• Fibers and Polymers
• /
• 제6권3호
• /
• pp.181-185
• /
• 2005

Silk fibroin (SF) nanofibers were prepared by electrospinning and their application as an enzyme immobilization support was attempted. By varying the concentration of SF dope solution the diameter of SF nanofiber was controlled. The SF nanofiber web had high capacity of enzyme loading, which reached to $5.6\;wt\%$. The activity of immobilized a-chymotrypsin (CT) on SF nanofiber was 8 times higher than that on silk fiber and it increased as the fiber diameter decreased. Sample SF8 (ca. 205 nm fiber diameter) has excellent stability at $25^{\circ}C$ by retaining more than $90\%$ of initial activity after 24 hours, while sample SF11 (ca. 320 nm fiber diameter) shows higher stability in ethanol, retaining more than $45\%$ of initial activity. The formation of multipoint attachment between enzyme and support might increase the stability of enzyme. From these results, it is expected that the electrospun SF nanofibers can be used as an excellent support for enzyme immobilization.

• 한국환경보건학회지
• /
• 제30권5호
• /
• pp.358-365
• /
• 2004

The photocatalytic oxidation of Rhodamine B(RhB) was studied using photocatalytic reactor filled with module of quartz tube. Module of quartz tube consisted of small quartz tube (inner diameter, 1.5 mm; outer diameter, 3 mm) bundle coated with powder $TiO_2$ and uncoated large quartz tube (inner diameter, 20 mm; outer diameter, 22 mm). Two 30 W germicidal lamp was used as the light source and the reactor volume was 0.5 l. The effects of parameters such as the coating materials and numbers, initial concentration, $H_{2}O_2$ dose and metal deposition (Ag, Pt and Fe) and simultaneous application of $H_{2}O_2$ and metal deposition. The results showed that the initial reaction constant of quartz module coated with powder $TiO_2$ was higher 1.4 time than that of the $TiO_2$ sol and optimum coating number is twice. In order to increase reaction rate, simultaneous application of photocatalytic and photo-fenton reaction using Fe coating and dose $H_{2}O_2$ dose increased reaction rate largely.

• 소성∙가공
• /
• 제27권5호
• /
• pp.276-280
• /
• 2018

This paper has developed a forging process for conical shells for making aluminum cylindrical large shells. An incremental forging process was applied to reduce forging loads and die cost. The preform is designed based on the crosssectional area of the final forged shape. Inner diameter of the preform for mandrel forging is constant, and outer diameter is conical so that it matches the cross-sectional area of the product. However, simulation confirmed that the larger diameter is smaller than predicted and the length is larger than predicted because in the initial stage of forging, the large diameter portion first comes into contact with the anvil at the initial stage of forging and stretches in longitudinal direction. So, it has developed a rule to design the preform considering 3-D deformation instead of plane strain deformation at the beginning stage of mandrel forging. The developed mandrel forging process can be applied to more similar products and economic benefits may be obtained.

• 한국임상수의학회지
• /
• 제29권1호
• /
• pp.107-111
• /
• 2012

Three dogs (An 8 years-old intact female Poodle, a 7 years-old intact male Schunauzer, and an 8 yearsold Golden Retriever) were presented due to acute vomiting, dyspnea, and generalized weakness. Megaesophagus was confirmed through radiographic examination in all 3 dogs. Relative oesophageal diameter (ROD) was measured and results of ROD measurements showed the possibility of megaesophagus secondary to myasthenia gravis in three dogs. Thus we performed anticholinesterase test as screening test for myasthenia gravis. In all three dogs, esophageal diameter was reduced after neostigmine methylsulfate administration. For definite diagnosis of acquired myasthenia gravis, serum acetylcholine receptor antibody titer was measured, but definite diagnosis was confirmed only in one case. However, based on history, radiographic findings, anticholinesterase test, ROD measurement, other two cases were still suspected as megaesophagus secondary to myasthenia gravis. Treatment with pyridostigmine bromide was initiated in all dogs, and improvement of esophageal diameter was shown in all dogs. One dog was successfully managed for 15 months after initial treatment and, is still alive, but other two dogs were died shortly after initial treatment, because of severe aspiration pneumonia.

• Smart Structures and Systems
• /
• 제31권1호
• /
• pp.89-100
• /
• 2023

This paper conducts a parametric study of a new tuned mass damper with pre-strained superelastic SMA helical springs (SMAS-TMD) on the vibration reduction effect. First, a force-displacement relation model of superelastic SMA helical spring is presented based on the multilinear constitutive model of SMA material, and the tension tests of the six SMA springs fabricated are implemented to validate the mechanical model. Then, a dynamic model of a single floor steel frame with the SMAS-TMD damper is set up to simulate the seismic responses of the frame, which are testified by the shaking table tests. The wire diameter, initial coil diameter, number of coils and pre-strain length of SMA springs are extracted to investigate their influences on the seismic response reduction of the frame. The numerical and experimental results show that, under different earthquakes, when the wire diameter, initial coil diameter and number of coils are set to the appropriate values so that the initial elastic stiffness of the SMA spring is between 0.37 and 0.58 times of classic TMD stiffness, the maximum reduction ratios of the proposed damper can reach 40% as the mass ratio is 2.34%. Meanwhile, when the pre-strain length of SMA spring is in a suitable range, the SMAS-TMD damper can also achieve very good vibration reduction performance. The vibration reduction performance of the SMAS-TMD damper is generally equal to or better than that of the classic optimal TMD, and the proposed damper effectively suppresses the detuning phenomena that often occurs in the classic TMD.

• Journal of Korean Neurosurgical Society
• /
• 제62권2호
• /
• pp.256-262
• /
• 2019

Objective : Pituitary adenomas (PAs) are often detected as incidental findings. However, the natural history remains unclear. The objective of this study was to evaluate the natural history and growth pattern of untreated PAs. Methods : Between 2003 and 2014, 59 PAs were managed with clinico-radiological follow up for longer than 12 months without any kind of therapeutic intervention. Tumor volumes were calculated at initial and last follow-up visit, and tumor growth during the observation period was determined. Data were analyzed according to clinical and imaging characteristics. Results : The mean initial and last tumor volume and diameter were $1.83{\pm}2.97mL$ and $13.77{\pm}6.45mm$, $2.85{\pm}4.47mL$ and $15.75{\pm}8.08mm$, respectively. The mean annual tumor growth rate was $0.33{\pm}0.68mL/year$ during a mean observation period of $46.8{\pm}32.1months$. Sixteen (27%) PAs showed tumor growth. The initial tumor size (HR, 1.140; 95% confidence interval, 1.003-1.295; p=0.045) was the independent predictive factor that determined the tumor growth. Six patients (11%) of 56 conservatively managed non-symptomatic PAs underwent resection for aggravating visual symptoms with mean interval of 34.5 months from diagnosis. By Cox regression analysis, PAs of last longest diameter over 21.75 mm were a significant prognostic factor for eventual treatment. Conclusion : The initial tumor size of PAs was independently associated with the tumor growth. Six patients (11%) of conservatively managed PAs were likely to be treated eventually. PAs of last follow-up longest diameter over 21.75 mm were a significant prognostic factor for treatment. Further studies with a large series are required to determine treatment strategy.

• 소성∙가공
• /
• 제4권3호
• /
• pp.257-266
• /
• 1995

A simulation method based on upper bound method is developed in order to characterize forging characters in forging of spur gears. In this paper, utilizing a kinematically admissible velocity field and applying it to investigate the effect of inner diameter of holow billet. In the analysis, to predict the variation of inner diameter of hollw billet, neutral surface has been introduced. The neutral surface of each step is assumed as a circle and determined in order to have minimum forging energy by golden section method. By this method, the variation of inner diameter of billet during spur gear forging is successfully predicted. As a result, the selection of inner diameter of initial billet is very important to reduce the forging load.

• 한국공간정보시스템학회:학술대회논문집
• /
• 한국공간정보시스템학회 2004년도 춘계 학술발표회 논문집 제1권1호(통권1호)
• /
• pp.83-88
• /
• 2004

First author proposed a proportioning method for member sections of a single layer reticulated dome subjected to uniform and non-uniform load without any geometrical initial imperfection, and discussed the validity and effectiveness of the method which was based on linear buckling stress and a knock down factor. However, buckling of a single layer reticulated dome is strongly affected by initial imperfection. It is well known that geometrical initial imperfections reduce the nonlinear buckling capacity of a single layer raticulated dome. Thus, structural engineers may be recommended to reflect the effects of geometrical initial imperfections in proportioning member sections. In this paper, firstly, the presented proportioning method by first author is applied to dome without consideration of any imperfections and the thickness and diameter of each member are determined. Secondly, the load bearing capacities of the proportioned domes are checked with the imperfection, by the inelastic buckling analysis.

• 전기학회논문지P
• /
• 제65권4호
• /
• pp.262-267
• /
• 2016

This paper describes a design of a hair drier to improve its performance. the performance of the hair drier can be improved by increasing the wind velocity of its discharge port. the design of the hair drier is accomplished by using the CFD. the validity of design results were verified by comparison with the dry change of the hair drier. In this paper, the initial condition of the applied hair drier is as follows, the number of the blade is 9, the diameter of the suction port is 40[mm], the tip clearance is 12.5[mm], the con angle is $28.5^{\circ}$ and the fan angle is 27.5R. From design results, the enhanced condition of the hair drier can be obtained as follows, the number of the blade is 3, the diameter of the suction port is 50[mm], the tip clearance is 10.5[mm], the con angle is $21.5^{\circ}$ and the fan angle is 75R. At the enhanced condition of the hair drier, the wind velocity of the hair drier is 29[%] increase, and the dry time is 40[%] increase compare to the initial condition of the hair drier.

• 한국추진공학회:학술대회논문집
• /
• 한국추진공학회 2003년도 제20회 춘계학술대회 논문집
• /
• pp.87-90
• /
• 2003

압축성 유동장의 주된 특징은 유동장의 형성과정에 의존한다는 것은 잘 알려져 있다. 본 연구의 목적은 비평형 응축을 수반하는 초음속 제트유동장의 발달에 미치는 제트의 시간이력을 조사하는 것이다. 특히 초음속 습공기 제트에서 마하디스크 직경과 위치의 거동이 노즐압력비와 초기 상대습도의 항으로 소개된다. 대기흡입식 풍동설비에 장착된 노즐의 출구에서 부족팽창된 습공기 제트를 얻기 위해 노즐의 압력비와 초기상대습도를 변화시켰다. 마하디스크의 직경은 동일한 압력비에서 상대습도가 증가함에 따라 증가하지만, 그 위치는 상류로 이동하는 것으로 나타났다. 또한 노즐의 작동압력비가 증가하는 경우의 마하디스크 직경과 발생위치가 감소하는 경우보다 더 크다.