• Title/Summary/Keyword: Inflexin

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Aromatase Inhibitors from Isodon excisus var. coreanus

  • Jeong, Hyeh-Jean;Chang, Leng-Chee;Kim, Ho-Kyoung;Kim, Il-Hyuk;A.Douglas Kinghorn;John M.Pezzuto
    • Archives of Pharmacal Research
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    • v.23 no.3
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    • pp.243-245
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    • 2000
  • The diethyl ether extract of isodon excisus var. coreanus exhibited significant inhibitory activity in aromatase assay. Bioactivity-guided fractionation of the extract led to the isolation of three active compounds: inflexin(ent-1${\alpha}$-hydroxy-3${\beta}$,6a-diacetoxykau r-16-en-11,15-dione) (1), ursolic acid (2), and ursolic acid 3-O-acetate (3).

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