• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.25 no.4
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• pp.304-310
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• 1999

This study was designed to find the effect of Minocycline loaded microcapsule applied locally to tissue by measuring drug concentration in tissue and serum by HPLC and to achieve optimal drug delivery system and duration to a specific target site. Control group were administrated minocycline intramuscularly twice a day with $0.2{\mu}g/100g$ for 1 to 10 days. In experimental group, surgical wound was created on Rt. cheek and then minocycline loaded microcapsule was applied into the space between superficial and deep layer of masseter muscle. Animals were sacrificed at 1, 3, 5, 7, 10 days after initial administration, blood was obtained from heart and right masseter muscle was excised. Blood sample was centrifuged at 3000rpm for 15min. Tissue sample was homogenized, left at room temperature for 48hr and centrifuged at 4000g for 5min. Supernatant was completely dried and dissolved in distilled water. Analysis was conducted using a ${\mu}Bondapack$ C18 column. The mobile phase was 0.2M Ammonium Oxalate/0.1M EDTA/DMF=11/4/5 solution, which was injected into the column and detected with photodiode detector at 344nm wavelength. The results were as follows : 1. This method was reliable, could be replicated and suitable for minocycline analysis in tissue as well as serum. 2. In tissue, concentration of minocycline of experimental group was higher than that of control group for 5days. 3. Except 1 day, concentration of minocycline in serum of experimental group was lower than that of control group. 4. Concentration of minocycline in tissue was much higher than that in serum. From these results, minocycline loaded microcapsule might be effective tool for local drug delivery system might be useful for treatment of infections of oral and maxillofacial region and management of infected surgical wound, minimizing systemic effects.

• Clinics in Shoulder and Elbow
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• v.2 no.1
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• pp.53-59
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• 1999

Initial treatment of multidirectional instability of the shoulder would be a thorough rehabilitation program. If rehabilitation fails to resolve a patient's symptoms, the most commonly performed surgical procedure remains the inferior capsular shift. Eleven patients who had disabling multidirectional instability of the shoulder were managed with the inferior capsular shift. All of the procedure were performed by means of an anterior approach and a laterally based capsular shift. All of the patients were the contact athletes. The purpose of our study was to evaluate the efficacy of the inferior capsular shift procedure in the contact athletic patients, to review the loss of external rotation postoperatively and to discuss their return to sports. Mean follow up duration was 14.5 months(range, 12 to 24). Pain was relieved postoperatively in all cases and most patients could get stability except one case of recurrent subluxation. The average loss of external rotation and forward flexion after the operation were Y and 30 at last follow up. By the rating scale from American Shoulder and Elbow Society, overall scores improved from 49 points to 85 points. The results were excellent or good in 9 patients(82%) out of 11 patients. In reference to return to sports, 10 patients(91 %) of 11 patients returned to their sports with 7 patients (64%) returning at the same levels of competitiveness. The inferior capsular shift procedure was considered to be a recommendable method for the management of the multidirectional instability of the shoulder.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.2
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• pp.147-152
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• 2015

We designed, fabricated, and tested the capacitive microsensors for skin piloerection monitoring. The performance of the skin piloerection monitoring sensor was characterized using the artificial bump, representing human skin goosebump; thus, resulting in the sensitivity of $-0.00252%/{\mu}m$ and the nonlinearity of 25.9 % for the artificial goosebump deformation in the range of $0{\sim}326{\mu}m$. We also verified two successive human skin piloerection having 3.5 s duration on the subject's dorsal forearms, thus resulting in the capacitance change of -6.2 fF and -9.2 fF compared to the initial condition, corresponding to the piloerection intensity of $145{\mu}m$ and $194{\mu}m$, respectively. It was demonstrated experimentally that the proposed sensor is capable to measure the human skin piloerection objectively and quantitatively, thereby suggesting the quantitative evaluation method of the qualitative human emotional state for cognitive human-machine interfaces applications.

• Journal of Korean Neurosurgical Society
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• v.29 no.1
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• pp.66-71
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• 2000

Objective : There are many treatment modalitis in management of idiopathic trigeminal neuralgia. In the secondary trigeminal neuralgia, there has been only sporadic reports of the etiology. Authors report the treatment result of secondary trigeminal neuralgia with percutaneous radiofrequency rhizotomy. Methods : During last ten years, 129 trigeminal neuralgias were treated by percutaneous radiofrequency(RF) rhizotomy by authors. Among them, nine patients were secondary trigeminal neuralgias. These patients refused treatment for the primary cause and only wanted pain control. The offending lesions were three arachnoid cysts, six tumors. The mean age was 47.8 years and the mean duration of follow-up was 6.2 years. The right V2,3 distribution was most prevalent area of pain. Authors used the conventional Hartel's anterior approach and straight electrode for RF lesion generation. Result : The early result was satisfactory. Eight of nine patients became free of pain and one patient needed minimal dose of carbamazepine. The overall pain control was 100%. There was no mortality or morbidity for initial RF rhizotomy. During follow-up, four patients showed recurrence of pain(44%). Among these, two underwent repeated RF rhizotomy and became free of pain. The other two were controlled with medical management. Conclusion : These results indicate that the percutaneous RF rhizotomy is effective means of pain control. Overall recurrence was somewhat higher than that of idiopathic trigeminal neuralgia. Even with recurrence, however, repeated RF rhizotomy seems to be effective method of control of pain in these cases.

• Journal of the Korean GEO-environmental Society
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• v.16 no.4
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• pp.23-32
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• 2015

This paper addresses the effects of extreme rainfall on the stability of cut slopes in Yen Bai city, Northern Viet Nam. In this area, natural slopes are excavated to create places for infrastructures and buildings. Cut slopes are usually made without proper site investigations; the design is mostly based on experience. In recent years, many slope failures have occurred along these cuts especially in rainy seasons, resulting in properties damaged and loss of lives. To explain the reason that slope failure often happens during rainy seasons, this research analyzed the influence of extreme rainfalls, initial ground conditions, and soil permeability on the changes of pore water pressure within the typical slope, thereafter determining the impact of these changes on the slope stability factor of safety. The extreme rainfalls were selected based on all of the rainfalls triggering landslide events that have occurred over the period from 1960 to 2009. The factor of safety (FS) was calculated using Bishop's simplified method. The results show that when the maximum infiltration capacity of the slope top soil is less than the rainfall intensity, slope failures may occur 14 hours after the rain starts. And when this happens, the rainfall duration is the deciding factor that affects the slope FS values. In short, cut slopes in Yen Bai may be stable in normal conditions after the excavation, but under the influence of tropical rain storms, their stability is always questionable.

• Clinics in Shoulder and Elbow
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• v.8 no.1
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• pp.19-22
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• 2005

Purpose: The causes of twelve cases of the mid-shaft clavicle nonunion and the results of internal fixation with plate and bone graft were investigated. Materials and method: From August 1997 to March 2003, twelve cases of the mid-shaft clavicle nonunion were operated with internal fixation with plate and bone graft. The duration of follow-up was average 13 months. Results: The causes of the mid-shaft clavicle nonunion included severe associated injury, severe initial displacement of the fracture fragments and insecure fixation. All cases were operated with internal fixation with plate and bone graft. According to the factor for evaluations of results, using a rating scale of excellent (no apparent factors), good (one factor), fair (two factors), poor (more than three factors), the results showed 10 excellent, 1 good and 1 poor. Screw loosening was developed in only one case . Conclusion: The internal fixation with plate and bone graft of the mid-shaft clavicle nonunion after failed conservative treatment achieved excellent results and seemed to be the procedure of choice for mid-shaft clavicle nonunion.

• The Journal of the Korean bone and joint tumor society
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• v.4 no.2
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• pp.81-87
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• 1998

Although autoclaved autogenous bone reconstruction is one of the established procedures, it may have some problems in bone regeneration and mechanical property. The purpose of this study is to evaluate the efficacy of more biologic and anatomical reconstruction where allograft is not readily available. From Aug.1991 to Feb. 1996 the authors analyzed 32 cases of reconstruction with autogenous low heat treated bone. Autogenous graft sites were humerus 4, tibia 4, pelvis 9, and 15 femur. Average follow-up period was 23(range;12-51) months. There were 49 graft-host junctional sites. Diaphysis was 22, metaphysis 10, and flat bone 17. Average duration of healing for the 38 united sites was 7 months. Average union time for each anatomical area 8 months in 19 diaphysis, 12 months in 7 metaphysis, and 12.7 months in 12 flat bone(pelvis). Eleven nonunion sites consisted of 3 diaphysis(3/22), 3 metaphysis(3/10), and 5 flat bone(5/17). Complications other than nonunion were local recurrence(4), bone resorption(3), graft fracture(2), osteomyelitis(1), metal failure(2), and wound infection(1). Initial bone quality and stable fixation technique was important for union rate. Plate and screw is a good method for diaphyseal lesion. Metaphyseal and flat bone are weak area for rigid fixation and one stage augmentation with iliac bone graft can be a salvage procedure.

• Journal of Environmental Science International
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• v.19 no.6
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• pp.747-753
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• 2010

It follows in quality and sewage exclusion method of the investigation objective sector and the Combined Sewer Overflows which is suitable in regional characteristics and the confluence area against the rainfall initially a flow and the medulla and measurement - it analyzes the initial rainfall outflow possibility control plan which is suitable in the domestic actual condition and it proposes the monitor ring plan for the long-term flow and pollution load data accumulation. From the research which it sees the Infiltration water/Influent water and CSOs investigation it passes by the phase of hazard chain and Namwon right time 4 it does not hold reverse under selecting, Measurement it used the hazard automatic flow joint seal Sigma 910 machine and in case 15 minute interval of the I/I, it measured a flow at case 5, 15 minute standing of the CSOs. The water quality investigation for the water leakage investigation of the I/I and the sewage from the point which is identical with flow measurement during on-the-spot inspection duration against 6 items which include the BOD sampling and an analysis, when the rainfall analysis for CSOs fundamental investigation analyzed against 18 items which include the BOD sampling. Consequently, for the optimum interpretation invasion water / inflow water of the this investigation area day average the lowest flow - water quality assessment veterinarian optimum interpretation hazard average per day - lowest flow - it averages a medulla evaluation law department one lowest flow evaluation technique and it selects, it presentation collectively from here it gets, position result with base flow analysis of invasion water / inflow water.

• Journal of agricultural medicine and community health
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• v.6 no.1
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• pp.73-81
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• 1981

This study was designed to analyze the result of Tb worker's activities on the performance of follow up program as part of the government tuberculosis program. The specific objectives of this study was also to improve the method of managing the patient who were registered at health center by the setting the priorities depend upon in their results of sputum examination and X-ray examination. All the medical records of 509 patients who were dropped out from government health center in Kyongnam area during 1978, were analyzed and interpreted. Followings are the result of the study. 1. The number of investigated cases were 509 (356% males and 153 females), by age the most prevalent group was 20~29 year old group as 27.3% and 20~40 year old group was 61.5%, above 61 year old was 14.9%. 2. The microscopic result of their sputum was positive in 52.1%, and by X-ray examination moderate advanced case was 63.9% minimal 18.5% and far advanced 17.6% in order. 3. Average duration of treatment was 9.03 months, 11.4 months in microscopic positive cases and 6.5 months in negative cases. 4. Conversion rate of microscopic positive case was 42.9% on sputum culture, in the negative cases, it was confirmed in negative 20.1% only by the initial sputum culture. 5. The rate who get take X-ray and sputum examination among any family member of the patients was 43.4% in positive cases, 20.9% in negative cases. 6. 80.2% of positive cases took X-ray for following up in every 6 month after registration, 41.0% in negative cases. 7. Defaulting reasons which recorded in individual card were undetermined reason (42.0%), treating elswhere (22. 4%), refused treatment (17.9%) and moved out (17.7%).

• Journal of the Korean Society of Environmental Restoration Technology
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• v.25 no.3
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• pp.97-111
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• 2022

This study was conducted as restoration work to improve the discharge in forested wetlands where there is a concern of damage and observed changes in the discharge and groundwater level. The monthly changes showed that during the wet season, the amount of discharge decreased after restoration and GWL increased. It showed that during the dry season, the GWL and discharge increased. The increased discharge after restoration seems to be the difference in the number of days with no rainfall duration. The change in discharge for each unit of rainfall showed a tendency to increase the baseflow and decrease the direct discharge after restoration. The recharge ratio of GWL showed a decreasing tendency as rainfall was higher. After restoration, it showed a higher tendency under rainfall with less than 20mm. It has been confirmed that the restoration implemented by the study caused such an effect as the increased baseflow and increased GWL. It would be an effective restoration method to maintain water resources in forested wetlands. In the initial rainfall, it demonstrated a certain level of effect, but it is necessary to develop a restoration technology that can decrease the amount of water discharged after the end of rainfall or during the period of no rainfall to protect and maintain the forested wetlands. Streamflow should be identified by each type of terrain of wetlands and a proper restoration countermeasure should be devised for the site where the discharge frequently occurs.