• 임상간호연구
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• 제23권2호
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• pp.202-210
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• 2017

Purpose: In this study an investigation was done of injuries from inpatient falls and diagnostic tests and treatment after falls to identify what factors affect the occurrence of injury from inpatient falls in a tertiary hospital. Methods: Data for this cross-sectional study were retrieved for 428 fall events from data reported between January 1 and December 31, 2015 and were retrieved from the patient-safety reporting system in the hospital's electronic health records. A multivariate logistic regression model was developed with STATA 13.0. Results: Of the patients, 197 (46.0%) had physical injuries due to falls, 119 (27.8%) were given further diagnostic tests, and 358 (83.6%) received treatment including close observation after inpatient falls. Logistic-regression results identified that age, department, and risk factors had significant impact on injuries from falls. Conclusion: Findings indicate that to reduce the severity of injury after inpatient falls, each hospital should regularly evaluate identified factors, design fall-prevention practices specialized for elders and vulnerable patients, and initiate environmental and equipment innovations.

• Child Health Nursing Research
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• 제3권2호
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• pp.131-141
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• 1997

The purpose of this study was to propose for protection of childhood injury or accident and to provide safety measures. Data was collected from 2,052 who visited emergency room of E University Hospital during 1 year period from January to December, 1996. The results were as follows : 1. The most common type of accident was fall down (53.4%). 2. Male patients outnumbered female by the ratio of 1.68 : 1. 3. The highest incidence rate of accidents were observed in children between 1-3 years age group(34.9%). 4. Accidents were seasonally more frequent in spring(28.2%). 5. Accidents mainly took place at home (63%). 6. The time of accidental occurrence appeared to be predominantly high during a day 8 : 00 PM to 0 : 00 AM (35.l%). 7. The most frequent involved part of body was head and face (74%). 8. Most patients discharged from the hospital in good condition(85.4%). Through clinical analysis, in the relation to accident, there were statistically significant difference in sex, age, season, injury place(all p=0.000).

• 임상간호연구
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• 제28권1호
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• pp.45-53
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• 2022

Purpose: The purpose of this study was to evaluate risk factors of pressure injuries in patients after neurosurgery. Methods: A retrospective case-control study was conducted using 273 patients undergoing neurosurgery admitted to a general hospital from 2015 to 2021. Data were collected from September 1 to 30, 2021. The data were analyzed using the SPSS/WIN 26.0 program. Results: Risk factors significantly influencing the occurrence of pressure injuries in the patients undergoing neurosurgery were hypertension (OR=3.12, p=.024), postoperative hypoalbuminemia (OR=0.30, p=.028), and prolonged operative duration (OR=1.00, p=.001). The regression model explained 86.0% of the variance of the outcome variable. Conclusion: In order to prevent surgery-related pressure injuries in patients undergoing neurosurgery, thorough blood pressure management, avoidance of hypoalbuminemia, and preventive nursing intervention considering operative duration are required.

• 한국도로학회논문집
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• 제16권5호
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• pp.143-154
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• 2014

PURPOSES : This study drew factors affecting motorcycle accidents in Seoul by severity using an ordered probit model and aimed to analyze and verify the drawn influence factors. METHODS : As the severity of the accidents could be classified into three types (fatal injury, serious injury and minor injury), this study drew the factors affecting accidents by a comparative analysis employing an ordered probit model, removed the variables that would not secure significance sequentially to construct a model with high explanatory power regarding the factors affecting the severity of motorcycle accidents, and calculated the marginal effect of each factor to understand the degree of each factor's impact on the severity. First, Model 1 put in all variables; Model 2 was constructed by removing the variables of the road surface conditions that could not meet the level of significance (p=0.608); Model 3 was constructed by removing gender variable (p=0.423); and Model 4 was constructed finally by removing age variable (p=0.320). RESULTS : As a result of an analysis, statistically significant variables were time of occurrence, type of accident, road alignment and motorcycle displacement, and it turned out that the impacts on the severity were in the following order: a road alignment of left downhill, the type of motorcycle-to-vehicle accidents and a road alignment of a flatland on the left. The significance of the models was tested using the likelihood ratio, the level of significance and suitability statistics about them, and as a result of the test, the significance level and suitability of the constructed models were all excellent. In addition, the model accuracy indicating the accuracy of a predicted value compared to that of the value actually observed was 70.3% for minor injury; 70.1% for serious injury; and 68.6% for fatal injury, and the overall accuracy was 70.2%, which was very high. CONCLUSIONS : As a result of an analysis of motorcycle accidents in Seoul through the ordered probit model and the marginal effect, it turned out that their severity increased in nighttime accidents as compared to daytime ones and gradually increased in the order of motorcycle-to-vehicle accidents, motorcycle-to-person ones and the ones involving motorcycle only. As a result of an analysis, the severity of accidents in road alignments of left downhill, left flatland and straight downhill increased as compared to those in a road alignment of straight flatland and that the severity of accidents of motorcycles with a displacement larger than 50cc was higher than that of those with a displacement smaller than 50cc.

• 대한약리학회지
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• 제32권2호
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• pp.201-209
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• 1996

Restoration of the blood flow after a period of ischemia is accompanied by generation of toxic oxygen radicals. This phenomenon may account for the occurrence of reperfusion-mediated tissue injury in ischemic hearts. In in vitro studies, although oxygen radicals can be generated from a variety of sources, including xanthine oxidase system, activated leucocytes, mitochondria and others, the most important source and mechanism of oxygen radical production in the post-ischemic reperfused hearts is unclear. In the present study, we tested the hypothesis that the respiratory chain of mitochondria might be an important source of oxygen radicals which are responsible for the development of the reperfusion injury of ischemic hearts. Langendorff-perfused, isolated rat hearts were subjected to 30 min of global ischemia at $37^{\circ}C$, followed by reperfusion. Amytal, a reversible inhibitor of mitochondrial respiration, was employed to assess the mitochondrial contributions to the development of the reperfusion injury. Intact mitochonria were isolated from the control and the post-ischemic reperfused hearts. Mitochondrial oxygen radical generation was measured by chemiluminescence method and the oxidative tissue damage was estimated by measuring a lipid peroxidation product, malondialdehyde(MDA). To evaluate the extent of the reperfusion injury, post-ischemic functional recovery and lactate dehydrogenase(LDH) release were assessed and compared in Amytal-treated and -untreated hearts. Upon reperfusion of the ischemic hearts, MDA release into the coronary effluent was markedly increased. MDA content of mitochondria isolated from the post-ischemic reperfused hearts was increased to 152% of preischemic value, whereas minimal change was observed in extramitochondrial fraction. The generation of superoxide anion was increased about twice in mitochondria from the reperfused hearts than in those from the control hearts. Amytal inhibited the mitochondrial superoxide generation significantly and also suppressed MDA production in the reperfused hearts. Additionally, Amytal prevented the contractile dysfunction and the increased release of LDH observed in the reperfused hearts. In conclusion, these results indicate that the respiratory chain of mitochondria may be an important source of oxygen radical formation in post-ischemic reperfused hearts, and that oxygen radicals originating from the mitochondria may contribute to the development of myocardial reperfusion injury.

• 현장농수산연구지
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• 제23권1호
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• pp.67-80
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• 2021

단감 '부유'의 가을 동상해 발생과 과실생장에 미치는 식재위치의 표고와 농장의 온도환경의 영향과, 서리가 발생한 과수원의 과실 저장 특성을 알아보고자 경남 창원(과원 A)과 창녕(과원 B)의 경사지 과원에서 표고별(상, 중, 하)로 과실특성을 조사하고 서리가 발생한 후 수확한 과실을 MA저장 후 저장특성(품질, 저온장해)을 조사하였다. 수확기 전후(10월25일, 11월5일, 11월20일)에 조사된 두 과원의 과실의 생장 특성(과중, 당도, 경도)은 표고와 농장 요인의 유의미한 영향을 받지 않았다. 과실 착색은 표고 요인의 영향을 받았으며, 과실의 착색(hunter 'a')은 B 과원보다 A 과원에서 더 빨리 진행되었다. 수확기에 발생한 저온으로 인하여 과원 B의 하부에서만 약 2%의 과실에서 동상해 피해가 관찰되었다. 두 과원(A, B)에서 11월 5일과 11월 20일에 수확한 과실을 저밀도 폴리에틸렌 필름을 사용하여 MA저장 한 결과, 저온지 과원(B)보다 고온지 과원(A)의 과실 경도가 높게 유지되었다. 그리고 11월 5일에 수확한 과실은 약 80일 저장 후에도 건전과율이 과원 A에서 약 73%, 과원 B에서 약 85%로 높게 유지되었으나, 11월 20일(서리 발생 후) 수확한 과실은 A 과원의 과실은 약 80일 저장 후에도 76%의 높은 건전과율을 유지하였으나 B 과원의 과실 건전과율은 약 14%에 불과했다.

• 대한임상독성학회지
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• 제18권2호
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• pp.110-115
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• 2020

Purpose: Acute kidney injury (AKI) in patients with glyphosate poisoning has a poor prognosis. This study aimed to predict the risk factors for AKI in patients with glyphosate poisoning at the emergency department (ED). Methods: Clinical data on glyphosate poisoning patients at ED who were older than 18 years were collected retrospectively between January 2013 and December 2019. The clinical characteristics and clinical outcomes of the AKI group in patients with glyphosate poisoning were compared with the non-AKI (NAKI) group. Results: Of 63 glyphosate poisoning patients, AKI was observed in 15 (23.8%). The AKI patients group showed the following: old age (p=0.038), low systolic blood pressure (p=0.021), large amount of ingestion (p=0.026), delayed hospital visits (p=0.009), high white blood cells (WBC) (p<0.001), high neutrophil counts (p<0.001), high neutrophil-lymphocyte (LN) ratios (p<0.001), high serum potassium (p=0.005), low arterial blood pH (p=0.015), and low pO2 (p=0.021), low bicarbonate (p=0.009), and high Poisoning Severity Score (PSS) (p<0.001). AKI patients required hemodialysis, ventilator care (p<0.001, p=0.002), and inotropics (p<0.001). They also showed more intensive care unit admission (p<0.001), longer hospitalization (p<0.001), and high mortality (p<0.001). Logistic multivariate regression analysis showed that high WBCs (OR, 1.223) and increased LN ratios (OR, 1.414) were independently associated with the occurrence of AKI. Conclusion: In patients with glyphosate poisoning at ED, high WBCs and increased LN ratios can help predict the occurrence of AKI.

• Journal of Yeungnam Medical Science
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• 제38권2호
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• pp.136-141
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• 2021

Background: Postoperative acute kidney injury (AKI), which increases the risk of postoperative morbidity and mortality, poses a major concern to surgeons. We conducted this study to analyze the risk factors associated with the occurrence of AKI after orthopedic surgery. Methods: This was a retrospective study that included 351 patients who underwent total hip or knee replacement surgery at Inje University Haeundae Paik Hospital between January 2012 and December 2016. Results: AKI occurred in 13 (3.7%) of the 351 patients. The patients' preoperative estimated glomerular filtration rate (eGFR) was 66.66 ±34.02 mL/min/1.73 m² in the AKI group and 78.07±21.23 mL/min/1.73 m² in the non-AKI group. The hemoglobin levels were 11.21±1.65 g/dL in the AKI group and 12.39±1.52 g/dL in the non-AKI group. Hemoglobin level was related to increased risk of AKI (odds ratio [OR], 0.13; 95% confidence interval [CI], 0.02-0.68; p=0.016). Administration of crystalloid or colloid fluid alone and the perioperative amount of fluid did not show any significant relationship with AKI. Further analysis of the changes in eGFR was performed using a cutoff value of 7.54. The changes in eGFR were significantly related to decreased risk of AKI (OR, 0.74; 95% CI, 0.61-0.89; p=0.002). Conclusion: Renal function should be monitored closely after orthopedic surgery if patients have chronic kidney disease and low hemoglobin level. Predicting the likelihood of AKI occurrence, early treatment of high-risk patients, and monitoring perioperative laboratory test results, including eGFR, will help improve patient prognosis.

• 대한치과의사협회지
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• 제57권1호
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• pp.18-25
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• 2018

Objectives: This study aimed to compare the postoperative pain and clinical performance after partial pulpotomy by using ProRoot MTA and Endocem MTA. Materials and Methods: Twenty-eight teeth requiring partial pulpotomy due to deep dental caries or traumatic injury were included in this study. After 2mm removal of exposed pulp and bleeding control, the ProRoot MTA or Endocem MTA was randomly adjusted to the exposed site. 1, 2, 4, and 12 weeks after the final restoration, the patients were recalled to check the postoperative pain or another unfavorable signs. Pearson's chi-square test was used for statistical analysis to evaluate any differences among tested materials. Results: 3 of 28 teeth showed postoperative pain and cold positive during follow-up period (10.7%). There were no statistically differences in pain occurrence between two tested materials (P > 0.05). Conclusions: In the limitations of this study, partial pulpotomy by using Endocem MTA showed the advantages of short setting time and lower postoperative pain incidence, allowing one visit treatment.

• 한국환경농학회지
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• 제15권4호
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• pp.479-487
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• 1996

$SO_2$에 대한 양버즘나무의 내성을 증대시키고자 생장왜화제인 uniconazole을 토양주입하고, 그 내성 기작을 superoxide dismutase와 peroxidase의 역할과 관련하여 조사했던 바 다음과 같은 결과를 얻었다. Uniconazole은 농도가 높아질 수록 간장, 엽면적 및 T/R율(率)을 현저하게 감소시키고, 엽록소 농도와 superoxide dismutase 및 peroxidase활성을 현저하게 증가시켜 $SO_2$ 처리에 의한 가시피해를 유의성있게 경감시켰다. Diethyldithiocarbamate를 엽면살포하였을때, superoxide dismutase와 peroxidase 활성이 현저하게 불활성화되어 $SO_2$ 처리에 의한 가시피해(可視被害)가 증가되었으며 uniconazole 처리에 의해 증대되었던 $SO_2$ 내성은 diethyldithiocabamate 처리에 의하여 다시 감소되었다. 이상과 같이 uniconazole은 식물생장의 왜화(矮化)에 의한 조직의 치밀화 이외에 SOD와 POD의 활성증대를 통해 $SO_2$에 대한 내성을 증대시킨 것으로 판단된다.