• Title/Summary/Keyword: Injection Site

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Feasibility Study of On-site Analysis on Ammonium ion (암모늄이온의 현장 분석 방법 개발에 관한 기초 연구)

  • Jung, Yong-Jun
    • Journal of Wetlands Research
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    • v.16 no.2
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    • pp.275-280
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    • 2014
  • Because ammonia in water body can cause water pollution as a result of generating ammonium ion, it is of importance in the management of water quality. This work performed to analyze the ammonium ion by measuring the color band length on the basis of modifying the indophenol method. When 1-naphthol was employed as a coloring agent, the maximum absorbance was shown near 720nm, where the proper injection was in the range of 0.5-1.5ml. About 80% of absorbance was observed after the color development was made within the 20 minutes. In the manufacturing of coloring agent, the proper concentration of NaOH was 1.5-2.5M, and the effect of pH on the color development is negligible. In addition, the color development was effectively in the region of room temperature.

Antitumor Activity of Bifidobacterium spp. Isolated from a Healthy Korean

  • Rhee, Young-Kyung;Bae, Eun-Ah;Kim, Suk-Young;Han, Myung-Joo;Choi, Eung-Chil;Kim, Dong-Hyun
    • Archives of Pharmacal Research
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    • v.23 no.5
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    • pp.482-487
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    • 2000
  • The antitumor activity of Bifidobacterium breve K-110, and K-I11, and B. infantis K-525 was investigated. These Bifidobacterial cells and their cell wail preparations (WPG) significantly increased the survival rate of mice who had been intraperitoneally implanted with sarcoma 180 cells. Solid tumor growth was inhibited even when the sarcoma 180 cells were implanted into the groins of the mice. However, the Bifidobacterial cells did not show in vitro cytotoxicity against tumor cell lines. Cell kinetic studies revealed that these WPGs induced neutrophils, which were followed by macrophages, at the site of peritoneal injection. The WPGs directly activated these cells to inhibit the growth of tumor cells in vitro assays. Our results suggest that Bifidobacterial WPGs induce and activate nonspecific phagocytes in situ to reject growing tumor cells in the mouse peritoneal cavity.

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A Study of PKI-Based E-commerce Security System Design under Java Code Environment (Java Code를 중심으로한 PKI기반 전자상거래 보안시스템 설계)

  • Bang, Kee-Chun;Noh, Si Choon
    • Convergence Security Journal
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    • v.13 no.1
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    • pp.51-57
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    • 2013
  • RSA is the most widely used public key algorithms. Payment via the SSL communications, and user authentication using RSA secure shopping mall that can protect the user's valuable information in the process of building. SSL-based electronic signature technology and encryption protocols for this technology are electronic documents are delivered to the other party through a separate encryption process, the information sender to enter information on a web browser (user) and the recipient (the Web server of the site Manager), except you will not be able to decrypt the contents. Therefore, the information is encrypted during the transfer of electronic documents even if hackers trying to Sniffing because its contents can never understand. Of internet shopping mall in the user authentication 'and' Communications' SSL secure shopping mall built with the goal of the methodology are presented.

Comparing the Postoperative Complications, Hospitalization Days and Treatment Expenses Depending on the Administration of Postoperative Prophylactic Antibiotics to Hysterectomy (자궁적출술 후 예방적 항생제 사용 여부별 수술 후 합병증, 재원기간 및 치료비 비교)

  • Jung, Mi Young;Park, Kyung-Yeon
    • Women's Health Nursing
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    • v.23 no.1
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    • pp.42-51
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    • 2017
  • Purpose: This study was conducted to compare postoperative complications, hospitalization days and treatment expenses to postoperative prophylactic antibiotics administrated to hysterectomy or not. Methods: A retrospective survey study was performed with 128 cases in which elective hysterectomy had undergone. They were divided into two groups by identifying whether postoperative prophylactic antibiotics was administered for hysterectomy: a) one group who received postoperative prophylactic antibiotics and; b) those who did not. Data were collected using the electric medical record at a hospital and analyzed by SPSS 23.0 for $x^2$ test, t-test and ANCOVA. Results:Postoperative complications including wound infection (p=1.000), pneumonia (p=.496), hematoma (p=.530), and pneumoperitoneum (p=.496) showed no significant differences between two groups. Hospitalization days for the prophylactic antibioticsadministrated group were significantly longer than the non-administered for prophylactic antibiotics (p=.004). The treatment expenses of the prophylactic antibiotics-administrated group were significantly higher than those of the non-administered prophylactic antibiotics (F=4.31, p=.040). Conclusion: These results can be provided for the evidence of administrating postoperative prophylactic antibiotics to hysterectomy. Additionally, it can contribute to decreasing the medication errors caused by infrequently administrating postoperative prophylactic antibiotics as well as to lessening likelihood of infection of intravenous injection site.

Tools for Web-Based Security Management Level Analysis (웹기반 보안 관리 수준 분석 도구)

  • Kim, Jeom-Goo;Choi, Kyong-Ho;Noh, Si-Choon;Lee, Do-Hyeon
    • Convergence Security Journal
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    • v.12 no.3
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    • pp.85-92
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    • 2012
  • Today, the typical web hacking attacks are cross-site scripting(XSS) attacks, injection vulnerabilities, malicious file execution and insecure direct object reference included. Web hacking security systems, access control solutions, access only to the web service and flow inside but do not control the packet. So you have been illegally modified to pass the packet even if the packet is considered as a unnormal packet. The defense system is to fail to appropriate controls. Therefore, in order to ensure a successful web services diagnostic system development is necessary. Web application diagnostic system is real and urgent need and alternative. The diagnostic system development process mu st be carried out step of established diagnostic systems, diagnostic scoping web system vulnerabilities, web application, analysis, security vulnerability assessment and selecting items. And diagnostic system as required by the web system environment using tools, programming languages, interfaces, parameters must be set.

Scolopendra Pharmacopuncture Ameliorates Behavioral Despair in Mice Stressed by Chronic Restraint

  • Choi, Yu-Jin;Lee, Hwa-Young;Kim, Yunna;Cho, Seung-Hun
    • Journal of Pharmacopuncture
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    • v.20 no.4
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    • pp.257-264
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    • 2017
  • Introduction: Pharmacopuncture, which combines acupuncture with herbal medicine, is one of the newly developed acupuncture techniques that has recently been put into use. The possible mechanisms of scolopendra pharmacopuncture, as well as its potential effects on depressive symptoms, were investigated in this study by using a mouse model of chronic immobilization stress (CIS). Methods: C57BL/6 male mice were randomly assigned into three groups: mice not stressed with restraint and injected with distilled water, mice stressed with restraint and injected with distilled water, and mice stressed with restraint injected with scolopendra pharmacopuncture at a cervical site. Behavioral tests (an open field test, tail suspension test, and forced swimming test) were carried out after two weeks of CIS and injection treatments. The expression levels of glial fibrillary acidic protein (GFAP) in the hippocampus were determined by using western blot and immunohistochemistry analyses. Results: Mice exposed to CIS showed decreased behavioral activity, while scolopendra pharmacopuncture treatment significantly protected against the depressive-like behaviors induced by CIS. Moreover, scolopendra pharmacopuncture treatment increased GFAP protein levels in the hippocampi of the mice stressed by chronic immobilization. Conclusion: Scolopendra pharmacopuncture has an ameliorating effect on depressive behavior, which is partially mediated through protection against glial loss in the hippocampus.

The Hyperthermic Effect of Nitric Oxide in Central Nervous System

  • Jung, Jae-Kyung;Sohn, Uy-Dong;Lee, Seok-Yong
    • The Korean Journal of Physiology and Pharmacology
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    • v.5 no.1
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    • pp.93-98
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    • 2001
  • The precise mechanism of set-point regulation in hypothalamus was not elucidated. Nitric oxide synthases(NOS) were detected in hypothalamus, however, the roles of NO in hypothalamus was not fully studied. So, we tested the effects of NO on body temperature because preoptic-anterior hypothalamus was known as the presumptive primary fever-producing site. NO donor sodium nitroprusside (SNP, 4 nmol, i.c.v.) elicited marked febrile response, and this febrile response was completely blocked by indomethacin (a cyclooxygenase inhibitor). But, ODQ (selective guanylate cyclase inhibitor, $50\;{\mu}g,$ i.c.v.) did not inhibit fever induced by SNP. The cyclic GMP analogue dibutyryl-cGMP $(100\;{\mu}g,\;i.c.v.)$ induced significant pyreses, which is blocked by indomethacin. $N^G-nitro-L-arginine$ methyl ester (L-NAME, non selective NOS inhibitor) inhibited fever induced by $interleukin-1{\beta}\;(IL-1{\bata},\;10\;ng,\;i.c.v.),$ one of endogenous pyrogens. These results indicate that NO may have an important role, not related to stimulation of soluble guanylate cyclase, in the signal pathway of thermoregulation in hypothalamus.

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The Injectable Fibroblast-Hyaluronic Acid Complex for Augmentation Rhinoplasty (Hyaluronic Acid와 배양된 섬유모세포의 혼합주입을 이용한 융비술)

  • Shin, Seung-Han;Han, Seung-Kyu;Lee, Byung-Il;Kim, Woo-Kyung
    • Archives of Plastic Surgery
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    • v.32 no.5
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    • pp.593-598
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    • 2005
  • Although several suspension biomaterials have been considered to be relatively safe and convenient, varying degrees of resorption have required repeated percutaneous injection. In the previous animal study the authors have reported that cultured human fibroblasts suspended in $Restylane^{(R)}$, which is modified hyaluronic acid, could produce human dermal matrices and prolong the effect of this gel. This study was undertaken to evaluate the clinical efficacy of this method. A total of 11 patients ranging from 25 to 57 years of age were included in this study between January of 2002 and December of 2003. All the patients were treated for the purpose of augmentation rhinoplasty. $1{\times}10^7/ml$ or $1.5{\times}10^7/ml$ cultured fibroblasts were suspended in 0.7 to 1.4 ml of $Restylane^{(R)}$. The implants were transferred to a 1-ml syringe and injected subcutaneously to the nose of the patients. Among 11 patients, long term follow-up for more than 1 year was possible in 6 patients. The injected implants remained in site without evidence of resorption or loss of correction. All the patients were satisfied with long term results of this method. There was no complication during the follow-up period.

Perception and Experience of Medication Errors in Nurses with tess than One Year Job Experience (신규 간호사의 투약오류 인지 및 경험에 대한 조사 연구)

  • Oh, Choon-Ae;Yoon, Hae-Sang
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.14 no.1
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    • pp.6-17
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    • 2007
  • Purpose: This study was carried out to investigate perception and experience of medication errors by nurses. Method: Data collection through a survey was performed using structured questionnaires over the period of September 1 to October 15, 2004. Questionnaire were delivered to 222 nurses from 15 hospitals; thereafter, 205 questionnaires were responded (i.e., 92% response rate). The subject in the study was a nurse who had been working in the hospital for less than one year. Results: The average perception rate was 87.5%. The perception rates of subjects in medication errors from four areas are 62% in wrong dosage form for drug administration, 61.5% in air into an IV set, 63% in crystals in an IV lines, and 83.5% in wrong time. The experience rates of subjects in medication errors from four areas are 85.5% in wrong time, 39.5% in wrong injection site, 34.5% in omission error, and 28% in wrong patient. Conclusion: The average perception rate and experience rates of medication errors were 87.5% and 23.5%, respectively. Education about the Five right in medication and knowledges about drugs would improve the perception of medication errors of nurses whose work experience is less than one year, and prevent them from medication errors.

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Perioperative Management of the Voice in Thyroid Cancer (갑상선암 수술과 수술 전후 음성관리)

  • Yoon, So Yeon;Hong, Hyun Jun
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.31 no.2
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    • pp.49-55
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    • 2020
  • Evaluating the patient's voice before thyroidectomy is useful for the purpose of identifying patients with vocal cord paralysis without symptoms, identifying other patient's voice abnormalities, and whether it is related to voice disorders that may occur after surgery. Also voice evaluation after thyroid surgery is helpful in diagnosis, treatment, and rehabilitation and follow-up of voice disorders that occur without clear nerve damage after thyroidectomy. And it is helpful for rapid recovery through active early rehabilitation treatment for patients who complain of speech impairment without paralysis. In particular, neck exercise can improve the adhesion of the surgical site and increase the range of motion of the neck as well as improve subjective neck discomfort. In addition, hearing, voice and breathing functions should be improved, and voice hygiene education and counseling should be provided. Vocal cord injection is the first treatment option for unilateral vocal cord palsy. By establishing a protocol for voice disorders before and after thyroid surgery and providing appropriate treatment, the quality of life of patients can be improved.