• 제목/요약/키워드: Initial factor

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부부간 역기능적 의사소통 행동 척도 개발 - Gottman의 네 기수(騎手) 개념을 중심으로 - (Development of the Dysfunctional Communication Behavior Scale for Married Couples - Focusing on Gottman's Four Horsemen of the Apocalypse -)

  • 권윤아;김득성
    • 대한가정학회지
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    • 제46권6호
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    • pp.101-114
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    • 2008
  • The purpose of this study was to develop a self-report scale measuring dysfunctional communication behaviors that Korean husbands and wives may use during marital fights. Based on the four concepts of criticism, contempt, defensiveness, and stonewalling proposed by Gottman(1994a), an initial pool of 38 items was developed. Through expert reviews of the 38 items to assess content validity, preliminary 30 items were selected. Using a sample of 89 married couples who were living in Susan, Korea, we conducted item analyses and exploratory factor analyses with the 30 items. These analyses yielded a final 19-item, four-factor scale : criticism(5 items), contempt(5 items), defensiveness(5 items), and stonewalling(4 items). The internal consistency estimates for these subscales were satisfactory. Finally, using another sample of 228 wives, we conducted confirmatory factor analysis to confirm cross validity of the 19-item, four-factor model. The result indicated that this model fitted the data reasonably well. All standardized factor loadings were significant in this model. The results of this study supported reliability and validity of this scale.

유방암여성 임파워먼트 측정도구 개발 및 타당화 (Development and Validation of the Empowerment Scale for Woman with Breast Cancer)

  • 신선화;박효정
    • 대한간호학회지
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    • 제45권4호
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    • pp.613-624
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    • 2015
  • Purpose: The purpose of this study was to develop a scale to evaluate empowerment in woman with breast cancer and to examine the validity and reliability of the scale. Methods: The development process for the initial items included a literature review, interviews, and construction of a conceptual framework. The identified items were evaluated for content validity by experts, resulting in 3 factors and 48 preliminary items. Participants were 319 women with breast cancer recruited to test reliability and validity of the preliminary scale. Data were analyzed using item analysis, confirmatory factor analysis, criterion related validity, internal consistency and test-retest reliability. Results: The final scale consisted of 30 items and 3 factors. Factors, including 'intrapersonal factor' (14 items), 'interactional factor' (8 items), and 'behavioral factor' (8 items), were drawn up after confirmatory factor analysis. Goodness of fit of the final research model was very appropriate as shown by ${\chi}^2/df=1.86$, TLI=.90, CFI=.92, SRMR=.06, and RMSEA=.05. Criterion validity was evaluated by total correlation with the Cancer Empowerment Questionnaire .78. Cronbach's alpha for total items was .93 and test-retest reliability was .69. Conclusion: Findings from this study indicate that the scale can be used in the development of nursing interventions to promote the empowerment of women having breast cancer.

Solvent/Detergent Inactivation and Chromatographic Removal of Human Immunodeficiency Virus During the manufacturing of a High Purity Antihemophilic Factor VIII concentrate

  • Kim, In-Seop;Park, Yong-Woon;Woo, Hang-Sang;Chong E. Chang;Lee, Soungmin
    • Journal of Microbiology
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    • 제38권3호
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    • pp.187-191
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    • 2000
  • A validation study was conducted to determine the efficacy of solvent/Detergent (S/D) inactivation and Q-Sepharose column chromatographic removal of the human immunodeficiency virus (HIV) during the manufacturing of a high purity antihemopilic factor VIII (GreenMono) from human plasma. S/D treatment using the organic solvent, tri (n-butyl) phosphate, and the detergent, Trition X-100, was a robust and effective step in eliminating HIV-1. The HIV-1 titer was reduced from an initial titer of 8.3 log10 TCID50 to undetectable levels within one minute of S/D treatment, HIV-1 was effectively partitioned form factor VIII during Q-Sepharose column chromatography with the log reduction factor of 4.1 . These results strongly assure the safety of GreenMono From HIV.

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Dynamic load concentration caused by a break in a Lamina with viscoelastic matrix

  • Reza, Arash;Sedighi, Hamid M.;Soleimani, Mahdi
    • Steel and Composite Structures
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    • 제18권6호
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    • pp.1465-1478
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    • 2015
  • The effect of cutting off fibers on transient load in a polymeric matrix composite lamina was studied in this paper. The behavior of fibers was considered to be linear elastic and the matrix behavior was considered to be linear viscoelastic. To model the viscoelastic behavior of matrix, a three parameter solid model was employed. To conduct this research, finite difference method was used. The governing equations were obtained using Shear-lag theory and were solved using boundary and initial conditions before and after the development of break. Using finite difference method, the governing integro-differential equations were developed and normal stress in the fibers is obtained. Particular attention is paid the dynamic overshoot resulting when the fibers are suddenly broken. Results show that considering viscoelastic properties of matrix causes a decrease in dynamic load concentration factor and an increase in static load concentration factor. Also with increases the number of broken fibers, trend of increasing load concentration factor decreases gradually. Furthermore, the overshoot of load in fibers adjacent to the break in a polymeric matrix with high transient time is lower than a matrix with lower transient time, but the load concentration factor in the matrix with high transient time is lower.

가열판 압체식 진공건조에서 침엽수 제재두께와 건조속도 및 건조시간계수의 관계 (Relationship between Softwood Lumber Thicknesses and Drying Rate and Drying Time Factor in Vacuum-Press Drying)

  • 정희석;이준호;강욱;이남호
    • Journal of the Korean Wood Science and Technology
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    • 제29권1호
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    • pp.1-8
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    • 2001
  • 소나무, 잣나무, 낙엽송과 웨스턴 햄록의 5두께(3, 5, 7, 9 및 11cm) 제재를 3가지 종류의 건조스케줄을 적용한 가열판 압체식 진공건조에서 건조중 함수율, 제재두께와 건조속도의 관계, 제재두께와 건조시간계수의 관계 등을 구명한 결과에서 제재두께 초기함수율 및 건조시간에 따른 건조중 함수율을 추정할 수 있었다. 그리고 함수율 30%에서 15% 범위에서 평균 건조속도는 웨스턴 햄록이 가장 컸고 다음은 소나무, 잣나무, 낙엽송 순위였으며, 제재두께가 증가함에 따라 곡선적으로 감소하였다. 또한 건조시간계수는 제재두께가 증가함에 따라 곡선적으로 증가하였다.

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선형열원법에 의한 지중유효열전도도와 보어홀 전열저항 해석 (Analysis of Effective Soil Thermal Conductivities and Borehole Thermal Resistances with a Line Source Method)

  • 이세균;우정선;노정근
    • 한국태양에너지학회 논문집
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    • 제30권4호
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    • pp.71-78
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    • 2010
  • Investigation of the effective soil thermal conductivity(k) is the first step in designing the ground loop heat exchanger(borehole) of a geothermal heat pump system. The line source method is required by New and Renewable Energy Center of Korea Energy Management Corporation in analyzing data obtained from thermal response tests. Another important factor in designing the ground loop heat exchanger is the borehole thermal resistance($R_b$). There are two methods to evaluate $R_b$ : one is to use a line source method, and the other is to use a shape factor of the borehole. In this study, we demonstrated that the line source method produces better results than the shape factor method in evaluating $R_b$. This is because the borehole thermal resistance evaluated with the line source method characteristically reduces the temperature differences between an actual and a theoretical thermal behaviors of the borehole. Evaluation of $R_b$ requires soil volumetric heat capacity. However, the effect of the soil volumetric heat capacity on the borehole thermal resistance is very small. Therefore, it is possible to use a generally accepted average value of soil volumetric heat capacity($=2MJ/m^3{\cdot}K$) in the analysis. In this work, it is also shown that an acceptable range of the initial ignoring time should be in the range of 8~16hrs. Thus, a mean value of 12 hrs is recommended.

CDSK 방식의 디지털 카오스 통신 시스템 (Digital Chaotic Communication System Based on CDSK Modulation)

  • 복준영;유흥균
    • 한국통신학회논문지
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    • 제38A권6호
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    • pp.479-485
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    • 2013
  • 최근 정보 보안이 중요시됨에 따라서 향상된 보안성과 낮은 도청 확률을 가지는 무선 통신 기술에 대한 관심이 급격히 증가하고 있다. 카오스 신호는 불규칙한 현상으로 인하여 정보를 효율적으로 부호화 하는데 적용할 수 있다. 카오스 신호는 초기 조건에 매우 민감하며 초기 조건을 모른다면 신호의 감지가 어렵다는 단점을 가지고 있지만 다중 경로 간섭에 강한 장점을 가진다. 본 논문에서는 디지털 카오스 변조 방식인 CDSK 방식에서 여러 가지 카오스 맵을 적용하여 수신 성능을 평가한다. 또한, CDSK 방식에서 확산인자 (Spreading factor)의 변화에 따른 수신 BER 성능을 분석한다. 시뮬레이션 결과, Hennon map을 사용할 경우 다른 Chaotic map들 보다 훨씬 좋은 수신 성능을 얻을 수 있었으며, 확산인자가 70에서 가장 좋은 수신 BER 성능을 얻는 것을 확인하였다.

응력확대계수와 J-적분 결정을 위한 코스틱스방법의 실험조건에 관한 연구 (Revisit on Experimental Conditions in Determination of Stress Intensity Factor and the J-Integral Using the Methods of Caustics)

  • 이억섭;조종두;홍성경
    • 대한기계학회논문집
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    • 제18권9호
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    • pp.2331-2338
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    • 1994
  • Experimental conditions of the optical shadow methods of caustics for measurement of the stress intensity factor and the J-integral in various materials(polycarbonate, PMMA, Al 5586D) are investigated. The necessary experimental requirements toe determine accurate values of the stress intensity factors and the J-integrals are described. The ratio of $r_o$ (radius of initial curve) to $r_p$ (plastic zone size) is selected as a parameter to verify the experimental limitation of the method of caustics in determination of fracture parameters. In this study, transmission caustics method was used for compact tension specimens made of polycarbonate and PMMA. while reflection caustics method was applied to c-shaped tension specimen made of Al 5586D. The appropriate ranges of $r_o/r_p$ tp determine accurate values of stress intensity factors were found to be 1.5~1.8. Existing experimental results have been obtained mainly by changing $r_p$ with different loads in $r_o/r_p$. However, in this study we could obtain varying $K_{caus}/K_{th}$ over the wide range of $r_o/r_p$ at fixed load conditions with newly designed optical arrangement. Thus, we could find the range in which theoretical and experimental results agree well each other by changing $r_o$ values only. In Al 5586D specimen, experimental caustics were located inside of the plastic zone, and $K_{caus}/K_{th}$ were found to be not unity in this range. It is found that $J_{caus}/J_{th}=1{\;}with{\;}r_o/t{\geq}0.8$ and the experimental plastic zone includes the contours of caustics.

Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis

  • Alsayed, Mona Abdel Latif;Elbeah, Shymaa Mohsen;El-Desoky, Manal M.;Elziny, Shereen Magdy;Megahed, Ahmed
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제23권1호
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    • pp.63-71
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    • 2020
  • Purpose: Autoimmune hepatitis (AIH) is a chronic disease that may lead to cirrhosis. The immunopathogenesis of AIH is not fully understood and it mainly involves T-cell mediated mechanism. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that promotes T cell response and its polymorphism may serve as a severity marker of AIH. No previous study has considered investigating MIF polymorphism in children with AIH. Methods: Forty-two children with definite diagnosis of AIH were enrolled along with 100 age and sex matched controls. All participants were tested for polymorphism at -173GC (rs755622) of MIF gene. All patients received the standard protocol of steroid plus azathioprine to achieve remission. Liver biopsy was performed at time of diagnosis for all patients and only 18 of them underwent a second biopsy after treatment. Results: No statistically significant differences in the frequency of the genotypes GG and GC or in allele distribution were found in both patient and control groups (p=0.590, 0.640 respectively). Initial alanine aminotransferase (ALT) levels at the time of presentation was significantly higher in the GC group than GG group (p=0.020). GC genotype significantly correlated with disease relapse (r=0.41, p=0.007). Regression of necroinflammation and the fibrosis score in the second liver biopsy was statistically significant in the GG group (p<0.0001, p=0.010 respectively). Conclusion: MIF -173GC polymorphism is associated with clinically significant markers of pediatric AIH, including increased initial serum ALT levels, may help predict necroinflammatory/fibrosis regression effectively, following immunosuppressive treatment.

하악골 신장술 후 하치조신경의 조직학적 변화와 신경성장인자의 발현에 대한 연구 (HISTOLOGICAL CHANGES AND EXPRESSION OF NERVE GROWTH FACTOR IN THE INFERIOR ALVEOLAR NERVE AFTER DISTRACTION OSTEOGENESIS)

  • 박봉욱;김종렬;변준호
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제27권5호
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    • pp.415-423
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    • 2005
  • Distraction osteogenesis (DO) is frequently used technique in reconstruction of bony defects resulted from tumor resection, congenital deformity, and trauma in the maxillofacial region. Although the histologic and ultrastructural changes associated with distraction osteogenesis have been extensively described, the exact changing of the surrounding tissues, such as nerve tissues, were still unclear. This study observed the histological changes and the expression of nerve growth factor (NGF) in the inferior alveolar nerve (IAN) after distraction osteogenesis. Unilateral mandibular distraction (0.5 mm twice per day for 10 days) was performed in eight mongrel dogs. Two animals were sacrificed at 7, 14, 28 and 56 days after completion of distraction, respectively. The distracted IAN and contralateral control nerve were harvested and processed for histological and innunohistochemical examinations. The signs of acute nerve injuries, such as demyelination and partial discontinuation of nerver fiber, were observed in the distracted IAN on 7 and 14 days after distraction. The initial remyelination and regeneration of distracted IAN were showed at 14 days after completion of distraction. At 56 days later, the histologic features of distracted IAN was similar to those of the normal control IAN. The expression of NGF was significantly increased in most distracted nerve tissues on 7, 14 and 28 days after distraction. On 56 days after distraction, the expression of NGF returned to the normal level. This study suggested that the acute IAN injury caused by mandibular distraction were mostly recovered during consolidation period. The NGF was seemed to be induced from Schwann cell and damaged nerve tissues, and it may have important roles in the initial healing of damaged nerves.