• Parasites, Hosts and Diseases
• /
• v.59 no.6
• /
• pp.595-605
• /
• 2021

An understanding of the knowledges, attitudes and perceptions of different populations is key for public health policy makers. Here, a survey was performed on knowledge, attitudes, and perceptions about malaria diagnosis, prevention, control, and treatment. The 407 survey participants included both uninfected inhabitants and patients from 2 cities (Gimpo- and Paju-si) of Northern Gyeonggi-do, known as high-risk areas for vivax malaria. We used community-based study design and non-probability sampling method using the primary data. Association between variables were tested using χ²-tests. In general, the information on malaria reported by the participants in this study was unsystematic and included inaccurate details. The knowledge of malaria symptoms, identified as headache, chills and fever, was high, but the surveyed community lacks knowledge of the specific medications used for malaria treatment, with a large number of respondents having no knowledge of any form of medication. Survey questions with high correct answer rates included questions about easy treatment of malaria in Korea, the high daytime activity of malaria-borne mosquitoes, and the infection risk posed by outdoor activities. However, a large portion of the respondents was unable to provide simple medical and biological information about the disease. This study aimed to comprehensively evaluate the knowledge, attitude, and practical behavior of the surveyed community with respect to malaria and the implications reported here could be applicable to other malaria endemic areas in Korea.

• Korean Journal of Veterinary Service
• /
• v.30 no.3
• /
• pp.321-327
• /
• 2007

This is a case report on the occurrence of inclusion body hepatitis (IBH) and infectious bursal disease (IBD) among the broilers in a local farm located in Wanju, Jeollabukdo. Mostly IBH could be caused by adenovirus if the bird's immune system was first weakened by exposure to immunosupressive agents such as infectious bursal disease virus (IBDV) and chicken anemia virus (CIAV). However IBH primary occurred before IBD in this case. And recent work has demonstrated that virulent adenovirus alone can produce the disease.

• Journal of Korean Public Health Nursing
• /
• v.24 no.1
• /
• pp.115-125
• /
• 2010

Purpose: This study was conducted to investigate the knowledge of infectious diseases and the management of children with infectious diseases among daycare facility teachers. Methods: This study was based on survey questionnaires completed by 122 day care facility teachers from 36 daycare center sin one district in Seoul. Results: Seventy three (72.8%) of the participating daycare facility teachers had not received infectious disease prevention education. They recognized that they did not have enough knowledge of infectious diseases. The average knowledge level of infectious diseases was scored as 9.30 on a 0-30 scale, with 0 representing no knowledge and 30 expert knowledge, and compliance level of management of children with infectious diseases was scored as 4.29 on a 0-16 scale, with 0 present no compliance and 16 representing total compliance Confidence of management of children with infectious diseases (r=0.24, p=.031) and the compliance level of management (r=0.35, p=.001) were higher with increased knowledge of infectious diseases. Conclusions: Daycare facility teacher scan lack sufficient knowledge about b infectious diseases. The education about infectious diseases and management of children with infectious diseases is indispensable to prevent trans mission of infectious diseases in daycare facilities.

• Journal of Home Health Care Nursing
• /
• v.28 no.2
• /
• pp.154-163
• /
• 2021

Purpose: This study aimed to verify the effects of nurses' COVID-19 related stress, hardiness, and organizational citizenship behavior on nursing intention in infectious disease hospitals. Methods: The participants were 182 nurses. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and multiple stepwise regression analysis with the SPSS program. Results: The nursing intention of nurses differed significantly by age (p=.013), marital status (p=.002), clinical career (p=.018), job position (p=.005), and experience of education for infectious disease management (p=.016). A statistically significant positive correlation was observed between nursing intention and COVID-19 related stress(r=.18), and between nursing intention and organizational citizenship behavior(r=.43). COVID-19 related stress, and organizational citizenship behavior explained 21% of the nursing intention. Conclusion: Based on the above results, improve the nursing intention of infectious disease hospital nurses exposed to risk, and it is necessary to manage inadequate stress of infectious diseases and cultivate organizational citizenship behavior.

• Journal of Veterinary Science
• /
• v.21 no.2
• /
• pp.19.1-19.10
• /
• 2020

Given that the current Newcastle disease virus (NDV) infection in wild birds poses the threat to poultry, surveillance of Newcastle disease in captive wild birds was carried out in Jilin, China in 2018. Here, an NDV strain obtained from toco toucan was firstly characterized. The results showed that the F gene of the NDV isolate Toucan/China/3/2018 is classified as genotype II in class II. Sequence analysis of the F0 cleavage site was ¹¹³RQGR/L¹¹⁷, which supports the result of the intracerebral pathogenicity index assay indicating classification of the isolate as low-pathogenicity. Experimental infection demonstrated that Toucan/China/3/2018 can effectively replicate and transmit among chickens. To our knowledge, this is the first report on genetically and pathogenically characterizing NDV strain isolated from toucan, which enriches the epidemiological information of NDV in wild birds.

• Health Policy and Management
• /
• v.32 no.4
• /
• pp.380-388
• /
• 2022

Background: Emerging infectious diseases, such as Middle East respiratory syndrome or coronavirus disease 2019, pose a continuous threat to public health, making a risk assessment necessary for infectious disease control and prevention. Therefore, we aimed to investigate the risk assessment methods for infectious diseases used by major foreign countries and organizations. Methods: We conducted an investigation and comparative analysis of risk assessment and risk determination methods for infectious diseases. The risk assessment tools included the strategic toolkit for assessing risks, influenza risk assessment tool, pandemic severity assessment framework, and rapid risk assessment methodology. Results: The most frequently reported risk elements were disease severity, antiviral treatment, attack rate, population immunity, and basic productive ratio. The risk evaluation method was evaluated quantitatively and qualitatively by the stakeholders at each institution. Additionally, the final risk level was visualized in a matrix, framework, and x and y-axis. Conclusion: Considering the risk assessment tools, the risk element was classified based on the duplicate of each indicator, and risk evaluation and level of risk assessment were analyzed.

• IMMUNE NETWORK
• /
• v.23 no.4
• /
• pp.33.1-33.13
• /
• 2023

Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been acknowledged as an effective mean of preventing infection and hospitalization. However, the emergence of highly transmissible SARS-CoV-2 variants of concern (VOCs) has led to substantial increase in infections among children and adolescents. Vaccine-induced immunity and longevity have not been well defined in this population. Therefore, we aimed to analyze humoral and cellular immune responses against ancestral and SARS-CoV-2 variants after two shots of the BNT162b2 vaccine in healthy adolescents. Although vaccination induced a robust increase of spike-specific binding Abs and neutralizing Abs against the ancestral and SARS-CoV-2 variants, the neutralizing activity against the Omicron variant was significantly low. On the contrary, vaccine-induced memory CD4⁺ T cells exhibited substantial responses against both ancestral and Omicron spike proteins. Notably, CD4⁺ T cell responses against both ancestral and Omicron strains were preserved at 3 months after two shots of the BNT162b2 vaccine without waning. Polyfunctionality of vaccine-induced memory T cells was also preserved in response to Omicron spike protein. The present findings characterize the protective immunity of vaccination for adolescents in the era of continuous emergence of variants/subvariants.

• Korean Journal of Veterinary Research
• /
• v.41 no.3
• /
• pp.333-342
• /
• 2001

To detect the genetic variations among infectious bursal disease (IBD) vaccine strains, the hypervariable region of VP2 gene of seven IBDV vaccine strains were amplified using reverse transcriptase/polymerase chain reation(RT/PCR). Ampllified PCR products of IBDV were cloned, sequenced, and compared with published sequences for IBDV. Vaccine strains (JOONG, HAN, B7, IB, BU2, G2, CIL) used in Korea and Korean field isolates (SH/92, K1, 310) had 81%(310 and HAN) ~ 98%(SH/92 and CIL) amino acid sequence similarity. Vaccine strains had 80%(HAN and IB) ~ 99%(JOONG and BU2) amino acid sequence similartiy. Intermediate plus vaccine strain, CIL was not substituted at positions 279(D $\rightarrow$ N) and 284(A $\rightarrow$ T), and conserved in serine-rich heptapeptide. At the two hydrophilic region, JOONG, IB and Bu2 strains had identical amino acid sequence comparing with STC strain. By phylogenetic analysis, JOONG and DAE strains were categorized in same group with BU2. The CIL and STC strains closely related but seperated from G2, HAN, B7 and IB strains.

• Korean Journal of Veterinary Research
• /
• v.59 no.4
• /
• pp.207-211
• /
• 2019

Mass mortality in commercially cultured Amur catfish (Silurus asotus), showing symptoms of dermal ulcerations, occurred on a private farm in Mar 2019 in Korea. β-hemolytic bacteria were isolated from the ulcers and kidneys of the fish and identified as Aeromonas veronii. The isolate was resistant to tetracycline and possessed cytotoxic heat-labile enterotoxin (aerolysin/hemolysin). We investigated the genetic determinants associated with tetracycline resistance, and the isolate has been confirmed to simultaneously possess tetA and tetE genes. This is the first report on the occurrence of tetracycline-resistant A. veronii infection related to mass mortality in commercially cultured Amur catfish in Korea.

• Korean Journal of Veterinary Service
• /
• v.21 no.3
• /
• pp.277-284
• /
• 1998

Serum samples were collected from 100 breeders and their progeny 600 broilers. The breeders and broilers were vaccinated against infectious bronchitis(IB), infectious bursal disease(IBD) and Newcastle disease(ND) viruses according to general vaccination program. The antibodies in serum samples against IB, IBD and ND viruses were detected by ELISA using commercial ELISA kit. Geometric mean titer(GMT) of ELISA was monitored from 1-day-old to 35-day-old broilers and compared to that of breeder chickens. The GMT of ELISA to IB, IBD and ND was declined half level of the day old broiler's antibody titers at about 4, 9 and 4 days of age. The GMT of ELISA to IB, IBD and ND was declined than that of protective antibody titer at about 12, 11, and 15 days of age. Thereafter, the GMT of ELISA to IB, ND were declined and disappeared according to age of broilers. The GMT of ELISA to IBD was declined according to age of broilers, but at 25 days of age increased and 31 days of age increased than that of protective antibody titer. Taken together, these studies led to conclusion that time-course of antibody titers of broilers from vaccinated breeders and that of progeny broliers which vaccinated according to vaccine program. Those are very important data to design vaccine program to breeders and broilers.