• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권2호
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• pp.83-88
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• 2009

The purpose of this epidemiologic study was to provide clinically useful information on the fundamentals for both the diagnosis and treatment planning of oral squamous cell carcinoma, which comprises $80{\sim}90%$ of all oral cancers. One hundred and forty two patients diagnosed with oral squamous cell carcinoma were selected from a total of 220 patients with oral malignancies. The patients' medical and follow-up records were reviewed and their survival was traced. The highest occurrence rate was observed in those aged between 60 and 69 years. The tongue was the most common primary site(31.7%) for oral squamous cell carcinoma. The survival rate was calculated using the Kaplan-Meier method. The overall five-year survival rate of oral squamous cell carcinoma patients was 66.90%. The 5-year survival rate according to stage was 85.82% for stage I, and 49.98% for stage IV. The five-year survival rate according to the originating site was 91.67% for the retromolar trigone, 75.30% for the tongue, and 62.41% for the maxillary gingiva. In terms of cell differentiation, the majority(58.5%) was the well-differentiated type, which had a 5-year survival rate of 70.62%.

• Journal of Communications and Networks
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• 제6권3호
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• pp.269-279
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• 2004

A new online multi-layer integrated routing (MLIR) scheme that combines IP (electrical) layer routing with WDM (optical) layer routing is investigated. It is a highly efficient and cost-effective routing scheme viable for the next generation integrated optical Internet. A new simplified weighted graph model for the integrated optical Internet consisted of optical routers with multi-granularity optical-electrical hybrid switching capability is firstly proposed. Then, based on the proposed graph model, we develop an online integrated routing scheme called differentiated weighted fair algorithm (DWFA) employing adaptive admission control (routing) strategies with the motivation of service/bandwidth differentiation, which can jointly solve multi-layer routing problem by simply applying the minimal weighted path computation algorithm. The major objective of DWFA is fourfold: 1) Quality of service (QoS) routing for traffic requests with various priorities; 2) blocking fairness for traffic requests with various bandwidth granularities; 3) adaptive routing according to the policy parameters from service provider; 4) lower computational complexity. Simulation results show that DWFA performs better than traditional overlay routing schemes such as optical-first-routing (OFR) and electrical-first-routing (EFR), in terms of traffic blocking ratio, traffic blocking fairness, average traffic logical hop counts, and global network resource utilization. It has been proved that the DWFA is a simple, comprehensive, and practical scheme of integrated routing in optical Internet for service providers.

• 대한지리학회지
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• 제47권6호
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• pp.884-898
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• 2012

지명에는 해당 지역과 그 지역주민들의 삶에 관한 정보들이 녹아 있다. 특히, 오래전부터 이어져 온 고지명은 더 많은 공간적 속성들을 포함한다. 본 연구에서는 전통 지명의 하나인 고지명 '두모'를 연구대상으로 하여 그 분포와 특성을 고찰하였다. '두모'는 Nam(1996)에 의해 연구되기 시작한 지명군으로, 어원적 의미를 살펴본 결과 지명 자체에 산이나 물과 연관된 지형적 입지 조건의 의미를 내포하고 있었다. 그리고 전국에 걸쳐 비교적 균등하게 분포하는 가운데, 85%가 인문지명으로 사용되고 있었고 그중에 73%는 취락명이나 행정구역명 등 취락지명이 차지하고 있었다. 본 연구에서는 두모계 지명의 마을 220개만을 가지고 두모계 취락의 입지와 지명의 확산을 심층 분석하였다. 그 결과, 두모계 취락이 주로 남 동향을 취하고 배산임수의 지형적 조건을 갖추고 있었으며, 마을의 확장에 따라 두모계 지명이 분화되면서 여러 개의 두모계 지명이 함께 분포하고 있음을 확인하였다.

• 한국수산과학회지
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• 제51권1호
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• pp.79-90
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• 2018

Fish ages are critical information in fish stock assessments because they are required for age-structure models such as virtual population analysis and stochastic catch-at-age models, whose outputs include recruitment strengths, a spawning stock size (abundance or biomass), and the projection of a fish population size in future. However, most countries other than the developed countries have not identified ages of fish caught by fisheries or surveys in a consistent manner for a long time (e.g.,>20 years). Instead, data about fish body sizes (e.g., lengths) have been well available because of ease of measurement. To infer age compositions of fish in a target group using fish length data, we intended to improve the length frequency analysis (LFA), which Schnute and Fournier had introduced in 1980. Our study was different in two ways from the Schnute and Fournier's method. First we calculated not only point estimates of age compositions but also the uncertainty in those estimates. Second, we modified LFA based on the von Bertalanffy growth model (vB-based model) to allow both individual-to-individual and cohort-to-cohort variability in estimates of parameters in the vB-based model. For illustration, we used data about lengths of Korean mackerel Scomber japonicas caught by purse-seine fisheries from 2000-2016.

• 한국가금학회지
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• 제44권3호
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• pp.199-209
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• 2017

Mitogen-activated protein kinase (MAPK) signaling pathways play a key role in innate immunity, inflammation, cell proliferation, cell differentiation, and cell death. The main objective of this study was to investigate the expression level of candidate MAPK pathway genes in the intestinal mucosal layer of two genetically disparate chicken lines (Marek's disease-resistant line 6.3 and Marek's disease-susceptible line 7.2) induced with necrotic enteritis (NE). Using high-throughput RNA sequencing, we investigated 178 MAPK signaling pathway related genes that were significantly and differentially expressed between the intestinal mucosal layers of the NE-afflicted and control chickens. In total, 15 MAPK pathway genes were further measured by quantitative real-time PCR(qRT-PCR) and the results were consistent with the RNA-sequencing data. All 178 identified genes were annotated through Gene Ontology and mapped onto the KEGG chicken MAPK signaling pathway. Several key genes of the MAPK pathway, ERK1/2, JNK1-3, p38 MAPK, MAP2K1-4, $NF-{\kappa}B1/2$, c-Fos, AP-1, Jun-D, and Jun, were differentially expressed in the two chicken lines. Therefore, we believe that RNA sequencing and qRT-PCR analysis provide resourceful information for future studies on MAPK signaling of genetically disparate chicken lines in response to pathogens.

• 동의생리병리학회지
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• 제30권2호
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• pp.124-130
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• 2016

The aim of this study was to suggest the future direction of diagnostic and evaluative pattern identification questionnaire (PIQ) by reviewing the state of development and utilization of PIQ according to Korean classification of disease-U (KCD-U). We surveyed the database of OASIS, NDSL, KISS, DBPIA, and Pub-med to know the kinds of developed and developing PIQ of Korean medicine. We used 'Pattern Identification' and 'Questionnaire' to find suitable papers. The inclusion criteria met 47 cases. The number of PIQ before 2000yrs, between 2001 to 2005, 2006-2010, 2011-2015 were 2, 5, 18, 22cases. The number of PIQ belonged to the disease of Korean medicine, the pathological symptom of korean medicine, the Sasang constitutional pattern identification and etc according to KCD-U were 20(42.6%), 8(17%), 9(19.1%) and 10(21.3%). Twenties among forty seven PIQ were validated, and the rest of them were not validated. The distribution of the numbers of PIQ were significantly different according to KCD-U (p=0.003). The direction of Utilization of PIQ was 36 questionnaires in diagnosing PI, 14 cases in evaluating health state, 4cases in evaluating effects of a treatment and 8 ones in diagnosing Sasang constitutional types. This study reveals the status on validated and non-validated PIQ of Korean medicine and suggests the basic information for the direction of developing PIQ in the future.

• 한국유기농업학회지
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• 제11권2호
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• pp.23-42
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• 2003

The study must have standpoints for the stable market construction of the Environmental-Friendly agricultural products of the quality-certificated which has rapidly grown due to a discussion of the environment and agriculture, income increase and the interests on foods stability. The survey was conducted through face-to-face interview of 200 adults who are in their twenties or more in Cheonan-city. In this research, the Environmental-Friendly agriculture was a clean agriculture not using a fertilizer or chemicals and the agriculture which protects the environment by preventing the environmental pollution. In the analyses of the consumer's willingness to pay, the rice showed 69,851 won, and a lettuce and bean-curd showed 947 won and 1.412 won respectively. In terms of current issues of the policy, to establish the stable circulation structure and consumption strategy, there must be a clearness raise of the Quality Authentication (QA) Mark. To raise the trust through quality authentication, there must be transparency raise of information by distribution stages and the thorough post management of the official institutes. Also, to persue the competitive product differentiation, there must be the settlement of the product brand on the market, development of the new production technology and a classification of consumers by incomes. Finally to construct stable distribution and price system, there must be active participation of the local agricultural cooperatives in the distribution of the Environmental-Friendly agricultural products of the quality-certificated and the understanding of the proper price of the consumer market and flexible strategy of the price change.

• 대한유전성대사질환학회지
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• 제15권3호
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• pp.110-117
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• 2015

All infants should be screened for phenylketonuria (PKU) within the three days of life, in order to allow timely dietary intervention to protect children with PKU from neurologic damage in Korea. A commonly used cut-off level for diagnosis of PKU is $240{\mu}mol/L$ (4 mg/dL). Up to 2% of cases of hyperphenylalaninemias (HPA) detected by the screening test will account for a disorder of $BH_4$ metabolism. Therefore, analysis of blood or urinary pterins is essential, backed up with measurement of DHPR activity, as this allows differentiation of $BH_4$ disorders. A $BH_4$ loading test and measurement of neurotransmitters in CSF provide further important information to the severity of $BH_4$ deficiency and $BH_4$ loading test can detect patients with $BH_4$ deficiency and $BH_4$ responsive PKU. Several protocols for $BH_4$ loading test have been described, involving treatment with $BH_4$ for periods ranging from 1 day to 1 month, and using doses of $BH_4$ of 10-20 mg/kg. There is general agreement that a reduction on blood phenylalanine of at least 30% in response to $BH_4$ loading indicates a clinically significant effect, although in some tests a lower cut-off value may be defined for individual patients, or no specific cut-off value is proposed. The frequency of $BH_4$ responsiveness is highest in patients with mild HPA and mild to moderate PKU resulting from PAH mutations with residual activity.

• 한국의류학회지
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• 제27권9_10호
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• pp.1081-1092
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• 2003

The purpose of this study was to identify the current situation of textiles and apparel firms in the overseas markets and to examine the relationship between firms' characteristic(i.e., sales volume) and international marketing strategies. A random sample of 311 textiles and apparel firms were selected. The survey design method was used to test conceptual framework. Adjusted response rate was 33.4%(n=115). Descriptive analysis (i.e., frequency, percent) and $\chi$$^2$-test were used for data analysis. About the current situation of textiles and apparel firms in the overseas markets, the motivation for international market entry was highly found to expand their operation from domestic to international market, and most firms were found to be involved with OEMs(Original Equipment Manufacturers) as an entry mode for international market. China and US market were the most popular market among Korean textiles and apparel firms. Product differentiation strategy, pricing strategy based on manufacturing cost and buyer's offering price, place strategy using foreign buyers and participating a few international exhibition were frequently used among Korean textiles and apparel firms for international marketing. Among textile firms, sales volume was related to product strategies(product development), price strategy(buyer's offer) and place strategy(channel). Among apparel firms, product strategy(product labeling), price strategy(price satisfaction). The findings of this can be used when Korean textiles and apparel firms do strategic planning and evaluate the international marketing strategies. Also information and results of this study may assist policy makers to develop better ideas and strategies for textiles and apparel industry.

• 패션비즈니스
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• 제13권2호
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• pp.17-29
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• 2009

Due to rapid economic growth and accelerated urbanization, numerous cities in China have been turning into huge consumption markets almost simultaneously, and thus, the Chinese apparel markets being globalized are most vigorous in the world, attracting attention from the world apparel industries. If the Korean apparel businesses should develop the products befitting the conditions of the Chinese apparel markets and reflecting her consumers' fashion trends and needs, their apparels would be satisfactory enough to Chinese consumers, being competitive in the Chinese markets. In this sense, today's Chinese apparel markets may well provide the Korean apparel businesses with both crisis and opportunity. As one of the methods to enhance Chinese consumers' satisfaction with the Korean apparels, the Korean apparel businesses should consider seriously about the apparel fitting or a factor determining apparel silhouettes and sense of wearing. Since Chinese consumers differ widely in terms of body types and measurements depending on regions due to the vast territory, differentiation of the apparel fitting is more important than any other single factor, and thus, correct information about apparel fitting may well be directly related with manufacturing of excellent apparels. The purpose of this study is to comparatively analyze the upper body measurements and types of the Chinese and Korean women in their 20's to provide the Korean apparel business engaged in Chinese markets with some basic data about apparel fitting conducive to their development of effective apparel commodities. For this purpose, Chinese women in their 20's living in China's two major cities leading China's women's apparel markets were sampled.