• Title/Summary/Keyword: Ingestion dose

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A Study on the Assessment of Derived Intervention Levels in Foodstuffs Using the Dynamic Ingestion Pathway Model (동적 섭식경로모델을 이용한 음식물에 대한 유도 방사능 개입준위의 산정에 관한 연구)

  • Hwang, Won-Tae;Han, Moon-Hee;Kim, Byung-Woo
    • Journal of Radiation Protection and Research
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    • v.19 no.3
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    • pp.199-208
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    • 1994
  • The derived intervention levels in Korean foodstuffs were estimated using the dynamic ingestion pathway model which was developed considering Korean environment. The derived intervention levels were estimated from the intervention level of dose based on the thyroid committed dose equivalent of infant in the case of I-131, and the whole body committed dose equivalent for age groups and 13 kinds foodstuffs in the cases of Cs-137 and Sr-90. The derived intervention levels were shown as a considerable variation with deposition time and radionuclide. The adult was the most important age group in the estimation of derived intervention levels for Cs-137 and Sr-90. In the adult, the derived intervention levels for rice were 2390 and 47 Bq/kg for Cs-137 and Sr-90 in the case of deposition in summer, respectively, and 198 and 79 Bq/kg in the case of deposition in winter, respectively.

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Ingestion Toxicity of Fipronil on Reticulitermes speratus kyushuensis (Isoptera: Rhinotermitidae) and Its Applicability as A Termite Bait

  • Kim, Si Hyun;Chung, Yong Jae
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.2
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    • pp.159-167
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    • 2017
  • Historical wooden buildings in Korea are being damaged by Reticulitermes speratus kyushuensis Morimoto, a type of subterranean termite, and the scale of this damage is increasing gradually because of global warming. This study evaluated the ingestion toxicity of the phenylpyrazole insecticide fipronil to R. s. kyushuensis and its applicability as termite bait with the aim of controlling termite colonies more efficiently. An ingestion toxicity assessment was conducted and the $LT_{50}$ was determined to be 4.43 day at concentrations of 10 ppm, indicating a slow-acting effect; therefore, 10 ppm was selected as an appropriate dose. A field applicability assessment was conducted in which the number of foraging workers and the rate at which the termites fed decreased 2 weeks after baiting, and termite colony activity was no longer apparent after 4 weeks demonstrating the efficacy of fipronil at eliminating colonies. Taken together, these results, indicate that low-dose fipronil eliminated R. s. kyushuensis colonies faster than insect growth regulators; therefore, it is expected to be useful when trying to conserve historical wooden buildings.

Comparative Analysis of Effective Dose Evaluation forTritium in Animal Product Ingestion According to Domestic and International Evaluation Methodologies Using Data from the Republic of Korea (대한민국의 데이터를 활용한 국내·외 평가 방법론에 따른 축산물 취식 시 삼중수소 유효선량 평가 비교·분석)

  • JeWan Park;YongMin Kim
    • Journal of Radiation Industry
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    • v.17 no.4
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    • pp.437-442
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    • 2023
  • This study conducted a comparative analysis of dose evaluations for ingestion of animal products based on data from nuclear power plants in the Republic of Korea, using methodologies from the Republic of Korea, 'IAEA TRS-472', and 'CSA N288.1:14'. The research focused on tritium, the most significant constituent among the gaseous and liquid radioactive emissions. The combined evaluation of tritium, in the form of tritiated water (HTO) and organically bound tritium (OBT), yielded results of 1.143 μSv y-1 for the Republic of Korea, 0.965μSv y-1 for 'TRS-472', and 0.886μSv y-1 for 'N288.1:14'. Despite the Republic of Korea's guidelines not considering OBT, the evaluation results for the Republic of Korea were higher compared to other methodologies. This discrepancy was attributed to the unique approach of not considering the moisture content per individual in the calculations of plant and feed concentration in the Republic of Korea and the simultaneous consideration of specific-activity model and transfer model. The study highlights the necessity of developing dose evaluation models tailored to regional characteristics and underscores the importance of including OBT in these evaluations.

Effect of Osmolality on the Absorption of Ethanol in the Rabbit (삼투질농도가 Ethanol 흡수(吸收)에 미치는 효과)

  • Kim, Shin-Yoon;Kim, Byoung-Guk;Yoo, Kyoung-Mu;Kim, Hyeong-Jin;Park, Jae-Sik;Hwang, Soo-Kwan
    • The Korean Journal of Physiology
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    • v.15 no.1
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    • pp.53-59
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    • 1981
  • In the present study, an effort was directed to elucidate the effect of osmolality on the absorption of ethanol in rabbits. A single dose of 13.67 ml(2. 16 gm ethanol/kg BW) of hypo-, iso-hyphen and hypertonic ethanol per kg BW was administered into the stomach to albino rabbits and the experiment was performed at 30 th, 60 th and 120 th minute. The blood ethanol level was determined by the method of Williams et al, and hematocrit(Hct) was determined by the conventional Hct centrifuge and reader. The results are summarized as follow. The blood ethanol level showed the highest value at 60 min after the ethanol ingestion in the hypo- and isotonic groups, $171.3{\pm}13.3\;mg%$ and $204.5{\pm}23.0\;mg%$, respectively, but in the hypertonic group, the highest value was observed at 120min after the ingestion. The absorption rate of ethanol between 0 to 30 min after the ingestion of hypo- and isotonic ethanol was $88.54{\pm}12.04$ and $94.73{\pm}8.33\;mg/min$, respectively, but a decreased value of $44.72{\pm}6.69\;mg/min$ was noted after hypertonic ethanol ingestion comparing with hypo- and isotonic groups, The Hct value after hypo- and isotonic ethanol ingestion was decreased at 30 min but returned to the control level at 120 min. In contrast with hypo- and isotonic ethanol ingestion, hypertonic ethanol ingestion produced an increase of the Hct value at 30 min and returned to the control level at 120 min. The heart rate was increased but the respiratory rate was decreased after ethanol ingestion regardless of the osmolality.

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Evaluation of Cut-off Values in Acute Acetaminophen Intoxication Following the Revised Guideline of the United Kingdom (개정된 가이드라인에 따른 아세트아미노펜 급성 중독환자 치료 기준의 검증)

  • Park, Sung Jin;Cha, Kyungman;So, Byung Hak;Kim, Hyung Min;Jeoung, Won Jung
    • Journal of The Korean Society of Clinical Toxicology
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    • v.16 no.2
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    • pp.68-74
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    • 2018
  • Purpose: In 2012, a revised guideline for acute acetaminophen overdose was proposed in the UK, recommending that the treatment threshold should be lowered to 100 mcg/ml at 4 hours after ingestion without risk stratification of hepatotoxicity. However, the poison centers in some developing countries do not have laboratory resources to provide serum drug levels in time. The primary aim of the study is to evaluate the cut-off value of reported dose per kilogram to determine when N-acetylcysteine treatment is warranted under the revised guideline. Methods: Data were collected retrospectively from the toxicology registry of an urban emergency medical center between 1st January 2010 and 30th June 2017. Inclusion criteria were single acute overdose of more than 75 mg/kg in 15 hours from ingestion and over 14 years of age. Subgroups were created by 25 mg/kg increments of reported dose, then sensitivity, specificity, positive predictive value and negative predictive value were calculated for the cut-off values of 100 mg/kg, 125 mg/kg, 150 mg/kg and 175 mg/kg for toxic serum level over '100-treatment line'. Results: A total of 99 patients were enrolled in the study; 24 patients showed toxic serum levels (24.2%). Zero of 17 patients with an ingestion dose under 100 mg/kg showed toxic level (0%), and 0 of 15 under 125 mg/kg (0%), 2 of 14 under 150 mg/kg (14.3%), and 4 of 12 under 175 mg/kg (33.3%) had toxic levels. The higher the ingested dose per kilogram of weight, the higher the frequency of the toxic serum concentration on the first test (${\chi}^2$ test for trend, ${\chi}^2=22.66$, p-value<0.001) and the sensitivity of each value was 100%, 100%, 92% and 76%. Conclusion: In acute single acetaminophen intoxication, the ingestion dose of 100 mg/kg of weight will be useful in determining the need for the N-acetylcysteine antidote in the indigent laboratory environment.

A Study on the Application of Countermeasure for the Reduction of the Ingestion Dose After Nuclear Accidents

  • Hwang, Won-Tae;Suh, Kyung-Suk;Kim, Eun-Han;Park, Young-Gil;Han, Moon-Hee;Gyuseong Cho
    • Proceedings of the Korean Nuclear Society Conference
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    • 1998.05b
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    • pp.583-588
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    • 1998
  • The effectiveness of dose reduction resulting from the application of countermeasures for ingestion pathways after nuclear accidents was investigated together with the derivation of optimized intervention levels for Korean foodstuffs. The radioactivity in foodstuffs was predicted from a dynamic food chain model DYNACON for the date which the deposition occurs. The effectiveness of countermeasures strongly depended on radionuclides, foodstuffs and date of deposition.

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Parameter Uncertainty and Sensitivity Analysis on a Dose Calculation Model for Terrestrial Food-Chain Pathway (육상식품 섭취경로에 의한 선량계산 모델에서 파라메터의 불확실성 및 민감도 분석)

  • Lee, Chang-Woo;Choi, Yong-Ho;Chun, Ki-Jung;Lee, Jeong-Ho
    • Journal of Radiation Protection and Research
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    • v.16 no.2
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    • pp.67-74
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    • 1991
  • Parameter uncertainty and sensitivity of KFOOD model for calculating the ingestion dose via terrestrial food-chain pathway was analyzed with using Monte-Carlo approach. For the rice ingestion pathway, estimated values from KFOOD code were very conservative. Most sensitive input parameters in model were deposition velocities and soil-to-plant transfer coefficient of radionuclides.

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Radiological Safety Assessment for a Near-Surface Disposal Facility Using RESRAD-ONSITE Code

  • Jang, Jiseon;Kim, Tae-Man;Cho, Chun-Hyung;Lee, Dae Sung
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.19 no.1
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    • pp.123-132
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    • 2021
  • Radiological impact analyses were carried out for a near-surface radioactive waste repository at Gyeongju in South Korea. The RESRAD-ONSITE code was applied for the estimation of maximum exposure doses by considering various exposure pathways based on a land area of 2,500 ㎡ with a 0.15 m thick contamination zone. Typical influencing input parameters such as shield depth, shield materials' density, and shield erosion rate were examined for a sensitivity analysis. Then both residential farmer and industrial worker scenarios were used for the estimation of maximum exposure doses depending on exposure duration. The radiation dose evaluation results showed that 60Co, 137Cs, and 63Ni were major contributors to the total exposure dose compared with other radionuclides. Furthermore, the total exposure dose from ingestion (plant, meat, and milk) of the contaminated plants was more significant than those assessed for inhalation, with maximum values of 5.5×10-4 mSv·yr-1 for the plant ingestion. Thus the results of this study can be applied for determining near-surface radioactive waste repository conditions and providing quantitative analysis methods using RESRAD-ONSITE code for the safety assessment of disposing radioactive materials including decommissioning wastes to protect human health and the environment.

Analysis of Domestic and Overseas Radioactive Waste Maritime Transportation and Dose Assessment for the Public by Sinking Accident (국내·외 방사성폐기물 해상운반 현황 및 침몰사고 시 일반인 선량평가 사례 분석)

  • Ga Eun Oh;Min Woo Kwak;Hyeok Jae Kim;Kwang Pyo Kim
    • Journal of Radiation Industry
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    • v.18 no.1
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    • pp.35-42
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    • 2024
  • Demand for RW transportation is expected to increase due to the continuous generation of RW from nuclear power plants and facilities, decommissioning of plants, and saturation of spent fuel temporary storage facilities. The locational aspect of plants and radiation protection optimization for the public have led to an increasing demand for maritime transportation, necessitating to apprehend the overseas and domestic current status. Given the potential long-term radiological impact on the public in the event of a sinking accident, a pre-transportation exposure assessment is necessary. The objective of this study is to investigate the overseas and domestic RW maritime transportation current status and overseas dose assessment cases for the public in sinking accident. Selected countries, including Japan, UK, Sweden, and Korea, were examined for transport cases, Japan and the U.S were chosen for dose assessment case in sinking accidents. As a result of the maritime transportation case analysis, it was performed between nuclear power plants and reprocessing facilities, from plants to disposal or intermediate storage facilities. HLW and MOX fuel were transported using INF 3 shipments, and all transports were performed low speed of 13 kn or less. As a result of the dose assessment for the public in sinking accident, japan conducted an assessment for the sinking of spent fuel and vitrified HLW, and the U.S conducted for the sinking of spent fuel. Both countries considered external exposure through swimming and working at seashore, and internal exposure through seafood ingestion as exposure pathway. Additionally, Japan considered external exposure through working on board and fishing, and the U.S considered internal exposure through spray inhalation and desalinized water and salt ingestion. Internal exposure through seafood ingestion had the largest dose contribution. The average public exposure dose was 20 years after the sinking, 0.04 mSv yr-1 for spent fuel and 5 years after the sinking, 0.03 mSv yr-1 for vitrified HLW in Japan. In the U.S, it was 1.81 mSv yr-1 5 years after the sinking of spent fuel. The results of this study will be used as fundamental data for maritime transportation of domestic RW in the future.