• 한국가스학회지
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• 제9권4호
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• pp.57-61
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• 2005

이 연구는 결함수분석(FTA)를 이용해 완전방호 형식 및 멤브레인 형식의 KOGAS 탱크 설계에 대한 비교 정량적 위험성평가를 위해 수행하였다. 이 연구를 위해 표준 완전방호식 탱크와 초기 멤브레인 탱크 및 4가지의 개선된 멤브레인 탱크를 포함한 총 6개 모델에 대해 위험성을 평가하였다. 이 연구에서는 FTA를 이용해 누출빈도를 정량화 하였다. 분석의 명확성 및 일관성을 위해서 모든 경우는 동일한 고장수(fault tree)를 이용해 정량화하였다. 개선되지 않은 멤브레인 저장탱크(초기 모델)를 제외하고 예측된 위험도 수준은 매우 유사해서 각각의 탱크는 동일한 위험도 수준(the same level of risk)을 나타내는 것으로 평가되었다. 펌프 낙하에 의한 손상은 완전방호식 탱크에 비해서 박판으로 되어있는 멤브레인 탱크가 두드러지게 큰 것으로 예측되었다.

• 대한임상독성학회지
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• 제4권2호
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• pp.107-112
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• 2006

Purpose: In many Korean hospitals, serum acetaminophen concentrations in cases of overdose cannot be measured initially because of inadequate laboratory facilities. Under these circumstances, physicians base the administration of the antidote, N-acetylcysteine, on ingestion amounts as determined by initial history taking. We therefore examined the correlated between ingested amounts and serum acetaminophen concentrations. Methods: Medical records were reviewed retrospectively for patients who presented to the ED with acetaminophen overdose between January 2002 and March 2006. Fifty-nine patients were recruited and sixteen patients were excluded. The forty-three remaining patients were placed into either the high-risk or low-risk group based on their ingested amount (140 mg/kg), and were separately categorized into the toxic or non-toxic group based on their serum acetaminophen concentrations, according to the Rurnack-Matthew nomogram. Results: Ten patients (83.3%) among twelve in the high-risk group were found to have non-toxic serum concentrations, and just one patient (3.2%) among thirty-one in the low-risk group fell into the toxic group based on their serum concentrations. The sensitivity and specificity of risk stratification of the ingested amount as a predictor of intoxication requiring antidote therapy were 66.7% and 75.0%, respectively. Conclusion: This study suggests that the therapeutic decision for acetaminophen overdose should not be based solely on ingested amount only, but requires assessment of acetaminophen concentration.

• 대한치매학회지
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• 제23권3호
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• pp.146-160
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• 2024

Background and Purpose: The emotions of people at various stages of dementia need to be effectively utilized for prevention, early intervention, and care planning. With technology available for understanding and addressing the emotional needs of people, this study aims to develop speech emotion recognition (SER) technology to classify emotions for people at high risk of dementia. Methods: Speech samples from people at high risk of dementia were categorized into distinct emotions via human auditory assessment, the outcomes of which were annotated for guided deep-learning method. The architecture incorporated convolutional neural network, long short-term memory, attention layers, and Wav2Vec2, a novel feature extractor to develop automated speech-emotion recognition. Results: Twenty-seven kinds of Emotions were found in the speech of the participants. These emotions were grouped into 6 detailed emotions: happiness, interest, sadness, frustration, anger, and neutrality, and further into 3 basic emotions: positive, negative, and neutral. To improve algorithmic performance, multiple learning approaches were applied using different data sources-voice and text-and varying the number of emotions. Ultimately, a 2-stage algorithm-initial text-based classification followed by voice-based analysis-achieved the highest accuracy, reaching 70%. Conclusions: The diverse emotions identified in this study were attributed to the characteristics of the participants and the method of data collection. The speech of people at high risk of dementia to companion robots also explains the relatively low performance of the SER algorithm. Accordingly, this study suggests the systematic and comprehensive construction of a dataset from people with dementia.

• Journal of Preventive Medicine and Public Health
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• 제32권3호
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• pp.289-296
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• 1999

Objectives: This study describes the risk factors affecting the unexpected readmission of 261 patients who were discharged from a university hospital in Seoul. Methods: This case-control study reviewed medical records of inpatients who had been discharged from a hospital between 1 August 1995 and 31 October 1995 after the treatment for general diseases. The cases were 68 patients who were readmitted unexpectedly within 28 days of discharge from an index stay, and the controls were 193 Patients who were discharged without readmission during the study period. Results: Logistic regression analysis results were as follows; Patients who had no operation during their hospital stay were more likely to be readmitted unexpectedly than patients who had operation. Patients who had 1 or 2 parts of their body being involved in treatment were more likely to be readmitted unexpectedly than patients who hand more than 3 parts of their body being involved in treatment. Patients who had complications after surgery were more likely to be readmitted unexpectedly than patients who had no complications. Insufficient discharge planning caused unexpected readmissions. Conclusions: Discharge planning education should be extended to health care providers. And the assessment of discharge planning should be evaluated. Readmission is often necessary for the treatment of related problems of originating from initial hospitalization, which causes cost problems. Unexpected readmission is preventable and the models for readmission can serve as a valuable clinical tool for high risk patients.

• 한국환경성돌연변이발암원학회지
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• 제24권3호
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• pp.137-142
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• 2004

Dioxin-like compounds are ubiquitous environmental polltants that could be accumulated in biological system and toxic to human and wildlife. Given this issue, it is important to develop a reliable dioxin detection methods for a rational risk assesment of dioxin-like compounds. In this study, we tried to set up and validate a sensitive, reliable risk assessment of dioxin-like compounds. In this study, we tried to set up and validate a sensitive, reliable and rapid bioassay model, CALUX bioassay as a screening tool for routine measurement of dioxin-like conpounds in environmental matrices. For the valisation of CALUX bioassay, firstly, we performed dose-response assay for 2,3,7,8-TCDD, most potent dioxin-like compound, using two different methods CALUX and EROD assay. Induction of luciferase activity and CYPIA catalyzed EROD activity were dose-dependently induced by 2,3,7,8-TCDD, with initial induction at 0.1 pM and maximal induction at 1 nM. In order t determine whether the CALUX bioassay could predict the effects of dioxin-like compounds, 2,3,7,8-TCDD dose-response from CALUX was compared with that from EROD assay. The correlation coefficient ($r^2$) was found to be 0.89, indicating a good correlation between two different methods and the possibility of CALUX bioassay as a useful dioxin detecting method.

• 한국의료질향상학회지
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• 제19권2호
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• pp.50-64
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• 2013

Objectives : Suicide is a serious sentinel event in healthcare organization. Suicide and suicidal attempt are fatal and long lasting mental and physical damage to themselves, family, and medical staffs. To develope the system to prevent suicidal accident in hospital, we reviewed and analysed one case of suicidal sentinel event. Methods: The risks of suicidal sentinel event were evaluated and analysed through the root cause analysis and failure mode effects analysis. Result: We found several root causes such as initial assessment of oldest patient and security issues. Couple of action plans to fix the problems were done immediately. According to failure mode, we evaluate the risk priority number to modify the action plans. Conclusion: To reduce the risk of sentinel events, we reviewed the suicidal event and established the new system and action plan to prevent sentinel events.

• Parasites, Hosts and Diseases
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• 제54권6호
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• pp.733-742
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• 2016

Acquaintance is scanty on primaquine (PQ) efficacy and Plasmodium vivax recurrence in Udupi district, Karnataka, India. We assessed the efficacy of 14 days PQ regimen (0.25 mg/kg/day) to prevent P. vivax recurrence. Microscopically, aparasitemic adults (${\geq}18years$) after acute vivax malaria on day 28 were re-enrolled into 15 months' long follow-up study. A peripheral blood smear examination was performed with participants at every 1-2 month interval. A nested PCR test was performed to confirm the mono-infection with P. vivax. Of 114 participants, 28 (24.6%) recurred subsequently. The median (IQR) duration of the first recurrence was 3.1 (2.2-5.8) months which ranged from 1.2 to 15.1 months, including initial 28 days. Participants with history of vivax malaria had significantly higher risk of recurrence, with hazard ratio (HR) (95% CI) of 2.62 (1.24-5.54) (P=0.012). Severity of disease (11.4%, 13/114) was not associated (P=1.00) with recurrence. Of 28 recurrence cases, the nPCR proved that P. vivax mono-infection recurrence rate was at least 72.7% (16/22) at first recurrence. In Udupi district, PQ dose of 0.25 mg/kg/day over 14 days seems inadequate to prevent recurrence in substantial proportion of vivax malaria. Patients with a history of vivax malaria are at high risk of recurrences.

• Nuclear Engineering and Technology
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• 제51권1호
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• pp.104-115
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• 2019

Since the Fukushima Daiichi accident, there has been an emphasis on the risk resulting from multi-unit accidents. Human reliability analysis (HRA) is one of the important issues in multi-unit probabilistic safety assessment (MUPSA). Hence, there is a need to properly identify all the human and organizational factors relevant to a multi-unit incident scenario in a nuclear power plant (NPP). This study identifies and categorizes the human and organizational factors relevant to a multi-unit incident scenario of NPPs based on a review of relevant literature. These factors are then analyzed to ascertain all possible unit-to-unit interactions that need to be considered in the multi-unit HRA and the pattern of interactions. The human and organizational factors are classified into five categories: organization, work device, task, performance shaping factors, and environmental factors. The identification and classification of these factors will significantly contribute to the development of adequate strategies and guidelines for managing multi-unit accidents. This study is a necessary initial step in developing an effective HRA method for multiple NPP units in a site.

• 대한건축학회논문집:구조계
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• 제35권2호
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• pp.3-11
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• 2019

The recent earthquake of Pohang (M5.4) and the Gyeongju earthquake (M5.8) suggested the possibility of a strong earthquake in Korea and reminded us that the Korea is no longer an earthquake-safe zone. In the disaster recovery stage in a disaster like an earthquake, the investigation of the damage situation and the safety assessment of the building serve to provide important information for the initial action such as establishment of the recovery strategy and rescue of the survivor. However, the research that depends on manpower can not cope with the difficulty of processing a large number of doses in a short time, and the expertise of the manpower must be taken into consideration, which may result in delayed initial action. In this study, we propose an rapid safety evaluation technique of building using unmanned aerial vehicle which evaluates the performance and safety of buildings by integrating conventional safety inspection method with unmanned aerial vehicle technology and developed evaluation method of each evaluation factor. In order to verify this, the buildings damaged by the earthquake in Pohang were checked and compared using this system. The results are consistent with the results of the existing emergency earthquake risk assessment. As a result, the possibility of checking the emergency safety using the unmanned aerial vehicle for the damaged structures in case of a large-scale disaster such as an earthquake was confirmed.

• 대한토목학회논문집
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• 제39권6호
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• pp.751-758
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• 2019

본 연구는 오염부지의 위해성 평가를 위해 수치모의 기반 오염물질의 노출이동경로 평가에 활용가능한 개념모델을 제시하였다. 이를 위하여 1차원으로 유한차분 기법을 적용하여 지하수 내 오염물질 이송확산을 모의하였다. 불포화대 경로에서의 수리지질학적 및 오염물질 매개변수가 가질 수 있는 범위를 설정하여 범용 시나리오 및 오염물질별 시나리오를 구성하여 모의에 적용하였다. 모델에서는 흡착 및 생분해를 갖는 유한차분 1 차원 이송확산이 고려되었고, 또한 초기 농도가 시간이 지남에 따라 고갈되는 것을 가정하였다. 일반 시나리오의 결과는 지하수 침투율이 감소함에 따라, 오염원에서 지하수면까지의 경로가 길어질수록 지하수면으로 유입되는 지점의 농도 범위는 낮아졌다. 특히, 높은 생분해 속도와 오염원의 빠른 고갈의 경우, 범용 시나리오가 좁은 범위의 지하수 유입농도 예측치를 보여주었다.