• Korean Journal of Medicinal Crop Science
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• v.19 no.3
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• pp.191-197
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• 2011

In this study, we investigated antioxidant activities and whitening effects of Acer mono sap by encapsulation of nanoparticles. Acer mono sap was through ultra high pressure process and then encapsulated by lecithin. Nano-encapsulated The nanoparticles of Acer mono sap showed highest free radical scavengering effect as 89.7% in adding sample (1.0 mg/ml), compared to sap of non-encapsulation. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 47.8%. High inhibitory of tyrosinase was also measured as 85.8% by adding lecithin nano-particle of 1.0 mg/ml. The nano-particles also showed 14.8% of low cytotoxicity against human normal fibroblast cells in adding 1.0 mg/ml of the highest concentration. These results indicate that Acer mono sap may be a source of cosmetic agents capable of improving whitening effect and antioxidant activites.

• Korean Journal of Medicinal Crop Science
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• v.19 no.4
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• pp.264-270
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• 2011

In this study, we investigated the cosmetic application of Acer mono sap through an ultra-high pressure process. Exposing Acer mono sap to a ultra-high pressure process resulted in 90.1% cell viability of human normal fibroblast cells (CCD-986sk) when added at the highest concentration. Acer mono sap also showed the hightest free radical scavenging activity after the ultra high pressure process. The melanogenesis inhibition rate in cloned M-3 cells was 59.0%. Tyrosinase was inhibited at a rate of 87.2% by adding 100% HPAMS. Anti-wrinkle activity was 78.1%. Acer mono sap showed enhanced storage following the ultra high pressure process. These results indicate that Acer mono sap may be a source for functional cosmetic agents capable of improving antioxidant, whitening, and antiwrinkling effects.

• Journal of the Korean Data and Information Science Society
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• v.22 no.2
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• pp.323-333
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• 2011

Recently, Electronic Data Interchange (EDI) systems are widely used. Many organizations exchange the documents by using EDI, and EDI is used in various industries such as physical distribution, export and import business, custom, and medical care. However, there have been little attempt to empirically investigate the success factors of EDI system. In this paper, we identify the influencing factors which determine the success of typical information system and then suggest the additional factors characterized to the EDI system. Our research model, mainly based on the system success model, is tested by analyzing the empirical data acquired from the companies in the medical industry. As a result, the system quality, information quality, service quality, and the perceived sacrifice turned out to be significant to the success of EDI system while data security does not. The result of this research is likely to help providing useful guidelines for the successful EDI implementations.

• Journal of radiological science and technology
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• v.28 no.3
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• pp.193-201
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• 2005

We are living in Ubiquitous society now. There is also trend of integration in medical field that is largely affected by outside environment. At this time, it is necessary to rightly understand the abstract, function, expected effect and management method of Integration Medical Information System(IMIS) to use this system effectively for solving many hospital information system problems and disadvantages. It is fact that large-sized hospitals are improving the quality of service for treatment of patients through building integrated Medical Information System. So it is necessary to change this individual system that is previously developed and used for treatment assistance, hospital affair or general management respectively to integrated management system, modify patient information or treatment information data to the data suitable for new system and build the integrated medical information system suitable for the hospital service with treatment data and integrated medical information. This paper suggested and designed abstract of integrated medical information system, the organization of system, the character of system and the plan and materialization of IMIS when building integrated medical information system. And the context of this paper is suggested trend of industry and solution of integration EMR, HIS, PACS. Therefore this paper is suggested development strategy, implemented integration medical information system.

• The Journal of Industrial Distribution & Business
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• v.9 no.8
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• pp.7-16
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• 2018

Purpose - The effect of regional culture has been acknowledged for decades. However, very little research takes it as an important issue in the medical tourism service decision process. This study focuses on regional culture to identify customers' preference for medical tourism in the international environment. It is proposed that regional culture may work as an critical moderator in the international medical tourism destination choice process. Especially, the destination attributes may vary according to regional culture. Research design, data, and methodology - By the questionnaire survey, the sample is collected from 2,041 potential Chinese residents in different regions of China. Regression analysis is constructed to test the effect of regional culture on Chinese customers' destination preference. Results - Results imply that regional culture plays a critical moderating role in the destination choice process. Results also indicate that destination attributes including medicine and travel characteristics are the important predictors of destination preference. Conclusions - This study provides the fundamental base to use regional culture as a descriptive variable for segmentation when establishing an effective marketing strategy. Furthermore, this research suggests that different strategies relied on destination attributes should be made to attract more Chinese customers for the development of medical tourism industry.

• Journal of Ginseng Research
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• v.45 no.6
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• pp.654-664
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• 2021

Background: Ginsenoside Rg3, isolated from Panax ginseng, has anti-inflammatory and anti-tumor activities. It is known to reduce inflammation in acute lung injury in mice, and to reduce the expression of inflammatory cytokines and COX-2 in human asthmatic airway epithelium. In this study, we attempted to determine whether ginsenoside Rg3 inhibits airway inflammation, oxidative stress, and airway hyperresponsiveness (AHR) in the lungs of asthmatic mice. We also investigated its effects on oxidative stress and the inflammatory response in tracheal epithelial cells. Methods: Asthma symptoms were induced in female BALB/c mice sensitized with ovalbumin (OVA). Mice were divided into five groups: normal controls, OVA-induced asthmatic controls, and asthmatic mice treated with ginsenoside Rg3 or prednisolone by intraperitoneal injection. Inflammatory BEAS-2B cells (human tracheal epithelial cells) treated with ginsenoside Rg3 to investigate its effects on inflammatory cytokines and oxidative responses. Results: Ginsenoside Rg3 treatment significantly reduced eosinophil infiltration, oxidative responses, airway inflammation, and AHR in the lungs of asthmatic mice. Ginsenoside Rg3 reduced Th2 cytokine and chemokine levels in bronchoalveolar lavage fluids and lung. Inflammatory BEAS-2B cells treated with ginsenoside Rg3 reduced the eotaxin and pro-inflammatory cytokine expressions, and monocyte adherence to BEAS-2B cells was significantly reduced as a result of decreased ICAM-1 expression. Furthermore, ginsenoside Rg3 reduced the expression of reactive oxygen species in inflammatory BEAS-2B cells. Conclusion: Ginsenoside Rg3 is a potential immunomodulator that can ameliorate pathological features of asthma by decreasing oxidative stress and inflammation

• Journal of Radiation Industry
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• v.12 no.4
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• pp.337-341
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• 2018

Sector block is not used for Gamma Knife surgery in patients with generalized trigeminal neuralgia but sector block is used to reduce the dose reaching the brain stem when the trigeminal ganglgia and the 'Brain stem', radiation sensitive tissue, are adjacent. In the Gamma Knife surgical plan of this study, a surgical plan was established using a Leksell Gamma Plan 11. 1.0 (Elekta Instrument AB, Sweden) with one patient (Block unused, Brain stem dose No volume over 12 Gy, Case 1) who did not need a sector block and four patients (Block unused, Brain stem dose 12 Gy or more, Case 2~5) with a sector block. Magnetic resonance images were obtained by MPRAGE T1 and CISS Respectively. When the trigeminal ganglion is in close proximity to the brain stem, the brain stem volume is decreased when the sector block is used, while the treatment time was increased. In conclusion, This Study evaluates the usefulness of the Sector block in brain stem through Gamma Knife surgery in trigeminal neuralgia, which is considered to be the most important factor for the Gamma Knife surgery.

• Biomedical Science Letters
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• v.23 no.4
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• pp.355-361
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• 2017

In this study, antioxidant and anti-inflammatory of fermented Houttuynia cordata Thunb and scoria mixture extract were investigated in vitro. Radical-scavenging activities of the ethanol extracts were examined by using ${\alpha},{\alpha}$-diphenyl-${\beta}$-picrylhydrazyl (DPPH) and 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS)) radicals assay. Consequently, we confirmed that fermented Houttuynia cordata Thunb and scoria mixture extract dependent removed DPPH and ABTS radical. Also, to confirm anti-inflammatory activity of ethanol extract, we treated fermented Houttuynia cordata Thunb and scoria mixture extract on BV-2 cell with LPS. The result showed that fermented Houttuynia cordata Thunb and scoria mixture extract concentration-dependent inhibited NO production. Therefore, fermented Houttuynia cordata Thunb and scoria mixture extract showed inhibition radical oxygen activities and inflammatory and have available for a pharmacological composition on neuritis-protection and treatment.

• Journal of Convergence Society for SMB
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• v.4 no.2
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• pp.19-24
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• 2014

Recently the government aims to new markets, new jobs, and economic management based on technology, imagination, and creativity through the 'Creative Economy'. It has also been demonstrated in the creation of economic benchmarking of the developed countries that the performance of the creative economy in the border area with convergence of industry, science, culture and technology can achieve. In particular, women in science and technology play an important role in the case of developed countries. However, it is known that active supports and development policies for women scientists and engineers are insufficient, and the number of woman in science and technology is very low in korea. The ratio of women in her early and mid 30s in economic activity is low because of career break and difficulties from going back to work due to childbirth and parenting. The government should concentrate on the creative education and training, support for women in science and technology to develop the creative economy progressively. we present the investigation of the ICT industry status, role of women in economic participation, and the plan of creating jobs for women in the ICT industry in this paper.

• Journal of Contemporary Eastern Asia
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• v.13 no.1
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• pp.19-37
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• 2014

In an attempt to develop comprehensive evidence-based methods for evaluation of the R&D performance of cross-disciplinary projects, a joint bibliometric analysis of patents and publications was performed for two industry-university-government collaborative projects aimed at commercialization: Hokkaido University Research & Business Park Project (2003-2007; 63 inventors; 176 patents; 853 papers), and Matching Program for Innovations in Future Drug Discovery and Medical Care - phase I (2006-2010; 46 inventors; 235 patents; 733 papers). Besides the simple output indicators (for five years period), and citations (from the publication date to the end of 2012), science maps based on the network analysis of words and co-authorship relations were generated to identify the prominent research themes and teams. Our joint analysis of publications and patents yields objective and mutually complementing information, which provides better insights on research and commercialization performance of the large-scale projects. Hence, such analysis has potential for use in the industry-university project's performance evaluation.