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Adult-onset kaposiform hemangioendothelioma with neurofibromatosis type 1: A case report and literature review

  • Kim, Dong Hwi;Lee, Ji Sung;Shin, Jong Weon;Kim, Jean A;Jun, Young Joon
    • Archives of Plastic Surgery
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    • v.45 no.6
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    • pp.583-587
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    • 2018
  • Kaposiform hemangioendothelioma (KHE) is a very rare, locally aggressive vascular neoplasm. It occurs mostly in children and is rarely observed in adults. It typically originates on the skin, later affecting the deep soft tissue of the extremities, head or neck, and retroperitoneum by infiltrative growth. It is locally aggressive, does not regress spontaneously, and tends to metastasize locally as well as to the regional lymph nodes. In this article, we report a case of adult-onset KHE with neurofibromatosis type 1. The patient presented to our department with a 2-month history of a painful ulceration in her left popliteal area. Since KHE had not previously been reported in patients with neurofibromatosis, the diagnosis was difficult due to the similarity of the skin manifestation to neurofibromatosis-associated lesions. We share our experience of diagnosing and treating this rare case of adult-onset KHE.

Cytologic Findings of Epithelial - Myoepithelial Carcinoma of the Salivary Gland - A Cese Report - (타액선 상피-근상피세포암종의 세포학적 소견 - 1예 보고 -)

  • Nam, Eun-Sook;Kang, Gu;Shin, Hyung-Sik
    • The Korean Journal of Cytopathology
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    • v.7 no.1
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    • pp.64-68
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    • 1996
  • The report of aspiration cytologic findings of epithelial-myoepithelial carcinoma(EMC) in the salivary gland is extremely rare. We present a case of fine needle aspiration cytology(FNAC) from EMC in the right submandibular gland of a 46 years old male patient. Neck CT scan revealed a confined lesion in the submandibular gland without enlargement of the regional lymph node. FNAC from the tumor showed several three-dimensional cellular clusters with admixed normal acinar cells. They frequently formed blanching tubular structures composed of two type of cells; darker cells haying eosinophilic scanty cytoplasm with round dense nuclei and clear cells having abudant pale cytoplasm with vesicular nuclei at the periphery of clusters. The tumor cells of both types did not show pleomorphism or mitoses. The resected submandibular gland showed an ill-defined whitish firm tumor, measuring $2{\times}1.5{\times}2cm$. The histology revealed an infiltrative tumor showing characteristic two cell types in a duct-like arrangement surrounded by thin basement menbrane. An inner layer of darker cells and outer layer of clear cells were postive for cytokeratin in the former and S-100 protein in the taller on the immunohistochemical stain.

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Calcifying Aponeurotic Fibroma : A Case Report

  • Choi, Joon-Hyuk;Seo, Jae-Sung;Cho, Kil-Ho
    • Journal of Yeungnam Medical Science
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    • v.20 no.2
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    • pp.223-228
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    • 2003
  • Calcifying aponeurotic fibroma is a rare benign soft tissue tumor that usually involves distal extremities in children and adolescents, especially the hands and feet. We report a case of calcifying aponeurotic fibroma arising in a 14-year-old boy who complained of right thumb mass. Surgical excision was performed. The resected specimen showed a $2.0{\times}1.5cm$ grayish white, fibrotic tissue. Histologic examination showed proliferation of fibroblastic cells with infiltrative growth pattern. Foci of calcification and chondroid differentiation were present.

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Study for defensive effect of Jowesungcheong-tang on gastric mucosal damage in mice (조위승청탕(調胃升淸湯)의 위점막(胃粘膜) 손상(損傷) 방어효과(防禦效果)에 관한 연구(硏究))

  • Park, Seoung-Sik;Han, Jin-Soo
    • Journal of Sasang Constitutional Medicine
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    • v.14 no.1
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    • pp.100-111
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    • 2002
  • 1. The Purpose of study An experimental study has done to examine the effect of defense on gastric mucosal damage of Jowesungcheong-tang. 2. The Material and Method of study Mice had intragastric injected with JST extract before indome thacin treatment which induces hemorrh age erosion artificially. General morphology, infiltrative cell in mucosa, the distribution of UEA-I, COX-1, MAC-1. ICAM, and Apoptotic cell were objected (Ahhreviation) JST :Jowesungcheong-tang, UEA-I : ulex europaeus agglutinin-I, COX-1: cyclooxyhenase-1, ICAM : intercellular adhesion molecule-1, GPE : Gastropathy elicitated mice 3. The results and Conclusions of study 1) The degree of hemorrhage erosion in GPE-group had increased conspicuously in gastric gland proper. JST -group were the same as normal 2) The noticeable increase of granular lecocytes and lymphocytes in GEP-group were seen, but in JST group, the configuration is decreased 3) The decrease of UEA-I positive reacted cells, COX-1, surface epithelial cells and the increase of MAC-l positive cells, ICAM-l positive cells had shown in GPE-group, but in JST-group UEA-I positive cells, COX-1 surface epithelial cells were in creased and MAC-1 positive cells, ICAM-l positive cells were decreased than GPE-group. 4) A number of apoptotic cells were distributed in hemorrhage erosion. The remarkable decrease of apoptotic cells were shown in JST-group.

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ODONTOGENIC MYXOMA OF THE MANDIBLE: REPORT OF A CASE (하악골에 발생한 치성점액종: 증례보고)

  • Han, Kwang-Heung;Yoon, Kyu-Ho;Jung, Jung-Kwon;Bae, Jung-Ho;Jang, Jung-Yong;You, Myung-Soo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.27 no.1
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    • pp.81-84
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    • 2005
  • Odontogenic myxoma is a benign neoplasm composed of a uniform myxoid appearance that is believed to arise from the primitive mesenchymal portion of the tooth germ. It appears as painless swelling, but it should be distinguished from cystic lesion or other benign tumor. Although odontogenic myxoma is benign, its behavior is known to be aggressive and infiltrative, so thorough curettage and enucleation is necessary. We report a case of odontogenic myxoma of the mandible observed in our clinic with good prognosis after enucleation was done.

Breast Cancer in Ardabil Province in the North-West of Iran: an Epidemiological Study

  • Fouladi, Nasrin;Pourfarzi, Farhad;Amani, Firooz;Ali-Mohammadi, Hossein;Lotfi, Ilshan;Mazaheri, Effat
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1543-1545
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    • 2012
  • Breast cancer accounts for about 26% of all newly diagnosed cancers in women aged 20 to 59 years. As part of a basic program for cancer control, the present cross sectional descriptive study was conducted with the objective of determining the epidemiology of breast cancer in Ardabil province during 2003-2010. Necessary information on 469 recorded cases of breast cancer in the registry were collected by check list from patient's files and then analyzed by statistical methods with SPSS.16 software. Some 455 of the patients (97%) were female, 329 (70.1%) residing in Ardabil. The mean age was $46.8{\pm}13.6$ and most were in the age group of 40 - 60. The most prevalent pathologic form was infiltrative ductal carcinoma with 316 cases (67.4%), the largest proportion being grade II (30.6%), but very many belonged to grades III and IV (40.5%). Breast cancer in Ardabil province appeared to slightly increase over the period studied. The results were similar to other places in Asia. With regard to this, more widespread studies are required to determine factors influencing the prevalence at low age and also how to promote early detection.

A Case of Basal Cell Adenocarcinoma Arising from the Bilateral Parotid Gland (양측 이하선에서 발생한 기저세포선암 1예)

  • Yun, Ju Hyun;Lee, So Jeong;Park, Sohl;Kim, Han Su
    • Korean Journal of Head & Neck Oncology
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    • v.36 no.1
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    • pp.15-19
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    • 2020
  • Basal cell adenocarcinoma is 1 ~ 2 % of salivary gland carcinoma. It was recently classified as low grade malignancy. It is low grade malignant counterpart of basal cell adenoma. It has similar morphologic attributes with basal cell adenoma, but it has distinctive malignant potential including infiltrative growth into surrounding tissues and distant metastasis. Recently, we have experienced a case of basal cell adenocarcinoma arising from the bilateral parotid gland in a 38-year old woman who was previously operated on superficial parotidectomy due to pleomorphic adenoma. We report this rare case with a review of literature.

A Case of Nasal Diffuse Large B-Cell Lymphoma in a Cat

  • Kim, Seong-Jun;Kim, Jun-Young;Oh, Dong-Keun;Cho, Jun-Ho;Park, Hee-Myung;Kang, Min-Hee
    • Journal of Veterinary Clinics
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    • v.35 no.4
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    • pp.141-143
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    • 2018
  • A 6-year-old spayed female Turkish Angora cat presented with sneezing, nasal discharge, and decreased appetite lasting for 21 days. Skull radiography revealed slightly increased density of soft tissue in the left nasal cavity. Computed tomography (CT) scan revealed an extensive mass with nasal septum destruction and moderate contrast enhancement in the left nasal cavity. After surgical biopsy, histopathological examination confirmed that the mass was an infiltrative round cell neoplasm, composed of sheets of large neoplastic cells. Immunohistochemical analysis revealed that most of the neoplastic cells were strongly positive for CD79a and weakly positive for PAX5. Additionally, numerous mature lymphocytes were found to be positive for CD3. This is the first reported case of nasal diffuse large B-cell lymphoma (DLBCL) in a Turkish Angora cat in Korea.

AMELOBLASTIC FIBROMA OF THE MANDIBLE BODY : A CASE REPORT (하악골체에 발생한 법랑아세포성 섬유종의 증례보고)

  • Jang, So-Jeong;Baek, Jin-A;Leem, Dae-Ho;Shin, Hyo-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.27 no.5
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    • pp.482-487
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    • 2005
  • Amelobalstic fibroma is a rare true mixed tumor of odontogenic origin with both mesenchymal and ectodermal components. It usually appears in the mandible and in the posterior segments of young patients without gender predilection, and sometimes is associated with an impacted tooth. It is a benign slow growing tumor that is less infiltrative than an ameloblastoma but tends to expand bone. Surgical treatment with excision followed by curettage seems to be the most appropriate therapeutic option. The objective of this presentation is to report a case of ameloblastic fibroma of the mandible body in a 14-year-old woman, to make a brief review of the literature about its differential diagnosis and its clinical and histologic features and the treatment.

Primary Intramedullary Spinal Sarcoma : A Case Report and Review of the Current Literatures

  • Kim, Su-Hyeong;Bak, Koang-Hum;Kim, Dong-Won;Kang, Tae-Hoon
    • Journal of Korean Neurosurgical Society
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    • v.48 no.5
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    • pp.448-451
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    • 2010
  • Primary central nervous system (CNS) sarcomas are exceedingly rare, and, to the best of our knowledge, there has not yet been a report of intramedullary sarcoma. Here, we report a primary intradural intramedullary sarcoma of the spinal cord in a four-year-old boy who presented with low back pain and a radiculopathy involving both lower extremities. The tumor showed significant enhancement on magnetic resonance (MR) images due to its extreme vascularity. Gross total tumor removal was performed with microelectrical pulse recording, and the patient also received adjuvant radiotherapy and chemotherapy. After the operation, the patient's sensory deficits were improved. Because CNS dissemination is common, entire neuraxis evaluation is essential, although there was no evidence of dissemination in this case. The prognosis of primary CNS sarcoma is poor due to infiltrative nature and early CNS dissemination is common, and the treatment of choice is radical surgical resection. Adjuvant therapy is also beneficial with radiotherapy and chemotherapy.