• 대한수의학회지
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• 제15권2호
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• pp.215-222
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• 1975

Infertility and breeding status of Korean cows which are reared in a extensive alpine ranches of Daegwanryeong area was investigated. The results obtained were summarized as follows, 1. Infertility frequency of the cows was 25.9% against a total examined number of 675 heads, and was 17.6% against a total rearing number. 2. The distributions of infertile cows 44.6% of Granular vaginitis-like syndrome, 36% of repeat breeder, 8.6% of symptom of ovary, 6.8% of symptom of uterus and 4% of other symptoms. 3. According to its age were found by 51.4% upon 2 years of age, 30.3% upon 3 years of age, 11.4% upon 4 years of age and 6.9% upon S years of age. 4. Breeding status of Korean cows showed 74.1% of conception rate in the cases of pre-treatment, while breeding status increased markedely in the cases of post-treatment by the 85.8%. 5. The conception rate by the artificial insemination mainly on the first mating was 36.1%. on the second mating 23.0% and on the third mating 18.0%. Total conception rate between first and third mating was 77.1%. 6. The therapeutic effect by treatment for granular vaginitis-like syndrome was 87.1%.

• 한국발생생물학회지:발생과생식
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• 제3권1호
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• pp.1-13
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• 1999

남성 불임에 있어서 유전적 결함은 중요한 요인 중 하나이다. 정자 형성은 매우 복잡한 과정을 거치므로 생식세포의 완전한 발달을 조절하는데 많은 유전자들이 관여할 개연성이 높다. 이들 유전자 중에서 불임 유발 유전자는 다른 기능은 정상이되 생식에만 제한적으로 영향을 미치는 유전자들로 정의될 수 있다. 불임 남성에게서 Y 염색체의 미세결실(microdeletion)이 자주 관찰되었고, RBM과 DAZ라는 유전자가 그 위치에 존재함이 알려졌다. 또한 상 염색체에 존재하는 유전자를 인위적으로 변이시킨 생쥐들 가운데 표현형이 웅성불임으로만 국한하여 나타나는 경우가 있는데, 이런 유전자들도 남성 불임 유전자의 후보로 간주할 수 있으며, 실제로 이 유전자들의 변이에 말미암은 남성 불임 환자도 적지 않을 것으로 사료된다.

• Reproductive and Developmental Biology
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• 제29권4호
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• pp.269-271
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• 2005

The freemartinism is the most frequent form of intersexuality found in cattle, and females of heterosexual twins become sterile. With increase of twinning rates due to transfer of multiple embryos derived from in vitro fertilization, it is of great economic value to establish early diagnosis of freemartins to remove infertile individuals from breeding stock. In the present study polymerase chain reaction (PCR) of two different Y-chromosome specific segments (BRY.l and AMX/Y) was performed to identify freemartins from twins and less common single born freemartins in Korean Native Cattle (KNC). Two male-specific sequences were amplified in all heterosexual twins tested (n=5). In addition, Y-specific PCR products were detectable in one of the single born females (n=4) with visible genital abnormalities. These results suggest that the sensitivity of PCR-based assay may be sufficient to detect freemartinism in single born females as well as female partners of heterosexual twins in KNC.

• 대한한방부인과학회지
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• 제23권3호
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• pp.213-220
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• 2010

Purpose: To report the effect of oriental medicine on a infertile patient with endometriosis diagnosed as a IVF case due to pelvic adhesion. Methods: The patient who had infertility problem with pelvic adhesion from endometriosis in spite of 2 times of IVF trials was treated with the oriental medicine such as herbal medication, herbal acupuncture and moxibustion therapy, and so forth. Results: After the oriental medical treatments, the patient could give a natural birth to a healthy baby. Conclusion: This case report shows that the oriental medical treatment is effective for treating infertility of endometriosis with pelvic adhesion.

• 대한한의학회지
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• 제36권2호
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• pp.1-7
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• 2015

Objectives: To report on the result of infertility treatment with Korean medicine in clinical settings. Methods: This study was single arm, retrospective observational study. Analysis of the medical records on thirty four infertile women who were treated by acupuncture, moxibustion, herbal medicine(Jokyungjongoktang-gagambang, Sutaehwan-gagambang). Pregnancy rate(PR) and Live birth rate(LBR) were analyzed as the primary outcomes. Changes of AMH, FSH, LH, $E_2$, $P_4$, endometrial thickness, fat mass, and BMI were also analyzed as the secondary outcomes. Results: A total of 34 patients were treated in the traditional Korean medical clinic. Nine patients were dropped, and 25 subjects completed the final examination at the end of this treatment schedule. Five of 25 subjects conceived during treatment, reaching 20% PR and LBR was also 20%. Except for FSH level, the results of the remaining outcome measures, including LFT, showed no significant changes. No serious adverse event has been reported. Conclusion: Although no significant changes in bio-markers were observed, complex treatment using Korean medicine has shown effectiveness on women's infertility. In addition, the safety of the treatment has been verified.

• 대한본초학회지
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• 제35권5호
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• pp.41-46
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• 2020

Objectives : According to 2013 statistics, the primary infertility rate is 13.5%. The current situation is much worse than that reported, so it is even emerging as a social problem. The purpose of this study is to analyze the 5 cases of successful infertility treatment with herbal treatment and to give hope to the infertile couple to become pregnant and to suggest the possibility of herbal treatment in infertility treatment. Methods : We administered Jokyungjongok-tang gamibang as a herbal medicine and treated with acupuncture, moxibustion. Treatment was done once or twice a week. The herbal medicines were taken 30 minutes after meals and 3 times a day. While taking the herbal medicine, they were prohibited from eating flour, pork, liquor, tobacco and coffee. Patient status was assessed by consultation through pulse, tongue and abdominal diagnosis. The diagnosis of pregnancy was confirmed by ultrasonography at hospitals and the success of the treatment was judged based on healthy birth. Results : Patients had common features, such as lower abdominal pain, menstrual cramps, and blood clots during menstruation. Herbal medicine combined with acupuncture, moxibustion improved patients' overall fatigue and reduced the body's coldness. Since then, the dysmenorrhea and blood clots have decreased, and the digestion condition has improved. Therefore they became pregnant and gave birth to a healthy baby. Conclusion : Jokyungjongok-tang gamibang was effective in improving the body's coldness and uterine condition and was successful in pregnancy and helped to give birth to a healthy baby.

• Clinical and Experimental Reproductive Medicine
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• 제26권1호
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• pp.97-101
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• 1999

Male genital tract inflammatory conditions may be associated with unexplained infertility. The presence of cytokine such as tumor necrosis factor-alpha (TNF-${\alpha}$) was reported in the semen of infertile men. However, the effect of these cytokines on human sperm function is still unclear. The purpose of this study was to investigate the in-vitro effects of TNF-alpha on human sperm motility with computer assisted sperm analysis. Washed sperm from 16 normal men were incubated without and with TNF-${\alpha}$ (0.1, 10, 1000 ng/ml). The changes of parameters of sperm motility were recorded at different time intervals (0, 5, 24 hour). There was no significant change of parameters of sperm motility in the incubation with TNF-${\alpha}$. It is suggested that TNF-${\alpha}$ alone does not interfere with the sperm motility and more studies are needed.

• Clinical and Experimental Reproductive Medicine
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• 제17권2호
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• pp.145-151
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• 1990

This study was carried out to elevating the pregnancy rate in infertile patient by Gamete intrafallopian transfer (GIFT). The GIFT program was performed from July 1988 to June 1990. Of the 131 cycles, the mean age of patient was 31.6 years and the mean duration of infertility was 5.3 years. 41 patients became pregnant, for a pregnancy rate of 31.3%. 5 preclinical abortions and 6 clinincal abortion was occured. 2 ectopic pregnanices and 1 combined pregnancy were occured. 7 twin pregnancies and 1 triplet were occured (multiple pregnancy rate;22.2%). 11 pregnancies were term delivered, 17 are ongoing pregnancies. GIFT may be considered as an alternative to in vitro fertilazation in infertility cases in which at least one fallopian tube is patent.

• Clinical and Experimental Reproductive Medicine
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• 제40권4호
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• pp.143-147
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• 2013

Oocyte in vitro maturation (IVM) is an assisted reproductive technology in which oocytes are retrieved from the antral follicles of unstimulated or minimally stimulated ovaries. IVM of human oocytes has emerged as a promising procedure. This new technology has advantages over controlled ovarian stimulation such as reduction of costs, simplicity, and elimination of ovarian hyperstimulation syndrome. By elimination or reduction of gonadotropin stimulation, IVM offers eligible infertile couples a safe and convenient form of treatment, and IVM outcomes are currently comparable in safety and efficacy to those of conventional in vitro fertilization. IVM has been applied mainly in patients with polycystic ovary syndrome or ultrasound-only polycystic ovaries, but with time, the indications for IVM have expanded to other uncommon situations such as fertility preservation, as well as to normal responders. In this review, the current clinical experiences with IVM will be described.

• The Korean Journal of Ecology
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• 제7권2호
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• pp.67-73
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• 1983

Jeju-Do is a volcanic island of which climate is very warm and humid, but Opuntia lanceolata Haw, showing CAM metabolism is growing at Wolyung-Ri, Hanrim-Eup, Jeju-Do. Annual productivity of Opuntia was 696.47g/m2/yr and 533.47g/m2/yr at two populations on the seashore respectively and 414.92g/m2/yr on the basalt wall of a village. Stem area index was 13.74, 6.93, and 9.30 at each population which are higher values than average range of leaf area index. The standing crop was the highest at the second cladode from the cladode showed little difference at most chemical properties of P, K, Ca and Na. Total nitrogen contents were the most at the youngest cladode and the lest at the oldest one. Soils were infertile of which organic contents were 1.5% and 5.0% on the seaside and the basalt wall respectively. The soil on the basalt wall contained little water whose water contents were 0.9% and at seashore population 15.12% of water contents were. Furthermore high exchangeable Na contents in soil added waer deficiency.