g$, 귤에서 $0.16{\sim}0.27\;{\mu}g/g$검출되었으나 포도에서는 전혀 검출되지 않았다. 2. 과실류 Penicillium 저장 중 억제효과를 검정한 결과 사과, 배, 귤에 대하여 sodium hypochloride gas처리나 열처리$(37^{\circ}C)$에 의하여 방제효과가 켰으며 특히 열처리$(37^{\circ}C)$는 100%의 방제효과를 나타냈다. 처리에 의한 장해를 보면 열처리$(37^{\circ}C)$에서는 장해가 발생하지 많았으며 sodium hypochloride gas 처리에는 배, 귤에서 장해가 나타났으나 사과에서는 발생하지 않았다.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제2권10호
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• pp.661-668
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• 2013

Safety Critical 시스템은 시스템의 기능적인 실패 또는 예기치 못한 상황의 발생으로 인해 인명피해, 재산피해, 환경 피해와 같은 치명적인 사고를 초래할 수 있는 시스템을 의미한다. 그러므로 Safety Critical 시스템의 안전을 보장하기 위해서는 시스템 설계 단계에서 시스템에 존재할 수 있는 위험성들이 충분히 고려되어야 하며, 사고가 발생했을 시 피해를 최소화시키기 위한 일련의 예방 동작들이 설계되어야 한다. 현재에는 Safety Critical 시스템의 설계 단계에서 위험성을 식별하고 분석하기 위한 많은 방법들이 연구되었으며, 이 중에는 예기치 못한 사건으로 인한 피해를 예방하는 동작들의 성공 여부를 분석하는 기법도 존재한다. 본 연구에서는 위의 예방 동작들의 성공 여부에 대한 분석뿐만 아니라 기존 연구들에서 언급하지 못한 예방 동작들 간의 충돌과 이로 인해 발생할 수 있는 피해를 분석하는 방법을 제시하고자 한다. 제안한 방법을 통해 Safety Critical 시스템의 안전성이 견고해지고 피해 예방을 위한 동작들의 올바른 설계에 도움이 될 수 있을 것이다.

• Journal of Ginseng Research
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• 제43권2호
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• pp.326-334
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• 2019

Background: The objective of our study was to analyze the neuroprotective effects of ginsenoside derivatives Rb1, Rb2, Rc, Rd, Rg1, and Rg3 against glutamate-mediated neurotoxicity in HT22 hippocampal mouse neuron cells. Methods: The neuroprotective effect of ginsenosides were evaluated by measuring cell viability. Protein expressions of mitogen-activated protein kinase (MAPK), Bcl2, Bax, and apoptosis-inducing factor (AIF) were determined by Western blot analysis. The occurrence of apoptotic and death cells was determined by flow cytometry. Cellular level of $Ca^{2+}$ and reactive oxygen species (ROS) levels were evaluated by image analysis using the fluorescent probes Fluor-3 and 2',7'-dichlorodihydrofluorescein diacetate, respectively. In vivo efficacy of neuroprotection was evaluated using the Mongolian gerbil of ischemic brain injury model. Result: Reduction of cell viability by glutamate (5 mM) was significantly suppressed by treatment with ginsenoside Rb2. Phosphorylation of MAPKs, Bax, and nuclear AIF was gradually increased by treatment with 5 mM of glutamate and decreased by co-treatment with Rb2. The occurrence of apoptotic cells was decreased by treatment with Rb2 ($25.7{\mu}M$). Cellular $Ca^{2+}$ and ROS levels were decreased in the presence of Rb2, and in vivo data indicated that Rb2 treatment (10 mg/kg) significantly diminished the number of degenerated neurons. Conclusion: Our results suggest that Rb2 possesses neuroprotective properties that suppress glutamate-induced neurotoxicity. The molecular mechanism of Rb2 is by suppressing the MAPKs activity and AIF translocation.