• The Journal of Advanced Prosthodontics
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• v.5 no.4
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• pp.374-381
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• 2013

PURPOSE. The purpose of this study was to evaluate the effect of alendronates on bone remodeling around titanium implant in the maxilla of rats. MATERIALS AND METHODS. The maxillary first molars were extracted and customized-titanium implants were placed immediately in thirty male Sprague-Dawley rats. The rats were divided into experimental (bisphosphonate) group and control group. At 4 weeks after implantation, the rats in the bisphosphonate group were subcutaneously injected with alendronate three times a week for 6 weeks where as the rats in control group were injected with saline. The rats were sacrificed at 1, 2, 3, 4, or 6 weeks after starting of injection and maxillary bones were collected subsequently. Alveolar bone remodeling around the implants were evaluated by radiographic and histologic analysis. Microarray analysis and immunohistomorphologic analysis were also performed on one rat, sacrificed at 6 weeks after starting of injection, from each group. Statistical analysis was performed using repeated measures analysis of variance and independent t test at a significance level of 5%. RESULTS. There was no statistically significant difference in the bone area (%) around implant between the bisphosphonate group and the control group. However, the amount of empty lacuna was significantly increased in the bisphosphonate group, especially in the rats sacrificed at 4 weeks after starting of injection compared to that of the corresponding control group. The bisphosphonate group showed the same level of TRAP positive cell count, osteocalcin and angiopoietin 1 as the control group. CONCLUSION. Alendronate may not decrease the amount of osteoclast. However, the significantly increased amount of empty lacuna in the bisphosphonate group may explain the suppression of bone remodeling in the bisphosphonate group.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.3
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• pp.390-401
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• 2000

In this study, numerical calculation is carried out to investigate the influence of injection timing, fuel amount, intake $O_2$ concentration, and EGR on Nitric Oxide(NO) formation using a two-zone model in a diesel engine. Results can be summarized as follows. The NO formation is very sensitive to the burned gas temperature, so multi-zone model must be applied to combustion process to predict the burned gas temperature exactly. Since the burned gas temperature increases rapidly during the premixed combustion, most NO is formed within 20 crank angle degrees after ignition. As the injection timing is retarded, the combustion occurs later in the expansion process which causes the decrease of burned gas temperature and, as a result, NO formation decrease. The increase of fuel amount results in the increase of earlier formation of NO in the engine. As the intake $O_2$ concentration increases, the maximum pressure and burned gas temperature increase due to activate combustion. And, [O] mole fraction of equilibrium combustion products also increase. Therefore NO exponentially increases. If exhaust gas is recirculated, the burned gas temperature decreases which results in NO decrease. If exhaust gas is cooled, more NO can be decreased.

• The Korean Journal of Nuclear Medicine
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• v.16 no.1
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• pp.55-61
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• 1982

Biodistribution studies has been carried out to elucidate the cause of poor bone imagings often encountered in using $methylenediphosphonate(MDP)-^{99m}Tc$ and to establish effective conditions in using the popular bone imaging agent. After 150 minutes from the I.V. injection of $MDP-^{99m}Tc$ to mice, the radioactivities accumulated at bone(B), liver(L), and stomach(S) were counted. The radiochemical purity (RCP), the volume, the radioactivity concentration and the amount of radioactivity of $MDP-^{99m}Tc$ were controlled. Data were expressed either in %cpm/g organ or % cpm/organ. The organ distribution ratios(B/L and B/S) were correlated with the RCP, the volume of injection, the radioactivity concentration etc. Results indicated that the RCP plays a major role in biodistributions. High radioactivity concentration and injection of a small amount is recommended. Negligible effect was observed with the amount of radioactivity. It has been confirmed that the up-to-date methods of RCP determinations cannot sensitively detect the sharply affecting trace impurities. A particular biodistribution pattern of crossed B/L and B/S lines was observed in case of using $MDP-^{99m}Tc$ of low RCP. In such a case, rather a higher dosage would be effective for improving the contrast between bone and liver.

• Journal of Advanced Marine Engineering and Technology
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• v.34 no.1
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• pp.37-45
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• 2010

Computational simulation has been carried out to examine the effects of pilot injection to reduce both of NOx and Soot emissions in a marine diesel engine. For verification of the computational result, calculated cylinder pressure was matched to experimental pressure. In this study, the primary variables were injection timing, dwell time and injection rate while the amount of injection fuel was maintained constant. It was revealed that variation of pilot injection timing affects auto ignition and heat release rate. In the results, both of NO and soot emission were reduced without deterioration of in-cylinder pressure under the condition of $10^{\circ}$CA dwell time and 0.022kg/s injection rate.

• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.3
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• pp.210-219
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• 2014

The MPI dual injection engine can enhance the fuel efficiency and engine power. By using one injector per one intake port, MPI dual injection engine has an excellent fuel atomization and targeting injection. As the basic research for the MPI Dual injection engine design, this research was investigated in order to understand the characteristic of the in-cylinder flow and fuel behavior according to engine temperature condition and the fuel type in the MPI dual injection engines. The 3D unsteady CFD simulation for the MPI Dual injection engine was performed using STAR-CD. The engine operating condition was 2,000 rpm/WOT. The parameters for this study were fuel types, fuel temperatures and wall temperatures. As a result, the intake air amount, evaporated fuel in the cylinder and the fuel film on the wall were presented according to parameters that depend on the fuel properties and engine wall temperature. Also, the results were influenced by in-cylinder flow such as the intake flow, back flow and so on.

• Elastomers and Composites
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• v.38 no.4
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• pp.295-302
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• 2003

The amount of shrinkage of injection molded parts is different from operational conditions of injection molding such as injection temperature, injection pressure and mold temperature, and mold design such as gate size. It also varies depending on the presence of crystalline structure in resins. In this study, part shrinkage was investigated for various operational conditions and resins. Poly(butylene terephthalate) (PBT) for crystalline polymer, and polycarbonate (PC) and poly(methyl methacrylate) (PMMA) for amorphous polymers were used. Crystall me polymer showed higher part shrinkage by about three times than that of amorphous polymers. Part shrinkage increased as melt and molt temperatures increased, and injection pressure decreased. Part shrinkage decreased as gate size increased since the pressure delivery is mush easier for larger gate sizes. Part shrinkage at the position close to the gate was larger than that or the position far from gate. This phenomenon might be occur by difference of residual stress.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.6
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• pp.155-165
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• 2013

The effect of gaseous ammonia direct injection on the engine performance and exhaust emissions in gasoline-ammonia dual fueled spark-ignition engine was investigated in this study. Results show that based on the gasoline contribution engine power increases as the ammonia injection timing and duration is advanced and increased, respectively. However, as the initial amount of gasoline is increased the maximum power output contribution from ammonia is reduced. For gasoline-ammonia, the appropriate injection timing is found to range from 320 BTDC at low loads to 370 BTDC at high loads and the peak pressures are slightly lower than that for gasoline due to the slow flame speed of ammonia, resulting in the reduction of combustion efficiency. The brake specific energy consumption (BSEC) for gasoline-ammonia has little difference compared to the BSEC for gasoline only. Ammonia direct injection causes slight reduction of $CO_2$ and CO for all presented loads but significantly increases HC due to the low combustion efficiency of ammonia. Also, ammonia direct injection results in both increased ammonia and NOx in the exhaust due to formation of fuel NOx and ammonia slip.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2006.06a
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• pp.67-68
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• 2006

This study suggests a precision flow control system that enables fluid injection of a few grams at a time in a few ms time duration. The fluid injection system suggested here consists of a high pressure fluid pump, a 3 way 3 position directional control valve, an injector and an orifice. The orifice is located between the directional control valve and the injector. By supplying current signal to the directional control valve, the prescribed small amount of fluid can be supplied to a plant through the injector. The control robustness of the suggested system against the disturbances like the pressure change in a plant and the viscosity variation of the injected fluid is secured easily by using an orifice with very small inside diameter and setting the supply pressure with comparatively high value. The control performances of the suggested system are verified by numerical simulations and experiments. The outcomes of this research could be applied to the common rail injection control of lubrication oil for large size marine diesel engines, and other industrial plants.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.7
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• pp.1702-1708
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• 1995

Owing to the serious problem of hydrocarbon fuel such as environmental pollution, the development of alternative fuel is very urgent. To adopt hydrogen to the internal combustion engine, a solenoid-drive type in-cylinder injection system was constructed. The injection system was installed to the single cylinder research engine, and the engine performance and the emission of citric oxide were tested upon the fuel-air equivalence ratio and the spark timing. In the case of in-cylinder injection system, hydrogen is injected after the intake valve is close, so it is possible to operate the engine without the back fire and the fall of its volumetric efficiency. In the region of the fuel-air equivalence ratio below 0.5, hydrogen and air aren't well mixed and the thermal efficiency is lowered, so the nozzle should be designed to inject hydrogen uniformly into the combustion chamber. In the region of the fuel-air equivalence ratio above 0.7,the fuel-air mixture burns very fast and the amount of citric oxide emission increases rapidly, so the spark timing should be retarded as compared with MBT.

• Transactions of the Korean Society of Automotive Engineers
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• v.20 no.5
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• pp.130-137
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• 2012

Automotive engines need strategies to satisfy with the emission regulations in terms of PM and NOx. HC-LNT (Hydrocarbon-Lean NOx Trap) with secondary injection system is considered as more practical technology in order to cope with emission regulations. The HC-LNT system, which is using diesel fuel itself as a reducing agent, absorbs NOx in lean exhaust gas condition and releases NOx in rich exhaust gas conditions. In this system, inappropriate amounts of reducing agent will slip through the LNT without the profits of conversion and cause additional emission problems. Therefore, the suitable amount of reducing agent should be supplied into the catalytic converter. In this research, engine emission test was conducted to optimize injection quantity at the various engine test conditions. Different exhaust layouts and catalyst shapes have been studied and extension unit which makes better uniformity of exhaust gas was used for HC-LNT system. From this results, the effect of secondary injection conditions on NOx conversion characteristics of HC-LNT was clarified.